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2012

Journal Article

Structure aided design of chimeric antibiotics

Karoli, Tomislav, Mamidyala, Sreeman K., Zuegg, Johannes, Fry, Scott R., Tee, Ernest H. L., Bradford, Tanya A., Madala, Praveen K., Huang, Johnny X., Ramu, Soumya, Butler, Mark S. and Cooper, Matthew A. (2012). Structure aided design of chimeric antibiotics. Bioorganic & Medicinal Chemistry Letters, 22 (7), 2428-2433. doi: 10.1016/j.bmcl.2012.02.019

Structure aided design of chimeric antibiotics

2011

Journal Article

The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II

Jia, ZhiGuang, O'Mara, Megan L., Zuegg, Johannes, Cooper, Matthew A. and Mark, Alan E. (2011). The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II. Biophysical Journal, 101 (11), 2684-2692. doi: 10.1016/j.bpj.2011.10.047

The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II

2011

Conference Publication

Membrane binding and perturbation studies of the antimicrobial peptides caerin, citropin and maculatin

Chia, C. S. Brian, Gong, Yujing, Bowie, John H., Zuegg, Johannes and Cooper, Matthew A. (2011). Membrane binding and perturbation studies of the antimicrobial peptides caerin, citropin and maculatin. New York, NY, U.S.A.: John Wiley & Sons. doi: 10.1002/bip.21438

Membrane binding and perturbation studies of the antimicrobial peptides caerin, citropin and maculatin

2010

Journal Article

Biological diversity from a structurally diverse library: Systematically scanning conformational space using a pyranose scaffold

Abbenante, Giovanni, Becker, Bernd, Blanc, Sebastien, Clark, Chris, Condie, Glenn, Fraser, Graeme, Grathwohl, Matthias, Halliday, Judy, Henderson, Senka, Lam, Ann, Liu, Ligong, Mann, Maretta, Muldoon, Craig, Pearson, Andrew, Premraj, Rajaratnam, Ramsdale, Tracie, Rossetti, Tony, Schafer, Karl, Le Thanh, Giang, Tometzki, Gerald, Vari, Frank, Verquin, Geraldine, Waanders, Jennifer, West, Michael, Wimmer, Norbert, Yau, Annika, Zuegg, Johannes and Meutermans, Wim (2010). Biological diversity from a structurally diverse library: Systematically scanning conformational space using a pyranose scaffold. Journal of Medicinal Chemistry, 53 (15), 5576-5586. doi: 10.1021/jm1002777

Biological diversity from a structurally diverse library: Systematically scanning conformational space using a pyranose scaffold

2010

Journal Article

A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds

Thanh, Giang Le, Abbenante, Giovanni, Adamson, George, Becker, Bernd, Clark, Chris, Condie, Glenn, Falzun, Tania, Grathwohl, Matthias, Gupta, Praveer, Hanson, Michael, Huynh, Ngoc, Katavic, Peter, Kuipers, Krystle, Lam, Ann, Liu, Ligong, Mann, Maretta, Mason, Jeff, McKeveney, Declan, Muldoon, Craig, Pearson, Andrew, Rajaratnam, Premraj, Ryan, Sarah, Tometzki, Gerry, Verquin, Geraldine, Waanders, Jennifer, West, Michael, Wilcox, Neil, Wimmer, Norbert, Yau, Annika ... Meutermans, Wim (2010). A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds. Journal of Organic Chemistry, 75 (1), 197-203. doi: 10.1021/jo9021919

A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds

2008

Other Outputs

Selective Inhibitors

Tometzki, Gerald B., Meutermans, Wim, Becker, Bernd, Zuegg, Johannes, Premraj, Rajaratnam, Muldoon, Craig, Mckeveney, Declan and Condie, Glenn (2008). Selective Inhibitors. US 20080009418.

Selective Inhibitors

2007

Journal Article

Crystal structures of the PBP2 glycosyltransferase domain: For antibacterial drug design new opportunities

Zuegg, Johannes and Meutermans, Wim (2007). Crystal structures of the PBP2 glycosyltransferase domain: For antibacterial drug design new opportunities. Chemmedchem, 2 (10), 1403-1404. doi: 10.1002/cmdc.200700114

Crystal structures of the PBP2 glycosyltransferase domain: For antibacterial drug design new opportunities

2007

Other Outputs

Monosaccharide compounds as antibacterial agents and their preparation and use in the treatment of diseases

Meutermans, Wim, Mckeveney, Declan, Zuegg, Johannes, Premraj, Rajaratnam, Muldoon, Craig and Le Thanh, Giang (2007). Monosaccharide compounds as antibacterial agents and their preparation and use in the treatment of diseases.

Monosaccharide compounds as antibacterial agents and their preparation and use in the treatment of diseases

2006

Other Outputs

Selective inhibitors

Becker, Bernd, Condie, Glenn, Christopher, McKeveney, Declan, Meutermans, Wim, Muldoon, Craig, Premraj, Rajaratnam and Zuegg, Johannes (2006). Selective inhibitors. WO/2006/037159; PCT/AU2005/001510.

Selective inhibitors

2005

Other Outputs

Biologically active compounds with with anti-angiogenic properties

Becker, Bernd, Condie, Glenn, Halliday, Judy, McKeveney, Declan, Meutermans, Wim, Muldoon, Craig, Premraj, Rajaratnam, Ramsdale, Tracie Elizabeth, Tometzki, Gerald and Zuegg, Johannes (2005). Biologically active compounds with with anti-angiogenic properties. WO/2005/097142; PCT/AU2005/000506.

Biologically active compounds with with anti-angiogenic properties

2004

Journal Article

A probabilistic measure for alignment-free sequence comparison

Pham T.D. and Zuegg J. (2004). A probabilistic measure for alignment-free sequence comparison. Bioinformatics, 20 (18), 3455-3461. doi: 10.1093/bioinformatics/bth426

A probabilistic measure for alignment-free sequence comparison

2003

Journal Article

Comparison of electrostatic potential around proteins calculated from Amber and AM1 charges: application to mutants of prion protein

Zuegg, J, Bliznyuk, AA and Gready, JE (2003). Comparison of electrostatic potential around proteins calculated from Amber and AM1 charges: application to mutants of prion protein. Molecular Physics, 101 (15), 2437-2450. doi: 10.1080/00268970310001592737

Comparison of electrostatic potential around proteins calculated from Amber and AM1 charges: application to mutants of prion protein

2003

Journal Article

Molecular diversity through sugar scaffolds

Le, GT, Abbenante, G, Becker, B, Grathwohl, M, Halliday, J, Tometzki, G, Zuegg, J and Meutermans, W (2003). Molecular diversity through sugar scaffolds. Drug Discovery Today, 8 (15), 701-709. doi: 10.1016/S1359-6446(03)02751-X

Molecular diversity through sugar scaffolds

2001

Conference Publication

Carbohydrate-based combinatorial libraries for the discovery of new antibacterial agents

Adamson, G, Schafer, K, Louis, L, Tometzki, G, Le Thanh, G, Schliebs, D, West, M, Zuegg, J, Halliday, J and Meutermans, W (2001). Carbohydrate-based combinatorial libraries for the discovery of new antibacterial agents. CARY: OXFORD UNIV PRESS INC.

Carbohydrate-based combinatorial libraries for the discovery of new antibacterial agents

2001

Journal Article

Structural model of human IL-13 defines the spatial interactions with the IL-13Rα/IL-4Rα receptor

Zuegg, J., Webb, D. C., Foster, P. S. and Casarotto, M. G. (2001). Structural model of human IL-13 defines the spatial interactions with the IL-13Rα/IL-4Rα receptor. Immunology and Cell Biology, 79 (4), 332-339. doi: 10.1046/j.1440-1711.2001.01035.x

Structural model of human IL-13 defines the spatial interactions with the IL-13Rα/IL-4Rα receptor

2000

Journal Article

Identification of active-site residues of the pro-metastatic endoglycosidase heparanase

Hulett M.D., Hornby J.R., Ohms S.J., Zuegg J., Freeman C., Gready J.E. and Parish C.R. (2000). Identification of active-site residues of the pro-metastatic endoglycosidase heparanase. Biochemistry, 39 (51), 15659-15667. doi: 10.1021/bi002080p

Identification of active-site residues of the pro-metastatic endoglycosidase heparanase

2000

Journal Article

Molecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor

Zuegg, J and Gready, JE (2000). Molecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor. Glycobiology, 10 (10), 959-974. doi: 10.1093/glycob/10.10.959

Molecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor

1999

Journal Article

Molecular dynamics simulations of human prion protein: Importance of correct treatment of electrostatic interactions

Zuegg J. and Gready J.E. (1999). Molecular dynamics simulations of human prion protein: Importance of correct treatment of electrostatic interactions. Biochemistry, 38 (42), 13862-13876. doi: 10.1021/bi991469d

Molecular dynamics simulations of human prion protein: Importance of correct treatment of electrostatic interactions

1999

Journal Article

Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis

Zuegg, J, Gruber, K, Gugganig, M, Wagner, UG and Kratky, C (1999). Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis. Protein Science, 8 (10), 1990-2000. doi: 10.1110/ps.8.10.1990

Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis

1997

Journal Article

Selectivity of lipases: Conformational analysis of suggested intermediates in ester hydrolysis of chiral primary and secondary alcohols

Zuegg J., Honig H., Schrag J.D. and Cygler M. (1997). Selectivity of lipases: Conformational analysis of suggested intermediates in ester hydrolysis of chiral primary and secondary alcohols. Journal of Molecular Catalysis - B Enzymatic, 3 (1-4), 83-98. doi: 10.1016/S1381-1177(96)00060-4

Selectivity of lipases: Conformational analysis of suggested intermediates in ester hydrolysis of chiral primary and secondary alcohols