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2024

Journal Article

Dicer-2 mutations in Aedes aegypti cells lead to a diminished antiviral function against Rift Valley fever virus and Bunyamwera virus infection

Dornbusch, Susann, Reuter, Melinda, Parry, Rhys H., Stern, Michael, Becker, Stefanie C. and Schnettler, Esther (2024). Dicer-2 mutations in Aedes aegypti cells lead to a diminished antiviral function against Rift Valley fever virus and Bunyamwera virus infection. Journal of General Virology, 105 (11) 002046. doi: 10.1099/jgv.0.002046

Dicer-2 mutations in Aedes aegypti cells lead to a diminished antiviral function against Rift Valley fever virus and Bunyamwera virus infection

2024

Journal Article

No evidence that mutations in SARS-CoV-2 variants of concern derive from homologous fragments in gut microbiota

Parry, Rhys H., Lytras, Spyros, Petrone, Mary E., Wille, Michelle, Crits-Christoph, Alexander, Gifford, Robert J., Saito, Akatsuki, Smura, Teemu and Peacock, Thomas P. (2024). No evidence that mutations in SARS-CoV-2 variants of concern derive from homologous fragments in gut microbiota. Journal of Virology, 98 (12), 1-2. doi: 10.1128/jvi.01468-24

No evidence that mutations in SARS-CoV-2 variants of concern derive from homologous fragments in gut microbiota

2024

Journal Article

Synthetic recovery of Yada Yada virus expands insect-specific alphavirus knowledge and facilitates production of chimeric viruses

Bell, Mikaela G., Parry, Rhys H., Lee, Tricia S. E., Habarugira, Gervais, McMahon, Isabella E., Thompson, Madeline A., Modhiran, Naphak, Watterson, Daniel, Batovska, Jana, Lynch, Stacey E., Hall, Roy A., Harrison, Jessica J. and Hobson-Peters, Jody (2024). Synthetic recovery of Yada Yada virus expands insect-specific alphavirus knowledge and facilitates production of chimeric viruses. npj Viruses, 2 (1) 45, 1-14. doi: 10.1038/s44298-024-00052-2

Synthetic recovery of Yada Yada virus expands insect-specific alphavirus knowledge and facilitates production of chimeric viruses

2024

Journal Article

Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts

Quek, Shannon, Hadermann, Amber, Wu, Yang, De Coninck, Lander, Hegde, Shrilakshmi, Boucher, Jordan R., Cresswell, Jessica, Foreman, Ella, Steven, Andrew, LaCourse, E. James, Ward, Stephen A., Wanji, Samuel, Hughes, Grant L., Patterson, Edward I., Wagstaff, Simon C., Turner, Joseph D., Parry, Rhys H., Kohl, Alain, Heinz, Eva, Otabil, Kenneth Bentum, Matthijnssens, Jelle, Colebunders, Robert and Taylor, Mark J. (2024). Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts. Nature Microbiology, 9 (10), 2488-2505. doi: 10.1038/s41564-024-01796-6

Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts

2024

Journal Article

Detection of Dengue virus 1 and mammalian orthoreovirus 3, with novel reassortments, in a South African family returning from Thailand, 2017

Jansen van Vuren, Petrus, Parry, Rhys H. and Pawęska, Janusz T. (2024). Detection of Dengue virus 1 and mammalian orthoreovirus 3, with novel reassortments, in a South African family returning from Thailand, 2017. Viruses, 16 (8) 1274, 1274. doi: 10.3390/v16081274

Detection of Dengue virus 1 and mammalian orthoreovirus 3, with novel reassortments, in a South African family returning from Thailand, 2017

2024

Journal Article

A ~40-kb flavi-like virus does not encode a known error-correcting mechanism

Petrone, Mary E., Grove, Joe, Mélade, Julien, Mifsud, Jonathon C. O., Parry, Rhys H., Marzinelli, Ezequiel M. and Holmes, Edward C. (2024). A ~40-kb flavi-like virus does not encode a known error-correcting mechanism. Proceedings of the National Academy of Sciences, 121 (30) e2403805121, e2403805121-30. doi: 10.1073/pnas.2403805121

A ~40-kb flavi-like virus does not encode a known error-correcting mechanism

2024

Journal Article

Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom

Hinds, Joseph, Apaa, Ternenge, Parry, Rhys H., Withers, Amy J., MacKenzie, Laura, Staley, Ceri, Morrison, Joshua, Bennett, Malcolm, Bremner-Harrison, Samantha, Chadwick, Elizabeth A., Hailer, Frank, Harrison, Stephen W.R., Lambin, Xavier, Loose, Mathew, Mathews, Fiona, Tarlinton, Rachael and Blanchard, Adam (2024). Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom. Access Microbiology, 6 (7) 000813.v4, 1-8. doi: 10.1099/acmi.0.000813.v4

Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom

2024

Journal Article

Xinyang flavivirus, from Haemaphysalis flava ticks in Henan Province, China, defines a basal, likely tick-only Orthoflavivirus clade

Wang, Lan-Lan, Cheng, Qia, Newton, Natalee D., Wolfinger, Michael T., Morgan, Mahali S., Slonchak, Andrii, Khromykh, Alexander A., Cheng, Tian-Yin and Parry, Rhys H. (2024). Xinyang flavivirus, from Haemaphysalis flava ticks in Henan Province, China, defines a basal, likely tick-only Orthoflavivirus clade. Journal of General Virology, 105 (5) 001991, 1-13. doi: 10.1099/jgv.0.001991

Xinyang flavivirus, from Haemaphysalis flava ticks in Henan Province, China, defines a basal, likely tick-only Orthoflavivirus clade

2024

Journal Article

A novel papillomavirus in a New Zealand fur seal (Arctocephalus forsteri) with oral lesions

Mifsud, Jonathon C. O., Hall, Jane, Van Brussel, Kate, Rose, Karrie, Parry, Rhys H., Holmes, Edward C. and Harvey, Erin (2024). A novel papillomavirus in a New Zealand fur seal (Arctocephalus forsteri) with oral lesions. npj Viruses, 2 (1) 10, 1-10. doi: 10.1038/s44298-024-00020-w

A novel papillomavirus in a New Zealand fur seal (Arctocephalus forsteri) with oral lesions

2023

Journal Article

A novel tamanavirus (Flaviviridae) of the European common frog (Rana temporaria) from the UK

Parry, Rhys H., Slonchak, Andrii, Campbell, Lewis J., Newton, Natalee D., Debat, Humberto J., Gifford, Robert J. and Khromykh, Alexander A. (2023). A novel tamanavirus (Flaviviridae) of the European common frog (Rana temporaria) from the UK. Journal of General Virology, 104 (12) 001927, 1-12. doi: 10.1099/jgv.0.001927

A novel tamanavirus (Flaviviridae) of the European common frog (Rana temporaria) from the UK

2023

Journal Article

The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant

Pegg, Cassandra L., Modhiran, Naphak, Parry, Rhys H., Liang, Benjamin, Amarilla, Alberto A., Khromykh, Alexander A., Burr, Lucy, Young, Paul R., Chappell, Keith, Schulz, Benjamin L. and Watterson, Daniel (2023). The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant. Glycobiology, 34 (2) cwad097, 1-13. doi: 10.1093/glycob/cwad097

The role of N-glycosylation in spike antigenicity for the SARS-CoV-2 gamma variant

2023

Journal Article

SARS-CoV-2 omicron BA.5 and XBB variants have increased neurotropic potential over BA.1 in K18-hACE2 mice and human brain organoids

Stewart, Romal, Yan, Kexin, Ellis, Sevannah A., Bishop, Cameron R., Dumenil, Troy, Tang, Bing, Nguyen, Wilson, Larcher, Thibaut, Parry, Rhys, Sng, Julian De Jun, Khromykh, Alexander A., Sullivan, Robert K. P., Lor, Mary, Meunier, Frédéric A., Rawle, Daniel J. and Suhrbier, Andreas (2023). SARS-CoV-2 omicron BA.5 and XBB variants have increased neurotropic potential over BA.1 in K18-hACE2 mice and human brain organoids. Frontiers in Microbiology, 14 1320856, 1-18. doi: 10.3389/fmicb.2023.1320856

SARS-CoV-2 omicron BA.5 and XBB variants have increased neurotropic potential over BA.1 in K18-hACE2 mice and human brain organoids

2023

Journal Article

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Aguado, Julio, Amarilla, Alberto A., Taherian Fard, Atefeh, Albornoz, Eduardo A., Tyshkovskiy, Alexander, Schwabenland, Marius, Chaggar, Harman K., Modhiran, Naphak, Gómez-Inclán, Cecilia, Javed, Ibrahim, Baradar, Alireza A., Liang, Benjamin, Peng, Lianli, Dharmaratne, Malindrie, Pietrogrande, Giovanni, Padmanabhan, Pranesh, Freney, Morgan E., Parry, Rhys, Sng, Julian D. J., Isaacs, Ariel, Khromykh, Alexander A., Valenzuela Nieto, Guillermo, Rojas-Fernandez, Alejandro, Davis, Thomas P., Prinz, Marco, Bengsch, Bertram, Gladyshev, Vadim N., Woodruff, Trent M., Mar, Jessica C. ... Wolvetang, Ernst J. (2023). Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology. Nature Aging, 3 (12), 1561-1575. doi: 10.1038/s43587-023-00519-6

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

2023

Journal Article

Evidence for an ancient aquatic origin of the RNA viral order Articulavirales

Petrone, Mary E., Parry, Rhys, Mifsud, Jonathon C. O., Van Brussel, Kate, Vorhees, Ian, Richards, Zoe T. and Holmes, Edward C. (2023). Evidence for an ancient aquatic origin of the RNA viral order Articulavirales. Proceedings of the National Academy of Sciences, 120 (45) e2310529120, 1-10. doi: 10.1073/pnas.2310529120

Evidence for an ancient aquatic origin of the RNA viral order Articulavirales

2023

Journal Article

Egg protein profile and dynamics during embryogenesis in Haemaphysalis flava ticks

Cheng, Rong, Li, Dan, Duan, De-yong, Parry, Rhys, Cheng, Tian-yin and Liu, Lei (2023). Egg protein profile and dynamics during embryogenesis in Haemaphysalis flava ticks. Ticks and Tick-borne Diseases, 14 (4) 102180, 1-9. doi: 10.1016/j.ttbdis.2023.102180

Egg protein profile and dynamics during embryogenesis in Haemaphysalis flava ticks

2023

Journal Article

Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery

Edwards, Mark R., Forbes, Gordon, Walker, Neil, Morton, Dion G., Mythen, Monty G., Murray, Dave, Anderson, Iain, Mihaylova, Borislava, Thomson, Ann, Taylor, Matt, Hollyman, Marianne, Phillips, Rachel, Young, Keith, Kahan, Brennan C., Pearse, Rupert M., Grocott, Michael P. W., Skubala, Alexandra, Tapley, Patrick, Kellett, Suzanne, Bolger, Clare, Burnish, Rachel, Collings, Nikki, Cumpstey, Andrew, Wong, Hannah, Rehnberg, Vic, Lees, Jessica, Salmon, Karen, Wee, Naomi, Harrison, Sarah ... Brennan, Christopher (2023). Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery. Trials, 24 (1) 313, 1-16. doi: 10.1186/s13063-023-07275-3

Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery

2023

Journal Article

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”. Journal of Virology, 97 (5) e0045123, 1-3. doi: 10.1128/jvi.00451-23

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

2023

Journal Article

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”. mSphere, 8 (3) e0016523, 1-3. doi: 10.1128/msphere.00165-23

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

2023

Journal Article

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

Speck, Peter, Mackenzie, Jason, Bull, Rowena A., Slobedman, Barry, Drummer, Heidi, Fraser, Johanna, Herrero, Lara, Helbig, Karla, Londrigan, Sarah, Moseley, Gregory, Prow, Natalie, Hansman, Grant, Edwards, Robert, Ahlenstiel, Chantelle, Abendroth, Allison, Tscharke, David, Hobson-Peters, Jody, Kriiger-Loterio, Robson, Parry, Rhys, Marsh, Glenn, Harding, Emma, Jacques, David A., Gartner, Matthew J., Lee, Wen Shi, McAuley, Julie, Vaz, Paola, Sainsbury, Frank, Tate, Michelle D., Sinclair, Jane ... Young, Paul (2023). Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”. mBio, 14 (3) e0081523, 1-3. doi: 10.1128/mbio.00815-23

Statement in Support of: “Virology under the Microscope—a Call for Rational Discourse”

Featured

2023

Journal Article

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

Albornoz, Eduardo A., Amarilla, Alberto A., Modhiran, Naphak, Parker, Sandra, Li, Xaria X., Wijesundara, Danushka K., Aguado, Julio, Zamora, Adriana Pliego, McMillan, Christopher L. D., Liang, Benjamin, Peng, Nias Y. G., Sng, Julian D. J., Saima, Fatema Tuj, Fung, Jenny N., Lee, John D., Paramitha, Devina, Parry, Rhys, Avumegah, Michael S., Isaacs, Ariel, Lo, Martin W., Miranda-Chacon, Zaray, Bradshaw, Daniella, Salinas-Rebolledo, Constanza, Rajapakse, Niwanthi W., Wolvetang, Ernst J., Munro, Trent P., Rojas-Fernandez, Alejandro, Young, Paul R., Stacey, Katryn J. ... Woodruff, Trent M. (2023). SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein. Molecular Psychiatry, 28 (7), 2878-2893. doi: 10.1038/s41380-022-01831-0

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein