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2020 Conference Publication Total Calcium Content of Sarcoplasmic Reticulum and Mitochondria in Ryanodine Receptor Variant MuscleLamboley, Cedric R., Pearce, Luke and Launikonis, Bradley S. (2020). Total Calcium Content of Sarcoplasmic Reticulum and Mitochondria in Ryanodine Receptor Variant Muscle. In: 64th Annual Meeting of the Biophysical Society, San Diego, CA United States, (98A-99A). 15-19 February 2020. |
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2019 Journal Article Components of activation heat in skeletal muscleBarclay, C. J. and Launikonis, B. S. (2019). Components of activation heat in skeletal muscle. Journal of Muscle Research and Cell Motility, 42 (1), 1-16. doi: 10.1007/s10974-019-09547-5 |
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2019 Journal Article Mechanistic insights into store-operated Ca 2+ entry during excitation-contraction coupling in skeletal muscleKoenig, Xaver, Choi, Rocky H., Schicker, Klaus, Singh, Daniel P., Hilber, Karlheinz and Launikonis, Bradley S. (2019). Mechanistic insights into store-operated Ca 2+ entry during excitation-contraction coupling in skeletal muscle. Biochimica et Biophysica Acta, 1866 (7), 1239-1248. doi: 10.1016/j.bbamcr.2019.02.014 |
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2019 Conference Publication High-throughput screening yields allosteric inhibitors of leaky RyRs for therapeutic developmentRebbeck, Robyn T., Singh, Daniel P., Ginsburg, Kenneth S., Dong, Xiaoqiong, Thomas, David D., Bers, Donald M., Launikonis, Bradley S. and Cornea, Razvan L. (2019). High-throughput screening yields allosteric inhibitors of leaky RyRs for therapeutic development. 63rd Annual Meeting of the Biophysical Society, Baltimore, MD, United States, 2-6 March, 2019. St. Louis, MO, United States: Cell Press. doi: 10.1016/j.bpj.2018.11.2062 |
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2019 Conference Publication Determination of heat production in human skeletal muscle from measurements of basal Ca2+ movementsBarclay, Christopher J. and Launikonis, Bradley S. (2019). Determination of heat production in human skeletal muscle from measurements of basal Ca2+ movements. 63rd Annual Meeting of the Biophysical Society, Baltimore, MD, United States, 2-6 March 2019. St. Louis, MO, United States: Cell Press. doi: 10.1016/j.bpj.2018.11.2805 |
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2018 Journal Article Junctional membrane Ca dynamics in human muscle fibers are altered by malignant hyperthermia causative RyR mutationCully, Tanya R., Choi, Rocky H., Bjorksten, Andrew R., Stephenson, D. George, Murphy, Robyn M. and Launikonis, Bradley S. (2018). Junctional membrane Ca dynamics in human muscle fibers are altered by malignant hyperthermia causative RyR mutation. Proceedings of the National Academy of Sciences of the United States of America, 115 (32), 201800490-8220. doi: 10.1073/pnas.1800490115 |
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2018 Journal Article Store-operated Ca2+ entry is activated by every action potential in skeletal muscleKoenig, Xaver, Choi, Rocky H. and Launikonis, Bradley S. (2018). Store-operated Ca2+ entry is activated by every action potential in skeletal muscle. Communications Biology, 1 (1) 31, 31. doi: 10.1038/s42003-018-0033-7 |
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2018 Journal Article NHE- and diffusion-dependent proton fluxes across the tubular system membranes of fast-twitch muscle fibers of the ratLaunikonis, Bradley S., Cully, Tanya R., Csernoch, Laszlo and Stephenson, D. George (2018). NHE- and diffusion-dependent proton fluxes across the tubular system membranes of fast-twitch muscle fibers of the rat. The Journal of General Physiology, 150 (1), 95-110. doi: 10.1085/jgp.201711891 |
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2018 Conference Publication Every Action Potential Activates Store-Operated Ca2+ Entry in Skeletal MuscleKoenig, Xaver and Launikonis, Bradley S. (2018). Every Action Potential Activates Store-Operated Ca2+ Entry in Skeletal Muscle. 62nd Annual Meeting of the Biophysical-Society, San Francisco, CA, United States, Feb 17-21, 2018. Cambridge, MA United States: Cell Press. |
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2018 Conference Publication High-throughput screening yields allosteric inhibitors of leaky RyRS for therapeutic applicationsRebbeck, Robyn T., Dong, Xiaoqiong, Ginsburg, Kenneth S., Singh, Daniel P., Gillispie, Gregory D., Thomas, David D., Launikonis, Bradley S., Bers, Donald M. and Cornea, Razvan L. (2018). High-throughput screening yields allosteric inhibitors of leaky RyRS for therapeutic applications. 62nd Annual Meeting of the Biophysical Society, San Francisco, California, 17-21 February 2018. St. Louis, MO, United States: Cell Press. |
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2017 Journal Article Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrestMills, Richard J., Titmarsh, Drew M., Koenig, Xaver, Parker, Benjamin L., Ryall, James G., Quaife-Ryan, Gregory A., Voges, Holly K., Hodson, Mark P., Ferguson, Charles, Drowley, Lauren, Plowright, Alleyn T., Needham, Elise J., Wang, Qing-Dong, Gregorevic, Paul, Xin, Mei, Thomas, Walter G., Parton, Robert G., Nielsen, Lars K., Launikonis, Bradley S., James, David E., Elliott, David A., Porrello, Enzo R. and Hudson, James E. (2017). Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Proceedings of the National Academy of Sciences of the United States of America, 114 (40), E8372-E8381. doi: 10.1073/pnas.1707316114 |
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2017 Journal Article Dantrolene requires Mg2+ to arrest malignant hyperthermiaChoi, Rocky H., Koenig, Xaver and Launikonis, Bradley S. (2017). Dantrolene requires Mg2+ to arrest malignant hyperthermia. Proceedings of the National Academy of Sciences of the United States of America, 114 (18), 4811-4815. doi: 10.1073/pnas.1619835114 |
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2017 Journal Article Doublet stimulation increases Ca2+ binding to troponin C to ensure rapid force development in skeletal muscleBakker, Anthony J., Cully, Tanya R., Wingate, Catherine D., Barclay, Christopher J. and Launikonis, Bradley S. (2017). Doublet stimulation increases Ca2+ binding to troponin C to ensure rapid force development in skeletal muscle. Journal of General Physiology, 149 (3), 323-334. doi: 10.1085/jgp.201611727 |
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2017 Journal Article Human skeletal muscle plasmalemma alters its structure to change its Ca2+-handling following heavy-load resistance exerciseCully, Tanya R., Murphy, Robyn M., Roberts, Llion, Raastad, Truls, Fassett, Robert G., Coombes, Jeff S., Jayasinghe, Isuru D. and Launikonis, Bradley S. (2017). Human skeletal muscle plasmalemma alters its structure to change its Ca2+-handling following heavy-load resistance exercise. Nature Communications, 8 (1) 14266, 14266.1-14266.10. doi: 10.1038/ncomms14266 |
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2017 Conference Publication Towards the role of store-operated Ca2+ entry in skeletal muscle physiologyKoenig, X. and Launikonis, B. S. (2017). Towards the role of store-operated Ca2+ entry in skeletal muscle physiology. Joint Meeting of the Federation of European Physiological Societies and the Austrian Physiological Society with Participation of the Czech, French, Italian, Slovak, Slovenian, Swiss and Turkish Physiological Societies, Vienna, Austria, 13–15 September 2017. Chichester, West Sussex United Kingdom: Wiley. |
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2017 Conference Publication Genetic and histological characterisation of excitation-contraction coupling related structural myopathy cohortBeecroft, S., Choi, R., McLean, C., Olive, M., Ryan, M., Davis, M., Laing, N., Launikonis, B. and Ravenscroft, G. (2017). Genetic and histological characterisation of excitation-contraction coupling related structural myopathy cohort. 22nd International Annual Congress of the World-Muscle-Society (WMS), Saint Malo France, 3-7 October 2017. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.nmd.2017.06.023 |
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2017 Conference Publication Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrestHudson, J., Mills, R., Titmarsh, D., Koenig, X., Parker, B., Ryall, J., Quaife-Ryan, G., Voges, H., Hodson, M., Ferguson, C., Drowley, L., Plowright, A., Wang, Q., Gregorevic, P., Xin, M., Thomas, W., Parton, R., Nielsen, L., Launikonis, B., James, D., Elliott, D. and Porrello, E. (2017). Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Abstracts for the 65th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Perth, Australia, 10 - 13 August 2017. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2017.06.375 |
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2017 Conference Publication Dantrolene Shifts the Affinity of the Ryanodine Receptor for MG(2+)Choi, Rocky H., Konig, F. Xaver, Cully, Tanya R. and Launikonis, Bradley S. (2017). Dantrolene Shifts the Affinity of the Ryanodine Receptor for MG(2+). 61st Annual Meeting of the Biophysical-Society, New Orleans, LA United States, Feb 11-15, 2017. Cambridge, MA United States: Cell Press. doi: 10.1016/j.bpj.2016.11.584 |
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2016 Journal Article A quantitative description of tubular system Ca2+ handling in fast- and slow-twitch muscle fibresCully, Tanya R., Edwards, Joshua N., Murphy, Robyn M. and Launikonis, Bradley S. (2016). A quantitative description of tubular system Ca2+ handling in fast- and slow-twitch muscle fibres. Journal of Physiology, 594 (11), 2795-2810. doi: 10.1113/JP271658 |
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2016 Journal Article Leaky ryanodine receptors delay the activation of store overload-induced Ca2+ release, a mechanism underlying malignant hyperthermia-like events in dystrophic muscleCully, Tanya R. and Launikonis, Bradley S. (2016). Leaky ryanodine receptors delay the activation of store overload-induced Ca2+ release, a mechanism underlying malignant hyperthermia-like events in dystrophic muscle. American Journal of Physiology: Cell Physiology, 310 (8), C673-C680. doi: 10.1152/ajpcell.00366.2015 |
