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2026 Journal Article Systemic C-reactive protein and vitamin D are not associated with development of chronic musculoskeletal pain over a 2–7 year follow-up periodCollyer, Martin R., Sterling, Michele, Armfield, Nigel R., Xie, Yanfei, Cabot, Peter J., Elphinston, Rachel A., Klyne, David M. and Farrell, Scott F. (2026). Systemic C-reactive protein and vitamin D are not associated with development of chronic musculoskeletal pain over a 2–7 year follow-up period. The Journal of Pain, 44 106297, 1-12. doi: 10.1016/j.jpain.2026.106297 |
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2026 Journal Article Neuroimmune pathways linking sleep disturbance to persistent pain after injury are mitigated by exerciseKlyne, David M., Van Der Bas, Megan, Harris, Michele Y., Hilliard, Brendan A., Patel, Parth R., Kegg, Abby, Rajpal, Astha, Ceasar, Khyleisha, Kalicharan, Betsy A., Hodges, Paul W. and Barbe, Mary F. (2026). Neuroimmune pathways linking sleep disturbance to persistent pain after injury are mitigated by exercise. Pain. doi: 10.1097/j.pain.0000000000003978 |
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2026 Journal Article Understanding the relationship between sleep, psychological and musculoskeletal health from a neuroimmune perspectiveKlyne, David M., Hall, Michelle, Smith, Simon S., Barbe, Mary F., Egorova-Brumley, Natalia, Serafimovska, Anastasia, Hodges, Paul W. and Suraev, Anastasia (2026). Understanding the relationship between sleep, psychological and musculoskeletal health from a neuroimmune perspective. Musculoskeletal Science and Practice, 82 103509, 1-12. doi: 10.1016/j.msksp.2026.103509 |
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2026 Journal Article Pain and the immune systemHodges, Paul W., Fiore, Nathan T., Watkins, Linda R., Klyne, David M., Coppieters, Michel W. and Grace, Peter M. (2026). Pain and the immune system. Musculoskeletal Science and Practice, 82 103484, 1-14. doi: 10.1016/j.msksp.2025.103484 |
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2026 Journal Article Time to wake up to the potential benefits of targeting sleep in osteoarthritis managementHall, Michelle, Ferreira, Paulo, Eyles, Jillian, Hawker, Gillian, Smith, Simon S., Egorova-Brumley, Natalia, McCurry, Susan M., Thorlund, Jonas B. and Klyne, David M (2026). Time to wake up to the potential benefits of targeting sleep in osteoarthritis management. Osteoarthritis and Cartilage. doi: 10.1016/j.joca.2026.03.122 |
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2026 Journal Article A Phase III triple-blind randomised placebo-controlled trial to evaluate effectiveness of early treatment with pregabalin to reduce pain severity after whiplash road traffic injury: study protocol for the PRioRTI Trial {1}Sterling, Michele, Farrell, Scott F., Ferguson, Lisa, Mitchell, Geoffrey, Schug, Stephan, Ware, Robert S., Dinh, Michael, Celenza, Antonio, Connelly, Luke, Hodges, Paul W., Klyne, David M., Elphinston, Rachel, Nikles, Jane, McAuley, James and Lin, Chung-Wei Christine (2026). A Phase III triple-blind randomised placebo-controlled trial to evaluate effectiveness of early treatment with pregabalin to reduce pain severity after whiplash road traffic injury: study protocol for the PRioRTI Trial {1}. Trials, 27 (1) 186, 1-13. doi: 10.1186/s13063-026-09479-9 |
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2026 Journal Article Neuroimmune interactions in musculoskeletal conditions. An introduction for cliniciansLutke Schipholt, Ivo J., Coppieters, Michel W., Scholten-Peeters, Gwendolyne G.M., Hutchinson, Mark R. and Klyne, David M. (2026). Neuroimmune interactions in musculoskeletal conditions. An introduction for clinicians. Musculoskeletal Science and Practice, 81 103469. doi: 10.1016/j.msksp.2025.103469 |
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2026 Journal Article Insomnia and progression to total joint replacement in hip (41 737) and knee pain (81 958): a prospective UK biobank cohort studyHaber, Travis, Dyer, Brett, Klyne, David M., Ferreira, Paulo H., Nicolson, Philippa J A, Lawford, Belinda J., McCurry, Susan M. and Hall, Michelle (2026). Insomnia and progression to total joint replacement in hip (41 737) and knee pain (81 958): a prospective UK biobank cohort study. RMD Open, 12 (1) e006357, 1-12. doi: 10.1136/rmdopen-2025-006357 |
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2025 Journal Article Exploring lumbar spine posture and movement in sitting: a comparison between laboratory and real-world measuresAlshehri, Mansour Abdullah, Riddick, Ryan, Besomi, Manuela, van den Hoorn, Wolbert, Klyne, David M. and Hodges, Paul W. (2025). Exploring lumbar spine posture and movement in sitting: a comparison between laboratory and real-world measures. Journal of Clinical Medicine, 14 (21) 7518, 1-17. doi: 10.3390/jcm14217518 |
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2025 Conference Publication O036 Sleep moderates but does not mediate aerobic benefits in osteoarthritisWang, M, Dobson, F, Klyne, D, Ferreira, P, Allison, K, Knox, G, Hinman, R, Bennell, K, Spiers, L and Hall, M (2025). O036 Sleep moderates but does not mediate aerobic benefits in osteoarthritis. Oxford University Press (OUP). doi: 10.1093/sleepadvances/zpaf053.036 |
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2025 Conference Publication O021 Associations between signs of insomnia and incident joint replacementHaber, T, Dyer, B, Klyne, D, Ferreira, P, Nicolson, P, Lawford, B, McCurry, S and Hall, M (2025). O021 Associations between signs of insomnia and incident joint replacement. Oxford University Press (OUP). doi: 10.1093/sleepadvances/zpaf053.021 |
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2025 Conference Publication O035 Sleep status informs exercise prescription in hip osteoarthritisKlyne, D, Chan, S, Dobson, F, Allison, K, Knox, G, Spiers, L and Hall, M (2025). O035 Sleep status informs exercise prescription in hip osteoarthritis. Oxford University Press (OUP). doi: 10.1093/sleepadvances/zpaf053.035 |
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2025 Conference Publication O037 Improved sleep is associated with improved hip osteoarthritis symptomsZhang, H, Dobson, F, Allison, K, Klyne, D, Ferreira, P, Venkatesha, V and Hall, M (2025). O037 Improved sleep is associated with improved hip osteoarthritis symptoms. Oxford University Press (OUP). doi: 10.1093/sleepadvances/zpaf053.037 |
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2025 Journal Article Overuse injury induces persistent behavioral declines that correlate with higher IL-6 expression in the affected musculoskeletal tissues, circulation, and brainBarbe, Mary F., Lambi, Alex G., Harris, Michele Y., Patel, Parth R., Tamas, Istvan P., McGonagle, Elizabeth R., Van Der Bas, Megan, Kalicharan, Betsy A., Bright-Rowe, Lewis, Popoff, Steven N. and Klyne, David M. (2025). Overuse injury induces persistent behavioral declines that correlate with higher IL-6 expression in the affected musculoskeletal tissues, circulation, and brain. Frontiers in Physiology, 16 1500795, 1-25. doi: 10.3389/fphys.2025.1500795 |
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2025 Journal Article Addition of aerobic physical activity to resistance exercise for hip osteoarthritis (PHOENIX): a randomised comparative effectiveness trialHall, Michelle, Allison, Kim, Knox, Gabrielle, McManus, Fiona, Hinman, Rana S., Bennell, Kim L., Spiers, Libby, De Silva, Anurika P., Klyne, David M., Plinsinga, Melanie L., Costa, Ricardo J. S., Murphy, Nicholas J., Wu, Wen and Dobson, Fiona L. (2025). Addition of aerobic physical activity to resistance exercise for hip osteoarthritis (PHOENIX): a randomised comparative effectiveness trial. The Lancet Rheumatology, 7 (5), e343-e354. doi: 10.1016/s2665-9913(24)00373-4 |
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2025 Journal Article The role and treatment potential of the complement pathway in chronic painVygonskaya, Marina, Wu, Youzhi, Price, Theodore J., Chen, Zhuo, Smith, Maree T., Klyne, David M. and Han, Felicity Y. (2025). The role and treatment potential of the complement pathway in chronic pain. The Journal of Pain, 27 104689, 1-15. doi: 10.1016/j.jpain.2024.104689 |
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2024 Journal Article Should cognitive behavioral therapy for insomnia be considered for preventing and managing chronic pain? Klyne, David M., Smith, Simon S. and Hall, Michelle (2024). Should cognitive behavioral therapy for insomnia be considered for preventing and managing chronic pain? . Sleep, 47 (10) zsae177. doi: 10.1093/sleep/zsae177 |
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2024 Book Chapter Biological Contributors to Musculoskeletal Pain and DisabilityFarrell, Scott F., deZoete, Rutger M.J., Klyne, David M., Schmid, Annina B., Polli, Andrea, Nijs, Jo and Sterling, Michele (2024). Biological Contributors to Musculoskeletal Pain and Disability. Grieve's Modern Musculoskeletal Physiotherapy. (pp. 22-35) edited by Deborah Falla, Jeremy Lewis, Christopher McCarthy, Chad E. Cook and Michele Sterling. London, United Kingdom: Elsevier. doi: 10.1016/B978-0-7020-8089-0.00005-7 |
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2024 Conference Publication The Additive Effects Of Aerobic Activity To Strengthening Exercise For Hip Osteoarthritis: A Randomized Controlled TrialHall, Michelle, Allison, Kim, Knox, Gabrielle, Hinman, Rana S., Bennell, Kim, Spiers, Libby, Plinsinga, Melanie, Klyne, David, McManus, Fiona, De Silva, Anurika, Da Costa, Ricardo, Murphy, Nicholas and Dobson, Fiona (2024). The Additive Effects Of Aerobic Activity To Strengthening Exercise For Hip Osteoarthritis: A Randomized Controlled Trial. 2024 OARSI World Congress on Osteoarthritis, Vienna, Austria, 18-21 April 2024. London, United Kingdom: Elsevier. doi: 10.1016/j.joca.2024.03.098 |
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2024 Journal Article Poor lumbar spine coordination in acute low back pain predicts persistent long-term pain and disabilityAlshehri, Mansour Abdullah, van den Hoorn, Wolbert, Klyne, David M., van Dieën, Jaap H., Cholewicki, Jacek and Hodges, Paul W. (2024). Poor lumbar spine coordination in acute low back pain predicts persistent long-term pain and disability. European Spine Journal, 33 (6), 2380-2394. doi: 10.1007/s00586-024-08205-w |
