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2019 Journal Article Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord InjuryAlexander, Kylie A., Tseng, Hsu-Wen, Fleming, Whitney, Jose, Beulah, Salga, Marjorie, Kulina, Irina, Millard, Susan M., Pettit, Allison R., Genet, Francois and Levesque, Jean-Pierre (2019). Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury. Frontiers in Immunology, 10 (MAR) 377. doi: 10.3389/fimmu.2019.00377 |
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2019 Journal Article Blocking neuromuscular junctions with botulinum toxin A injection enhances neurological heterotopic ossification development after spinal cord injury in miceSalga, Marjorie, Tseng, Hsu-Wen, Alexander, Kylie A., Jose, Beulah, Vaquette, Cedryck, Debaud, Charlotte, Gatin, Laure, Genêt, François and Levesque, Jean-Pierre (2019). Blocking neuromuscular junctions with botulinum toxin A injection enhances neurological heterotopic ossification development after spinal cord injury in mice. Annals of Physical and Rehabilitation Medicine, 62 (3), 189-192. doi: 10.1016/j.rehab.2019.01.005 |
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2018 Conference Publication Oncostatin M is a key effector of heterotopic ossification following spinal cord injuriesTseng, Hsu-Wen, Alexander, Kylie, Kulina, Irina, Salga, Marjorie, Jose, Beulah, Genet, Francois, Torossian, Frederic, Guerton, Bernadette, Anginot, Adrienne, Fleming, Whitney, Millard, Susan, Pettit, Allison, Sims, Natalie, Lataillade, Jean-Jacques, Le Bousse-Kerdiles, Marie-Caroline and Levesque, Jean Pierre (2018). Oncostatin M is a key effector of heterotopic ossification following spinal cord injuries. Annual Meeting of the American Society for Bone and Mineral Research, Montreal Canada, September 28 - October 1 2018. Hoboken, NJ United States: Wiley. |
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2017 Journal Article Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven MechanismsLevesque, Jean-Pierre, Sims, Natalie A., Pettit, Allison R., Alexander, Kylie A., Tseng, Hsu-Wen, Torossian, Frédéric, Genêt, François, Lataillade, Jean-Jacques and Le Bousse-Kerdilès, Marie-Caroline (2017). Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven Mechanisms. Journal of Bone and Mineral Research, 33 (2), 365-366. doi: 10.1002/jbmr.3346 |
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2017 Journal Article Macrophage-derived oncostatin M contributes to human and mouse neurogenic heterotopic ossificationsTorossian, Frédéric, Guerton, Bernadette, Anginot, Adrienne, Alexander, Kylie A., Desterke, Christophe , Soave, Sabrina, Tseng, Hsu-Wen, Arouche, Nassim, Boutin, Laetitia, Kulina, Irina, Salga, Marjorie, Jose, Beulah, Pettit, Allison R., Clay, Denis, Rochet, Nathalie, Vlachos, Erica, Genet, Guillaume, Debaud, Charlotte, Denormandie, Philippe, Genet, François, Sims, Natalie A., Banzet, Sébastien, Levesque, Jean-Pierre, Lataillade, Jean-Jacques and Le Bousse-Kerdilès, Marie-Caroline (2017). Macrophage-derived oncostatin M contributes to human and mouse neurogenic heterotopic ossifications. JCI Insight, 2 (21) e96034. doi: 10.1172/jci.insight.96034 |
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2017 Journal Article Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-beta productionDu, Jing, Paz, Katelyn, Flynn, Ryan, Vulic, Ante, Robinson, Tara M., Lineburg, Katie E., Alexander, Kylie A., Meng, Jingjing, Roy, Sabita, Panoskaltsis-Mortari, Angela, Loschi, Michael, Hill, Geoffrey R., Serody, Jonathan S., Maillard, Ivan, Miklos, David, Koreth, John, Cutler, Corey S., Antin, Joseph H., Ritz, Jerome, MacDonald, Kelli P., Schacker, Timothy W., Luznik, Leo and Blazar, Bruce R. (2017). Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-beta production. Blood, 129 (18), 2570-2580. doi: 10.1182/blood-2017-01-758854 |
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2016 Journal Article Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host diseaseLe Texier, Laetitia, Lineburg, Katie E., Cao, Benjamin, McDonald-Hyman, Cameron, Leveque-El Mouttie, Lucie, Nicholls, Jemma, Melino, Michelle, Nalkurthi, Blessy C., Alexander, Kylie A., Teal, Bianca, Blake, Stephen J., Souza-Fonseca-Guimaraes, Fernando, Engwerda, Christian R., Kuns, Rachel D., Lane, Steven W., Teng, Michele, Teh, Charis, Gray, Daniel, Clouston, Andrew D., Nilsson, Susan K., Blazar, Bruce R., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2016). Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease. JCI Insight, 1 (15) e86850, e86850. doi: 10.1172/jci.insight.86850 |
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2016 Journal Article Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regenerationAlexander, Kylie Anne, Raggatt, Liza-Jane, Millard, Susan, Batoon, Lena, Wu, Andy Chiu-Ku, Chang, Ming-Kang, Hume, David Arthur and Pettit, Allison Robyn (2016). Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration. Immunology and Cell Biology, 95 (1), 7-16. doi: 10.1038/icb.2016.74 |
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2016 Journal Article Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHDLeveque-El Mouttie, Lucie, Koyama, Motoko, Le Texier, Laetitia, Markey, Kate A., Cheong, Melody, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Alexander, Kylie A., Clouston, Andrew D., Blazar, Bruce R., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2016). Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD. Blood, 128 (6), 794-804. doi: 10.1182/blood-2015-11-680876 |
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2016 Conference Publication Autophagy-dependent TIGIT+ Treg are critical for the maintenance of toleranceMacDonald, Kelli P. A., Le Texier, Laetitia, Leveque-ElMouttie, Lucie, Lineburg, Katie, Nicholls, Jemma, Guimaraes, Fernando Souza-Fonseca, Alexander, Kylie, Clouston, Andrew, Blazar, Bruce R. and Hill, Geoff R. (2016). Autophagy-dependent TIGIT+ Treg are critical for the maintenance of tolerance. Immunology 2016 Meeting, Seattle, WA United States, 13-17 May 2016. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.196.supp.125.14 |
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2016 Journal Article Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury modelMelino, Michelle, Gadd, Victoria L., Alexander, Kylie A., Beattie, Lynette, Lineburg, Katie E., Martinez, Michelle, Teal, Bianca, Le Texier, Laetitia, Irvine, Katharine M., Miller, Gregory C., Boyle, Glen M., Hill, Geoffrey R., Clouston, Andrew D., Powel, Elizabeth E. and MacDonald, Kelli P. A. (2016). Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model. American Journal of Pathology, 186 (3), 524-538. doi: 10.1016/j.ajpath.2015.10.029 |
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2015 Journal Article Targeting Syk-activated B cells in murine and human chronic graft-versus-host diseaseFlynn, Ryan, Allen, Jessica L., Luznik, Leo, MacDonald, Kelli P., Paz, Katelyn, Alexander, Kylie A., Vulic, Ante, Du, Jing, Panoskaltsis-Mortari, Angela, Taylor, Patricia A., Poe, Jonathan C., Serody, Jonathan S., Murphy, William J., Hill, Geoffrey R., Maillard, Ivan, Koreth, John, Cutler, Corey S., Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Chao, Nelson J., Clynes, Raphael A., Sarantopoulos, Stefanie and Blazar, Bruce R. (2015). Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease. Blood, 125 (26), 4085-4094. doi: 10.1182/blood-2014-08-595470 |
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2015 Journal Article Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantationVarelias, Antiopi, Gartlan, Kate H., Kreijveld, Ellen, Olver, Stuart D., Lor, Mary, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Raffelt, Neil C., Cheong, Melody, Alexander, Kylie A., Koyama, Motoko, Markey, Kate A., Sturgeon, Elise, Leach, Justine, Reddy, Pavan, Kennedy, Glen A., Yanik, Gregory A., Blazar, Bruce R., Tey, Siok-Keen, Clouston, Andrew D., MacDonald, Kelli P. A., Cooke, Kenneth R. and Hill, Geoffrey R. (2015). Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation. Blood, 125 (15), 2435-2444. doi: 10.1182/blood-2014-07-590232 |
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2015 Conference Publication Autophagy-Dependent Tigit Positive Helios Positive Regulatory T Cells Are Critical for Controlling Gvhd After Allogeneic Stem Cell TransplantationLe Texier, Laetitia, Leveque-ElMouttie, Lucie, Lineburg, Katie E., Alexander, Kylie A., Melino, Michelle, Teal, Bianca, Martinez, Michelle, Kuns, Rachel D., Lane, Steven W., Engwerda, Christian, Blazar, Bruce R., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2015). Autophagy-Dependent Tigit Positive Helios Positive Regulatory T Cells Are Critical for Controlling Gvhd After Allogeneic Stem Cell Transplantation. 14th Transplantation Science Symposium of the Transplantation-Society (TSS), Lorne, VIC, Australia, 11-13 November 2015. Philadelphia, PA, United States: Lippincott Williams & Wilkins. |
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2014 Journal Article Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossificationRaggatt, Liza J., Wullschleger, Martin E., Alexander, Kylie A., Wu, Andy C. K., Millard, Susan M., Kaur, Simranpreet, Maugham, Michelle L., Gregory, Laura S., Steck, Roland and Pettit, Allison R. (2014). Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification. American Journal of Pathology, 184 (12), 3192-3204. doi: 10.1016/j.ajpath.2014.08.017 |
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2014 Conference Publication Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantationVarelias, Antiopi, Gartlan, Kate H., Kreijveld, Ellen, Olver, Stuart D., Lor, Mary, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Raffelt, Neil C., Cheong, Melody, Alexander, Kylie A., Koyama, Motoko, Markey, Kate A., Sturgeon, Elise, Leach, Justine, Reddy, Pavan, Kennedy, Glen, Yanik, Gregory, Blazar, Bruce R., Tey, Siok K., Clouston, Andrew, MacDonald, Kelli P. A., Cooke, Kenneth R. and Hill, Geoffrey R. (2014). Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne, Australia, 26-29 October 2014. London, United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.195 |
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2014 Journal Article CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host diseaseAlexander K.A., Flynn R., Lineburg K.E., Kuns R.D., Teal B.E., Olver S.D., Lor M., Raffelt N.C., Koyama M., Leveque L., Le Texier L., Melino M., Markey K.A., Varelias A., Engwerda C., Serody J.S., Janela B., Ginhoux F., Clouston A.D., Blazar B.R., Hill G.R. and MacDonald K.P.A. (2014). CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease. Journal of Clinical Investigation, 124 (10), 4266-4280. doi: 10.1172/JCI75935 |
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2014 Conference Publication CSF-1-dependant M2 macrophages mediate chronic graft-versus-host diseaseAlexander, K., Flynn, R., Lineburg, K., Kuns, R., Janela, B., Teal, B., Olver, S., Lor, M., Raffelt, N., Koyama, M., Leveque, L., Le Texier, L., Melino, M., Markey, K., Varelias, A., Ginhoux, F., Engwerda, C., Clouston, A., Blazer, B., Hill, G. and MacDonald, K. (2014). CSF-1-dependant M2 macrophages mediate chronic graft-versus-host disease. World Transplant Congress, San Francisco, CA, United States, 26-31 July 2014. Hoboken, NJ, United States: Wiley-Blackwell. |
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2014 Conference Publication CSF-1-Dependant M2 Macrophages Mediate Chronic Graft-Versus-Host DiseaseAlexander, K., Flynn, R., Lineburg, K., Kuns, R., Janela, B., Teal, B., Olver, S., Lor, M., Raffelt, N., Koyama, M., Leveque, L., Le Texier, L., Melino, M., Markey, K., Varelias, A., Ginhoux, F., Engwerda, C., Clouston, A., Blazer, B., Hill, G. and MacDonald, K. (2014). CSF-1-Dependant M2 Macrophages Mediate Chronic Graft-Versus-Host Disease. World Transplant Congress, San Francisco United States, Jul 26-31, 2014. Philadelphia United States: Lippincott Williams & Wilkins. doi: 10.1097/01.tp.0000452130.27963.71 |
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2013 Journal Article Activated human T cells express alternative mRNA transcripts encoding a secreted form of RANKLWalsh, N. C., Alexander, K. A., Manning, C. A., Karmakar, S. K., Wang, J. F., Weyand, C. M., Pettit, A. R. and Gravallese, E. M. (2013). Activated human T cells express alternative mRNA transcripts encoding a secreted form of RANKL. Genes and Immunity, 14 (5), 336-345. doi: 10.1038/gene.2013.29 |
