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2025

Conference Publication

Live-cell single-molecule imaging of a new fluorescent C5a receptor antagonist reveals the heterogeneous spatiotemporal dynamics of C5aR1 at the plasma membrane

Sun, Jinda, Parker, Sandra, Lee, Jonathan, Gorman, Declan, Li, Xaria, Albornoz Balmaceda, Eduardo, Bellingham, Mark, Clark, Richard, Woodruff, Trent and Padmanabhan, Pranesh (2025). Live-cell single-molecule imaging of a new fluorescent C5a receptor antagonist reveals the heterogeneous spatiotemporal dynamics of C5aR1 at the plasma membrane. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.152969

Live-cell single-molecule imaging of a new fluorescent C5a receptor antagonist reveals the heterogeneous spatiotemporal dynamics of C5aR1 at the plasma membrane

2025

Conference Publication

Microglial Complement C5aR1 signalling drives inflammasome mediated neuropathology in Parkinson’s disease

Albornoz, Eduardo, Gordon, Richard, Javed, Ibrahim, Bodea, Gabriela, Kumar, Vinod, Cui, Cedric, Aguado, Julio, Mardon, Karine, Bhalla, Rajiv, Cowin, Gary and Woodruff, Trent (2025). Microglial Complement C5aR1 signalling drives inflammasome mediated neuropathology in Parkinson’s disease. 30th International Complement Workshop 2025, Brisbane, QLD Australia, 14-19 September 2025. Muenchen, Germany: Elsevier. doi: 10.1016/j.imbio.2025.152955

Microglial Complement C5aR1 signalling drives inflammasome mediated neuropathology in Parkinson’s disease

2025

Conference Publication

Motor neuron disease C9orf72 dipeptides mediate neurotoxicity in human brain organoids through activation of C5aR1

Cao, Yuzhihan, Pietrogrande, Giovanni, Pars, Selin, Clark, Richard, Wolvetang, Ernst, Woodruff, Trent and Albornoz, Eduardo (2025). Motor neuron disease C9orf72 dipeptides mediate neurotoxicity in human brain organoids through activation of C5aR1. 30th International Complement Workshop 2025, Brisbane, QLD, Australia, 14-19 September 2025. Munich, Germany: Elsevier. doi: 10.1016/j.imbio.2025.153008

Motor neuron disease C9orf72 dipeptides mediate neurotoxicity in human brain organoids through activation of C5aR1

2018

Conference Publication

C5aR1 is required for a-synuclein mediated NLRP3 inflammasome activation

Gordon, Richard, Albornoz, Eduardo, Kanthasamy, Anumantha and Woodruff, Trent (2018). C5aR1 is required for a-synuclein mediated NLRP3 inflammasome activation. 27th International Complement Workshop (ICW), Santa Fe, NM, United States, Sep 16-20, 2018. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2018.06.247

C5aR1 is required for a-synuclein mediated NLRP3 inflammasome activation

2017

Conference Publication

Gestational hypothyroxinemia increases the immune response of the progeny that suffers experimental autoimmune encephalomyelitis

Opazo, Maria Cecilia, Bugueño, Katherinne, Jara, Evelyn, Haensgen, Henny, Albornoz, Eduardo, Gomez, Felipe, Binzberger, Rebecca, Toledo, Paola, Blanco, Noelia, Simon, Felipe, Elorza, Alvaro, Kalergis, Alexis, Bueno, Susan and Riedel, Claudia (2017). Gestational hypothyroxinemia increases the immune response of the progeny that suffers experimental autoimmune encephalomyelitis. Immunology 2017™ Meeting, Washington, DC United States, 12-16 May 2017. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.198.supp.207.8

Gestational hypothyroxinemia increases the immune response of the progeny that suffers experimental autoimmune encephalomyelitis

2017

Conference Publication

Gut microbiome changes induced by experimental trichuris muris infection are associated with decreased cognitive function in mice

Magalhaes, Ricardo J. Soares, Giacomin, Paul, Sarnyay, Zoltan, Kraeuter, Ann, Urich, Tim, Bengtsson, Mia, Jin, Shuting, Albornoz, Eduardo A., Gordon, Richard and Woodruff, Trent (2017). Gut microbiome changes induced by experimental trichuris muris infection are associated with decreased cognitive function in mice. 65th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene (ASTMH), Atlanta, GA, United States, 13-16 November 2016. Deerfield, United States: American Society of Tropical Medicine and Hygiene.

Gut microbiome changes induced by experimental trichuris muris infection are associated with decreased cognitive function in mice

2016

Conference Publication

Complement C5a activates microglial NLRP3 inflammasomes and drives neurodegeneration in Parkinson's disease through C5aR1

Gordon, Richard, Albornoz, Eduardo A., Kumar, Vinod, Zhou, Kiane, Garin-Michaud, Ashoka, Mantavani, Susanna, Kanthasamy, Anumantha G. and Woodruff, Trent M. (2016). Complement C5a activates microglial NLRP3 inflammasomes and drives neurodegeneration in Parkinson's disease through C5aR1. The XXVI International Complement Workshop (ICW), Kanazawa, Japan, 4-8 September 2016. Muenchen, Germany: Elsevier. doi: 10.1016/j.imbio.2016.06.146

Complement C5a activates microglial NLRP3 inflammasomes and drives neurodegeneration in Parkinson's disease through C5aR1

2015

Conference Publication

Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathway

Albornoz, E., Deora, V., Robertson, B. A., Cooper, M. A., Schroder, K., Woodruff, T. M. and Gordon, R. (2015). Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathway. International Congress of Immunology (ICI), Melbourne, Australia, Aug 21-26, 2016. Weinheim, Germany: Wiley-Blackwell.

Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathway