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2020 Journal Article Multi-institution research and education collaboration identifies new antimicrobial compoundsFuller, Amelia A., Dounay, Amy B., Schirch, Douglas, Rivera, Daniel G., Hansford, Karl A., Elliott, Alysha G., Zuegg, Johannes, Cooper, Matthew A., Blaskovich, Mark A. T., Hitchens, Jacob R., Burris-Hiday, Sarah, Tenorio, Kristiana, Mendez, Yanira, Samaritoni, J. Geno, O’Donnell, Martin J. and Scott, William L. (2020). Multi-institution research and education collaboration identifies new antimicrobial compounds. ACS Chemical Biology, 15 (12), 3187-3196. doi: 10.1021/acschembio.0c00732 |
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2020 Journal Article α-Iodonitroalkenes as potential antifungal and antitubercular agentsPamarthi, Rambabu, Kumar, Ram, Sankara, Chennikkayala Siva, Lowe, Gabrielle J., Zuegg, Johannes, Singh, Sudheer Kumar and Ganesh, Madhu (2020). α-Iodonitroalkenes as potential antifungal and antitubercular agents. ChemistrySelect, 5 (39), 12272-12277. doi: 10.1002/slct.202003251 |
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2020 Journal Article Synthesis, antibacterial and antifungal activity of new 3-biphenyl-3H-Imidazo[1,2-a]azepin-1-ium bromidesDemchenko, Sergii, Lesyk, Roman, Zuegg, Johannes, Elliott, Alysha G., Fedchenkova, Yuliia, Suvorova, Zinaida and Demchenko, Anatolii (2020). Synthesis, antibacterial and antifungal activity of new 3-biphenyl-3H-Imidazo[1,2-a]azepin-1-ium bromides. European Journal of Medicinal Chemistry, 201 112477, 112477. doi: 10.1016/j.ejmech.2020.112477 |
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2020 Other Outputs Non-toxic Cobalt(III) Schiff Base Complexes with Broad Spectrum Antifungal ActivityFrei, Angelo, King, A. Paden, Lowe, Gabrielle J., Cain, Amy K., Short, Francesca L., Dinh, Hue, Elliott, Alysha, Zuegg, Johannes, Wilson, Justin J. and Blaskovich, Mark (2020). Non-toxic Cobalt(III) Schiff Base Complexes with Broad Spectrum Antifungal Activity. doi: 10.26434/chemrxiv.12736505.v1 |
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2020 Journal Article An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteriaElliott, Alysha G., Huang, Johnny X., Neve, Søren, Zuegg, Johannes, Edwards, Ingrid A., Cain, Amy K., Boinett, Christine J., Barquist, Lars, Lundberg, Carina Vingsbo, Steen, Jason, Butler, Mark S., Mobli, Mehdi, Porter, Kaela M., Blaskovich, Mark A. T., Lociuro, Sergio, Strandh, Magnus and Cooper, Matthew A. (2020). An amphipathic peptide with antibiotic activity against multidrug-resistant Gram-negative bacteria. Nature Communications, 11 (1) 3184, 3184. doi: 10.1038/s41467-020-16950-x |
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2020 Journal Article How to stimulate and facilitate early stage antibiotic discoveryZuegg, Johannes, Hansford, Karl A., Elliott, Alysha G., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). How to stimulate and facilitate early stage antibiotic discovery. ACS Infectious Diseases, 6 (6), 1302-1304. doi: 10.1021/acsinfecdis.0c00163 |
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2020 Journal Article Correction: Metal complexes as a promising source for new antibiotics (vol 11, pg 2627, 2020)Frei, Angelo, Zuegg, Johannes, Elliott, Alysha G., Baker, Murray, Braese, Stefan, Brown, Christopher, Chen, Feng, Dowson, Christopher G., Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour, Ahmed M., Massi, Massimiliano, Moat, John, Mohamed, Heba A., Renfrew, Anna K., Rutledge, Peter J., Sadler, Peter J., Todd, Matthew H., Willans, Charlotte E., Wilson, Justin J., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). Correction: Metal complexes as a promising source for new antibiotics (vol 11, pg 2627, 2020). Chemical Science, 11 (17), 4531-4531. doi: 10.1039/d0sc90075c |
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2020 Journal Article Discovery of cephalosporin-3′-diazeniumdiolates that show dual antibacterial and antibiofilm effects against Pseudomonas aeruginosa clinical cystic fibrosis isolates and efficacy in a murine respiratory infection modelRineh, Ardeshir, Soren, Odel, McEwan, Timothy, Ravikumar, Vikashini, Poh, Wee Han, Azamifar, Fereshteh, Naimi-Jamal, M. Reza, Cheung, Chen-Yi, Elliott, Alysha G., Zuegg, Johannes, Blaskovich, Mark A. T., Cooper, Matthew A., Dolange, Victoria, Christodoulides, Myron, Cook, Gregory M., Rice, Scott A., Faust, Saul N., Webb, Jeremy S. and Kelso, Michael J. (2020). Discovery of cephalosporin-3′-diazeniumdiolates that show dual antibacterial and antibiofilm effects against Pseudomonas aeruginosa clinical cystic fibrosis isolates and efficacy in a murine respiratory infection model. ACS Infectious Diseases, 6 (6) acsinfecdis.0c00070, 1460-1479. doi: 10.1021/acsinfecdis.0c00070 |
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2020 Journal Article Metal complexes as a promising source for new antibioticsFrei, Angelo, Zuegg, Johannes, Elliott, Alysha G., Baker, Murray V., Braese, Stefan, Brown, Christopher, Chen, Feng, Dowson, Christopher Gerard, Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour, Ahmed Moustafa, Massi, Massimiliano, Moat, John, Mohamed, Heba A., Renfrew, Anna, Rutledge, Peter, Sadler, Peter J., Todd, Matthew Houghton, Willans, Charlotte E., Wilson, Justin Jeff, Cooper, Matthew Allister and Blaskovich, Mark (2020). Metal complexes as a promising source for new antibiotics. Chemical Science, 11 (10), 2627-2639. doi: 10.1039/c9sc06460e |
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2020 Journal Article Hydroxyl substituted benzoic acid/cinnamic acid derivatives: tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studiesNazir, Yasir, Saeed, Aamer, Rafiq, Muhammad, Afzal, Samina, Ali, Anser, Latif, Muhammad, Zuegg, Johannes, Hussein, Waleed M., Fercher, Christian, Barnard, Ross T., Cooper, Matthew A., Blaskovich, Mark A.T., Ashraf, Zaman and Ziora, Zyta M. (2020). Hydroxyl substituted benzoic acid/cinnamic acid derivatives: tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies. Bioorganic and Medicinal Chemistry Letters, 30 (1) 126722, 1-5. doi: 10.1016/j.bmcl.2019.126722 |
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2019 Other Outputs Metal Complexes as a Promising Source for New AntibioticsFrei, Angelo, Zuegg, Johannes, Elliott, Alysha, Baker, Murray, Bräse, Stefan, Brown, Christopher, Chen, Feng, Dowson, Christopher, Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour, Ahmed, Massi, Massimiliano, Moat, John, Mohamed, Heba, Renfrew, Anna, Rutledge, Peter J., Sadler, Peter J., Todd, Matthew, Willans, Charlotte E., Wilson, Justin J., Cooper, Matthew and A. T. Blaskovich, Mark (2019). Metal Complexes as a Promising Source for New Antibiotics. doi: 10.26434/chemrxiv.9956744.v2 |
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2019 Other Outputs Metal Complexes as a Promising Source for New AntibioticsFrei, Angelo, Zuegg, Johannes, Elliott, Alysha, Baker, Murray, Bräse, Stefan, Brown, Christopher, Chen, Feng, Dowson, Christopher, Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour, Ahmed, Massi, Massimiliano, Moat, John, Mohamed, Heba, Renfrew, Anna, Rutledge, Peter J., Sadler, Peter J., Todd, Matthew, Willans, Charlotte E., Wilson, Justin J., Cooper, Matthew and A. T. Blaskovich, Mark (2019). Metal Complexes as a Promising Source for New Antibiotics. doi: 10.26434/chemrxiv.9956744.v1 |
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2019 Journal Article R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangiomaOverman, Jeroen, Fontaine, Frank, Wylie-Sears, Jill, Moustaqil, Mehdi, Huang, Lan, Meurer, Marie, Chiang, Ivy Kim, Lesieur, Emmanuelle, Patel, Jatin, Zuegg, Johannes, Pasquier, Eddy, Sierecki, Emma, Gambin, Yann, Hamdan, Mohamed, Khosrotehrani, Kiarash, Andelfinger, Gregor, Bischoff, Joyce and Francois, Mathias (2019). R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma. eLife, 8 e43026. doi: 10.7554/elife.43026 |
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2019 Journal Article Highly regio- and diastereoselective [3 + 2]-cycloadditions involving indolediones and α,β-disubstituted nitroethylenesRao, Madhuri P., Gunaga, Shubha S., Zuegg, Johannes, Pamarthi, Rambabu and Ganesh, Madhu (2019). Highly regio- and diastereoselective [3 + 2]-cycloadditions involving indolediones and α,β-disubstituted nitroethylenes. Organic and Biomolecular Chemistry, 17 (42), 9390-9402. doi: 10.1039/c9ob01429b |
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2018 Journal Article Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approachFontaine, Frank R., Goodall, Stephen, Prokop, Jeremy W., Howard, Christopher B., Moustaqil, Mehdi, Kumble, Sumukh, Rasicci, Daniel T., Osborne, Geoffrey W., Gambin, Yann, Sierecki, Emma, Jones, Martina L., Zuegg, Johannes, Mahler, Stephen and Francois, Mathias (2018). Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach. mAbs, 10 (4), 1-11. doi: 10.1080/19420862.2018.1451288 |
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2018 Journal Article Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteriaBlaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w |
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2017 Other Outputs Inhibitors of SOX 18 protein activity for treating angiogenesis- and/or lymphangiogenesisFrancois, Mathias, Zuegg, Johannes, Overman, Jeroen, Mamidyala, Sreeman Kumar, Salim, Angela Aguslyarti, Fontaine, Frank Roger, Cooper, Matthew Allister, Capon, Robert John and Robertson, Avril Alexis Barbara (2017). Inhibitors of SOX 18 protein activity for treating angiogenesis- and/or lymphangiogenesis. WO2018112545. |
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2017 Journal Article An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeuticsScott, Fraser J., Nichol, Ryan J. O., Khalaf, Abedawn I., Giordani, Federica, Gillingwater, Kirsten, Ramu, Soumya, Elliott, Alysha, Zuegg, Johannes, Duffy, Paula, Rosslee, Michael-Jon, Hlaka, Lerato, Kumar, Santosh, Ozturk, Mumin, Brombacher, Frank, Barrett, Michael, Guler, Reto and Suckling, Colin J. (2017). An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeutics. European Journal of Medicinal Chemistry, 136, 561-572. doi: 10.1016/j.ejmech.2017.05.039 |
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2017 Journal Article Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungalsDesselle, Mathilde R., Neale, Ruth, Hansford, Karl A., Zuegg, Johannes, Elliott, Alysha G., Cooper, Matthew A. and Blaskovich, Mark A. T. (2017). Institutional profile: Community for Open Antimicrobial Drug Discovery - crowdsourcing new antibiotics and antifungals. Future Science OA, 3 (2) FSO171, FSO171. doi: 10.4155/fsoa-2016-0093 |
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2017 Journal Article Small-molecule inhibitors of the SOX18 transcription factorFontaine, Frank, Overman, Jeroen, Moustaqil, Mehdi, Mamidyala, Sreeman, Salim, Angela, Narasimhan, Kamesh, Prokoph, Nina, Robertson, Avril A. B., Lua, Linda, Alexandrov, Kirill, Koopman, Peter, Capon, Robert J., Sierecki, Emma, Gambin, Yann, Jauch, Ralf, Cooper, Matthew A., Zuegg, Johannes and Francois, Mathias (2017). Small-molecule inhibitors of the SOX18 transcription factor. Chemistry Chemical Biology, 24 (3), 346-359. doi: 10.1016/j.chembiol.2017.01.003 |
