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2017

Journal Article

Overexpression of the regulatory subunit of glutamate-cysteine ligase enhances monoclonal antibody production in CHO cells

Orellana, Camila A., Marcellin, Esteban, Gray, Peter P. and Nielsen, Lars K. (2017). Overexpression of the regulatory subunit of glutamate-cysteine ligase enhances monoclonal antibody production in CHO cells. Biotechnology and Bioengineering, 114 (8), 1825-1836. doi: 10.1002/bit.26316

Overexpression of the regulatory subunit of glutamate-cysteine ligase enhances monoclonal antibody production in CHO cells

2017

Journal Article

Awakening sleeping beauty: production of propionic acid in Escherichia coli through the sbm operon requires the activity of a methylmalonyl-CoA epimerase

Gonzalez-Garcia, Ricardo Axayacatl, McCubbin, Tim, Wille, Annalena, Plan, Manuel, Nielsen, Lars Keld and Marcellin, Esteban (2017). Awakening sleeping beauty: production of propionic acid in Escherichia coli through the sbm operon requires the activity of a methylmalonyl-CoA epimerase. Microbial Cell Factories, 16 (1) 121, 121. doi: 10.1186/s12934-017-0735-4

Awakening sleeping beauty: production of propionic acid in Escherichia coli through the sbm operon requires the activity of a methylmalonyl-CoA epimerase

2017

Journal Article

Maintenance of ATP homeostasis triggers metabolic shifts in gas-fermenting acetogens

Valgepea, Kaspar, Lemgruber, Renato de Souza Pinto, Meaghan, Kieran, Palfreyman, Robin William, Abdalla, Tanus, Heijstra, Bjom Daniel, Behrendorff, James Bruce, Tappel, Ryan, Kopke, Michael, Simpson, Sean Dennis, Nielsen, Lars Keld and Marcellin, Esteban (2017). Maintenance of ATP homeostasis triggers metabolic shifts in gas-fermenting acetogens. Cell Systems, 4 (5), 505-515.e5. doi: 10.1016/j.cels.2017.04.008

Maintenance of ATP homeostasis triggers metabolic shifts in gas-fermenting acetogens

2017

Journal Article

Microbial Propionic Acid Production

Gonzalez Garcia, Ricardo Axayacatl, McCubbin, Timothy, Navone, Laura, Stowers, Chris, Nielsen, Lars K. and Marcellin Saldana, Esteban Stefane (2017). Microbial Propionic Acid Production. Fermentation, 3 (2) 3020021, 1-20. doi: 10.3390/fermentation3020021

Microbial Propionic Acid Production

2017

Journal Article

Arginine deiminase pathway provides ATP and boosts growth of the gas-fermenting acetogen Clostridium autoethanogenum

Valgepea, Kaspar, Loi, Kim Q., Behrendorff, James B., Lemgruber, Renato de S. P., Plan, Manuel, Hodson, Mark P., Koepke, Michael, Nielsen, Lars K. and Marcellin, Esteban (2017). Arginine deiminase pathway provides ATP and boosts growth of the gas-fermenting acetogen Clostridium autoethanogenum. Metabolic Engineering, 41, 202-211. doi: 10.1016/j.ymben.2017.04.007

Arginine deiminase pathway provides ATP and boosts growth of the gas-fermenting acetogen Clostridium autoethanogenum

2017

Journal Article

Genome sequence of Propionibacterium acidipropionici ATCC 55737

Luna-Flores, Carlos H., Nielsen, Lars K. and Marcellin, Estaban (2017). Genome sequence of Propionibacterium acidipropionici ATCC 55737. Genome Announcements, 4 (3) e00248-16. doi: 10.1128/genomeA.00248-16

Genome sequence of Propionibacterium acidipropionici ATCC 55737

2017

Journal Article

Improved production of propionic acid using genome shuffling

Luna-Flores, Carlos H., Palfreyman, Robin W., Kromer, Jens O., Nielsen, Lars K. and Marcellin, Esteban (2017). Improved production of propionic acid using genome shuffling. Biotechnology Journal, 12 (2) 1600120, 1600120. doi: 10.1002/biot.201600120

Improved production of propionic acid using genome shuffling

2016

Journal Article

Deletion of the hypothetical protein SCO2127 of Streptomyces coelicolor allowed identification of a new regulator of actinorhodin production

Tierrafría, Víctor H. , Licona-Cassani, Cuauhtemoc, Maldonado-Carmona, Nidia, Romero-Rodríguez, Alba, Centeno-Leija, Sara, Marcellin, Esteban, Rodríguez-Sanoja, Romina, Ruiz-Villafan, Beatriz, Nielsen, Lars K. and Sánchez, Sergio (2016). Deletion of the hypothetical protein SCO2127 of Streptomyces coelicolor allowed identification of a new regulator of actinorhodin production. Applied Microbiology and Biotechnology, 100 (21), 9229-9237. doi: 10.1007/s00253-016-7811-2

Deletion of the hypothetical protein SCO2127 of Streptomyces coelicolor allowed identification of a new regulator of actinorhodin production

2016

Journal Article

High performance targeted mass spectrometry with precision data independent acquisition reveals site-specific glycosylation macroheterogeneity

Yeo, K. Y. Benjamin, Chrysanthopoulos, Panangiotis K., Nouwens, Amanda S., Marcellin, Esteban and Schulz, Benjamin L. (2016). High performance targeted mass spectrometry with precision data independent acquisition reveals site-specific glycosylation macroheterogeneity. Analytical Biochemistry, 510, 106-113. doi: 10.1016/j.ab.2016.06.009

High performance targeted mass spectrometry with precision data independent acquisition reveals site-specific glycosylation macroheterogeneity

2016

Journal Article

Tetanus toxin production is triggered by the transition from amino acid consumption to peptides

Licona-Cassani, Cuauhtemoc, Steen, Jennifer A., Zaragoza, Nicolas E., Moonen, Glenn, Moutafis, George, Hodson, Mark P., Power, John, Nielsen, Lars K. and Marcellin, Esteban (2016). Tetanus toxin production is triggered by the transition from amino acid consumption to peptides. Anaerobe, 41, 113-124. doi: 10.1016/j.anaerobe.2016.07.006

Tetanus toxin production is triggered by the transition from amino acid consumption to peptides

2016

Journal Article

Low carbon fuels and commodity chemicals from waste gases-systematic approach to understand energy metabolism in a model acetogen

Marcellin, Esteban, Behrendorff, James B., Nagaraju, Shilpa, DeTissera, Sashini, Segovia, Simon, Palfreyman, Robin W., Daniell, James, Licona-Cassani, Cuauhtemoc, Quek, Lake-ee, Speight, Robert, Hodson, Mark P., Simpson, Sean D., Mitchell, Wayne P., Kopke, Michael and Nielsen, Lars K. (2016). Low carbon fuels and commodity chemicals from waste gases-systematic approach to understand energy metabolism in a model acetogen. Green Chemistry, 18 (10), 3020-3028. doi: 10.1039/c5gc02708j

Low carbon fuels and commodity chemicals from waste gases-systematic approach to understand energy metabolism in a model acetogen

2016

Journal Article

Cyclic-di-AMP synthesis by the diadenylate cyclase CdaA is modulated by the peptidoglycan biosynthesis enzyme GlmM in Lactococcus lactis

Zhu, Yan, Pham, Thi Huong, Nhiep, Thi Hanh Nguyen, Vu, Ngoc Minh Thu, Marcellin, Esteban, Chakrabortti, Alolika, Wang, Yuanliang, Waanders, Jennifer, Lo, Raquel, Huston, Wilhelmina M., Bansal, Nidhi, Nielsen, Lars K., Liang, Zhao-Xun and Turner, Mark S. (2016). Cyclic-di-AMP synthesis by the diadenylate cyclase CdaA is modulated by the peptidoglycan biosynthesis enzyme GlmM in Lactococcus lactis. Molecular Microbiology, 99 (6), 1015-1027. doi: 10.1111/mmi.13281

Cyclic-di-AMP synthesis by the diadenylate cyclase CdaA is modulated by the peptidoglycan biosynthesis enzyme GlmM in Lactococcus lactis

2016

Journal Article

Replenishing the cyclic-di-AMP pool: regulation of diadenylate cyclase activity in bacteria

Pham, Thi Huong, Liang, Zhao-Xun, Marcellin, Esteban and Turner, Mark S. (2016). Replenishing the cyclic-di-AMP pool: regulation of diadenylate cyclase activity in bacteria. Current Genetics, 62 (4), 1-8. doi: 10.1007/s00294-016-0600-8

Replenishing the cyclic-di-AMP pool: regulation of diadenylate cyclase activity in bacteria

2016

Book Chapter

Metabolic pathway engineering for hyaluronic acid production

Marcellin, Esteban, Chen, Wendy Y. and Nielsen, Lars K. (2016). Metabolic pathway engineering for hyaluronic acid production. Handbook of carbohydrate-modifying biocatalysts. (pp. 683-696) edited by Peter Grunwald. Singapore: Pan Stanford Publishing. doi: 10.1201/9781315185392-21

Metabolic pathway engineering for hyaluronic acid production

2015

Journal Article

Systems biology approaches to understand natural products biosynthesis

Licona-Cassani, Cuauhtemoc, Cruz-Morales, Pablo, Manteca, Angel, Barona-Gomez, Francisco, Nielsen, Lars K. and Marcellin, Esteban (2015). Systems biology approaches to understand natural products biosynthesis. Frontiers in Bioengineering and Biotechnology, 3 199, 199.1-199.8. doi: 10.3389/fbioe.2015.00199

Systems biology approaches to understand natural products biosynthesis

2015

Journal Article

Global dynamics of Escherichia coli phosphoproteome in central carbon metabolism under changing culture conditions

Lim, SooA, Marcellin, Esteban, Jacob, Shana and Nielsen, Lars K. (2015). Global dynamics of Escherichia coli phosphoproteome in central carbon metabolism under changing culture conditions. Journal of Proteomics, 126, 24-33. doi: 10.1016/j.jprot.2015.05.021

Global dynamics of Escherichia coli phosphoproteome in central carbon metabolism under changing culture conditions

2015

Journal Article

High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis

Orellana, Camila A., Marcellin, Esteban, Schulz, Benjamin L., Nouwens, Amanda S., Gray, Peter P. and Nielsen, Lars K. (2015). High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis. Journal of Proteome Research, 14 (2), 609-618. doi: 10.1021/pr501027c

High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis

2015

Conference Publication

A pan-genomic guided metabolic reconstruction and omics integration to understand Propionibacterium metabolism

McCubbins, Tim, Nielsen, Lars. K. and Marcellin, Esteban (2015). A pan-genomic guided metabolic reconstruction and omics integration to understand Propionibacterium metabolism. 4th Conference on Constraint-Based Reconstruction and Analysis (COBRA 2015), Heidelberg, Germany, 16 - 18 September 2015.

A pan-genomic guided metabolic reconstruction and omics integration to understand Propionibacterium metabolism

2015

Journal Article

AllR controls the expression of Streptomyces coelicolor allantoin pathway genes

Navone, Laura, Pablo Macagno, Juan, Licona-Cassani, Cuauhtemoc, Marcellin, Esteban, Nielsen, Lars K., Gramajo, Hugo and Rodriguez, Eduardo (2015). AllR controls the expression of Streptomyces coelicolor allantoin pathway genes. Applied and Environmental Microbiology, 81 (19), 6649-6659. doi: 10.1128/AEM.02098-15

AllR controls the expression of Streptomyces coelicolor allantoin pathway genes

2015

Conference Publication

Opening pandora’s box

Marcellin, Esteban and Nielsen, Lars Keld (2015). Opening pandora’s box. Biochemical and Molecular Engineering XIX, Puerto Vallarta, Mexico, 12-16 July 2015.

Opening pandora’s box