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2010 Journal Article Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in miceHarrison, Rosemary S., Ruiz-Gomez, Gloria, Hill, Timothy A., Chow, Shiao Y., Shepherd, Nicholas E., Lohman, Rink-Jan, Abbenante, Giovanni, Hoang, Huy N. and Fairlie, David P. (2010). Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice. Journal of Medicinal Chemistry, 53 (23), 8400-8408. doi: 10.1021/jm101139f |
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2010 Journal Article The antiplasmodial activity of norcantharidin analogsBajsa, Joanna, McCluskey, Adam, Gordon, Christopher P., Stewart, Scott G., Hill, Timothy A., Sahu, Rajnish, Duke, Stephen O. and Tekwani, Babu L. (2010). The antiplasmodial activity of norcantharidin analogs. Bioorganic and Medicinal Chemistry Letters, 20 (22), 6688-6695. doi: 10.1016/j.bmcl.2010.09.004 |
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2010 Journal Article Update 1 of: Beta-strand mimeticsLoughlin, Wendy A., Tyndall, Joel D. A., Glenn, Matthew P., Hill, Timothy A. and Fairlie, David P. (2010). Update 1 of: Beta-strand mimetics. Chemical Reviews, 110 (6), 1-38. doi: 10.1021/cr900395y |
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2010 Journal Article Update 1 of: beta-strand mimeticsLoughlin, Wendy A., Tyndall, Joel D. A., Glenn, Matthew P., Hill, Timothy A. and Fairlie, David P. (2010). Update 1 of: beta-strand mimetics. Chemical Reviews, 110 (6), PR32-PR69. doi: 10.1021/cr040648k |
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2010 Journal Article Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potencyHarrison, Rosemary S., Shepherd, Nicholas E., Hoang, Huy N., Ruiz-Goméz, Gloria, Hill, Timothy A., Driver, Russell W., Desai, Vishal S., Young, Paul R., Abbenante, Giovanni and Fairlie, David P. (2010). Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency. Proceedings of the National Academy of Sciences of the United States of America, 107 (26), 11686-11691. doi: 10.1073/pnas.1002498107 |
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2010 Journal Article Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosisHill, Timothy A., Mariana, Anna, Gordon, Christopher P., Odell, Luke R., Robertson, Mark J., McGeachie, Andrew B., Chau, Ngoc, Daniel, James A., Gorgani, Nick N., Robinson, Phillip J. and McCluskey, Adam (2010). Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis. Journal of Medicinal Chemistry, 53 (10), 4094-4102. doi: 10.1021/jm100119c |
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2009 Journal Article Inhibition of dynamin mediated endocytosis by the Dynoles - synthesis and functional activity of a family of indolesHill, Timothy A., Gordon, Christopher P., McGeachie, Andrew B., Venn-Brown, Barbara, Odell, Luke R., Chau, Ngoc, Quan, Annie, Mariana, Anna, Sakoff, Jennette A., Chircop (nee Fabbro), Megan, Robinson, Phillip J. and McCluskey, Adam (2009). Inhibition of dynamin mediated endocytosis by the Dynoles - synthesis and functional activity of a family of indoles. Journal of Medicinal Chemistry, 52 (12), 3762-3773. doi: 10.1021/jm900036m |
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2008 Journal Article Norcantharidin analogues: Synthesis, anticancer activity and protein phosphatase 1 and 2A inhibitionHill, Timothy A., Stewart, Scott G., Gordon, Christopher P., Ackland, Stephen P., Gilbert, Jayne, Sauer, Benjamin, Sakoff, Jennette A. and McCluskey, Adam (2008). Norcantharidin analogues: Synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition. ChemMedChem, 3 (12), 1878-1892. doi: 10.1002/cmdc.200800192 |
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2007 Journal Article Synthesis and biological evaluation of norcantharidin analogues: Towards PP1 selectivityStewart, Scott G., Hill, Timothy A., Gilbert, Jayne, Ackland, Stephen P., Sakoff, Jennette A. and McCluskey, Adam (2007). Synthesis and biological evaluation of norcantharidin analogues: Towards PP1 selectivity. Bioorganic & Medicinal Chemistry, 15 (23), 7301-7310. doi: 10.1016/j.bmc.2007.08.028 |
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2007 Journal Article Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluationHill, Timothy A., Stewart, Scott G., Ackland, Stephen P., Gilbert, Jayne, Sauer, Benjamin, Sakoff, Jennette and McCluskey, Adam (2007). Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation. Bioorganic & Medicinal Chemistry, 15 (18), 6126-6134. doi: 10.1016/j.bmc.2007.06.034 |
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2007 Journal Article Heterocyclic substituted cantharidin and norcantharidin analogues—synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activityHill, Timothy A., Stewart, Scott G., Sauer, Benjamin, Gilbert, Jayne, Ackland, Stephen P., Sakoff, Jennette A. and McCluskey, Adam (2007). Heterocyclic substituted cantharidin and norcantharidin analogues—synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity. Bioorganic & Medicinal Chemistry Letters, 17 (12), 3392-3397. doi: 10.1016/j.bmcl.2007.03.093 |
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2005 Journal Article Small molecule inhibitors of dynamin I GTPase activity: Development of dimeric tyrphostinsHill, Timothy, Odell, Luke R., Edwards, Jennifer K., Graham, Mark E., McGeachie, Andrew B., Rusak, Jenny, Quan, Annie, Abagyan, Ruben, Scott, Janet L., Robinson, Phillip J. and McCluskey, Adam (2005). Small molecule inhibitors of dynamin I GTPase activity: Development of dimeric tyrphostins. Journal of Medicinal Chemistry, 48 (24), 7781-7788. doi: 10.1021/jm040208l |
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2005 Journal Article BiCl3-mediated opening of epoxides, a facile route to chlorohydrins or amino alcohols: One reagent, two pathsMcCluskey, Adam, Leitch, Sarah K., Garner, James, Caden, Christine E., Hill, Timothy A., Odell, Luke R. and Stewart, Scott G. (2005). BiCl3-mediated opening of epoxides, a facile route to chlorohydrins or amino alcohols: One reagent, two paths. Tetrahedron Letters, 46 (47), 8229-8232. doi: 10.1016/j.tetlet.2005.09.088 |
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2005 Journal Article Parallel solution-phase synthesis of targeted tyrphostin libraries with anticancer activityHill, Timothy A., Sakoff, Jennette A., Robinson, Phillip J. and McCluskey, Adam (2005). Parallel solution-phase synthesis of targeted tyrphostin libraries with anticancer activity. Australian Journal of Chemistry, 58 (2), 94-103. doi: 10.1071/CH04143 |
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2004 Journal Article Identification of aminopyrimidine regioisomers via line broadening effects in 1H and 13C NMR spectroscopyGarner, James, Hill, Tim, Odell, Luke, Keller, Paul, Morgan, Jody and McCluskey, Adam (2004). Identification of aminopyrimidine regioisomers via line broadening effects in 1H and 13C NMR spectroscopy. Australian Journal of Chemistry, 57 (11), 1079-1083. doi: 10.1071/CH03316 |
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2004 Journal Article Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activityHill, Timothy A., Odell, Luke R., Quan, Annie, Abagyan, Ruben, Ferguson, Gemma, Robinson, Phillip J. and McCluskey, Adam (2004). Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity. Bioorganic & Medicinal Chemistry Letters, 14 (12), 3275-3278. doi: 10.1016/j.bmcl.2004.03.096 |
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2002 Journal Article Green chemistry approaches to the Knoevenagel condensation: Comparison of ethanol, water and solvent free (dry grind) approachesMcCluskey, A, Robinson, PJ, Hill, T, Scott, JL and Edwards, JK (2002). Green chemistry approaches to the Knoevenagel condensation: Comparison of ethanol, water and solvent free (dry grind) approaches. Tetrahedron Letters, 43 (17), 3117-3120. doi: 10.1016/S0040-4039(02)00480-X |
