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2023 Journal Article Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndromeHealy, Michael D., McNally, Kerrie E., Butkovič, Rebeka, Chilton, Molly, Kato, Kohji, Sacharz, Joanna, McConville, Calum, Moody, Edmund R. R., Shaw, Shrestha, Planelles-Herrero, Vicente J., Yadav, Sathish K. N., Ross, Jennifer, Borucu, Ufuk, Palmer, Catherine S., Chen, Kai-En, Croll, Tristan I., Hall, Ryan J., Caruana, Nikeisha J., Ghai, Rajesh, Nguyen, Thi H. D., Heesom, Kate J., Saitoh, Shinji, Berger, Imre, Schaffitzel, Christiane, Williams, Tom A., Stroud, David A., Derivery, Emmanuel, Collins, Brett M. and Cullen, Peter J. (2023). Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome. Cell, 186 (10), 2219-2237.e29. doi: 10.1016/j.cell.2023.04.003 |
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2023 Journal Article FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptorsNguyen‐Dien, Giang Thanh, Kozul, Keri‐Lyn, Cui, Yi, Townsend, Brendan, Kulkarni, Prajakta Gosavi, Ooi, Soo Siang, Marzio, Antonio, Carrodus, Nissa, Zuryn, Steven, Pagano, Michele, Parton, Robert G, Lazarou, Michael, Millard, S Sean, Taylor, Robert W, Collins, Brett M, Jones, Mathew JK and Pagan, Julia K (2023). FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors. The EMBO Journal, 42 (13) e112767, e112767. doi: 10.15252/embj.2022112767 |
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2023 Journal Article The association between inflammatory markers in blood and cerebrospinal fluid: a systematic review and meta-analysisGigase, Frederieke A. J., Smith, Emma, Collins, Brett, Moore, Kendall, Snijders, Gijsje J. L. J., Katz, Daniel, Bergink, Veerle, Perez-Rodriquez, M. Mercedes and De Witte, Lotje D. (2023). The association between inflammatory markers in blood and cerebrospinal fluid: a systematic review and meta-analysis. Molecular Psychiatry, 28 (4), 1502-1515. doi: 10.1038/s41380-023-01976-6 |
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2023 Journal Article Large 22q13.3 deletions perturb peripheral transcriptomic and metabolomic profiles in Phelan-McDermid syndromeBreen, Michael S., Fan, Xuanjia, Levy, Tess, Pollak, Rebecca M., Collins, Brett, Osman, Aya, Tocheva, Anna S., Sahin, Mustafa, Berry-Kravis, Elizabeth, Soorya, Latha, Thurm, Audrey, Powell, Craig M., Bernstein, Jonathan A., Kolevzon, Alexander and Buxbaum, Joseph D. (2023). Large 22q13.3 deletions perturb peripheral transcriptomic and metabolomic profiles in Phelan-McDermid syndrome. Human Genetics and Genomics Advances, 4 (1) 100145, 1-15. doi: 10.1016/j.xhgg.2022.100145 |
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2022 Conference Publication Peripheral and CSF inflammatory biomarkers after COVID-19 vaccination in pregnant individualsRajasekaran, Vignesh, Gigase, Frederieke, Smith, Emma, Collins, Brett, Katz, Daniel, Hamburger, Joshua, Ramirez-Zamudio, Andres, Janevic, Teresa, Spicer, Julie, Pietrzak, Robert, Jessel, Rebecca, Bergink, Veerle, Dolan, Siobhan M., McClure, Margaret, De Witte, Lotje and Perez-Rodriguez, M. Mercedes (2022). Peripheral and CSF inflammatory biomarkers after COVID-19 vaccination in pregnant individuals. 28th Annual Meeting of the PsychoNeuroImmunology-Research-Society, Zurich Switzerland, Jun 15-18, 2022. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. doi: 10.1016/j.bbi.2022.07.144 |
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2022 Journal Article Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteinsHealy, Michael D., Sacharz, Joanna, McNally, Kerrie E., McConville, Calum, Tillu, Vikas A., Hall, Ryan J., Chilton, Molly, Cullen, Peter J., Mobli, Mehdi, Ghai, Rajesh, Stroud, David A. and Collins, Brett M. (2022). Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins. Structure, 30 (12), 1590-1602.e6. doi: 10.1016/j.str.2022.10.001 |
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2022 Journal Article Rare coding variation provides insight into the genetic architecture and phenotypic context of autismFu, Jack M., Satterstrom, F. Kyle, Peng, Minshi, Brand, Harrison, Collins, Ryan L., Dong, Shan, Wamsley, Brie, Klei, Lambertus, Wang, Lily, Hao, Stephanie P., Stevens, Christine R., Cusick, Caroline, Babadi, Mehrtash, Banks, Eric, Collins, Brett, Dodge, Sheila, Gabriel, Stacey B., Gauthier, Laura, Lee, Samuel K., Liang, Lindsay, Ljungdahl, Alicia, Mahjani, Behrang, Sloofman, Laura, Smirnov, Andrey N., Barbosa, Mafalda, Betancur, Catalina, Brusco, Alfredo, Chung, Brian H. Y., Cook, Edwin H. ... Talkowski, Michael E. (2022). Rare coding variation provides insight into the genetic architecture and phenotypic context of autism. Nature Genetics, 54 (9), 1320-1334. doi: 10.1038/s41588-022-01104-0 |
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2022 Journal Article ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1Simonetti, Boris, Daly, James L., Simón-Gracia, Lorena, Klein, Katja, Weeratunga, Saroja, Antón-Plágaro, Carlos, Tobi, Allan, Hodgson, Lorna, Lewis, Philip A., Heesom, Kate J., Shoemark, Deborah K., Davidson, Andrew D., Collins, Brett M., Teesalu, Tambet, Yamauchi, Yohei and Cullen, Peter J. (2022). ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1. Proceedings of the National Academy of Sciences, 119 (25) e2201980119, 1-11. doi: 10.1073/pnas.2201980119 |
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2022 Journal Article The structure of caveolin finally takes shapeParton, Robert G. and Collins, Brett M. (2022). The structure of caveolin finally takes shape. Science Advances, 8 (19) eabq6985, eabq6985. doi: 10.1126/sciadv.abq6985 |
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2022 Journal Article SNX27–Retromer directly binds ESCPE-1 to transfer cargo proteins during endosomal recyclingSimonetti, Boris, Guo, Qian, Giménez-Andrés, Manuel, Chen, Kai-En, Moody, Edmund R. R., Evans, Ashley J., Chandra, Mintu, Danson, Chris M., Williams, Tom A., Collins, Brett M. and Cullen, Peter J. (2022). SNX27–Retromer directly binds ESCPE-1 to transfer cargo proteins during endosomal recycling. PLoS Biology, 20 (4) e3001601, e3001601. doi: 10.1371/journal.pbio.3001601 |
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2022 Journal Article Structural predictions of the SNX-RGS proteins suggest they belong to a new class of lipid transfer proteinsPaul, Blessy, Weeratunga, Saroja, Tillu, Vikas A., Hariri, Hanaa, Henne, W. Mike and Collins, Brett M. (2022). Structural predictions of the SNX-RGS proteins suggest they belong to a new class of lipid transfer proteins. Frontiers in Cell and Developmental Biology, 10 826688, 826688. doi: 10.3389/fcell.2022.826688 |
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2022 Journal Article Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation systemWu, Yue, Cui, Zhenling, Huang, Yen-Hua, de Veer, Simon J., Aralov, Andrey V., Guo, Zhong, Moradi, Shayli V., Hinton, Alexandra O., Deuis, Jennifer R., Guo, Shaodong, Chen, Kai-En, Collins, Brett M., Vetter, Irina, Herzig, Volker, Jones, Alun, Cooper, Matthew A., King, Glenn F., Craik, David J., Alexandrov, Kirill and Mureev, Sergey (2022). Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system. Nature Communications, 13 (1) 260, 260. doi: 10.1038/s41467-021-27854-9 |
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2022 Journal Article FGF1 and insulin control lipolysis by convergent pathwaysSancar, Gencer, Liu, Sihao, Gasser, Emanuel, Alvarez, Jacqueline G., Moutos, Christopher, Kim, Kyeongkyu, van Zutphen, Tim, Wang, Yuhao, Huddy, Timothy F., Ross, Brittany, Dai, Yang, Zepeda, David, Collins, Brett, Tilley, Emma, Kolar, Matthew J., Yu, Ruth T., Atkins, Annette R., van Dijk, Theo H., Saghatelian, Alan, Jonker, Johan W., Downes, Michael and Evans, Ronald M. (2022). FGF1 and insulin control lipolysis by convergent pathways. Cell Metabolism, 34 (1), 171-183. doi: 10.1016/j.cmet.2021.12.004 |
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2022 Journal Article Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminusChandra, Mintu, Collins, Brett M. and Jackson, Lauren P. (2022). Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminus. Advances in Biological Regulation, 83 100842, 1-9. doi: 10.1016/j.jbior.2021.100842 |
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2021 Journal Article De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complexChen, Kai-En, Guo, Qian, Hill, Timothy A., Cui, Yi, Kendall, Amy K., Yang, Zhe, Hall, Ryan J., Healy, Michael D., Sacharz, Joanna, Norwood, Suzanne J., Fonseka, Sachini, Xie, Boyang, Reid, Robert C., Leneva, Natalya, Parton, Robert G., Ghai, Rajesh, Stroud, David A., Fairlie, David P, Suga, Hiroaki, Jackson, Lauren P., Teasdale, Rohan D., Passioura, Toby and Collins, Brett M. (2021). De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. Science Advances, 7 (49) eabg4007, eabg4007. doi: 10.1126/sciadv.abg4007 |
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2021 Journal Article Rational design of potent peptide inhibitors of the PD-1:PD-L1 interaction for cancer immunotherapyYin, Huawu, Zhou, Xiuman, Huang, Yen-Hua, King, Gordon J., Collins, Brett M., Gao, Yanfeng, Craik, David J. and Wang, Conan K. (2021). Rational design of potent peptide inhibitors of the PD-1:PD-L1 interaction for cancer immunotherapy. Journal of the American Chemical Society, 143 (44) jacs.1c08132, 18536-18547. doi: 10.1021/jacs.1c08132 |
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2021 Journal Article Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscleLo, Harriet P., Lim, Ye-Wheen, Xiong, Zherui, Martel, Nick, Ferguson, Charles, Ariotti, Nicholas, Giacomotto, Jean, Rae, James, Floetenmeyer, Matthias, Moradi, Shayli Varasteh, Gao, Ya, Tillu, Vikas A., Xia, Di, Wang, Huang, Rahnama, Samira, Nixon, Susan J., Bastiani, Michele, Day, Ryan D., Smith, Kelly A., Palpant, Nathan J., Johnston, Wayne A., Alexandrov, Kirill, Collins, Brett M., Hall, Thomas E. and Parton, Robert G. (2021). Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle. Journal of Cell Biology, 220 (12) e201905065. doi: 10.1083/jcb.201905065 |
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2021 Journal Article Enabling efficient folding and high-resolution crystallographic analysis of bracelet cyclotidesHuang, Yen-Hua, Du, Qingdan, Jiang, Zhihao, King, Gordon J., Collins, Brett M., Wang, Conan K. and Craik, David J. (2021). Enabling efficient folding and high-resolution crystallographic analysis of bracelet cyclotides. Molecules, 26 (18) 5554, 5554. doi: 10.3390/molecules26185554 |
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2021 Journal Article Structural basis for the binding of the cancer targeting scorpion toxin, ClTx, to the vascular endothelia growth factor receptor neuropilin-1Sharma, Gagan, Braga, Carolyne B., Chen, Kai-En, Jia, Xinying, Ramanujam, Venkatraman, Collins, Brett M., Rittner, Roberto and Mobli, Mehdi (2021). Structural basis for the binding of the cancer targeting scorpion toxin, ClTx, to the vascular endothelia growth factor receptor neuropilin-1. Current Research in Structural Biology, 3, 179-186. doi: 10.1016/j.crstbi.2021.07.003 |
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2021 Journal Article Key phases in the formation of caveolaeParton, Robert G., Tillu, Vikas, McMahon, Kerrie-Ann and Collins, Brett M. (2021). Key phases in the formation of caveolae. Current Opinion in Cell Biology, 71, 7-14. doi: 10.1016/j.ceb.2021.01.009 |
