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2026 Journal Article Systemic C-reactive protein and vitamin D are not associated with development of chronic musculoskeletal pain over a 2–7 year follow-up periodCollyer, Martin R., Sterling, Michele, Armfield, Nigel R., Xie, Yanfei, Cabot, Peter J., Elphinston, Rachel A., Klyne, David M. and Farrell, Scott F. (2026). Systemic C-reactive protein and vitamin D are not associated with development of chronic musculoskeletal pain over a 2–7 year follow-up period. The Journal of Pain, 44 106297, 1-12. doi: 10.1016/j.jpain.2026.106297 |
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2026 Journal Article Time to wake up to the potential benefits of targeting sleep in osteoarthritis managementHall, Michelle, Ferreira, Paulo, Eyles, Jillian, Hawker, Gillian, Smith, Simon S., Egorova-Brumley, Natalia, McCurry, Susan M., Thorlund, Jonas B. and Klyne, David M (2026). Time to wake up to the potential benefits of targeting sleep in osteoarthritis management. Osteoarthritis and Cartilage, 34 (6), 776-783. doi: 10.1016/j.joca.2026.03.122 |
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2026 Journal Article Biomimetic MCC950-loaded cerium-layered double hydroxide nanoparticles for targeted treatment of Type 1 diabetes in streptozotocin-induced micePang, Huiwen, Chen, Zhuo, Wu, Youzhi, Nguyen, Thanh-Truc, Wang, Jingjing, Klyne, David M., Xu, Zhi Ping, Chen, Chen, Rowan, Alan and Han, Felicity Y. (2026). Biomimetic MCC950-loaded cerium-layered double hydroxide nanoparticles for targeted treatment of Type 1 diabetes in streptozotocin-induced mice. British Journal of Pharmacology bph.70451. doi: 10.1111/bph.70451 |
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2026 Journal Article Changes in sleep and clinical outcomes in hip osteoarthritis: a longitudinal secondary analysis of a randomised controlled trialZhang, Hanzhi, Dobson, Fiona, Allison, Kim, Knox, Gabrielle, Spiers, Libby, Egorova-Brumley, Natalia, Klyne, David M., Ferreira, Paulo and Hall, Michelle (2026). Changes in sleep and clinical outcomes in hip osteoarthritis: a longitudinal secondary analysis of a randomised controlled trial. Osteoarthritis and Cartilage Open, 8 (3) 100813, 100813. doi: 10.1016/j.ocarto.2026.100813 |
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2026 Journal Article Neuroimmune pathways linking sleep disturbance to persistent pain after injury are mitigated by exerciseKlyne, David M., Van Der Bas, Megan, Harris, Michele Y., Hilliard, Brendan A., Patel, Parth R., Kegg, Abby, Rajpal, Astha, Ceasar, Khyleisha, Kalicharan, Betsy A., Hodges, Paul W. and Barbe, Mary F. (2026). Neuroimmune pathways linking sleep disturbance to persistent pain after injury are mitigated by exercise. Pain. doi: 10.1097/j.pain.0000000000003978 |
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2026 Journal Article EFFECTS OF ADDING AEROBIC PHYSICAL ACTIVITY TO RESISTANCE EXERCISE ON EXPLORATORY OUTCOMES AND THEIR MEDIATING ROLE IN PEOPLE WITH HIP OSTEOARTHRITISWang, Michelle, Dobson, Fiona, Klyne, David, Ferreira, Paulo, Allison, Kim, Knox, Gabrielle, Hinman, Rana, Bennell, Kim, Spiers, Libby and Hall, Michelle (2026). EFFECTS OF ADDING AEROBIC PHYSICAL ACTIVITY TO RESISTANCE EXERCISE ON EXPLORATORY OUTCOMES AND THEIR MEDIATING ROLE IN PEOPLE WITH HIP OSTEOARTHRITIS. Osteoarthritis and Cartilage, 34, S399-S400. doi: 10.1016/j.joca.2026.01.583 |
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2026 Journal Article Pain and the immune systemHodges, Paul W., Fiore, Nathan T., Watkins, Linda R., Klyne, David M., Coppieters, Michel W. and Grace, Peter M. (2026). Pain and the immune system. Musculoskeletal Science and Practice, 82 103484, 1-14. doi: 10.1016/j.msksp.2025.103484 |
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2026 Journal Article PHYSIOTHERAPISTS’ PERCEPTIONS AND ATTITUDES TOWARD TRAINING IN COGNITIVE BEHAVIOURAL THERAPY FOR INSOMNIA (CBT-I)Wang, Michelle, Eyles, Jillian P., Bunzli, Samantha, Klyne, David, McCurry, Susan, Lawford, Belinda, Dinh, Amanda, Schütze, Rob, Nguyen, Alan, Rhon, Daniel I., Hinman, Rana, Smith, Simon, Window, Peter, Grealis, Stacey and Hall, Michelle (2026). PHYSIOTHERAPISTS’ PERCEPTIONS AND ATTITUDES TOWARD TRAINING IN COGNITIVE BEHAVIOURAL THERAPY FOR INSOMNIA (CBT-I). Osteoarthritis and Cartilage, 34, S177. doi: 10.1016/j.joca.2026.01.234 |
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2026 Journal Article Improved sleep is associated with improved hip osteoarthritis symptoms: a longitudinal studyZhang, Hanzhi, Dobson, Fiona, Allison, Kim, Knox, Gabrielle, Spiers, Libby, Brumley, Natalia E., Klyne, David, Ferreira, Paulo and Hall, Michelle (2026). Improved sleep is associated with improved hip osteoarthritis symptoms: a longitudinal study. Osteoarthritis and Cartilage, 34, S390. doi: 10.1016/j.joca.2026.01.565 |
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2026 Journal Article Understanding the relationship between sleep, psychological and musculoskeletal health from a neuroimmune perspectiveKlyne, David M., Hall, Michelle, Smith, Simon S., Barbe, Mary F., Egorova-Brumley, Natalia, Serafimovska, Anastasia, Hodges, Paul W. and Suraev, Anastasia (2026). Understanding the relationship between sleep, psychological and musculoskeletal health from a neuroimmune perspective. Musculoskeletal Science and Practice, 82 103509, 1-12. doi: 10.1016/j.msksp.2026.103509 |
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2026 Journal Article ASSOCIATIONS BETWEEN INSOMNIA AND TOTAL JOINT REPLACEMENT IN ADULTS WITH HIP (41,737) OR KNEE PAIN (81,958): A UK BIOBANK STUDYHaber, Travis S., Dyer, Brett, Klyne, David, Ferreira, Paulo, Nicolson, Philippa J., Lawford, Belinda, McCurry, Susan and Hall, Michelle (2026). ASSOCIATIONS BETWEEN INSOMNIA AND TOTAL JOINT REPLACEMENT IN ADULTS WITH HIP (41,737) OR KNEE PAIN (81,958): A UK BIOBANK STUDY. Osteoarthritis and Cartilage, 34, S105-S106. doi: 10.1016/j.joca.2026.01.121 |
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2026 Journal Article A Phase III triple-blind randomised placebo-controlled trial to evaluate effectiveness of early treatment with pregabalin to reduce pain severity after whiplash road traffic injury: study protocol for the PRioRTI Trial {1}Sterling, Michele, Farrell, Scott F., Ferguson, Lisa, Mitchell, Geoffrey, Schug, Stephan, Ware, Robert S., Dinh, Michael, Celenza, Antonio, Connelly, Luke, Hodges, Paul W., Klyne, David M., Elphinston, Rachel, Nikles, Jane, McAuley, James and Lin, Chung-Wei Christine (2026). A Phase III triple-blind randomised placebo-controlled trial to evaluate effectiveness of early treatment with pregabalin to reduce pain severity after whiplash road traffic injury: study protocol for the PRioRTI Trial {1}. Trials, 27 (1) 186, 1-13. doi: 10.1186/s13063-026-09479-9 |
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2026 Journal Article Neuroimmune interactions in musculoskeletal conditions. An introduction for cliniciansLutke Schipholt, Ivo J., Coppieters, Michel W., Scholten-Peeters, Gwendolyne G.M., Hutchinson, Mark R. and Klyne, David M. (2026). Neuroimmune interactions in musculoskeletal conditions. An introduction for clinicians. Musculoskeletal Science and Practice, 81 103469. doi: 10.1016/j.msksp.2025.103469 |
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2026 Journal Article Insomnia and progression to total joint replacement in hip (41 737) and knee pain (81 958): a prospective UK biobank cohort studyHaber, Travis, Dyer, Brett, Klyne, David M., Ferreira, Paulo H., Nicolson, Philippa J A, Lawford, Belinda J., McCurry, Susan M. and Hall, Michelle (2026). Insomnia and progression to total joint replacement in hip (41 737) and knee pain (81 958): a prospective UK biobank cohort study. RMD Open, 12 (1) e006357, 1-12. doi: 10.1136/rmdopen-2025-006357 |
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2025 Journal Article Exploring lumbar spine posture and movement in sitting: a comparison between laboratory and real-world measuresAlshehri, Mansour Abdullah, Riddick, Ryan, Besomi, Manuela, van den Hoorn, Wolbert, Klyne, David M. and Hodges, Paul W. (2025). Exploring lumbar spine posture and movement in sitting: a comparison between laboratory and real-world measures. Journal of Clinical Medicine, 14 (21) 7518, 1-17. doi: 10.3390/jcm14217518 |
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2025 Journal Article Overuse injury induces persistent behavioral declines that correlate with higher IL-6 expression in the affected musculoskeletal tissues, circulation, and brainBarbe, Mary F., Lambi, Alex G., Harris, Michele Y., Patel, Parth R., Tamas, Istvan P., McGonagle, Elizabeth R., Van Der Bas, Megan, Kalicharan, Betsy A., Bright-Rowe, Lewis, Popoff, Steven N. and Klyne, David M. (2025). Overuse injury induces persistent behavioral declines that correlate with higher IL-6 expression in the affected musculoskeletal tissues, circulation, and brain. Frontiers in Physiology, 16 1500795, 1-25. doi: 10.3389/fphys.2025.1500795 |
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2025 Journal Article Addition of aerobic physical activity to resistance exercise for hip osteoarthritis (PHOENIX): a randomised comparative effectiveness trialHall, Michelle, Allison, Kim, Knox, Gabrielle, McManus, Fiona, Hinman, Rana S., Bennell, Kim L., Spiers, Libby, De Silva, Anurika P., Klyne, David M., Plinsinga, Melanie L., Costa, Ricardo J. S., Murphy, Nicholas J., Wu, Wen and Dobson, Fiona L. (2025). Addition of aerobic physical activity to resistance exercise for hip osteoarthritis (PHOENIX): a randomised comparative effectiveness trial. The Lancet Rheumatology, 7 (5), e343-e354. doi: 10.1016/s2665-9913(24)00373-4 |
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2025 Journal Article The role and treatment potential of the complement pathway in chronic painVygonskaya, Marina, Wu, Youzhi, Price, Theodore J., Chen, Zhuo, Smith, Maree T., Klyne, David M. and Han, Felicity Y. (2025). The role and treatment potential of the complement pathway in chronic pain. The Journal of Pain, 27 104689, 1-15. doi: 10.1016/j.jpain.2024.104689 |
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2024 Journal Article Should cognitive behavioral therapy for insomnia be considered for preventing and managing chronic pain? Klyne, David M., Smith, Simon S. and Hall, Michelle (2024). Should cognitive behavioral therapy for insomnia be considered for preventing and managing chronic pain? . Sleep, 47 (10) zsae177. doi: 10.1093/sleep/zsae177 |
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2024 Journal Article Poor lumbar spine coordination in acute low back pain predicts persistent long-term pain and disabilityAlshehri, Mansour Abdullah, van den Hoorn, Wolbert, Klyne, David M., van Dieën, Jaap H., Cholewicki, Jacek and Hodges, Paul W. (2024). Poor lumbar spine coordination in acute low back pain predicts persistent long-term pain and disability. European Spine Journal, 33 (6), 2380-2394. doi: 10.1007/s00586-024-08205-w |
