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2018

Journal Article

Erratum: Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (Nature communications (2014) 4 (4999))

Ghoussaini, Maya, Edwards, Stacey L., Michailidou, Kyriaki, Nord, Silje, Cowper-Sal Lari, Richard, Desai, Kinjal, Kar, Siddhartha, Hillman, Kristine M., Kaufmann, Susanne, Glubb, Dylan M., Beesley, Jonathan, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Guo, Qi, Schmidt, Marjanka K., Shah, Mitul, Luben, Robert, Brown, Judith, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Bojesen, Stig E., Nordestgaard, Børge G, Nielsen, Sune F., Flyger, Henrik, Lambrechts, Diether ... Dunning, Alison M. (2018). Erratum: Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (Nature communications (2014) 4 (4999)). Nature communications, 9 (1) 16193. doi: 10.1038/ncomms16193

Erratum: Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (Nature communications (2014) 4 (4999))

2017

Journal Article

Enhancing the Promise of Drug Repositioning through Genetics

Pritchard, Jayne-Louise E., O’Mara, Tracy A. and Glubb, Dylan M. (2017). Enhancing the Promise of Drug Repositioning through Genetics. Frontiers in Pharmacology, 8 (DEC) 896. doi: 10.3389/fphar.2017.00896

Enhancing the Promise of Drug Repositioning through Genetics

2017

Journal Article

Association analysis identifies 65 new breast cancer risk loci

Michailidou, Kyriaki, Lindström, Sara, Dennis, Joe, Beesley, Jonathan, Hui, Shirley, Kar, Siddhartha, Lemaçon, Audrey, Soucy, Penny, Glubb, Dylan, Rostamianfar, Asha, Bolla, Manjeet K, Wang, Qin, Tyrer, Jonathan, Dicks, Ed, Lee, Andrew, Wang, Zhaoming, Allen, Jamie, Keeman, Renske, Eilber, Ursula, French, Juliet D, Qing Chen, Xiao, Fachal, Laura, McCue, Karen, McCart Reed, Amy E, Ghoussaini, Maya, Carroll, Jason S, Jiang, Xia, Finucane, Hilary, Adams, Marcia ... Easton, Douglas F (2017). Association analysis identifies 65 new breast cancer risk loci. Nature, 551 (7678), 92-94. doi: 10.1038/nature24284

Association analysis identifies 65 new breast cancer risk loci

2017

Journal Article

The association of CYP19A1 variation with circulating estradiol and aromatase inhibitor outcome: Can CYP19A1 variants be used to predict treatment efficacy?

Glubb, Dylan M., O'Mara, Tracy A., Shamsani, Jannah and Spurdle, Amanda B. (2017). The association of CYP19A1 variation with circulating estradiol and aromatase inhibitor outcome: Can CYP19A1 variants be used to predict treatment efficacy?. Frontiers in Pharmacology, 8 (April) 218, 1-8. doi: 10.3389/fphar.2017.00218

The association of CYP19A1 variation with circulating estradiol and aromatase inhibitor outcome: Can CYP19A1 variants be used to predict treatment efficacy?

2017

Journal Article

Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci

Glubb, Dylan M., Johnatty, Sharon E., Quinn, Michael C. J., O'Mara, Tracy A., Tyrer, Jonathan P., Gao, Bo, Fasching, Peter A., Beckmann, Matthias W., Lambrechts, Diether, Vergote, Ignace, Edwards, Digna R. Velez, Beeghly-Fadiel, Alicia, Benitez, Javier, Garcia, Maria J., Goodman, Marc T., Thompson, Pamela J., Dörk, Thilo, Dürst, Matthias, Modungo, Francesmary, Moysich, Kirsten, Heitz, Florian, du Bois, Andreas, Pfisterer, Jacobus, Hillemanns, Peter, Karlan, Beth Y., Lester, Jenny, Goode, Ellen L., Cunningham, Julie M., Winham, Stacey J. ... Chenevix-Trench, Georgia (2017). Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci. OncoTarget, 8 (39), 64670-64684. doi: 10.18632/oncotarget.18501

Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci

2016

Journal Article

Five endometrial cancer risk loci identified through genome-wide association analysis

Cheng, Timothy H. T., Thompson, Deborah J., O'Mara, Tracy A., Painter, Jodie N., Glubb, Dylan M., Flach, Susanne, Lewis, Annabelle, French, Juliet D., Freeman-Mills, Luke, Church, David, Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Webb, Penelope M., Attia, John, Holliday, Elizabeth G., McEvoy, Mark, Scott, Rodney J., Henders, Anjali K., Martin, Nicholas G., Montgomery, Grant W., Nyholt, Dale R., Ahmed, Shahana, Healey, Catherine S., Shah, Mitul, Dennis, Joe, Fasching, Peter A., Beckmann, Matthias W., Hein, Alexander ... Spurdle, Amanda B. (2016). Five endometrial cancer risk loci identified through genome-wide association analysis. Nature Genetics, 48 (6), 667-674. doi: 10.1038/ng.3562

Five endometrial cancer risk loci identified through genome-wide association analysis

2016

Journal Article

CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer

Thompson, Deborah J., O'Mara, Tracy A., Glubb, Dylan M., Painter, Jodie N., Cheng, Timothy, Folkerd, Elizabeth, Doody, Deborah, Dennis, Joe, Webb, Penelope M., Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Michailidou, Kyriaki, Tyrer, Jonathan P., Maranian, Mel J., Hall, Per, Czene, Kamila, Darabi, Hatef, Li, Jingmei, Fasching, Peter A., Hein, Alexander, Beckmann, Matthias W., Ekici, Arif B., Doerk, Thilo, Hillemanns, Peter, Duerst, Matthias, Runnebaum, Ingo, Zhao, Hui, Depreeuw, Jeroen ... Spurdle, Amanda B. (2016). CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer. Endocrine-Related Cancer, 23 (2), 77-91. doi: 10.1530/ERC-15-0386

CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer

2015

Journal Article

Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer

O'Mara, Tracy A., Glubb, Dylan M., Painter, Jodie N., Cheng, Timothy, Dennis, Joe, Attia, John, Holliday, Elizabeth G., McEvoy, Mark, Scott, Rodney J., Ashton, Katie, Proietto, Tony, Otton, Geoffrey, Shah, Mitul, Ahmed, Shahana, Healey, Catherine S., Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Fasching, Peter A., Hein, Alexander, Beckmann, Matthias W., Ekici, Arif B., Hall, Per, Czene, Kamila, Darabi, Hatef, Li, Jingmei, Duerst, Matthias, Runnebaum, Ingo, Hillemanns, Peter ... Spurdle, Amanda B. (2015). Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer. Endocrine-Related Cancer, 22 (5), 851-861. doi: 10.1530/ERC-15-0319

Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer

2015

Journal Article

Long-range modulation of PAG1 expression by 8q21 allergy risk variants

Vicente, Cristina T., Edwards, Stacey L., Hillman, Kristine M., Kaufmann, Susanne, Mitchell, Hayley, Bain, Lisa, Glubb, Dylan M., Lee, Jason S., French, Juliet D. and Ferreira, Manuel A. R. (2015). Long-range modulation of PAG1 expression by 8q21 allergy risk variants. American Journal of Human Genetics, 97 (2) 1909, 329-336. doi: 10.1016/j.ajhg.2015.06.010

Long-range modulation of PAG1 expression by 8q21 allergy risk variants

2015

Journal Article

Functional FLT1 genetic variation is a prognostic factor for recurrence in Stage I-III non-small-cell lung cancer

Glubb, Dylan M., Paré-Brunet, Laia, Jantus-Lewintre, Eloisa, Jiang, Chen, Crona, Daniel, Etheridge, Amy S., Mirza, Osman, Zhang, Wei, Seiser, Eric L., Rzyman, Witold, Jassem, Jacek, Auman, Todd, Hirsch, Fred R., Owzar, Kouros, Camps, Carlos, Dziadziuszko, Rafal and Innocenti, Federico (2015). Functional FLT1 genetic variation is a prognostic factor for recurrence in Stage I-III non-small-cell lung cancer. Journal of Thoracic Oncology, 10 (7), 1067-1075. doi: 10.1097/JTO.0000000000000549

Functional FLT1 genetic variation is a prognostic factor for recurrence in Stage I-III non-small-cell lung cancer

2015

Journal Article

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1

Glubb, Dylan, Maranian, Mel J., Michailidou, Kyriaki, Pooley, Karen A., Meyer, Kerstin, Kar, Siddhartha, Carlebur, Saskia, O'Reilly, Martin, Betts, Joshua A., Hillman, Kristine M., Kaufmann, Susanne, Beesley, Jonathan, Canisius, Sander, Hopper, John L., Southey, Melissa C., Tsimiklis, Helen, Apicella, Carmel, Schmidt, Marjanka K., Broeks, Annegien, Hogervorst, Frans B., van der Schoot, C. Ellen, Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Fasching, Peter, Ruebner, Matthias, Ekici, Arif B., Beckmann, Matthias W. ... French, Juliet D. (2015). Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1. American Journal of Human Genetics, 96 (1), 5-20. doi: 10.1016/j.ajhg.2014.11.009

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1

2014

Journal Article

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

Ghoussaini, Maya, Edwards, Stacey L., Michailidou, Kyriaki, Nord, Silje, Lari, Richard Cowper-Sal, Desai, Kinjal, Kar, Siddhartha, Hillman, Kristine M., Kaufmann, Susanne, Glubb, Dylan M., Beesley, Jonathan, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Guo, Qi, Schmidt, Marjanka K., Shah, Mitul, Luben, Robert, Brown, Judith, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Bojesen, Stig E., Nordestgaard, Borge G., Nielsen, Sune F., Flyger, Henrik, Lambrechts, Diether ... Dunning, Alison M. (2014). Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications, 5 (1) 4999, 4999.1-4999.12. doi: 10.1038/ncomms5999

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

2014

Book Chapter

Liver Expression Quantitative Trait Loci (eQTL) and Related Approaches in Pharmacogenomic Studies

Glubb, Dylan M., Etheridge, Amy S., Seiser, Eric and Innocenti, Federico (2014). Liver Expression Quantitative Trait Loci (eQTL) and Related Approaches in Pharmacogenomic Studies. Handbook of Pharmacogenomics and Stratified Medicine. (pp. 111-123) Elsevier Inc.. doi: 10.1016/B978-0-12-386882-4.00007-4

Liver Expression Quantitative Trait Loci (eQTL) and Related Approaches in Pharmacogenomic Studies

2014

Journal Article

Discovery and functional assessment of gene variants in the vascular endothelial growth factor pathway

Paré-Brunet, Laia, Glubb, Dylan, Evans, Patrick, Berenguer-Llergo, Antoni, Etheridge, Amy S., Skol, Andrew D., Di Rienzo, Anna, Duan, Shiwei, Gamazon, Eric R. and Innocenti, Federico (2014). Discovery and functional assessment of gene variants in the vascular endothelial growth factor pathway. Human Mutation, 35 (2), 227-235. doi: 10.1002/humu.22475

Discovery and functional assessment of gene variants in the vascular endothelial growth factor pathway

2013

Journal Article

A guide to the current web-based resources in pharmacogenomics

Glubb, Dylan M., Paugh, Steven W., Van Schaik, Ron H. N. and Innocenti, Federico (2013). A guide to the current web-based resources in pharmacogenomics. Methods in Molecular Biology, 1015, 293-310. doi: 10.1007/978-1-62703-435-7_19

A guide to the current web-based resources in pharmacogenomics

2013

Journal Article

Architecture of pharmacogenomic associations: Structures with functional foundations or castles made of sand?

Glubb, Dylan M. and Innocenti, Federico (2013). Architecture of pharmacogenomic associations: Structures with functional foundations or castles made of sand?. Pharmacogenomics, 14 (1), 1-4. doi: 10.2217/pgs.12.188

Architecture of pharmacogenomic associations: Structures with functional foundations or castles made of sand?

2012

Journal Article

Liver expression quantitative trait loci: A foundation for pharmacogenomic research

Glubb, Dylan M., Dholakia, Neepa and Innocenti, Federico (2012). Liver expression quantitative trait loci: A foundation for pharmacogenomic research. Frontiers in Genetics, 3 (AUG) Article 153. doi: 10.3389/fgene.2012.00153

Liver expression quantitative trait loci: A foundation for pharmacogenomic research

2012

Journal Article

A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303

Innocenti, Federico, Owzar, Kouros, Cox, Nancy L., Evans, Patrick, Kubo, Michiaki, Zembutsu, Hitoshi, Jiang, Chen, Hollis, Donna, Mushiroda, Taisei, Li, Liang, Friedman, Paula, Wang, Liewei, Glubb, Dylan, Hurwitz, Herbert, Giacomini, Kathleen M., McLeod, Howard L., Goldberg, Richard M., Schilsky, Richard L., Kindler, Hedy L., Nakamura, Yusuke and Ratain, Mark J. (2012). A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. Clinical Cancer Research, 18 (2), 577-584. doi: 10.1158/1078-0432.CCR-11-1387

A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303

2011

Journal Article

Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer

Glubb, Dylan M., Cerri, Elisa, Giese, Alexandra, Zhang, Wei, Mirza, Osman, Thompson, Emma E., Chen, Peixian, Das, Soma, Jassem, Jacek, Rzyman, Witold, Lingen, Mark W., Salgia, Ravi, Hirsch, Fred R., Dziadziuszko, Rafal, Ballmer-Hofer, Kurt and Innocenti, Federico (2011). Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer. Clinical Cancer Research, 17 (16), 5257-5267. doi: 10.1158/1078-0432.CCR-11-0379

Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer

2011

Journal Article

Mechanisms of genetic regulation in gene expression: Examples from drug metabolizing enzymes and transporters

Glubb, Dylan M. and Innocenti, Federico (2011). Mechanisms of genetic regulation in gene expression: Examples from drug metabolizing enzymes and transporters. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 3 (3), 299-313. doi: 10.1002/wsbm.125

Mechanisms of genetic regulation in gene expression: Examples from drug metabolizing enzymes and transporters