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2020

Conference Publication

Blocking endogenous IL-22 is associated with reduced viral load and improved lung pathology in respiratory viral infections

Wang, R., Moniruzzaman, M., Wang, K., Upham, J. W., McGuckin, M., Phipps, S. and Hasnain, S. Z. (2020). Blocking endogenous IL-22 is associated with reduced viral load and improved lung pathology in respiratory viral infections. International Conference of the American-Thoracic-Society (ATS), Online, 10 November 2020. New York, NY, United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6530

Blocking endogenous IL-22 is associated with reduced viral load and improved lung pathology in respiratory viral infections

2020

Conference Publication

Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection

Hasnain, S., Wang, R., Taylor, S., Wong, K. Y., Moniruzzaman, M., Upham, J., Spann, K., Mcguckin, M. A., Burr, L. and Phipps, S. (2020). Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13777

Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection

2019

Journal Article

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

Sheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019). MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, 38 (48), 7294-7310. doi: 10.1038/s41388-019-0951-y

MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity

2019

Journal Article

Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway

Moniruzzaman, Md., Wang, Ran, Jeet, Varinder, McGuckin, Michael A. and Hasnain, Sumaira Z. (2019). Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway. International Journal of Molecular Sciences, 20 (14) 3468, 3468. doi: 10.3390/ijms20143468

Interleukin (IL)-22 from IL-20 Subfamily of cytokines induces colonic epithelial cell proliferation predominantly through ERK1/2 pathway

2019

Conference Publication

Genetic and pharmacological modulation of RORα regulates TH17-driven inflammatory disorders

Solt, Laura A., Wang, Ran, Amir, Mohammed, Chaudhari, Sweena, Campbell, Sean, Bassette, Molly B., Eliason, Amber, Sundrud, Mark S. and Kamenecka, Theodore (2019). Genetic and pharmacological modulation of RORα regulates TH17-driven inflammatory disorders. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.68.11

Genetic and pharmacological modulation of RORα regulates TH17-driven inflammatory disorders

2019

Conference Publication

Interleukin-20 subfamily cytokines in controlling intestinal inflammation and epithelial barrier integrity

Moniruzzaman, M., Wang, R., Wong, K., Tong, H., McGuckin, M. and Hasnain, S. (2019). Interleukin-20 subfamily cytokines in controlling intestinal inflammation and epithelial barrier integrity. Congress of ECCO, Copenhagen, Denmark, 6-9 March 2019. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjy222.044

Interleukin-20 subfamily cytokines in controlling intestinal inflammation and epithelial barrier integrity

2019

Conference Publication

A novel role of IL-22 in regulating epithelial MHC molecule expression and antigen presentation during viral infection

Wang, R., Taylor, S., Moniruzzaman, M., Wong, K., Upham, J., Spann, K., McGuckin, M., Phipps, S. and Hasnain, S. (2019). A novel role of IL-22 in regulating epithelial MHC molecule expression and antigen presentation during viral infection. 17th International Congress of Immunology (IUIS), Beijing, People's Republic of China, 9-23 October 2019. Weinheim, Germany: Wiley.

A novel role of IL-22 in regulating epithelial MHC molecule expression and antigen presentation during viral infection

2018

Journal Article

REV-ERBα regulates T(H)17 cell development and autoimmunity

Amir, Mohammed, Chaudhari, Sweena, Wang, Ran, Campbell, Sean, Mosure, Sarah A., Chopp, Laura B., Lu, Qun, Shang, Jinsai, Pelletier, Oliver B., He, Yuanjun, Doebelin, Christelle, Cameron, Michael D., Kojetin, Douglas J., Kamenecka, Theodore M. and Solt, Laura A. (2018). REV-ERBα regulates T(H)17 cell development and autoimmunity. Cell Reports, 25 (13), 3733-+. doi: 10.1016/j.celrep.2018.11.101

REV-ERBα regulates T(H)17 cell development and autoimmunity

2018

Conference Publication

Interleukin-22: A potential therapy to control intestinal inflammation

Moniruzzaman, M., Wang, R., Wong, K. Y., Tong, H., McGuckin, M. A. and Hasnain, S. Z. (2018). Interleukin-22: A potential therapy to control intestinal inflammation. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “Gut Matters”, Brisbane, QLD, Australia, 8-10 September 2018. Richmond, VIC, Australia: John Wiley & Sons.

Interleukin-22: A potential therapy to control intestinal inflammation

2018

Conference Publication

Enteric microbiota shape the inflammatory response in mice with a Muc2 misfolding mutation

Wang, R., Giri, R., Moniruzzaman, M., Tong, H., Wong, K. Y., Begun, J., McGuckin, M. A. and Hasnain, S. Z. (2018). Enteric microbiota shape the inflammatory response in mice with a Muc2 misfolding mutation. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “Gut Matters”, Brisbane, QLD, Australia, 8-10 September 2018. Richmond, VIC, Australia: John Wiley & Sons.

Enteric microbiota shape the inflammatory response in mice with a Muc2 misfolding mutation

2018

Conference Publication

Ubiquitin Ligase MARCH8 attenuates Graft versus Host Disease via Regulation of Gut Epithelial Cell Surface MHC II Expression

Lineburg, Katie E., Le Texier, Laetitia, Melino, Michelle, Wang, Ran, Clouston, Andrew, Blazar, Bruce R., McGuckin, Michael A., Villadangos, Jose A., Mintern, Justine D. and MacDonald, Kelli P. A. (2018). Ubiquitin Ligase MARCH8 attenuates Graft versus Host Disease via Regulation of Gut Epithelial Cell Surface MHC II Expression. 27th International Congress of the Transplantation-Society (TTS), Madrid, Spain, 30 June - 5 July 2018. Philadelphia, PA, United States: Lippincott Williams & Wilkins. doi: 10.1097/01.tp.0000543013.84163.3a

Ubiquitin Ligase MARCH8 attenuates Graft versus Host Disease via Regulation of Gut Epithelial Cell Surface MHC II Expression

2018

Conference Publication

The REV-ERBs: Negative Regulators of Th17 Cell Development and Autoimmunity

Amir, Mohammed, Chaudhari, Sweena M., Wang, Ran, Campbell, Sean, Kamenecka, Theodore M. and Solt, Laura A. (2018). The REV-ERBs: Negative Regulators of Th17 Cell Development and Autoimmunity. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.163.10

The REV-ERBs: Negative Regulators of Th17 Cell Development and Autoimmunity

2018

Conference Publication

A non-redundant role for RORα in TH17 cell development and TH17-driven inflammatory disorders

Solt, Laura A., Wang, Ran, Amir, Mohammed, Chaudhari, Sweena M., Campbell, Sean, Bassette, Molly A. and Kamenecka, Theodore M. (2018). A non-redundant role for RORα in TH17 cell development and TH17-driven inflammatory disorders. Immunology 2018™ Meeting, Austin, TX United States, 4-8 May 2018. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.200.supp.121.3

A non-redundant role for RORα in TH17 cell development and TH17-driven inflammatory disorders

2018

Journal Article

Immune regulation of the unfolded protein response at the mucosal barrier in viral infection

Wang, Ran, Moniruzzaman, Md., Shuffle, Eric, Lourie, Rohan and Hasnain, Sumaira Z. (2018). Immune regulation of the unfolded protein response at the mucosal barrier in viral infection. Clinical & Translational Immunology, 7 (4) e1014, e1014. doi: 10.1002/cti2.1014

Immune regulation of the unfolded protein response at the mucosal barrier in viral infection

2017

Journal Article

The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse

Borg, Danielle J., Wang, Ran, Murray, Lydia, Tong, Hui, Steptoe, Raymond J., McGuckin, Michael A. and Hasnain, Sumaira Z. (2017). The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse. Diabetologia, 60 (11), 1-6. doi: 10.1007/s00125-017-4392-2

The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse

2017

Journal Article

Analyzing the properties of murine intestinal mucins by electrophoresis and histology

Wang, Ran and Hasnain, Sumaira Z. (2017). Analyzing the properties of murine intestinal mucins by electrophoresis and histology. Bio-protocol, 7 (14). doi: 10.21769/BioProtoc.2394

Analyzing the properties of murine intestinal mucins by electrophoresis and histology

2017

Conference Publication

Negative regulation of Th17 cell development and function by the REV-ERBs

Solt, Laura A, Amir, Mohammed, Chaudhari, Sweena M., Wang, Ran and Campbell, Sean (2017). Negative regulation of Th17 cell development and function by the REV-ERBs. Immunology 2017™ Meeting, Washington, DC United States, 12-16 May 2017. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.198.supp.127.15

Negative regulation of Th17 cell development and function by the REV-ERBs

2017

Conference Publication

Targeting interleukin-23(p19) secretion from intestinal epithelial cells to improve intestinal barrier integrity in inflammatory bowel disease

Wang, R., Lourie, R., Tong, H., Giri, R., Schreiber, V., Begun, J., Florin, T., McGuckin, M. A. and Hasnain, S. Z. (2017). Targeting interleukin-23(p19) secretion from intestinal epithelial cells to improve intestinal barrier integrity in inflammatory bowel disease. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, Gold Coast, QLD Australia, 20–22 August 2017. Richmond, VIC Australia: Wiley.

Targeting interleukin-23(p19) secretion from intestinal epithelial cells to improve intestinal barrier integrity in inflammatory bowel disease

2016

Journal Article

Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism

Oancea, I., Movva, R., Das, I., Aguirre de Carcer, D., Schreiber, V., Yang, Y., Purdon, A., Harrington, B., Proctor, M., Wang, R., Sheng, Y., Lobb, M., Lourie, R., Cuiv, P.O., Duley, J.A., Begun, J. and Florin, T.H.J. (2016). Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism. Gut, 66 (1), 59-69. doi: 10.1136/gutjnl-2015-310874

Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism

2016

Journal Article

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22

Gulhane, Max, Murray, Lydia, Lourie, Rohan, Tong, Hui, Sheng, Yong H., Wang, Ran, Kang, Alicia, Schreiber, Veronika, Wong, Kuan Yau, Magor, Graham, Denman, Stuart, Begun, Jakob, Florin, Timothy H., Perkins, Andrew, Cuiv, Paraic O., McGuckin, Michael A. and Hasnain, Sumaira Z. (2016). High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22. Scientific Reports, 6 (1) 28990, 28990. doi: 10.1038/srep28990

High fat diets induce colonic epithelial cell stress and inflammation that is reversed by IL-22