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2018 Journal Article Erratum: Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (Nature communications (2014) 4 (4999))Ghoussaini, Maya, Edwards, Stacey L., Michailidou, Kyriaki, Nord, Silje, Cowper-Sal Lari, Richard, Desai, Kinjal, Kar, Siddhartha, Hillman, Kristine M., Kaufmann, Susanne, Glubb, Dylan M., Beesley, Jonathan, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Guo, Qi, Schmidt, Marjanka K., Shah, Mitul, Luben, Robert, Brown, Judith, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Bojesen, Stig E., Nordestgaard, Børge G, Nielsen, Sune F., Flyger, Henrik, Lambrechts, Diether ... Dunning, Alison M. (2018). Erratum: Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (Nature communications (2014) 4 (4999)). Nature communications, 9 (1) 16193. doi: 10.1038/ncomms16193 |
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2017 Journal Article Enhancing the Promise of Drug Repositioning through GeneticsPritchard, Jayne-Louise E., O’Mara, Tracy A. and Glubb, Dylan M. (2017). Enhancing the Promise of Drug Repositioning through Genetics. Frontiers in Pharmacology, 8 (DEC) 896. doi: 10.3389/fphar.2017.00896 |
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2017 Journal Article Association analysis identifies 65 new breast cancer risk lociMichailidou, Kyriaki, Lindström, Sara, Dennis, Joe, Beesley, Jonathan, Hui, Shirley, Kar, Siddhartha, Lemaçon, Audrey, Soucy, Penny, Glubb, Dylan, Rostamianfar, Asha, Bolla, Manjeet K, Wang, Qin, Tyrer, Jonathan, Dicks, Ed, Lee, Andrew, Wang, Zhaoming, Allen, Jamie, Keeman, Renske, Eilber, Ursula, French, Juliet D, Qing Chen, Xiao, Fachal, Laura, McCue, Karen, McCart Reed, Amy E, Ghoussaini, Maya, Carroll, Jason S, Jiang, Xia, Finucane, Hilary, Adams, Marcia ... Easton, Douglas F (2017). Association analysis identifies 65 new breast cancer risk loci. Nature, 551 (7678), 92-94. doi: 10.1038/nature24284 |
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2017 Journal Article The association of CYP19A1 variation with circulating estradiol and aromatase inhibitor outcome: Can CYP19A1 variants be used to predict treatment efficacy?Glubb, Dylan M., O'Mara, Tracy A., Shamsani, Jannah and Spurdle, Amanda B. (2017). The association of CYP19A1 variation with circulating estradiol and aromatase inhibitor outcome: Can CYP19A1 variants be used to predict treatment efficacy?. Frontiers in Pharmacology, 8 (April) 218, 1-8. doi: 10.3389/fphar.2017.00218 |
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2017 Journal Article Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome lociGlubb, Dylan M., Johnatty, Sharon E., Quinn, Michael C. J., O'Mara, Tracy A., Tyrer, Jonathan P., Gao, Bo, Fasching, Peter A., Beckmann, Matthias W., Lambrechts, Diether, Vergote, Ignace, Edwards, Digna R. Velez, Beeghly-Fadiel, Alicia, Benitez, Javier, Garcia, Maria J., Goodman, Marc T., Thompson, Pamela J., Dörk, Thilo, Dürst, Matthias, Modungo, Francesmary, Moysich, Kirsten, Heitz, Florian, du Bois, Andreas, Pfisterer, Jacobus, Hillemanns, Peter, Karlan, Beth Y., Lester, Jenny, Goode, Ellen L., Cunningham, Julie M., Winham, Stacey J. ... Chenevix-Trench, Georgia (2017). Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci. OncoTarget, 8 (39), 64670-64684. doi: 10.18632/oncotarget.18501 |
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2016 Journal Article Five endometrial cancer risk loci identified through genome-wide association analysisCheng, Timothy H. T., Thompson, Deborah J., O'Mara, Tracy A., Painter, Jodie N., Glubb, Dylan M., Flach, Susanne, Lewis, Annabelle, French, Juliet D., Freeman-Mills, Luke, Church, David, Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Webb, Penelope M., Attia, John, Holliday, Elizabeth G., McEvoy, Mark, Scott, Rodney J., Henders, Anjali K., Martin, Nicholas G., Montgomery, Grant W., Nyholt, Dale R., Ahmed, Shahana, Healey, Catherine S., Shah, Mitul, Dennis, Joe, Fasching, Peter A., Beckmann, Matthias W., Hein, Alexander ... Spurdle, Amanda B. (2016). Five endometrial cancer risk loci identified through genome-wide association analysis. Nature Genetics, 48 (6), 667-674. doi: 10.1038/ng.3562 |
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2016 Journal Article CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancerThompson, Deborah J., O'Mara, Tracy A., Glubb, Dylan M., Painter, Jodie N., Cheng, Timothy, Folkerd, Elizabeth, Doody, Deborah, Dennis, Joe, Webb, Penelope M., Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Michailidou, Kyriaki, Tyrer, Jonathan P., Maranian, Mel J., Hall, Per, Czene, Kamila, Darabi, Hatef, Li, Jingmei, Fasching, Peter A., Hein, Alexander, Beckmann, Matthias W., Ekici, Arif B., Doerk, Thilo, Hillemanns, Peter, Duerst, Matthias, Runnebaum, Ingo, Zhao, Hui, Depreeuw, Jeroen ... Spurdle, Amanda B. (2016). CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer. Endocrine-Related Cancer, 23 (2), 77-91. doi: 10.1530/ERC-15-0386 |
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2015 Journal Article Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancerO'Mara, Tracy A., Glubb, Dylan M., Painter, Jodie N., Cheng, Timothy, Dennis, Joe, Attia, John, Holliday, Elizabeth G., McEvoy, Mark, Scott, Rodney J., Ashton, Katie, Proietto, Tony, Otton, Geoffrey, Shah, Mitul, Ahmed, Shahana, Healey, Catherine S., Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Fasching, Peter A., Hein, Alexander, Beckmann, Matthias W., Ekici, Arif B., Hall, Per, Czene, Kamila, Darabi, Hatef, Li, Jingmei, Duerst, Matthias, Runnebaum, Ingo, Hillemanns, Peter ... Spurdle, Amanda B. (2015). Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer. Endocrine-Related Cancer, 22 (5), 851-861. doi: 10.1530/ERC-15-0319 |
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2015 Journal Article Long-range modulation of PAG1 expression by 8q21 allergy risk variantsVicente, Cristina T., Edwards, Stacey L., Hillman, Kristine M., Kaufmann, Susanne, Mitchell, Hayley, Bain, Lisa, Glubb, Dylan M., Lee, Jason S., French, Juliet D. and Ferreira, Manuel A. R. (2015). Long-range modulation of PAG1 expression by 8q21 allergy risk variants. American Journal of Human Genetics, 97 (2) 1909, 329-336. doi: 10.1016/j.ajhg.2015.06.010 |
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2015 Journal Article Functional FLT1 genetic variation is a prognostic factor for recurrence in Stage I-III non-small-cell lung cancerGlubb, Dylan M., Paré-Brunet, Laia, Jantus-Lewintre, Eloisa, Jiang, Chen, Crona, Daniel, Etheridge, Amy S., Mirza, Osman, Zhang, Wei, Seiser, Eric L., Rzyman, Witold, Jassem, Jacek, Auman, Todd, Hirsch, Fred R., Owzar, Kouros, Camps, Carlos, Dziadziuszko, Rafal and Innocenti, Federico (2015). Functional FLT1 genetic variation is a prognostic factor for recurrence in Stage I-III non-small-cell lung cancer. Journal of Thoracic Oncology, 10 (7), 1067-1075. doi: 10.1097/JTO.0000000000000549 |
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2015 Journal Article Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1Glubb, Dylan, Maranian, Mel J., Michailidou, Kyriaki, Pooley, Karen A., Meyer, Kerstin, Kar, Siddhartha, Carlebur, Saskia, O'Reilly, Martin, Betts, Joshua A., Hillman, Kristine M., Kaufmann, Susanne, Beesley, Jonathan, Canisius, Sander, Hopper, John L., Southey, Melissa C., Tsimiklis, Helen, Apicella, Carmel, Schmidt, Marjanka K., Broeks, Annegien, Hogervorst, Frans B., van der Schoot, C. Ellen, Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Fasching, Peter, Ruebner, Matthias, Ekici, Arif B., Beckmann, Matthias W. ... French, Juliet D. (2015). Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1. American Journal of Human Genetics, 96 (1), 5-20. doi: 10.1016/j.ajhg.2014.11.009 |
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2014 Journal Article Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulationGhoussaini, Maya, Edwards, Stacey L., Michailidou, Kyriaki, Nord, Silje, Lari, Richard Cowper-Sal, Desai, Kinjal, Kar, Siddhartha, Hillman, Kristine M., Kaufmann, Susanne, Glubb, Dylan M., Beesley, Jonathan, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Guo, Qi, Schmidt, Marjanka K., Shah, Mitul, Luben, Robert, Brown, Judith, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Bojesen, Stig E., Nordestgaard, Borge G., Nielsen, Sune F., Flyger, Henrik, Lambrechts, Diether ... Dunning, Alison M. (2014). Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications, 5 (1) 4999, 4999.1-4999.12. doi: 10.1038/ncomms5999 |
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2014 Book Chapter Liver Expression Quantitative Trait Loci (eQTL) and Related Approaches in Pharmacogenomic StudiesGlubb, Dylan M., Etheridge, Amy S., Seiser, Eric and Innocenti, Federico (2014). Liver Expression Quantitative Trait Loci (eQTL) and Related Approaches in Pharmacogenomic Studies. Handbook of Pharmacogenomics and Stratified Medicine. (pp. 111-123) Elsevier Inc.. doi: 10.1016/B978-0-12-386882-4.00007-4 |
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2014 Journal Article Discovery and functional assessment of gene variants in the vascular endothelial growth factor pathwayParé-Brunet, Laia, Glubb, Dylan, Evans, Patrick, Berenguer-Llergo, Antoni, Etheridge, Amy S., Skol, Andrew D., Di Rienzo, Anna, Duan, Shiwei, Gamazon, Eric R. and Innocenti, Federico (2014). Discovery and functional assessment of gene variants in the vascular endothelial growth factor pathway. Human Mutation, 35 (2), 227-235. doi: 10.1002/humu.22475 |
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2013 Journal Article A guide to the current web-based resources in pharmacogenomicsGlubb, Dylan M., Paugh, Steven W., Van Schaik, Ron H. N. and Innocenti, Federico (2013). A guide to the current web-based resources in pharmacogenomics. Methods in Molecular Biology, 1015, 293-310. doi: 10.1007/978-1-62703-435-7_19 |
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2013 Journal Article Architecture of pharmacogenomic associations: Structures with functional foundations or castles made of sand?Glubb, Dylan M. and Innocenti, Federico (2013). Architecture of pharmacogenomic associations: Structures with functional foundations or castles made of sand?. Pharmacogenomics, 14 (1), 1-4. doi: 10.2217/pgs.12.188 |
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2012 Journal Article Liver expression quantitative trait loci: A foundation for pharmacogenomic researchGlubb, Dylan M., Dholakia, Neepa and Innocenti, Federico (2012). Liver expression quantitative trait loci: A foundation for pharmacogenomic research. Frontiers in Genetics, 3 (AUG) Article 153. doi: 10.3389/fgene.2012.00153 |
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2012 Journal Article A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303Innocenti, Federico, Owzar, Kouros, Cox, Nancy L., Evans, Patrick, Kubo, Michiaki, Zembutsu, Hitoshi, Jiang, Chen, Hollis, Donna, Mushiroda, Taisei, Li, Liang, Friedman, Paula, Wang, Liewei, Glubb, Dylan, Hurwitz, Herbert, Giacomini, Kathleen M., McLeod, Howard L., Goldberg, Richard M., Schilsky, Richard L., Kindler, Hedy L., Nakamura, Yusuke and Ratain, Mark J. (2012). A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. Clinical Cancer Research, 18 (2), 577-584. doi: 10.1158/1078-0432.CCR-11-1387 |
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2011 Journal Article Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancerGlubb, Dylan M., Cerri, Elisa, Giese, Alexandra, Zhang, Wei, Mirza, Osman, Thompson, Emma E., Chen, Peixian, Das, Soma, Jassem, Jacek, Rzyman, Witold, Lingen, Mark W., Salgia, Ravi, Hirsch, Fred R., Dziadziuszko, Rafal, Ballmer-Hofer, Kurt and Innocenti, Federico (2011). Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer. Clinical Cancer Research, 17 (16), 5257-5267. doi: 10.1158/1078-0432.CCR-11-0379 |
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2011 Journal Article Mechanisms of genetic regulation in gene expression: Examples from drug metabolizing enzymes and transportersGlubb, Dylan M. and Innocenti, Federico (2011). Mechanisms of genetic regulation in gene expression: Examples from drug metabolizing enzymes and transporters. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 3 (3), 299-313. doi: 10.1002/wsbm.125 |