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2019

Journal Article

Structure–function and therapeutic potential of spider venom-derived cysteine knot peptides targeting sodium channels

Cardoso, Fernanda C. and Lewis, Richard J. (2019). Structure–function and therapeutic potential of spider venom-derived cysteine knot peptides targeting sodium channels. Frontiers in Pharmacology, 10 (APR) 366, 366. doi: 10.3389/fphar.2019.00366

Structure–function and therapeutic potential of spider venom-derived cysteine knot peptides targeting sodium channels

2019

Journal Article

‘Messy’ Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency

Ziegman, Rebekah , Brust, Andreas , Jha, Prerna , Cardoso, Fernanda C. , Lewis, Richard J. and Alewood, Paul F. (2019). ‘Messy’ Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency. Marine Drugs, 17 (3) 165, 165. doi: 10.3390/md17030165

‘Messy’ Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency

2019

Conference Publication

Discovery of novel cav and nav modulators in spider venoms and applications in the development of drugs to treat chronic pain

Cardoso, Fernanda C., King, Glenn F. and Lewis, R. J. (2019). Discovery of novel cav and nav modulators in spider venoms and applications in the development of drugs to treat chronic pain. 19th World Congress of the International Society on Toxinology, Haikou City, Hainan Province, China, 24-31 October 2017. Oxford, United Kingdom: Elsevier.

Discovery of novel cav and nav modulators in spider venoms and applications in the development of drugs to treat chronic pain

2019

Conference Publication

New insights in ω-conotoxin analgesic efficacy in postsurgical pain and oxaliplatin/cisplatin induced peripheral neuropathy

Hasan, Mahadhi, Mueller, Alexander, Starobova, Hana, Vetter, Irina, Cardoso, Fernanda C. and Lewis, Richard J. (2019). New insights in ω-conotoxin analgesic efficacy in postsurgical pain and oxaliplatin/cisplatin induced peripheral neuropathy. Brisbane Pain Research Symposium: Multidisciplinary Perspectives & Therapeutics 2019, Brisbane, QLD Australia, 29 November 2019.

New insights in ω-conotoxin analgesic efficacy in postsurgical pain and oxaliplatin/cisplatin induced peripheral neuropathy

2019

Conference Publication

Harnessing multifunctional spider peptides to modulate pain pathways

Cardoso, Fernanda C. (2019). Harnessing multifunctional spider peptides to modulate pain pathways. International Society for Toxinology World Conference 2019, Buenos Aires, Argentina, 8-13 September 2019. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD.

Harnessing multifunctional spider peptides to modulate pain pathways

2019

Conference Publication

Rational design of spider knottin Phlo3a to strategically modulate multiple noxious NaV channels

Dongol, Yashad, Choi, Phil, Wilson, David, Cardoso, Fernanda C. and Lewis, Richards J. (2019). Rational design of spider knottin Phlo3a to strategically modulate multiple noxious NaV channels. Brisbane Pain Research Symposium: Multidisciplinary Perspectives & Therapeutics 2019, Brisbane, QLD, Australia, 29 November 2019.

Rational design of spider knottin Phlo3a to strategically modulate multiple noxious NaV channels

2019

Conference Publication

Characterization of δ-conotoxin Tx-VIA as selective T-type modulator

Wang, Dan, Himaya, S. W. A., Giacomotto, Jean, Hasan, Mahadhi, Cardoso, Fernanda C. and Lewis, Richard J. (2019). Characterization of δ-conotoxin Tx-VIA as selective T-type modulator. Brisbane Pain Research Symposium: Multidisciplinary Perspectives & Therapeutics 2019, Brisbane, QLD, Australia, 29 November 2019.

Characterization of δ-conotoxin Tx-VIA as selective T-type modulator

2019

Conference Publication

Disclosing the bioactive surface of the potent NaV channel inhibitor ProTx-III [μ-TRTX-Tp1a]

Zhao, Tianjiao, Rosengren, K. Johan, Cardoso, Fernanda C. and Lewis, Richard J. (2019). Disclosing the bioactive surface of the potent NaV channel inhibitor ProTx-III [μ-TRTX-Tp1a]. Brisbane Pain Research Symposium: Multidisciplinary Perspectives & Therapeutics 2019, Brisbane, QLD Australia, 29 November 2019.

Disclosing the bioactive surface of the potent NaV channel inhibitor ProTx-III [μ-TRTX-Tp1a]

2019

Conference Publication

Cooperative interactions of loops 1, 4 and C-terminal of the ICK spider peptide Tap1a engender NaV inhibitory properties

Mawlawi, Saja E., Zhao, Thianjiao, Lewis, Richard J. and Cardoso, Fernanda C. (2019). Cooperative interactions of loops 1, 4 and C-terminal of the ICK spider peptide Tap1a engender NaV inhibitory properties. Brisbane Pain Research Symposium: Multidisciplinary Perspectives & Therapeutics 2019, Brisbane, QLD Australia, 29 November 2019.

Cooperative interactions of loops 1, 4 and C-terminal of the ICK spider peptide Tap1a engender NaV inhibitory properties

2019

Conference Publication

Molecular interactions between spider toxins and the sodium channel Nav1.1

Hu, Huyiu, Lewis, Richard J. and Cardoso, Fernanda C. (2019). Molecular interactions between spider toxins and the sodium channel Nav1.1. Pain Retreat 2019, Stradbroke Island, QLD Australia, 27-29 May 2019.

Molecular interactions between spider toxins and the sodium channel Nav1.1

2019

Conference Publication

Structure-function relationships of spider venom neurotoxins: what are we learning from it?

Cardoso, Fernadna C. (2019). Structure-function relationships of spider venom neurotoxins: what are we learning from it?. Pain Retreat 2019, Stradbroke Island, QLD, Australia, 27-29 May 2019.

Structure-function relationships of spider venom neurotoxins: what are we learning from it?

2018

Journal Article

Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profiling

Slagboom, Julien, Otvos, Reka A., Cardoso, Fernanda C., Iyer, Janaki, Visser, Jeroen C., van Doodewaerd, Bjorn R., McCleary, Ryan J.R., Niessen, Wilfried M.A., Somsen, Govert W., Lewis, Richard J., Kini, R. Manjunatha, Smit, August B., Casewell, Nicholas R. and Kool, Jeroen (2018). Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profiling. Toxicon, 148, 213-222. doi: 10.1016/j.toxicon.2018.04.022

Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profiling

2018

Journal Article

Synthesis and evaluation of aminobenzothiazoles as blockers of N- and T-type calcium channels

Sairaman, Anjali, Cardoso, Fernanda Caldas, Bispat, Anjie, Lewis, Richard J., Duggan, Peter J. and Tuck, Kellie L. (2018). Synthesis and evaluation of aminobenzothiazoles as blockers of N- and T-type calcium channels. Bioorganic and Medicinal Chemistry, 26 (11), 3046-3059. doi: 10.1016/j.bmc.2018.03.031

Synthesis and evaluation of aminobenzothiazoles as blockers of N- and T-type calcium channels

2018

Journal Article

Design, synthesis and biological profile of mixed opioid agonist/N-VGCC blocker peptides

Stefanucci, Azzurra, Novelino, Ettore, Macedonio, Giorgia, Dimmito, Marilia Pia, Mirzaie, Sako, Cardoso, Fernanda Caldas , Lewis, Richard, Zador, Ferenc, Erdei, Anna I., Dvoracsko, Szabolcs, Tomboly, Csaba, Benych, Sandor, Pieretti, Stefano, Minosi, Paola and Mollica, Adriano (2018). Design, synthesis and biological profile of mixed opioid agonist/N-VGCC blocker peptides. New Journal of Chemistry, 42 (8), 5656-5659. doi: 10.1039/c7nj04969b

Design, synthesis and biological profile of mixed opioid agonist/N-VGCC blocker peptides

2018

Journal Article

Toxins in pain

Cardoso, Fernanda C., Hasan, Mahadhi, Zhao, Tianjiao and Lewis, Richard J. (2018). Toxins in pain. Current Opinion in Supportive and Palliative Care, 12 (2), 1-10. doi: 10.1097/SPC.0000000000000335

Toxins in pain

2018

Conference Publication

Disclosing the bioactive surface of the potent NaV channel inhibitor ProTx-III [μ-TRTX-Tp1a]

Zhao, T., Cardoso, F.C. and Lewis, R.J. (2018). Disclosing the bioactive surface of the potent NaV channel inhibitor ProTx-III [μ-TRTX-Tp1a]. Brisbane Pain Research: Multidisciplinary Perspectives & Therapeutics 2018, Brisbane, QLD, Australia, 7 December 2018.

Disclosing the bioactive surface of the potent NaV channel inhibitor ProTx-III [μ-TRTX-Tp1a]

2018

Conference Publication

Comparative analysis of transfection methods to establish high-throughput automated electrophysiology assays for key ion channels involved in pain

Hasan, M.D., Cardoso, F.C. and Lewis, R.J. (2018). Comparative analysis of transfection methods to establish high-throughput automated electrophysiology assays for key ion channels involved in pain. Brisbane Pain Research: Multidisciplinary Perspectives & Therapeutics 2018, Brisbane, QLD, Australia, 7 December 2018.

Comparative analysis of transfection methods to establish high-throughput automated electrophysiology assays for key ion channels involved in pain

2018

Conference Publication

Jararhagin, a metalloproteinase from Bothrops jararaca venom, induces mechanical and thermal hyperalgesia through TRPV1 channel activation

Ferraz, C. R., Cardos, F. C., Clissa, P. B., Vetter, I., Verri Jr, W. A. and Lewis, R. J. (2018). Jararhagin, a metalloproteinase from Bothrops jararaca venom, induces mechanical and thermal hyperalgesia through TRPV1 channel activation. Brisbane Pain Research: Multidisciplinary Perspectives & Therapeutics 2018, Brisbane, QLD, Australia, 7 December 2018.

Jararhagin, a metalloproteinase from Bothrops jararaca venom, induces mechanical and thermal hyperalgesia through TRPV1 channel activation

2018

Conference Publication

Counter screen of spider venoms reveals novel sodium and calcium channel inhibitors of chronic pain targets.

Cardoso, F. C., Herzig, V., King, G. F. and Lewis, R. J. (2018). Counter screen of spider venoms reveals novel sodium and calcium channel inhibitors of chronic pain targets.. Gordon Research Conference on Venom Evolution, Function and Biomedical Applications 2018, Mount Snow, VT, United States, 5-10 August 2018.

Counter screen of spider venoms reveals novel sodium and calcium channel inhibitors of chronic pain targets.

2018

Conference Publication

Can Phlo3a – a newly discovered spider knottin – meets the challenges to strategically modulate noxious Nav-channels?

Dongol, Y., Cardoso, F. C. and Lewis, R. J. (2018). Can Phlo3a – a newly discovered spider knottin – meets the challenges to strategically modulate noxious Nav-channels?. Brisbane Pain Research: Multidisciplinary Perspectives & Therapeutics 2018, Brisbane, QLD, Australia, 7 December 2018.

Can Phlo3a – a newly discovered spider knottin – meets the challenges to strategically modulate noxious Nav-channels?