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2025 Journal Article pH of Microenvironment Directly Modulates the Phenotype and Function of Cancer-Associated FibroblastsLi, Ying, He, Chao, Shen, Ai Ning, Wang, Yu, Xu, Zhi Ping, Zhang, Lingxiao and Wang, Ran (2025). pH of Microenvironment Directly Modulates the Phenotype and Function of Cancer-Associated Fibroblasts. ACS Omega, 10 (4), 3937-3943. doi: 10.1021/acsomega.4c09716 |
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2024 Journal Article Morphology and temporal interactions of silica particles influence the chemotherapeutic cancer cell deathSharma, Astha, Yan, Jiachen, Siwakoti, Prakrit, Saeed, Ayad, Agarwal, Vipul, Xu, Zhi Ping, Wang, Ran and Kumeria, Tushar (2024). Morphology and temporal interactions of silica particles influence the chemotherapeutic cancer cell death. Nano TransMed, 3 100053. doi: 10.1016/j.ntm.2024.100053 |
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2024 Journal Article Next-generation aluminum adjuvants: immunomodulatory layered double hydroxides NanoAlum reengineered from first-line drugsSu, Zhenwei, Boucetta, Hamza, Shao, Jiahui, Huang, Jinling, Wang, Ran, Shen, Aining, He, Wei, Xu, Zhi Ping and Zhang, Lingxiao (2024). Next-generation aluminum adjuvants: immunomodulatory layered double hydroxides NanoAlum reengineered from first-line drugs. Acta Pharmaceutica Sinica B, 14 (11), 4665-4682. doi: 10.1016/j.apsb.2024.09.012 |
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2024 Journal Article Genome-wide assessment of shared genetic landscape of idiopathic pulmonary fibrosis and its comorbiditiesYang, Yuanhao, Sheng, Yong H., Carreira, Patricia, Wang, Tong, Zhao, Huiying and Wang, Ran (2024). Genome-wide assessment of shared genetic landscape of idiopathic pulmonary fibrosis and its comorbidities. Human Genetics, 143 (9-10), 1223-1239. doi: 10.1007/s00439-024-02696-9 |
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2024 Journal Article Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitisSajiir, Haressh, Keshvari, Sahar, Wong, Kuan Yau, Borg, Danielle J., Steyn, Frederik J., Fercher, Christian, Taylor, Karin, Taylor, Breten, Barnard, Ross T., Müller, Alexandra, Moniruzzaman, Md, Miller, Gregory, Wang, Ran, Fotheringham, Amelia, Schreiber, Veronika, Sheng, Yong Hua, Hancock, Janelle Louise, Loo, Dorothy, Burr, Lucy, Huynh, Tony, Lockett, Jack, Ramm, Grant A., Macdonald, Graeme A., Prins, Johannes B., McGuckin, Michael A. and Hasnain, Sumaira Z. (2024). Liver and pancreatic-targeted interleukin-22 as a therapeutic for metabolic dysfunction-associated steatohepatitis. Nature Communications, 15 (1) 4528, 1-13. doi: 10.1038/s41467-024-48317-x |
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2024 Journal Article Mechanistic insight: linking cardiovascular complications of inflammatory bowel diseaseKumarapperuma, Hirushi, Wang, Ran, Little, Peter J and Kamato, Danielle (2024). Mechanistic insight: linking cardiovascular complications of inflammatory bowel disease. Trends in Cardiovascular Medicine, 34 (3), 203-211. doi: 10.1016/j.tcm.2023.01.002 |
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2023 Journal Article Interleukin-22 suppresses major histocompatibility complex II in mucosal epithelial cellsMoniruzzaman, Md, Rahman, M. Arifur, Wang, Ran, Wong, Kuan Yau, Chen, Alice C. -H., Mueller, Alexandra, Taylor, Steven, Harding, Alexa, Illankoon, Thishan, Wiid, Percival, Sajiir, Haressh, Schreiber, Veronika, Burr, Lucy D., McGuckin, Michael A., Phipps, Simon and Hasnain, Sumaira Z. (2023). Interleukin-22 suppresses major histocompatibility complex II in mucosal epithelial cells. The Journal of Experimental Medicine, 220 (11) e20230106. doi: 10.1084/jem.20230106 |
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2023 Journal Article GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infectionFoo, Cheng Xiang, Bartlett, Stacey, Chew, Keng Yih, Ngo, Minh Dao, Bielefeldt-Ohmann, Helle, Jayakody Arachchige, Buddhika, Matthews, Benjamin, Reed, Sarah, Wang, Ran, Smith, Christian, Sweet, Matthew J., Burr, Lucy, Bisht, Kavita, Shatunova, Svetlana, Sinclair, Jane E., Parry, Rhys, Yang, Yuanhao, Lévesque, Jean-Pierre, Khromykh, Alexander, Rosenkilde, Mette Marie, Short, Kirsty R. and Ronacher, Katharina (2023). GPR183 antagonism reduces macrophage infiltration in influenza and SARS-CoV-2 infection. European Respiratory Journal, 61 (3) 2201306, 1-15. doi: 10.1183/13993003.01306-2022 |
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2022 Journal Article IL-20 activates ERK1/2 and suppresses splicing of X-box protein-1 in intestinal epithelial cells but does not improve pathology in acute or chronic models of colitisMoniruzzaman, Md., Wong, Kuan Yau, Wang, Ran, Symon, Hamish, Mueller, Alexandra, Rahman, M. Arifur and Hasnain, Sumaira Z. (2022). IL-20 activates ERK1/2 and suppresses splicing of X-box protein-1 in intestinal epithelial cells but does not improve pathology in acute or chronic models of colitis. International Journal of Molecular Sciences, 24 (1) 174, 174. doi: 10.3390/ijms24010174 |
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2022 Conference Publication A novel role for interleukin-22 signaling in modulating mucosal epithelial cell antigen presentation machinery to control diseaseRahman, M. A., Moniruzzaman, M., Wang, R., Harding, A., Wiid, P., Sajiir, H., Yong, K. Y., Sheng, Y., Mueller, A., Symon, H., Varelias, A., McGuckin, M., Phipps, S. and Hasnain, S. (2022). A novel role for interleukin-22 signaling in modulating mucosal epithelial cell antigen presentation machinery to control disease. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW), Sydney, NSW, Australia, 9–11 September 2022. Richmond, VIC, Australia: John Wiley & Sons. |
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2022 Journal Article MUC1 mediated macrophage activation promotes colitis-associated colorectal cancer via activating the IL-6/STAT3 axisSheng, Yong H., Davies, Julie M., Wang, Ran, Wong, Kuan Yau, Giri, Rabina, Yang, Yuanhao, Begun, Jakob, Florin, Timothy H., Hasnain, Sumaira Z. and McGuckin, Michael A. (2022). MUC1 mediated macrophage activation promotes colitis-associated colorectal cancer via activating the IL-6/STAT3 axis. Cellular and Molecular Gastroenterology and Hepatology, 14 (4), 789-811. doi: 10.1016/j.jcmgh.2022.06.010 |
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2022 Conference Publication Building a case for pancreas and liver targeted intereukin-22 therapy in fatty liver diseaseSajiir, Haressh, Wong, Kuan Yau, Mueller, Alexandra, Keshvari, Sahar, Wang, Ran, Wiid, Percival, Ramm, Grant, Macdonald, Graeme, Prins, John, McGuckin, Michael and Hasnain, Sumaira (2022). Building a case for pancreas and liver targeted intereukin-22 therapy in fatty liver disease. The International Liver Congress 2022, London, United Kingdom, 22-26 June 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/s0168-8278(22)00756-5 |
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2022 Conference Publication Building a case for liver and pancreas targeted interleukin-22 therapy for use in non-alcoholic fatty liver diseaseSajiir, Haressh, Wong, Kuanyau, Mueller, Alexander, Keshvari, Sahar, Wang, Ran, Macdonald, Graeme A., Prins, John, Mcguckin, Michael and Hasnain, Sumaira Z. (2022). Building a case for liver and pancreas targeted interleukin-22 therapy for use in non-alcoholic fatty liver disease. Digestive Disease Week 2022, San Diego, CA United States, 21-24 May 2022. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(22)60035-0 |
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2022 Conference Publication Pancreatic Interleukin-22 Receptor Signaling is Critical in Maintaining Beta-Cell Insulin Production and is HepatoprotectiveSajiir, Haressh, Wong, Kuan Yau, Mueller, Alexandra, Keshvari, Sahar, Wang, Ran, Wiid, Percival, Macdonald, Graeme, Prins, John, McGuckin, Michael A. and Hasnain, Sumaira Z. (2022). Pancreatic Interleukin-22 Receptor Signaling is Critical in Maintaining Beta-Cell Insulin Production and is Hepatoprotective. Immunology 2022 Meeting, Portland, OR United States, 6-10 May 2022. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.208.supp.46.08 |
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2022 Journal Article A novel role for Interleukin-22 in suppressing major histocompatibility complex II in mucosal epithelial cellsMoniruzzaman, Md, Rahman, M. Arifur, Wang, Ran, Wong, Kuan Yau, Chen, Alice C-H, Mueller, Alexandra, Taylor, Steven, Harding, Alexa, Illankoon, Thishan, Wiid, Percival, Sajiir, Haressh, Schreiber, Veronika, Martin, Megan L., Burr, Lucy D., McGuckin, Michael A., Phipps, Simon and Hasnain, Sumaira Zia (2022). A novel role for Interleukin-22 in suppressing major histocompatibility complex II in mucosal epithelial cells. SSRN Electronic Journal. doi: 10.2139/ssrn.4185134 |
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2021 Journal Article Genetic and pharmacological inhibition of the nuclear receptor RORα regulates TH17 driven inflammatory disordersWang, Ran, Campbell, Sean, Amir, Mohammed, Mosure, Sarah A., Bassette, Molly A., Eliason, Amber, Sundrud, Mark S., Kamenecka, Theodore M. and Solt, Laura A. (2021). Genetic and pharmacological inhibition of the nuclear receptor RORα regulates TH17 driven inflammatory disorders. Nature Communications, 12 (1) 76, 1-18. doi: 10.1038/s41467-020-20385-9 |
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2021 Journal Article Nanocarriers for oral delivery of biologics: small carriers for big payloadsCao, Yuxue, Rewatkar, Prarthana, Wang, Ran, Hasnain, Sumaira Z., Popat, Amirali and Kumeria, Tushar (2021). Nanocarriers for oral delivery of biologics: small carriers for big payloads. Trends in Pharmacological Sciences, 42 (11), 957-972. doi: 10.1016/j.tips.2021.08.005 |
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2021 Journal Article Gut microbiota shape the inflammatory response in mice with an epithelial defectWang, Ran, Moniruzzaman, Md, Wong, Kuan Yau, Wiid, Percival, Harding, Alexa, Giri, Rabina, Tong, Wendy Hui, Creagh, Jackie, Begun, Jakob, McGuckin, Michael A. and Hasnain, Sumaira Z. (2021). Gut microbiota shape the inflammatory response in mice with an epithelial defect. Gut microbes, 13 (1), 1-18. doi: 10.1080/19490976.2021.1887720 |
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2020 Journal Article Editorial: the response of mucosal epithelial cells to infectionsWang, Ran and Proud, David (2020). Editorial: the response of mucosal epithelial cells to infections. Frontiers in Cellular and Infection Microbiology, 10 602312, 602312. doi: 10.3389/fcimb.2020.602312 |
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2020 Journal Article Oral delivery of β-lactoglobulin nanospheres encapsulated resveratrol alleviates inflammation in Winnie mice with spontaneous ulcerative colitisPujara, Naisarg, Wong, Kuan Yau, Qu, Zhi, Wang, Ran, Moniruzzaman, Md., Rewatkar, Prarthana, Kumeria, Tushar, Ross, Benjamin P., McGuckin, Michael and Popat, Amirali (2020). Oral delivery of β-lactoglobulin nanospheres encapsulated resveratrol alleviates inflammation in Winnie mice with spontaneous ulcerative colitis. Molecular Pharmaceutics, 18 (2) acs.molpharmaceut.0c00048, 627-640. doi: 10.1021/acs.molpharmaceut.0c00048 |
