|
2020 Conference Publication Using genetics to understand the relationship between non-cancerous gynaecological diseases and endometrial cancer riskO'Mara, T. A., Kho, P., Mortlock, S., Montgomery, G. W., Spurdle, A. B. and Glubb, D. M. (2020). Using genetics to understand the relationship between non-cancerous gynaecological diseases and endometrial cancer risk. LONDON: SPRINGERNATURE. |
|
2020 Journal Article Variant effect on splicing regulatory elements, branchpoint usage, and pseudoexonization: strategies to enhance bioinformatic prediction using hereditary cancer genes as exemplarsCanson, Daffodil, Glubb, Dylan and Spurdle, Amanda B. (2020). Variant effect on splicing regulatory elements, branchpoint usage, and pseudoexonization: strategies to enhance bioinformatic prediction using hereditary cancer genes as exemplars. Human Mutation, 41 (10) humu.24074, 1705-1721. doi: 10.1002/humu.24074 |
|
2020 Journal Article Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndromeDrost, Mark, Tiersma, Yvonne, Glubb, Dylan, Kathe, Scott, van Hees, Sandrine, Calléja, Fabienne, Zonneveld, José B. M., Boucher, Kenneth M., Ramlal, Renuka P. E., Thompson, Bryony A., Rasmussen, Lene Juel, Greenblatt, Marc S., Lee, Andrea, Spurdle, Amanda B., Tavtigian, Sean V. and de Wind, Niels (2020). Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome. Genetics in Medicine, 22 (5), 847-856. doi: 10.1038/s41436-019-0736-2 |
|
2020 Journal Article Candidate causal variants at the 8p12 breast cancer risk locus regulate DUSP4Glubb, Dylan M., Shi, Wei, Beesley, Jonathan, Fachal, Laura, Pritchard, Jayne-Louise, McCue, Karen, Barnes, Daniel R., Antoniou, Antonis C., Dunning, Alison M., Easton, Douglas F. and Chenevix-Trench, Georgia (2020). Candidate causal variants at the 8p12 breast cancer risk locus regulate DUSP4. Cancers, 12 (1) 170, 170. doi: 10.3390/cancers12010170 |
|
2019 Journal Article Analysis of promoter-associated chromatin interactions reveals biologically relevant candidate target genes at endometrial cancer risk lociO’Mara, Tracy A., Spurdle, Amanda B. and Glubb, Dylan M. (2019). Analysis of promoter-associated chromatin interactions reveals biologically relevant candidate target genes at endometrial cancer risk loci. Cancers, 11 (10) 1440, 1440. doi: 10.3390/cancers11101440 |
|
2019 Journal Article Genome-wide association studies of endometrial cancer: latest developments and future directionsO'Mara, Tracy A., Glubb, Dylan M., Kho, Pik Fang, Thompson, Deborah J. and Spurdle, Amanda B. (2019). Genome-wide association studies of endometrial cancer: latest developments and future directions. Cancer Epidemiology Biomarkers and Prevention, 28 (7), 1095-1102. doi: 10.1158/1055-9965.epi-18-1031 |
|
2019 Journal Article A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndromeDrost, Mark, Tiersma, Yvonne, Thompson, Bryony A., Frederiksen, Jane H., Keijzers, Guido, Glubb, Dylan, Kathe, Scott, Osinga, Jan, Westers, Helga, Pappas, Lisa, Boucher, Kenneth M., Molenkamp, Siska, Zonneveld, José B., van Asperen, Christi J., Goldgar, David E., Wallace, Susan S., Sijmons, Rolf H., Spurdle, Amanda B., Rasmussen, Lene J., Greenblatt, Marc S., de Wind, Niels and Tavtigian, Sean V. (2019). A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome. Genetics in Medicine, 21 (7), 1486-1496. doi: 10.1038/s41436-018-0372-2 |
|
2019 Journal Article Assessing the role of selenium in endometrial cancer risk: a Mendelian randomization studyKho, Pik Fang, Glubb, Dylan M., Thompson, Deborah J., Spurdle, Amanda B. and O'Mara, Tracy A. (2019). Assessing the role of selenium in endometrial cancer risk: a Mendelian randomization study. Frontiers in Oncology, 9 (MAR) 182. doi: 10.3389/fonc.2019.00182 |
|
2019 Journal Article Editorial: establishing genetic pleiotropy to identify common pharmacological agents for common diseasesO'Mara, Tracy A., Batra, Jyotsna and Glubb, Dylan (2019). Editorial: establishing genetic pleiotropy to identify common pharmacological agents for common diseases. Frontiers in Pharmacology, 10 1038. doi: 10.3389/fphar.2019.01038 |
|
2019 Journal Article Genetic variants of VEGFA and FLT4 are determinants of survival in renal cell carcinoma patients treated with sorafenibCrona, Daniel J., Skol, Andrew D., Leppänen, Veli-Matti, Glubb, Dylan M., Etheridge, Amy S., Hilliard, Eleanor, Peña, Carol E., Peterson, Yuri K., Klauber-DeMore, Nancy, Alitalo, Kari K. and Innocenti, Federico (2019). Genetic variants of VEGFA and FLT4 are determinants of survival in renal cell carcinoma patients treated with sorafenib. Cancer Research, 79 (1), 231-241. doi: 10.1158/0008-5472.can-18-1089 |
|
2018 Journal Article Identification of nine new susceptibility loci for endometrial cancerO’Mara, Tracy A., Glubb, Dylan M., Amant, Frederic, Annibali, Daniela, Ashton, Katie, Attia, John, Auer, Paul L., Beckmann, Matthias W., Black, Amanda, Bolla, Manjeet K., Brauch, Hiltrud, Brenner, Hermann, Brinton, Louise, Buchanan, Daniel D., Burwinkel, Barbara, Chang-Claude, Jenny, Chanock, Stephen J., Chen, Chu, Chen, Maxine M., Cheng, Timothy H. T., Clarke, Christine L., Clendenning, Mark, Cook, Linda S., Couch, Fergus J., Cox, Angela, Crous-Bous, Marta, Czene, Kamila, Day, Felix, Dennis, Joe ... Thompson, Deborah J. (2018). Identification of nine new susceptibility loci for endometrial cancer. Nature Communications, 9 (1) 3166, 3166. doi: 10.1038/s41467-018-05427-7 |
|
2018 Journal Article The Vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validationInnocenti, Federico, Owzar, Kouros, Jiang, Chen, Etheridge, Amy S., Gordân, Raluca, Sibley, Alexander B., Mulkey, Flora, Niedzwiecki, Donna, Glubb, Dylan, Neel, Nicole, Talamonti, Mark S., Bentrem, David J., Seiser, Eric, Yeh, Jen Jen, Van Loon, Katherine, McLeod, Howard, Ratain, Mark J., Kindler, Hedy L., Venook, Alan P., Nakamura, Yusuke, Kubo, Michiaki, Petersen, Gloria M., Bamlet, William R. and McWilliams, Robert R. (2018). The Vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation. PLoS One, 13 (8) e0202272, 1-14. doi: 10.1371/journal.pone.0202272 |
|
2018 Journal Article Erratum: Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (Nature communications (2014) 4 (4999))Ghoussaini, Maya, Edwards, Stacey L., Michailidou, Kyriaki, Nord, Silje, Cowper-Sal Lari, Richard, Desai, Kinjal, Kar, Siddhartha, Hillman, Kristine M., Kaufmann, Susanne, Glubb, Dylan M., Beesley, Jonathan, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Guo, Qi, Schmidt, Marjanka K., Shah, Mitul, Luben, Robert, Brown, Judith, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Bojesen, Stig E., Nordestgaard, Børge G, Nielsen, Sune F., Flyger, Henrik, Lambrechts, Diether ... Dunning, Alison M. (2018). Erratum: Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (Nature communications (2014) 4 (4999)). Nature communications, 9 (1) 16193. doi: 10.1038/ncomms16193 |
|
2017 Journal Article Enhancing the Promise of Drug Repositioning through GeneticsPritchard, Jayne-Louise E., O’Mara, Tracy A. and Glubb, Dylan M. (2017). Enhancing the Promise of Drug Repositioning through Genetics. Frontiers in Pharmacology, 8 (DEC) 896. doi: 10.3389/fphar.2017.00896 |
|
2017 Journal Article Association analysis identifies 65 new breast cancer risk lociMichailidou, Kyriaki, Lindström, Sara, Dennis, Joe, Beesley, Jonathan, Hui, Shirley, Kar, Siddhartha, Lemaçon, Audrey, Soucy, Penny, Glubb, Dylan, Rostamianfar, Asha, Bolla, Manjeet K, Wang, Qin, Tyrer, Jonathan, Dicks, Ed, Lee, Andrew, Wang, Zhaoming, Allen, Jamie, Keeman, Renske, Eilber, Ursula, French, Juliet D, Qing Chen, Xiao, Fachal, Laura, McCue, Karen, McCart Reed, Amy E, Ghoussaini, Maya, Carroll, Jason S, Jiang, Xia, Finucane, Hilary, Adams, Marcia ... Easton, Douglas F (2017). Association analysis identifies 65 new breast cancer risk loci. Nature, 551 (7678), 92-94. doi: 10.1038/nature24284 |
|
2017 Journal Article The association of CYP19A1 variation with circulating estradiol and aromatase inhibitor outcome: Can CYP19A1 variants be used to predict treatment efficacy?Glubb, Dylan M., O'Mara, Tracy A., Shamsani, Jannah and Spurdle, Amanda B. (2017). The association of CYP19A1 variation with circulating estradiol and aromatase inhibitor outcome: Can CYP19A1 variants be used to predict treatment efficacy?. Frontiers in Pharmacology, 8 (April) 218, 1-8. doi: 10.3389/fphar.2017.00218 |
|
2017 Journal Article Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome lociGlubb, Dylan M., Johnatty, Sharon E., Quinn, Michael C. J., O'Mara, Tracy A., Tyrer, Jonathan P., Gao, Bo, Fasching, Peter A., Beckmann, Matthias W., Lambrechts, Diether, Vergote, Ignace, Edwards, Digna R. Velez, Beeghly-Fadiel, Alicia, Benitez, Javier, Garcia, Maria J., Goodman, Marc T., Thompson, Pamela J., Dörk, Thilo, Dürst, Matthias, Modungo, Francesmary, Moysich, Kirsten, Heitz, Florian, du Bois, Andreas, Pfisterer, Jacobus, Hillemanns, Peter, Karlan, Beth Y., Lester, Jenny, Goode, Ellen L., Cunningham, Julie M., Winham, Stacey J. ... Chenevix-Trench, Georgia (2017). Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci. OncoTarget, 8 (39), 64670-64684. doi: 10.18632/oncotarget.18501 |
|
2016 Journal Article Five endometrial cancer risk loci identified through genome-wide association analysisCheng, Timothy H. T., Thompson, Deborah J., O'Mara, Tracy A., Painter, Jodie N., Glubb, Dylan M., Flach, Susanne, Lewis, Annabelle, French, Juliet D., Freeman-Mills, Luke, Church, David, Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Webb, Penelope M., Attia, John, Holliday, Elizabeth G., McEvoy, Mark, Scott, Rodney J., Henders, Anjali K., Martin, Nicholas G., Montgomery, Grant W., Nyholt, Dale R., Ahmed, Shahana, Healey, Catherine S., Shah, Mitul, Dennis, Joe, Fasching, Peter A., Beckmann, Matthias W., Hein, Alexander ... Spurdle, Amanda B. (2016). Five endometrial cancer risk loci identified through genome-wide association analysis. Nature Genetics, 48 (6), 667-674. doi: 10.1038/ng.3562 |
|
2016 Journal Article CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancerThompson, Deborah J., O'Mara, Tracy A., Glubb, Dylan M., Painter, Jodie N., Cheng, Timothy, Folkerd, Elizabeth, Doody, Deborah, Dennis, Joe, Webb, Penelope M., Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Michailidou, Kyriaki, Tyrer, Jonathan P., Maranian, Mel J., Hall, Per, Czene, Kamila, Darabi, Hatef, Li, Jingmei, Fasching, Peter A., Hein, Alexander, Beckmann, Matthias W., Ekici, Arif B., Doerk, Thilo, Hillemanns, Peter, Duerst, Matthias, Runnebaum, Ingo, Zhao, Hui, Depreeuw, Jeroen ... Spurdle, Amanda B. (2016). CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer. Endocrine-Related Cancer, 23 (2), 77-91. doi: 10.1530/ERC-15-0386 |
|
2015 Journal Article Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancerO'Mara, Tracy A., Glubb, Dylan M., Painter, Jodie N., Cheng, Timothy, Dennis, Joe, Attia, John, Holliday, Elizabeth G., McEvoy, Mark, Scott, Rodney J., Ashton, Katie, Proietto, Tony, Otton, Geoffrey, Shah, Mitul, Ahmed, Shahana, Healey, Catherine S., Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Fasching, Peter A., Hein, Alexander, Beckmann, Matthias W., Ekici, Arif B., Hall, Per, Czene, Kamila, Darabi, Hatef, Li, Jingmei, Duerst, Matthias, Runnebaum, Ingo, Hillemanns, Peter ... Spurdle, Amanda B. (2015). Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer. Endocrine-Related Cancer, 22 (5), 851-861. doi: 10.1530/ERC-15-0319 |
