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2019 Conference Publication Disclosing the bioactive surface of the potent NaV channel inhibitor ProTx-III [μ-TRTX-Tp1a]Zhao, Tianjiao, Rosengren, K. Johan, Cardoso, Fernanda C. and Lewis, Richard J. (2019). Disclosing the bioactive surface of the potent NaV channel inhibitor ProTx-III [μ-TRTX-Tp1a]. Brisbane Pain Research Symposium: Multidisciplinary Perspectives & Therapeutics 2019, Brisbane, QLD Australia, 29 November 2019. |
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2018 Journal Article Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profilingSlagboom, Julien, Otvos, Reka A., Cardoso, Fernanda C., Iyer, Janaki, Visser, Jeroen C., van Doodewaerd, Bjorn R., McCleary, Ryan J.R., Niessen, Wilfried M.A., Somsen, Govert W., Lewis, Richard J., Kini, R. Manjunatha, Smit, August B., Casewell, Nicholas R. and Kool, Jeroen (2018). Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profiling. Toxicon, 148, 213-222. doi: 10.1016/j.toxicon.2018.04.022 |
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2018 Journal Article Synthesis and evaluation of aminobenzothiazoles as blockers of N- and T-type calcium channelsSairaman, Anjali, Cardoso, Fernanda Caldas, Bispat, Anjie, Lewis, Richard J., Duggan, Peter J. and Tuck, Kellie L. (2018). Synthesis and evaluation of aminobenzothiazoles as blockers of N- and T-type calcium channels. Bioorganic and Medicinal Chemistry, 26 (11), 3046-3059. doi: 10.1016/j.bmc.2018.03.031 |
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2018 Journal Article Design, synthesis and biological profile of mixed opioid agonist/N-VGCC blocker peptidesStefanucci, Azzurra, Novelino, Ettore, Macedonio, Giorgia, Dimmito, Marilia Pia, Mirzaie, Sako, Cardoso, Fernanda Caldas , Lewis, Richard, Zador, Ferenc, Erdei, Anna I., Dvoracsko, Szabolcs, Tomboly, Csaba, Benych, Sandor, Pieretti, Stefano, Minosi, Paola and Mollica, Adriano (2018). Design, synthesis and biological profile of mixed opioid agonist/N-VGCC blocker peptides. New Journal of Chemistry, 42 (8), 5656-5659. doi: 10.1039/c7nj04969b |
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2018 Journal Article Toxins in painCardoso, Fernanda C., Hasan, Mahadhi, Zhao, Tianjiao and Lewis, Richard J. (2018). Toxins in pain. Current Opinion in Supportive and Palliative Care, 12 (2), 1-10. doi: 10.1097/SPC.0000000000000335 |
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2018 Conference Publication Counter screen of spider venoms reveals novel sodium and calcium channel inhibitors of chronic pain targets.Cardoso, F. C., Herzig, V., King, G. F. and Lewis, R. J. (2018). Counter screen of spider venoms reveals novel sodium and calcium channel inhibitors of chronic pain targets.. Gordon Research Conference on Venom Evolution, Function and Biomedical Applications 2018, Mount Snow, VT, United States, 5-10 August 2018. |
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2018 Conference Publication Can Phlo3a – a newly discovered spider knottin – meets the challenges to strategically modulate noxious Nav-channels?Dongol, Y., Cardoso, F. C. and Lewis, R. J. (2018). Can Phlo3a – a newly discovered spider knottin – meets the challenges to strategically modulate noxious Nav-channels?. Brisbane Pain Research: Multidisciplinary Perspectives & Therapeutics 2018, Brisbane, QLD, Australia, 7 December 2018. |
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2018 Conference Publication Disclosing the bioactive surface of the potent NaV channel inhibitor ProTx-III [μ-TRTX-Tp1a]Zhao, T., Cardoso, F.C. and Lewis, R.J. (2018). Disclosing the bioactive surface of the potent NaV channel inhibitor ProTx-III [μ-TRTX-Tp1a]. Brisbane Pain Research: Multidisciplinary Perspectives & Therapeutics 2018, Brisbane, QLD, Australia, 7 December 2018. |
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2018 Conference Publication Comparative analysis of transfection methods to establish high-throughput automated electrophysiology assays for key ion channels involved in painHasan, M.D., Cardoso, F.C. and Lewis, R.J. (2018). Comparative analysis of transfection methods to establish high-throughput automated electrophysiology assays for key ion channels involved in pain. Brisbane Pain Research: Multidisciplinary Perspectives & Therapeutics 2018, Brisbane, QLD, Australia, 7 December 2018. |
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2018 Conference Publication Jararhagin, a metalloproteinase from Bothrops jararaca venom, induces mechanical and thermal hyperalgesia through TRPV1 channel activationFerraz, C. R., Cardos, F. C., Clissa, P. B., Vetter, I., Verri Jr, W. A. and Lewis, R. J. (2018). Jararhagin, a metalloproteinase from Bothrops jararaca venom, induces mechanical and thermal hyperalgesia through TRPV1 channel activation. Brisbane Pain Research: Multidisciplinary Perspectives & Therapeutics 2018, Brisbane, QLD, Australia, 7 December 2018. |
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2017 Journal Article Sodium channels and pain: from toxins to therapiesCardoso, Fernanda Caldas and Lewis, Richard J. (2017). Sodium channels and pain: from toxins to therapies. British Journal of Pharmacology, 175 (12), 2138-2157. doi: 10.1111/bph.13962 |
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2017 Journal Article Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatusCardoso, Fernanda Caldas, Dekan, Zoltan, Smith, Jennifer J., Deuis, Jennifer R., Vetter, Irina, Herzig, Volker, Alewood, Paul F., King, Glenn F and Lewis, Richard J. (2017). Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus. British Journal of Pharmacology, 174 (15), 2528-2544. doi: 10.1111/bph.13865 |
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2017 Journal Article The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variantRahnama, Sassan, Deuis, Jennifer R., Cardoso, Fernanda C., Ramanujam, Venkatraman, Lewis, Richard J., Rash, Lachlan D., King, Glenn F., Vetter, Irina and Mobli, Mehdi (2017). The structure, dynamics and selectivity profile of a NaV 1.7 potency-optimised huwentoxin-IV variant. PLoS One, 12 (3) e0173551, e0173551. doi: 10.1371/journal.pone.0173551 |
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2017 Conference Publication High-throughput cell-based assays for screening Cav3.2 modulators from venomsWang, D., Herzig, V., Dekan, Z., Ragnarsson, Lotten K. N., Cardoso, Fernanda C. and Lewis, Richard J. (2017). High-throughput cell-based assays for screening Cav3.2 modulators from venoms. Venom to Drugs Conference 2017, Noosa Heads, QLD, Australia, 9-14 October 2017. |
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2017 Conference Publication Discovery of novel CaV and NaV modulators in spider venoms and applications in the development of drugs to treat chronic pain.Cardoso, Fernanda C., King, Glenn F. and Lewis, Richard J. (2017). Discovery of novel CaV and NaV modulators in spider venoms and applications in the development of drugs to treat chronic pain.. 19th World Congress of the International Society on Toxinology, Haikou City, Hainan Province, China, 24-31 October 2017. |
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2017 Conference Publication Defining ω-conotoxin binding site and delineating the role of the α2δ1 subunit in ω-conotoxin bindingHassan, Mahadhi, Abraham, Nikita, Ragnarsson, Lotten K.N., Cardoso, Fernanda C. and Lewis, Richard J. (2017). Defining ω-conotoxin binding site and delineating the role of the α2δ1 subunit in ω-conotoxin binding. Venom to Drugs Conference 2017, Noosa Heads, QLD Australia, 9-14 October 2017. |
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2017 Conference Publication Nav modulators in spider venoms and applications in the development of novel therapies for neurological disordersCardoso, Fernanda C., Bellingham, Mark C., King, Glenn F. and Lewis, Richard J. (2017). Nav modulators in spider venoms and applications in the development of novel therapies for neurological disorders. Venom to Drugs Conference 2017, Noosa Heads, QLD Australia, 9-14 October 2017. |
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2016 Journal Article Isolation and characterization of a structurally unique β-hairpin venom peptide from the predatory ant Anochetus emarginatusTouchard, Axel, Brust, Andreas, Cardoso, Fernanda C., Chin, K.-Y., Herzig, Volker, Jin, Ai-Hua, Dejean, Alain, Alewood, Paul F., King, Glenn F., Orivel, Jérôme and Escoubas, Pierre (2016). Isolation and characterization of a structurally unique β-hairpin venom peptide from the predatory ant Anochetus emarginatus. Biochimica et Biophysica Acta, 1860 (11 Part A), 2553-2562. doi: 10.1016/j.bbagen.2016.07.027 |
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2016 Conference Publication The inhibition of neuronal calcium channels with aminobenzothiazole derivativesSairaman, Anjali, Cardoso, Fernanda Caldas , Lewis, Richard J., Kaliappana, Krishna P., Tuck, Kellie L. and Duggan, Peter J. (2016). The inhibition of neuronal calcium channels with aminobenzothiazole derivatives. RACI Medicinal Chemistry and Chemical Biology Conference 2016, Coogee Beach, NSW, Australia, 7-9 November 2016. |
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2015 Journal Article The role of defensive ecological interactions in the evolution of conotoxinsPrashanth, J. R., Dutertre, S., Jin, A. H., Lavergne, V., Hamilton, B., Cardoso, F. C., Griffin, J., Venter, D. J., Alewood, P. F. and Lewis, R. J. (2015). The role of defensive ecological interactions in the evolution of conotoxins. Molecular Ecology, 25 (2), 598-615. doi: 10.1111/mec.13504 |
