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2025

Journal Article

TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation

Schultz, Thomas E., Mathmann, Carmen D., Domínguez Cadena, Leslie C., Muusse, Timothy W., Kim, Hyoyoung, Wells, James W., Ulett, Glen C., Hamerman, Jessica A., Brooks, Andrew J., Kobe, Bostjan, Sweet, Matthew J., Stacey, Katryn J. and Blumenthal, Antje (2025). TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation. EMBO Reports, 26 (10) 2250056, 2740-2766. doi: 10.1038/s44319-025-00444-2

TLR4 endocytosis and endosomal TLR4 signaling are distinct and independent outcomes of TLR4 activation

2025

Journal Article

Neural network assisted annotation and analysis tool to study in-vivo foveolar cone photoreceptor topography

Gutnikov, Aleksandr, Haehn-Schumacher, Patrick, Ameln, Julius, Zadeh, Shekoufeh Gorgi, Schultz, Thomas and Harmening, Wolf (2025). Neural network assisted annotation and analysis tool to study in-vivo foveolar cone photoreceptor topography. Scientific Reports, 15 (1) 23858, 1-13. doi: 10.1038/s41598-025-08028-9

Neural network assisted annotation and analysis tool to study in-vivo foveolar cone photoreceptor topography

2025

Journal Article

GestaltGAN: synthetic photorealistic portraits of individuals with rare genetic disorders

Kirchhoff, Aron, Hustinx, Alexander, Javanmardi, Behnam, Hsieh, Tzung-Chien, Brand, Fabian, Hellmann, Fabio, Mertes, Silvan, Andre, Elisabeth, Moosa, Shahida, Schultz, Thomas, Solomon, Benjamin D. and Krawitz, Peter (2025). GestaltGAN: synthetic photorealistic portraits of individuals with rare genetic disorders. European Journal of Human Genetics, 33 (3), 377-382. doi: 10.1038/s41431-025-01787-z

GestaltGAN: synthetic photorealistic portraits of individuals with rare genetic disorders

2024

Journal Article

Myddosomes in Toll-like receptor signaling-one to bind and rule them all

Mathmann, Carmen D., Schultz, Thomas E., Cadena, Leslie C. Dominguez and Blumenthal, Antje (2024). Myddosomes in Toll-like receptor signaling-one to bind and rule them all. Immunology and Cell Biology, 102 (9), 752-756. doi: 10.1111/imcb.12816

Myddosomes in Toll-like receptor signaling-one to bind and rule them all

2022

Journal Article

Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculosis

Donovan, Meg L., Bielefeldt‐Ohmann, Helle, Rollo, Rachel F., McPherson, Stephen, Schultz, Thomas E., Mori, Giorgia, Kling, Jessica C. and Blumenthal, Antje (2022). Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculosis. Immunology, 169 (1), 13-26. doi: 10.1111/imm.13606

Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculosis

2021

Journal Article

Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection

Domínguez Cadena, Leslie C., Schultz, Thomas E., Zamoshnikova, Alina, Donovan, Meg L., Mathmann, Carmen D., Yu, Chien-Hsiung, Mori, Giorgia, Stow, Jennifer L and Blumenthal, Antje (2021). Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection. Immunology and Cell Biology, 99 (10), 1067-1076. doi: 10.1111/imcb.12503

Rab6b localizes to the Golgi complex in murine macrophages and promotes tumor necrosis factor release in response to mycobacterial infection

2020

Journal Article

Vulnerabilities and Reliability of ReRAM Based PUFs and Memory Logic

Schultz, Thomas, Jha, Rashmi, Casto, Matt and Dupaix, Brian (2020). Vulnerabilities and Reliability of ReRAM Based PUFs and Memory Logic. Ieee Transactions On Reliability, 69 (2), 690-698. doi: 10.1109/TR.2019.2910793

Vulnerabilities and Reliability of ReRAM Based PUFs and Memory Logic

2019

Journal Article

Replicated landscape genomics identifies evidence of local adaptation to urbanization in wood frogs

Homola, Jared J., Loftin, Cynthia S., Cammen, Kristina M., Helbing, Caren C., Birol, Inanc, Schultz, Thomas F. and Kinnison, Michael T. (2019). Replicated landscape genomics identifies evidence of local adaptation to urbanization in wood frogs. Journal of Heredity, 110 (6), 707-719. doi: 10.1093/jhered/esz041

Replicated landscape genomics identifies evidence of local adaptation to urbanization in wood frogs

2018

Journal Article

Genomic signatures of population bottleneck and recovery in Northwest Atlantic pinnipeds

Cammen, Kristina M., Schultz, Thomas F., Bowen, W. Don, Hammill, Michael O., Puryear, Wendy B., Runstadler, Jonathan, Wenzel, Frederick W., Wood, Stephanie A. and Kinnison, Michael (2018). Genomic signatures of population bottleneck and recovery in Northwest Atlantic pinnipeds. Ecology and Evolution, 8 (13), 6599-6614. doi: 10.1002/ece3.4143

Genomic signatures of population bottleneck and recovery in Northwest Atlantic pinnipeds

2018

Journal Article

The N-terminal peptide moiety of the Mycobacterium tuberculosis 19 kDa lipoprotein harbors RP105-agonistic properties

Schultz, Thomas E., Wiesmüller, Karl-Heinz, Lucas, Megan, Dobos, Karen M., Baxter, Alan G. and Blumenthal, Antje (2018). The N-terminal peptide moiety of the Mycobacterium tuberculosis 19 kDa lipoprotein harbors RP105-agonistic properties. Journal of Leukocyte Biology, 103 (2), 311-319. doi: 10.1002/JLB.2MA0517-190RR

The N-terminal peptide moiety of the Mycobacterium tuberculosis 19 kDa lipoprotein harbors RP105-agonistic properties

2017

Journal Article

Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences

Donovan, Meg L., Schultz, Thomas E., Duke, Taylor J. and Blumenthal, Antje (2017). Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences. Frontiers in Immunology, 8 (NOV) 1633, 1-16. doi: 10.3389/fimmu.2017.01633

Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences

2017

Journal Article

Cost of Tolerance: Physiological Consequences of Evolved Resistance to Inhabit a Polluted Environment in Teleost Fish <i>Fundulus heteroclitus</i>

Jayasundara, Nishad, Fernando, Pani W., Osterberg, Joshua S., Cammen, Kristina M., Schultz, Thomas F. and Di Giulio, Richard T. (2017). Cost of Tolerance: Physiological Consequences of Evolved Resistance to Inhabit a Polluted Environment in Teleost Fish Fundulus heteroclitus. Environmental Science & Technology, 51 (15), 8763-8772. doi: 10.1021/acs.est.7b01913

Cost of Tolerance: Physiological Consequences of Evolved Resistance to Inhabit a Polluted Environment in Teleost Fish <i>Fundulus heteroclitus</i>

2017

Journal Article

The RP105/MD-1 complex: molecular signaling mechanisms and pathophysiological implications

Schultz, Thomas E. and Blumenthal, Antje (2017). The RP105/MD-1 complex: molecular signaling mechanisms and pathophysiological implications. Journal of Leukocyte Biology, 101 (1), 183-192. doi: 10.1189/jlb.2VMR1215-582R

The RP105/MD-1 complex: molecular signaling mechanisms and pathophysiological implications

2015

Journal Article

RP105 engages phosphatidylinositol 3-kinase p110δ to facilitate the trafficking and secretion of cytokines in macrophages during mycobacterial infection

Yu, Chien-Hsiung, Micaroni, Massimo, Puyskens, Andreas, Schultz, Thomas E., Yeo, Jeremy Changyu, Stanley, Amanda C., Lucas, Megan, Kurihara, Jade, Dobos, Karen M., Stow, Jennifer L. and Blumenthal, Antje (2015). RP105 engages phosphatidylinositol 3-kinase p110δ to facilitate the trafficking and secretion of cytokines in macrophages during mycobacterial infection. Journal of Immunology, 195 (8), 3890-3900. doi: 10.4049/jimmunol.1500017

RP105 engages phosphatidylinositol 3-kinase p110δ to facilitate the trafficking and secretion of cytokines in macrophages during mycobacterial infection