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2019

Journal Article

Complex multilevel control of hemolysin production by uropathogenic Escherichia coli

Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Forde, Brian M., Murthy, Ambika M. V., Peters, Kate M., Day, Christopher J., Poole, Jessica, Kidd, Timothy J., Welch, Rodney A., Jennings, Michael P., Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2019). Complex multilevel control of hemolysin production by uropathogenic Escherichia coli. mBio, 10 (5) e02248-19. doi: 10.1128/mbio.02248-19

Complex multilevel control of hemolysin production by uropathogenic Escherichia coli

2019

Journal Article

Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

Stocks, Claudia J., Phan, Minh-Duy, Achard, Maud E. S., Nhu, Nguyen Thi Khanh, Condon, Nicholas D., Gawthorne, Jayde A., Lo, Alvin W., Peters, Kate M., McEwan, Alastair G., Kapetanovic, Ronan, Schembri, Mark A. and Sweet, Matthew J. (2019). Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination. Proceedings of the National Academy of Sciences, 116 (13), 6341-6350. doi: 10.1073/pnas.1820870116

Uropathogenic Escherichia coli employs both evasion and resistance to subvert innate immune-mediated zinc toxicity for dissemination

2019

Journal Article

Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization

Murthy, Ambika M. V., Sullivan, Matthew J., Nhu, Nguyen Thi Khanh, Lo, Alvin W., Phan, Minh-Duy, Peters, Kate M., Boucher, Dave, Schroder, Kate, Beatson, Scott A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2019). Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization. FASEB Journal : official publication of the Federation of American Societies for Experimental Biology, 33 (6), fj201802100R-7450. doi: 10.1096/fj.201802100R

Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization

2019

Journal Article

Clinical and laboratory-induced colistin-resistance mechanisms in Acinetobacter baumannii

Boinett, Christine J., Cain, Amy K., Hawkey, Jane, Nhu Tran Do Hoang,, Nhu, Nguyen Thi Khanh Nhu, Pham, Thanh Duy, Dordel, Janina, Campbell, James, Nguyen Phu Huong Lan,, Mayho, Matthew, Langridge, Gemma C., Hadfield, James, Nguyen Van Vinh Chau,, Thwaites, Guy E., Parkhill, Julian, Thomson, Nicholas R., Holt, Kathryn E. and Baker, Stephen (2019). Clinical and laboratory-induced colistin-resistance mechanisms in Acinetobacter baumannii. Microbial Genomics, 5 (2) 000246. doi: 10.1099/mgen.0.000246

Clinical and laboratory-induced colistin-resistance mechanisms in Acinetobacter baumannii

2018

Journal Article

Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage

Nhu, Nguyen Thi Khanh, Phan, Minh-Duy, Peters, Kate M., Lo, Alvin W., Forde, Brian M., Min Chong, Teik, Yin, Wai-Fong, Chan, Kok-Gan, Chromek, Milan, Brauner, Annelie, Chapman, Matthew R., Beatson, Scott A. and Schembri, Mark A. (2018). Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage. mBio, 9 (4) e01462-18. doi: 10.1128/mbio.01462-18

Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage

2018

Other Outputs

Molecular and genomic analysis of multidrug resistant Uropathogenic Escherichia coli

Nguyen, Thi Khanh Nhu (2018). Molecular and genomic analysis of multidrug resistant Uropathogenic Escherichia coli. PhD Thesis, School of Chemistry and Molecular Biosciences, The University of Queensland. doi: 10.14264/uql.2018.462

Molecular and genomic analysis of multidrug resistant Uropathogenic Escherichia coli

2018

Journal Article

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages

Murthy, Ambika M. V., Phan, Minh-Duy, Peters, Kate M., Nhu, Nguyen Thi Khanh, Welch, Rodney A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2018). Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages. Virulence, 9 (1), 1-32. doi: 10.1080/21505594.2018.1465786

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages

2018

Journal Article

A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults

Mai, Nguyen T. H., Dobbs, Nicholas, Nguyen Hoan Phu, , Colas, Romain A., Thao, Le T. P., Thuong, Nguyen T. T., Nghia, Ho D. T., Hanh, Nguyen H. H., Hang, Nguyen T., Heemskerk, A. Dorothee, Day, Jeremy N., Ly, Lucy, Thu, Do D. A., Merson, Laura, Kestelyn, Evelyne, Wolbers, Marcel, Geskus, Ronald, Summers, David, Chau, Nguyen V. V., Dalli, Jesmond and Thwaites, Guy E. (2018). A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults. Elife, 7 e33478. doi: 10.7554/elife.33478

A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults

2018

Journal Article

A new rearranged abietane diterpene from <i>Clerodendrum inerme</i> with antioxidant and cytotoxic activities

Le Ba Vinh, , Nguyen Thi Minh Nguyet, , Yang, Seo Young, Kim, Jang Hoon, Le Thi Vien, , Phan Thi Thanh Huong, , Nguyen Van Thanh, , Nguyen Xuan Cuong, , Nguyen Hoai Nam, , Chau Van Minh, , Inkyu Hwang, and Kim, Young Ho (2018). A new rearranged abietane diterpene from Clerodendrum inerme with antioxidant and cytotoxic activities. Natural Product Research, 32 (17), 2001-2007. doi: 10.1080/14786419.2017.1360885

A new rearranged abietane diterpene from <i>Clerodendrum inerme</i> with antioxidant and cytotoxic activities

2017

Journal Article

Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli

Phan, Minh-Duy, Nhu, Nguyen Thi Khanh, Achard, Maud E. S., Forde, Brian M., Hong, Kar Wai, Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, West, Nicholas P., Walker, Mark J., Paterson, David L., Beatson, Scott A. and Schembri, Mark A. (2017). Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 72 (10), 2729-2736. doi: 10.1093/jac/dkx204

Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli

2017

Journal Article

Causes and outcomes of sepsis in southeast Asia: a multinational multicentre cross-sectional study

Sudarmono, Pratiwi, Aman, Abu Tholib, Arif, Mansyur, Syarif, Armaji Kamaludi, Kosasih, Herman, Karyana, Muhammad, Chotpitayasunondh, Tawee, Vandepitte, Warunee Punpanich, Boonyasiri, Adiratha, Lapphra, Keswadee, Chokephaibulkit, Kulkanya, Rattanaumpawan, Pinyo, Thamlikitkul, Visanu, Laongnualpanich, Achara, Teparrakkul, Prapit, Srisamang, Pramot, Phan Huu Phuc, , Le Thanh Hai, , Nguyen Van Kinh, , Bui Duc Phu, , Nguyen Thanh Hung, , Tang Chi Thuong, , Ha Manh Tuan, , Lam Minh Yen, , Nguyen Van Vinh Chau, , Limmathurotsakul, Direk, Thaipadungpanit, Janjira, Blacksell, Stuart, Day, Nicholas ... Lau, Chuen-Yen (2017). Causes and outcomes of sepsis in southeast Asia: a multinational multicentre cross-sectional study. Lancet Global Health, 5 (2), E157-E167.

Causes and outcomes of sepsis in southeast Asia: a multinational multicentre cross-sectional study

2016

Journal Article

Fluorescence-based flow sorting in parallel with transposon insertion site sequencing identifies multidrug efflux systems in Acinetobacter baumannii

Hassan, Karl A., Cain, Amy K., Huang, TaoTao, Liu, Qi, Elbourne, Liam D. H., Boinett, Christine J., Brzoska, Anthony J., Li, Liping, Ostrowski, Martin, Nhu, Nguyen Thi Khanh, Nhu, Tran Do Hoang, Baker, Stephen, Parkhill, Julian and Paulsen, Ian T. (2016). Fluorescence-based flow sorting in parallel with transposon insertion site sequencing identifies multidrug efflux systems in Acinetobacter baumannii. mBio, 7 (5) e01200-16. doi: 10.1128/mBio.01200-16

Fluorescence-based flow sorting in parallel with transposon insertion site sequencing identifies multidrug efflux systems in Acinetobacter baumannii

2016

Journal Article

Erratum for Ben Zakour et al., Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131

Ben Zakour, Nouri L, Alsheikh-Hussain, Areej S, Ashcroft, Melinda M, Khanh Nhu, Nguyen Thi, Roberts, Leah W, Stanton-Cook, Mitchell, Schembri, Mark A and Beatson, Scott A (2016). Erratum for Ben Zakour et al., Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131. mBio, 7 (3), 1-1. doi: 10.1128/mBio.00958-16

Erratum for Ben Zakour et al., Sequential Acquisition of Virulence and Fluoroquinolone Resistance Has Shaped the Evolution of Escherichia coli ST131

2016

Journal Article

The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications

Nhu, Nguyen Thi Khanh, Riordan, David W., Nhu, Tran Do Hoang, Thanh, Duy Pham, Thwaites, Guy, Lan, Nguyen Phu Huong, Wren, Brendan W., Baker, Stephen and Stabler, Richard A. (2016). The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications. Scientific Reports, 6 (1) 28291, 28291. doi: 10.1038/srep28291

The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications

2016

Journal Article

Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131

Ben Zakour, Nouri L., Alsheikh-Hussain, Areej S., Ashcroft, Melinda M., Nhu, Nguyen Thi Khanh, Roberts, Leah W., Stanton-Cook, Mitchell, Schembri, Mark A. and Beatson, Scott A. (2016). Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131. MBio, 7 (2) e00347-16, e00347-16.1-e00347-16.11. doi: 10.1128/mBio.00347-16

Sequential acquisition of virulence and fluoroquinolone resistance has shaped the evolution of Escherichia coli ST131

2016

Journal Article

Repeated local emergence of carbapenem-resistant Acinetobacter baumannii in a single hospital ward

Schultz, Mark B., Duy, Pham Thanh, Nhu, Tran Do Hoan, Wick, Ryan R., Ingle, Danielle J., Hawkey, Jane, Edwards, David J., Kenyon, Johanna J., Nguyen Phu Huong Lan,, Campbell, James I., Thwaites, Guy, Nguyen, Thi Khanh Nhu, Hall, Ruth M., Fournier-Level, Alexandre, Baker, Stephen and Holt, Kathryn E. (2016). Repeated local emergence of carbapenem-resistant Acinetobacter baumannii in a single hospital ward. Microbial Genomics, 2 (3) 50, 1-15. doi: 10.1099/mgen.0.000050

Repeated local emergence of carbapenem-resistant Acinetobacter baumannii in a single hospital ward

2015

Journal Article

Impact of a methadone maintenance therapy pilot in Vietnam and its role in a scaled-up response

Hoang, Tran Vu, Ha, Tran Thi Thanh, Hoang, Tran Minh, Nhu, Nguyen To, Quoc, Nguyen Cuong, Tam, Nguyen Thi Minh and Mills, Stephen (2015). Impact of a methadone maintenance therapy pilot in Vietnam and its role in a scaled-up response. Harm Reduction Journal, 12 (1) 39. doi: 10.1186/s12954-015-0075-9

Impact of a methadone maintenance therapy pilot in Vietnam and its role in a scaled-up response

2015

Journal Article

In vitro activity of colistin in antimicrobial combination against carbapenem-resistant acinetobacter baumannii isolated from patients with ventilator-associated pneumonia in Vietnam

Le Minh, Vien, Nhu, Nguyen Thi Khanh, Phat, Voong Vinh, Thompson, Corinne, Lan, Nguyen Phu Huong, Nga, Tran Vu Thieu, Tam, Pham Thi Thanh, Tuyen, Ha Thanh, Nhu, Tran Do Hoang, Van Hao, Nguyen, Loan, Huynh Thi, Yen, Lam Minh, Parry, Christopher M., Nghia, Ho Dang Trung, Campbell, James I., Hien, Tran Tinh, Thwaites, Louise, Thwaites, Guy, Van Vinh Chau, Nguyen and Baker, Stephen (2015). In vitro activity of colistin in antimicrobial combination against carbapenem-resistant acinetobacter baumannii isolated from patients with ventilator-associated pneumonia in Vietnam. Journal of Medical Microbiology, 64 (10), 1162-1169. doi: 10.1099/jmm.0.000137

In vitro activity of colistin in antimicrobial combination against carbapenem-resistant acinetobacter baumannii isolated from patients with ventilator-associated pneumonia in Vietnam

2015

Journal Article

Genetic characterization of three qnrS1-harbouring multidrug-resistance plasmids and qnrS1-containing transposons circulating in Ho Chi Minh City, Vietnam

Le, Vien., Nhu, Nguyen Thi Khanh., Cerdeno-Tarraga, Ana., Campbell, James I., Tuyen, Ha Thanh., Nhu, Tran Do Hoang., Tam, Pham Thi Thanh., Schultsz, Constance., Thwaites, Guy., Thomson, Nicholas R. and Baker, Stephen (2015). Genetic characterization of three qnrS1-harbouring multidrug-resistance plasmids and qnrS1-containing transposons circulating in Ho Chi Minh City, Vietnam. Journal of Medical Microbiology, 64 (8) 000100, 869-878. doi: 10.1099/jmm.0.000100

Genetic characterization of three qnrS1-harbouring multidrug-resistance plasmids and qnrS1-containing transposons circulating in Ho Chi Minh City, Vietnam

2015

Journal Article

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

Holt, Kathryn E., Wertheim, Heiman, Zadoks, Ruth N., Baker, Stephen, Whitehouse, Chris A., Dance, David, Jenney, Adam, Connor, Thomas R., Hsu, Li Yang, Severin, Juliette, Brisse, Sylvain, Cao, Hanwei, Wilksch, Jonathan, Gorrie, Claire, Schultz, Mark B., Edwards, David J., Van Nguyen, Kinh, Nguyen, Trung Vu, Dao, Trinh Tuyet, Mensink, Martijn, Le Minh, Vien, Nhu, Nguyen Thi Khanh, Schultsz, Constance, Kuntaman K., Newton P.N., Moore C.E., Strugnell R.A. and Thomson N.R. (2015). Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health. Proceedings of the National Academy of Sciences of the United States of America, 112 (27), E3574-E3581. doi: 10.1073/pnas.1501049112

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health