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2018

Journal Article

Ultrastructural localisation of protein interactions using conditionally stable nanobodies

Ariotti, Nicholas, Rae, James, Giles, Nichole, Martel, Nick, Sierecki, Emma, Gambin, Yann, Hall, Thomas E. and Parton, Robert G. (2018). Ultrastructural localisation of protein interactions using conditionally stable nanobodies. PLoS Biology, 16 (4) e2005473, e2005473. doi: 10.1371/journal.pbio.2005473

Ultrastructural localisation of protein interactions using conditionally stable nanobodies

2018

Journal Article

PH-responsive morphology-controlled redox behavior and cellular uptake of nanoceria in fibrosarcoma

Mehmood, Rashid, Ariotti, Nicholas, Yang, Jia Lin, Koshy, Pramod and Sorrell, Charles C. (2018). PH-responsive morphology-controlled redox behavior and cellular uptake of nanoceria in fibrosarcoma. ACS Biomaterials Science and Engineering, 4 (3), 1064-1072. doi: 10.1021/acsbiomaterials.7b00806

PH-responsive morphology-controlled redox behavior and cellular uptake of nanoceria in fibrosarcoma

2018

Journal Article

Real-time synchrotron small-angle x-ray scattering studies of collagen structure during leather processing

Zhang, Yi, Ingham, Bridget, Cheong, Soshan, Ariotti, Nicholas, Tilley, Richard D., Naffa, Rafea, Holmes, Geoff, Clarke, David J. and Prabakar, Sujay (2018). Real-time synchrotron small-angle x-ray scattering studies of collagen structure during leather processing. Industrial and Engineering Chemistry Research, 57 (1), 63-69. doi: 10.1021/acs.iecr.7b03860

Real-time synchrotron small-angle x-ray scattering studies of collagen structure during leather processing

2017

Journal Article

Journey to the centre of the cell: Virtual reality immersion into scientific data

Johnston, Angus P. R., Rae, James, Ariotti, Nicholas, Bailey, Benjamin, Lija, Andrew, Webb, Robyn, Ferguson, Charles, Maher, Sheryl, Davis, Thomas P., Webb, Richard I., McGhee, John and Parton, Robert G. (2017). Journey to the centre of the cell: Virtual reality immersion into scientific data. Traffic (Copenhagen, Denmark), 19 (2), 105-110. doi: 10.1111/tra.12538

Journey to the centre of the cell: Virtual reality immersion into scientific data

2017

Journal Article

Correlative light and electron microscopic detection of GFP-labeled proteins using modular APEX

Ariotti, Nicholas, Hall, Thomas E. and Parton, Robert G. (2017). Correlative light and electron microscopic detection of GFP-labeled proteins using modular APEX. Methods in Cell Biology, 140, 105-121. doi: 10.1016/bs.mcb.2017.03.002

Correlative light and electron microscopic detection of GFP-labeled proteins using modular APEX

2016

Journal Article

Nanomolar oligomerization and selective co-aggregation of α-synuclein pathogenic mutants revealed by single-molecule fluorescence

Sierecki, Emma, Giles, Nichole, Bowden, Quill, Polinkovsky, Mark E., Steinbeck, Janina, Arrioti, Nicholas, Rahman, Diya, Bhumkar, Akshay, Nicovich, Philip R., Ross, Ian, Parton, Robert G., Bocking, Till and Gambin, Yann (2016). Nanomolar oligomerization and selective co-aggregation of α-synuclein pathogenic mutants revealed by single-molecule fluorescence. Scientific Reports, 6 (1) 37630, 37630. doi: 10.1038/srep37630

Nanomolar oligomerization and selective co-aggregation of α-synuclein pathogenic mutants revealed by single-molecule fluorescence

2016

Journal Article

Parkinson disease-linked Vps35 R524W mutation impairs the endosomal association of retromer and induces α-synuclein aggregation

Follett, Jordan, Bugarcic, Andrea, Yang, Zhe, Ariotti, Nicholas, Norwood, Suzanne J., Collins, Brett M., Parton, Robert G. and Teasdale, Rohan D. (2016). Parkinson disease-linked Vps35 R524W mutation impairs the endosomal association of retromer and induces α-synuclein aggregation. Journal of Biological Chemistry, 291 (35), 18283-18298. doi: 10.1074/jbc.M115.703157

Parkinson disease-linked Vps35 R524W mutation impairs the endosomal association of retromer and induces α-synuclein aggregation

2016

Journal Article

New transgenic lines for localization of GFP-tagged proteins by electron microscope

Hall, Thomas, Ariotti, Nicholas, Ferguson, Charles, Zherui, Xiong and Parton, Robert G. (2016). New transgenic lines for localization of GFP-tagged proteins by electron microscope. Zebrafish, 13 (3), 232-233. doi: 10.1089/zeb.2016.29002.hal

New transgenic lines for localization of GFP-tagged proteins by electron microscope

2016

Journal Article

Galectin-1 dimers can scaffold Raf-effectors to increase H-ras nanoclustering

Blazevits, Olga, Mideksa, Yonatan G., Solman, Maja, Ligabue, Alessio, Ariotti, Nicholas, Nakhaeizadeh, Hossein, Fansa, Eyad K., Papageorgiou, Anastassios C., Wittinghofer, Alfred, Ahmadian, Mohammad R. and Abankwa, Daniel (2016). Galectin-1 dimers can scaffold Raf-effectors to increase H-ras nanoclustering. Scientific Reports, 6 (1) 24165, 24165. doi: 10.1038/srep24165

Galectin-1 dimers can scaffold Raf-effectors to increase H-ras nanoclustering

2016

Conference Publication

Redefining caveolae as signalling platforms: specificity of interactions on endocytic caveolae in response to stress

Gambin, Yann, Sierecki, Emma, Jung, WooRam, Ariotti, Nicholas, Giles, Nichole, Bastiani, Michele and Parton, Robert (2016). Redefining caveolae as signalling platforms: specificity of interactions on endocytic caveolae in response to stress. Experimental Biology 2016 Meeting, San Diego, CA United States, 1-5 April 2016. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.30.1_supplement.879.2

Redefining caveolae as signalling platforms: specificity of interactions on endocytic caveolae in response to stress

2016

Conference Publication

Journey to the centre of the cell (JTCC)∗: a 3D VR experience derived from migratory breast cancer cell image data

McGhee, John, Bailey, Benjamin, Parton, Robert G., Ariotti, Nicholas and Johnston, Angus (2016). Journey to the centre of the cell (JTCC)∗: a 3D VR experience derived from migratory breast cancer cell image data. 2016 SIGGRAPH ASIA VR Showcase, SA 2016, Macau, China, 5 - 8 December 2016. New York, NY, United States: Association for Computing Machinery. doi: 10.1145/2996376.2996385

Journey to the centre of the cell (JTCC)∗: a 3D VR experience derived from migratory breast cancer cell image data

2015

Journal Article

Modular detection of GFP-labeled proteins for rapid screening by electron microscopy in cells and organisms

Ariotti, Nicholas, Hall, Thomas, Rae, James, Ferguson, Charles, McMahon, Kerrie-Ann, Martel, Nick, Webb, Robyn E., Webb, Richard I., Teasdale, Rohan D. and Parton, Robert G. (2015). Modular detection of GFP-labeled proteins for rapid screening by electron microscopy in cells and organisms. Developmental Cell, 35 (4), 513-525. doi: 10.1016/j.devcel.2015.10.016

Modular detection of GFP-labeled proteins for rapid screening by electron microscopy in cells and organisms

2015

Journal Article

Molecular characterization of caveolin-induced membrane curvature

Ariotti, Nicholas, Rae, James, Leneva, Natalya, Ferguson, Charles, Loo, Dorothy, Okano, Satomi, Hill, Michelle M., Walser, Piers, Collins, Brett M. and Parton, Robert G. (2015). Molecular characterization of caveolin-induced membrane curvature. Journal of Biological Chemistry, 290 (41), 24875-24890. doi: 10.1074/jbc.M115.644336

Molecular characterization of caveolin-induced membrane curvature

2015

Journal Article

Cavin family proteins and the assembly of caveolae

Kovtun, Oleksiy, Tillu, Vikas A., Ariotti, Nicholas, Parton, Robert G. and Collins, Brett M. (2015). Cavin family proteins and the assembly of caveolae. Journal of Cell Science, 128 (7), 1269-1278. doi: 10.1242/jcs.167866

Cavin family proteins and the assembly of caveolae

2014

Journal Article

Structural insights into the organization of the cavin membrane coat complex

Kovtun, Oleksiy, Tilu, Vikas A., Jung, WooRam, Leneva, Natalya, Ariotti, Nicholas, Chaudhary, Natasha, Mandyam, Ramya A., Ferguson, Charles, Morgan, Garry P., Johnston, Wayne A., Harrop, Stephen J., Alexandrov, Kirill, Parton, Robert G. and Collins, Brett M. (2014). Structural insights into the organization of the cavin membrane coat complex. Developmental Cell, 31 (4), 405-419. doi: 10.1016/j.devcel.2014.10.002

Structural insights into the organization of the cavin membrane coat complex

2014

Conference Publication

Structural dissection of architecture of caveolar protein coat

Kovtun, O., Tillu, V., Jung, W., Leneva, N., Ariotti, N., Alexandrov, K., Parton, R. and Collins, B. (2014). Structural dissection of architecture of caveolar protein coat. FEBS EMBO 2014 Conference, Paris, France, 30 August - 4 September, 2014. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

Structural dissection of architecture of caveolar protein coat

2014

Journal Article

Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling

Ariotti, Nicholas, Fernández-Rojo, Manuel, Zhou, Yong, Hill, Michelle M., Rodkey, Travis L., Inder, Kerry L., Tanner, Lukas B., Wenk, Markus R., Hancock, John F. and Parton, Robert G. (2014). Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling. Journal of Cell Biology, 204 (5), 777-792. doi: 10.1083/jcb.201307055

Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling

2014

Journal Article

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae

Gambin, Yann, Ariotti, Nicholas, McMahon, Kerrie-Ann, Bastiani, Michele, Sierecki, Emma, Kovtun, Oleksiy, Polinkovsky, Mark E., Magenau, Astrid, Jung, WooRam, Okano, Satomi, Zhou, Yong, Leneva, Natalya, Mureev, Sergey, Johnston, Wayne, Gaus, Katharina, Hancock, John F., Collins, Brett M., Alexandrov, Kirill and Parton, Robert G. (2014). Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae. eLIFE, 2014 (3) e01434, e01434.1-e01434.18. doi: 10.7554/eLife.01434

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae

2014

Journal Article

Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers

Lakshminarayan, Ramya, Wunder, Christian, Becken, Ulrike, Howes, Mark T., Benzing, Carola, Arumugam, Senthil, Sales, Susanne, Ariotti, Nicholas, Chambon, Valérie, Lamaze, Christophe, Loew, Damarys, Shevchenko, Andrej, Gaus, Katharina, Parton, Robert G. and Johannes, Ludger (2014). Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers. Nature Cell Biology, 16 (6), 592-603. doi: 10.1038/ncb2970

Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers

2013

Journal Article

Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters

Zhou, Yong, Liang, Hong, Rodkey, Travis, Ariotti, Nicholas, Parton, Robert G. and Hancock, John F. (2013). Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters. Molecular and Cellular Biology, 34 (5), 862-876. doi: 10.1128/MCB.01227-13

Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters