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2017 Journal Article Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-beta productionDu, Jing, Paz, Katelyn, Flynn, Ryan, Vulic, Ante, Robinson, Tara M., Lineburg, Katie E., Alexander, Kylie A., Meng, Jingjing, Roy, Sabita, Panoskaltsis-Mortari, Angela, Loschi, Michael, Hill, Geoffrey R., Serody, Jonathan S., Maillard, Ivan, Miklos, David, Koreth, John, Cutler, Corey S., Antin, Joseph H., Ritz, Jerome, MacDonald, Kelli P., Schacker, Timothy W., Luznik, Leo and Blazar, Bruce R. (2017). Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-beta production. Blood, 129 (18), 2570-2580. doi: 10.1182/blood-2017-01-758854 |
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2016 Journal Article Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host diseaseLe Texier, Laetitia, Lineburg, Katie E., Cao, Benjamin, McDonald-Hyman, Cameron, Leveque-El Mouttie, Lucie, Nicholls, Jemma, Melino, Michelle, Nalkurthi, Blessy C., Alexander, Kylie A., Teal, Bianca, Blake, Stephen J., Souza-Fonseca-Guimaraes, Fernando, Engwerda, Christian R., Kuns, Rachel D., Lane, Steven W., Teng, Michele, Teh, Charis, Gray, Daniel, Clouston, Andrew D., Nilsson, Susan K., Blazar, Bruce R., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2016). Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease. JCI Insight, 1 (15) e86850, e86850. doi: 10.1172/jci.insight.86850 |
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2016 Journal Article Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regenerationAlexander, Kylie Anne, Raggatt, Liza-Jane, Millard, Susan, Batoon, Lena, Wu, Andy Chiu-Ku, Chang, Ming-Kang, Hume, David Arthur and Pettit, Allison Robyn (2016). Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration. Immunology and Cell Biology, 95 (1), 7-16. doi: 10.1038/icb.2016.74 |
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2016 Journal Article Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHDLeveque-El Mouttie, Lucie, Koyama, Motoko, Le Texier, Laetitia, Markey, Kate A., Cheong, Melody, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Alexander, Kylie A., Clouston, Andrew D., Blazar, Bruce R., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2016). Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD. Blood, 128 (6), 794-804. doi: 10.1182/blood-2015-11-680876 |
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2016 Conference Publication Autophagy-dependent TIGIT+ Treg are critical for the maintenance of toleranceMacDonald, Kelli P. A., Le Texier, Laetitia, Leveque-ElMouttie, Lucie, Lineburg, Katie, Nicholls, Jemma, Guimaraes, Fernando Souza-Fonseca, Alexander, Kylie, Clouston, Andrew, Blazar, Bruce R. and Hill, Geoff R. (2016). Autophagy-dependent TIGIT+ Treg are critical for the maintenance of tolerance. Immunology 2016 Meeting, Seattle, WA United States, 13-17 May 2016. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.196.supp.125.14 |
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2016 Journal Article Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury modelMelino, Michelle, Gadd, Victoria L., Alexander, Kylie A., Beattie, Lynette, Lineburg, Katie E., Martinez, Michelle, Teal, Bianca, Le Texier, Laetitia, Irvine, Katharine M., Miller, Gregory C., Boyle, Glen M., Hill, Geoffrey R., Clouston, Andrew D., Powel, Elizabeth E. and MacDonald, Kelli P. A. (2016). Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model. American Journal of Pathology, 186 (3), 524-538. doi: 10.1016/j.ajpath.2015.10.029 |
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2015 Journal Article Targeting Syk-activated B cells in murine and human chronic graft-versus-host diseaseFlynn, Ryan, Allen, Jessica L., Luznik, Leo, MacDonald, Kelli P., Paz, Katelyn, Alexander, Kylie A., Vulic, Ante, Du, Jing, Panoskaltsis-Mortari, Angela, Taylor, Patricia A., Poe, Jonathan C., Serody, Jonathan S., Murphy, William J., Hill, Geoffrey R., Maillard, Ivan, Koreth, John, Cutler, Corey S., Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Chao, Nelson J., Clynes, Raphael A., Sarantopoulos, Stefanie and Blazar, Bruce R. (2015). Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease. Blood, 125 (26), 4085-4094. doi: 10.1182/blood-2014-08-595470 |
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2015 Journal Article Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantationVarelias, Antiopi, Gartlan, Kate H., Kreijveld, Ellen, Olver, Stuart D., Lor, Mary, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Raffelt, Neil C., Cheong, Melody, Alexander, Kylie A., Koyama, Motoko, Markey, Kate A., Sturgeon, Elise, Leach, Justine, Reddy, Pavan, Kennedy, Glen A., Yanik, Gregory A., Blazar, Bruce R., Tey, Siok-Keen, Clouston, Andrew D., MacDonald, Kelli P. A., Cooke, Kenneth R. and Hill, Geoffrey R. (2015). Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation. Blood, 125 (15), 2435-2444. doi: 10.1182/blood-2014-07-590232 |
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2015 Conference Publication Autophagy-Dependent Tigit Positive Helios Positive Regulatory T Cells Are Critical for Controlling Gvhd After Allogeneic Stem Cell TransplantationLe Texier, Laetitia, Leveque-ElMouttie, Lucie, Lineburg, Katie E., Alexander, Kylie A., Melino, Michelle, Teal, Bianca, Martinez, Michelle, Kuns, Rachel D., Lane, Steven W., Engwerda, Christian, Blazar, Bruce R., Hill, Geoffrey R. and MacDonald, Kelli P. A. (2015). Autophagy-Dependent Tigit Positive Helios Positive Regulatory T Cells Are Critical for Controlling Gvhd After Allogeneic Stem Cell Transplantation. 14th Transplantation Science Symposium of the Transplantation-Society (TSS), Lorne, VIC, Australia, 11-13 November 2015. Philadelphia, PA, United States: Lippincott Williams & Wilkins. |
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2014 Journal Article Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossificationRaggatt, Liza J., Wullschleger, Martin E., Alexander, Kylie A., Wu, Andy C. K., Millard, Susan M., Kaur, Simranpreet, Maugham, Michelle L., Gregory, Laura S., Steck, Roland and Pettit, Allison R. (2014). Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification. American Journal of Pathology, 184 (12), 3192-3204. doi: 10.1016/j.ajpath.2014.08.017 |
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2014 Conference Publication Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantationVarelias, Antiopi, Gartlan, Kate H., Kreijveld, Ellen, Olver, Stuart D., Lor, Mary, Kuns, Rachel D., Lineburg, Katie E., Teal, Bianca E., Raffelt, Neil C., Cheong, Melody, Alexander, Kylie A., Koyama, Motoko, Markey, Kate A., Sturgeon, Elise, Leach, Justine, Reddy, Pavan, Kennedy, Glen, Yanik, Gregory, Blazar, Bruce R., Tey, Siok K., Clouston, Andrew, MacDonald, Kelli P. A., Cooke, Kenneth R. and Hill, Geoffrey R. (2014). Lung parenchyma-derived IL-6 promotes IL-17A-dependent acute lung injury after allogeneic stem cell transplantation. 2nd Annual Meeting of the International-Cytokine-and-Interferon-Society (ICIS), Melbourne, Australia, 26-29 October 2014. London, United Kingdom: Academic Press. doi: 10.1016/j.cyto.2014.07.195 |
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2014 Journal Article CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host diseaseAlexander K.A., Flynn R., Lineburg K.E., Kuns R.D., Teal B.E., Olver S.D., Lor M., Raffelt N.C., Koyama M., Leveque L., Le Texier L., Melino M., Markey K.A., Varelias A., Engwerda C., Serody J.S., Janela B., Ginhoux F., Clouston A.D., Blazar B.R., Hill G.R. and MacDonald K.P.A. (2014). CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease. Journal of Clinical Investigation, 124 (10), 4266-4280. doi: 10.1172/JCI75935 |
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2014 Conference Publication CSF-1-dependant M2 macrophages mediate chronic graft-versus-host diseaseAlexander, K., Flynn, R., Lineburg, K., Kuns, R., Janela, B., Teal, B., Olver, S., Lor, M., Raffelt, N., Koyama, M., Leveque, L., Le Texier, L., Melino, M., Markey, K., Varelias, A., Ginhoux, F., Engwerda, C., Clouston, A., Blazer, B., Hill, G. and MacDonald, K. (2014). CSF-1-dependant M2 macrophages mediate chronic graft-versus-host disease. World Transplant Congress, San Francisco, CA, United States, 26-31 July 2014. Hoboken, NJ, United States: Wiley-Blackwell. |
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2014 Conference Publication CSF-1-Dependant M2 Macrophages Mediate Chronic Graft-Versus-Host DiseaseAlexander, K., Flynn, R., Lineburg, K., Kuns, R., Janela, B., Teal, B., Olver, S., Lor, M., Raffelt, N., Koyama, M., Leveque, L., Le Texier, L., Melino, M., Markey, K., Varelias, A., Ginhoux, F., Engwerda, C., Clouston, A., Blazer, B., Hill, G. and MacDonald, K. (2014). CSF-1-Dependant M2 Macrophages Mediate Chronic Graft-Versus-Host Disease. World Transplant Congress, San Francisco United States, Jul 26-31, 2014. Philadelphia United States: Lippincott Williams & Wilkins. doi: 10.1097/01.tp.0000452130.27963.71 |
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2013 Journal Article Activated human T cells express alternative mRNA transcripts encoding a secreted form of RANKLWalsh, N. C., Alexander, K. A., Manning, C. A., Karmakar, S. K., Wang, J. F., Weyand, C. M., Pettit, A. R. and Gravallese, E. M. (2013). Activated human T cells express alternative mRNA transcripts encoding a secreted form of RANKL. Genes and Immunity, 14 (5), 336-345. doi: 10.1038/gene.2013.29 |
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2013 Journal Article Unraveling macrophage contributions to bone repairWu, Andy C., Raggatt, Liza J., Alexander, Kylie A. and Pettit, Allison R. (2013). Unraveling macrophage contributions to bone repair. BoneKEy Reports, 2 (373), 1-1. doi: 10.1038/bonekey.2013.107 |
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2013 Journal Article Absence of B cells does Not compromise intramembranous bone formation during healing in a tibial injury modelRaggatt, Liza J., Alexander, Kylie A., Kaur, Simranpreet, Wu, Andy C., MacDonald, Kelli P. A. and Pettit, Allison R. (2013). Absence of B cells does Not compromise intramembranous bone formation during healing in a tibial injury model. American Journal of Pathology, 182 (5), 1501-1508. doi: 10.1016/j.ajpath.2013.01.046 |
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2013 Journal Article Promoting regulation via the inhibition of DNAM-1 after transplantationKoyama, Motoko, Kuns, Rachel D., Olver, Stuart D., Lineburg, Katie E., Lor, Mary, Teal, Bianca E., Raffelt, Neil C., Leveque, Lucie, Chan, Christopher J., Robb, Renee J., Markey, Kate A., Alexander, Kylie A., Varelias, Antiopi, Clouston, Andrew D., Smyth, Mark J., MacDonald, Kelli P.A. and Hill, Geoffrey R. (2013). Promoting regulation via the inhibition of DNAM-1 after transplantation. Blood, 121 (17), 3511-3520. doi: 10.1182/blood-2012-07-444026 |
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2013 Conference Publication Fracture Healing Via Periosteal Callus Formation Requires Macrophages for Both Initiation and Progression of Endochondral OssificationPettit, A., Raggatt, L., Wullschleger, M., Alexander, K., Steck, R., Kaur, S. and Wu, A. (2013). Fracture Healing Via Periosteal Callus Formation Requires Macrophages for Both Initiation and Progression of Endochondral Ossification. Annual Meeting of the American Society for Bone and Mineral Research, Baltimore MD United States, 4-7 October 2013. Hoboken, NJ United States: Wiley-Blackwell. |
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2013 Conference Publication Lung Parenchyma-Derived IL-6 Induces Alloantigen Specific Th17 Differentiation Within The Lung and Idiopathic Pneumonia Syndrome After Allogeneic Stem Cell TransplantationVarelias, Antiopi, Gartlan, Kate H., Olver, Stuart D., Lineburg, Katie E., Kuns, Rachel D., Lor, Mary, Teal, Bianca E., Cheong, Melody, Koyama, Motoko, Markey, Kate A., Alexander, Kylie, Budelsky, Alison, Sturgeon, Elise, Leach, Justine, Avery, Judy, Kennedy, Glen A., Siok-Tey, Clouston, Andrew D., MacDonald, Kelli P. A. and Hill, Geoff R. (2013). Lung Parenchyma-Derived IL-6 Induces Alloantigen Specific Th17 Differentiation Within The Lung and Idiopathic Pneumonia Syndrome After Allogeneic Stem Cell Transplantation. 55th Annual Meeting of the American Society of Hematology, New Orleans, LA United States, 7-10 December 2013. Washington, DC United States: American Society of Hematology. |
