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2025 Journal Article Meropenem dosing optimization on day 1 and steady state in critically ill patients without significant renal impairmentSulaiman, Helmi, Rozali, Muhammad Azrai, Adiraju, Santosh K. S., Hasan, M. Shahnaz, Jamal, Janattul A., Liu, Xin, Mat-Nor, Mohd-Basri, Mazlan, Mohd Zulfakar, Othman-Jailani, Mohamad Irfan, Salmuna, Zeti Norfidiyati, Wallis, Steven C., Roberts, Jason A. and Abdul-Aziz, Mohd H. (2025). Meropenem dosing optimization on day 1 and steady state in critically ill patients without significant renal impairment. Scientific Reports, 15 (1) 37781, 1-12. doi: 10.1038/s41598-025-20630-5 |
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2025 Journal Article Continuous or extended vs intermittent infusions of beta-lactam antibiotics in ICU patients with pneumonia: a systematic review and meta-analysis of randomized controlled trialsLi, Yixuan, Roberts, Jason A., Abdul-Aziz, Mohd H. and Sime, Fekade B. (2025). Continuous or extended vs intermittent infusions of beta-lactam antibiotics in ICU patients with pneumonia: a systematic review and meta-analysis of randomized controlled trials. Antimicrobial Agents and Chemotherapy, 69 (10) e0073225, 1-13. doi: 10.1128/aac.00732-25 |
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2025 Journal Article Pharmacological research agenda on adult extracorporeal membrane oxygenation using the Delphi method: a position article of the extracorporeal membrane oxygenation pharmacology networkMorales Castro, Diana, Al-Fares, Abdulrahman Abdullah, Paternoster, Gianluca, Lyster, Haifa, Hohlfelder, Benjamin, Arias Ortiz, Julian, Abdul-Aziz, Mohd Hafiz, Herr, Daniel, Alraish, Rawan, Ferre Contreras, Andrés, Palavecino, Marcela, Milella, Luigi, Watt, Kevin, Alkazemi, Afrah, Carini, Federico Carlos, Roberts, Jason A., Riera Del Brio, Jordi, Parra, Alba Pau, Kakar, Vivek, Dureau, Pauline, Duceppe, Marc-Alexandre, Alm, Mark, Cha, Stephanie, Shekar, Kiran, Dzierba, Amy L. and Extracorporeal Membrane Oxygenation Pharmacology Network (ECMOPharm Net) (2025). Pharmacological research agenda on adult extracorporeal membrane oxygenation using the Delphi method: a position article of the extracorporeal membrane oxygenation pharmacology network. Critical Care Medicine, 53 (11), e2246-e2260. doi: 10.1097/CCM.0000000000006806 |
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2025 Journal Article Optimizing antibiotic dosing: a prospective observational study of piperacillin/tazobactam plasma levels in critically ill patients with augmented renal clearanceNegin, Fahima, Abdul Rahim, Shahir Asraf, Mat Nor, Mohd Basri, Mohamad, Fatimah, Nordin, Nur Sazwi and Abdul-Aziz, Mohd Hafiz (2025). Optimizing antibiotic dosing: a prospective observational study of piperacillin/tazobactam plasma levels in critically ill patients with augmented renal clearance. IIUM Medical Journal Malaysia, 24 (3), 48-53. doi: 10.31436/imjm.v24i03.2607 |
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2025 Journal Article Current practices in outpatient parenteral antimicrobial therapy programmes: an international multi-centre surveyWolie, Zenaw T., Roberts, Jason A., López-Cortés, Luis Eduardo, Mirón-Rubio, Manuel, Pollard, James, Marizan Nor, Afra Nahdia, Abdul-Aziz, Mohd H., Jamieson, Conor, Seaton, R Andrew, Gilchrist, Mark and Sime, Fekade B. (2025). Current practices in outpatient parenteral antimicrobial therapy programmes: an international multi-centre survey. JAC - Antimicrobial Resistance, 7 (3) dlaf075, 1-11. doi: 10.1093/jacamr/dlaf075 |
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2025 Journal Article A Systematic Review of Pharmacokinetic Studies of Colistin and Polymyxin B in Adult PopulationsZamri, Puteri Juanita, Lim, Sazlyna Mohd Sazlly, Sime, Fekade Bruck, Roberts, Jason A. and Abdul-Aziz, Mohd Hafiz (2025). A Systematic Review of Pharmacokinetic Studies of Colistin and Polymyxin B in Adult Populations. Clinical Pharmacokinetics, 64 (5) n71, 1-35. doi: 10.1007/s40262-025-01488-2 |
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2025 Journal Article Continuous versus intermittent bolus dosing of beta-lactam antibiotics in a South African multi-disciplinary intensive care unit: a randomized controlled trialKhan, Ayesha Bibi, Abdul-Aziz, Mohd Hafiz, Hindle, Lucy, Lipman, Jeffrey, Simelela, Fetolang and Omar, Shahed (2025). Continuous versus intermittent bolus dosing of beta-lactam antibiotics in a South African multi-disciplinary intensive care unit: a randomized controlled trial. Journal of Infection, 90 (5) 106487, 1-6. doi: 10.1016/j.jinf.2025.106487 |
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2025 Journal Article Resistance Optimised Antibiotic Dosing (The ROAD Study): Is dosing of meropenem and piperacillin-tazobactam optimised to prevent the emergence of antibiotic resistance safe and feasible in the ICU? A pilot studyRoberts, J. A., Heffernan, A. J., Chai, M. G., Harris, P. N. A., Legg, A., Farkas, A., Laupland, K., Dhanani, J., Fourie, C., Murray, L., Abdul-Aziz, H., Ungerer, J., McWhinney, B., Lipman, J. and Cotta, M. O. (2025). Resistance Optimised Antibiotic Dosing (The ROAD Study): Is dosing of meropenem and piperacillin-tazobactam optimised to prevent the emergence of antibiotic resistance safe and feasible in the ICU? A pilot study. CMI Communications, 2 (1) 105051, 1-7. doi: 10.1016/j.cmicom.2024.105051 |
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2025 Journal Article Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO studyAbdul-Aziz, Mohd H., Diehl, Arne, Liu, Xin, Cheng, Vesa, Corley, Amanda, Gilder, Eileen, Levkovich, Bianca, McGuinness, Shay, Ordonez, Jenny, Parke, Rachael, Pellegrino, Vincent, Wallis, Steven C., Fraser, John F., Shekar, Kiran and Roberts, Jason A. (2025). Population pharmacokinetics of caspofungin in critically ill patients receiving extracorporeal membrane oxygenation—an ASAP ECMO study. Antimicrobial Agents and Chemotherapy, 69 (2) e0143524, 1-15. doi: 10.1128/aac.01435-24 |
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2025 Journal Article Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infectionGiuliano, Simone, Angelini, Jacopo, Campanile, Floriana, Conti, Paola, Flammini, Sarah, Pagotto, Alberto, Sbrana, Francesco, Martini, Luca, D'Elia, Denise, Abdul-Aziz, Mohd H., Cotta, Menino O., Roberts, Jason A., Bonomo, Robert A. and Tascini, Carlo (2025). Evaluation of ampicillin plus ceftobiprole combination therapy in treating Enterococcus faecalis infective endocarditis and bloodstream infection. Scientific Reports, 15 (1) 3519, 1-16. doi: 10.1038/s41598-025-87512-8 |
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2025 Journal Article Propofol and fentanyl pharmacokinetics and pharmacodynamics in extracorporeal membrane oxygenationMorales Castro, Diana, Balzani, Eleonora, Abdul-Aziz, M. Hafiz, Hernandez-Mitre, Maria Patricia, Wong, Irene, Turgeon, Julien, Tisminetzky, Manuel, Jurado-Camacho, Felipe, Morris, Idunn, Dresser, Linda, Granton, John, Uetrecht, Jack, Pang, K. Sandy, Chen, Eric, Shekar, Kiran and Fan, Eddy (2025). Propofol and fentanyl pharmacokinetics and pharmacodynamics in extracorporeal membrane oxygenation. Annals of the American Thoracic Society, 22 (1), 121-129. doi: 10.1513/annalsats.202407-795oc |
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2024 Journal Article Prolonged vs intermittent infusions of β-lactam antibiotics-replyRoberts, Jason A., Devaux, Anthony and Abdul-Aziz, Mohd H. (2024). Prolonged vs intermittent infusions of β-lactam antibiotics-reply. JAMA-Journal of the American Medical Association, 333 (3), 259. doi: 10.1001/jama.2024.23728 |
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2024 Journal Article Is it time to implement prolonged infusions of beta-lactam antibiotics in and beyond critical care settings?Abdul-Aziz, Mohd H., Dulhunty, Joel M., Rajbhandari, Dorrilyn, Roberts, Jason A. and Lipman, Jeffrey (2024). Is it time to implement prolonged infusions of beta-lactam antibiotics in and beyond critical care settings?. Internal Medicine Journal, 54 (12), 1931-1934. doi: 10.1111/imj.16584 |
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2024 Journal Article The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic reviewCree, Michele L., Abdul-Aziz, Mohd Hafiz, Schlapbach, Luregn J., Roberts, Jason A. and Parker, Suzanne (2024). The impact of extracorporeal support on antimicrobial pharmacokinetics in critically ill neonatal and paediatric patients: a systematic review. International Journal of Antimicrobial Agents, 64 (4) 107311, 1-16. doi: 10.1016/j.ijantimicag.2024.107311 |
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2024 Journal Article COVID-19 drug treatments are prone to sequestration in extracorporeal membrane oxygenation circuits: an ex vivo extracorporeal membrane oxygenation studyDhanani, Jayesh A., Shekar, Kiran, Parmar, Dinesh, Lipman, Jeffrey, Bristow, Debra, Wallis, Steven C., Won, Hayoung, Sumi, Chandra D., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2024). COVID-19 drug treatments are prone to sequestration in extracorporeal membrane oxygenation circuits: an ex vivo extracorporeal membrane oxygenation study. ASAIO Journal, 70 (6), 546-552. doi: 10.1097/MAT.0000000000002120 |
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2023 Journal Article Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO studyNovy, Emmanuel, Abdul-Aziz, Mohd H., Cheng, Vesa, Burrows, Fay, Buscher, Hergen, Corley, Amanda, Diehl, Arne, Gilder, Eileen, Levkovich, Bianca J., McGuinness, Shay, Ordonez, Jenny, Parke, Rachael, Parker, Suzanne, Pellegrino, Vincent, Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan A., Fraser, John F., Shekar, Kiran and Roberts, Jason A. (2023). Population pharmacokinetics of fluconazole in critically ill patients receiving extracorporeal membrane oxygenation and continuous renal replacement therapy: an ASAP ECMO study. Antimicrobial Agents and Chemotherapy, 68 (1) e0120123, e0120123. doi: 10.1128/aac.01201-23 |
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2023 Journal Article In silico evaluation of a beta‐lactam dosing guideline among adults with serious infectionsWilliams, Paul, Cotta, Menino Osbert, Abdul‐Aziz, Mohd H., Wilks, Kathryn, Farkas, Andras and Roberts, Jason A. (2023). In silico evaluation of a beta‐lactam dosing guideline among adults with serious infections. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 43 (11), 1121-1130. doi: 10.1002/phar.2753 |
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2023 Journal Article In silico evaluation of a vancomycin dosing guideline among adults with serious infectionsWilliams, Paul, Cotta, Menino Osbert, Abdul-Aziz, Mohd H., Wilks, Kathryn, Farkas, Andras and Roberts, Jason A (2023). In silico evaluation of a vancomycin dosing guideline among adults with serious infections. Therapeutic Drug Monitoring, 45 (5), 631-636. doi: 10.1097/FTD.0000000000001102 |
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2023 Journal Article Why is the implementation of beta-lactam therapeutic drug monitoring for the critically ill falling short? A multicenter mixed-methods studyBarreto, Erin F., Chitre, Pooja N., Pine, Kathleen H., Shepel, Kathryn K., Rule, Andrew D., Alshaer, Mohammad H., Abdul Aziz, Mohd Hafiz, Roberts, Jason A., Scheetz, Marc H., Ausman, Sara E., Moreland-Head, Lindsay N., Rivera, Christina G., Jannetto, Paul J., Mara, Kristin C. and Boehmer, Kasey R. (2023). Why is the implementation of beta-lactam therapeutic drug monitoring for the critically ill falling short? A multicenter mixed-methods study. Therapeutic Drug Monitoring, 45 (4), 508-518. doi: 10.1097/FTD.0000000000001059 |
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2023 Journal Article Dalbavancin as suppressive antibiotic therapy in patients with prosthetic infections: efficacy and safetyRuiz-Sancho, Andrés, Núñez-Núñez, María, Castelo-Corral, Laura, Martínez-Marcos, Francisco Javier, Lois-Martínez, Nagore, Abdul-Aziz, Mohd Hafiz and Vinuesa-García, David (2023). Dalbavancin as suppressive antibiotic therapy in patients with prosthetic infections: efficacy and safety. Frontiers in Pharmacology, 14 1185602, 1185602. doi: 10.3389/fphar.2023.1185602 |