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2016

Journal Article

An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1

Dutton, Julie L., Woo, Wai-Ping, Chandra, Janin, Xu, Yan, Li, Bo, Finlayson, Neil, Griffin, Paul and Frazer, Ian H. (2016). An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1. Human Vaccines and Immunotherapeutics, 12 (12), 3079-3088. doi: 10.1080/21645515.2016.1221872

An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1

2016

Journal Article

Epithelium expressing the E7 oncoprotein of HPV16 attracts immune-modulatory dendritic cells to the skin and suppresses their antigen-processing capacity

Chandra, Janin, Miao, Yan, Romoff, Natasha and Frazer, Ian H. (2016). Epithelium expressing the E7 oncoprotein of HPV16 attracts immune-modulatory dendritic cells to the skin and suppresses their antigen-processing capacity. Plos One, 11 (3) e0152886, e0152886. doi: 10.1371/journal.pone.0152886

Epithelium expressing the E7 oncoprotein of HPV16 attracts immune-modulatory dendritic cells to the skin and suppresses their antigen-processing capacity

2016

Conference Publication

Immunotherapy for persisting viral infection and associated cancer

Frazer, I, Mattarollo, S., Leggatt, G., Wells, J., Tuong, K., Kuo, P., Jazayeri, S., Lambert, P. and Chandra, J. (2016). Immunotherapy for persisting viral infection and associated cancer. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Immunotherapy for persisting viral infection and associated cancer

2013

Journal Article

Indoleamine 2,3-dioxygenase activity contributes to local immune suppression in the skin expressing human papillomavirus oncoprotein E7

Mittal, Deepak, Kassianos, Andrew. J, Tran, Lee S., Bergot, Anne-Sophie, Gosmann, Christina, Hofmann, Janin, Blumenthal, Antje, Leggatt, Graham R. and Frazer, Ian H. (2013). Indoleamine 2,3-dioxygenase activity contributes to local immune suppression in the skin expressing human papillomavirus oncoprotein E7. Journal of Investigative Dermatology, 133 (12), 2686-2694. doi: 10.1038/jid.2013.222

Indoleamine 2,3-dioxygenase activity contributes to local immune suppression in the skin expressing human papillomavirus oncoprotein E7

2011

Journal Article

Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation

Winnik, Stephan, Lohmann, Christine, Richter, Eva K., Schäfer, Nicola, Song, Wen-Liang, Leiber, Florian, Mocharla, Pavani, Hofmann, Janin, Klingenberg, Roland, Borén, Jan, Becher, Burkhard, FitzGerald, Garret A., Lüscher, Thomas F., Matter, Christian M. and Beer, Jürg H. (2011). Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation. European Heart Journal, 32 (20), 2573-2584. doi: 10.1093/eurheartj/ehq501

Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation

2011

Journal Article

NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses

Hofmann, Janin, Mair, Florian, Greter, Melanie, Schmidt-Supprian, Marc and Becher, Burkhard (2011). NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses. Journal of Experimental Medicine, 208 (9), 1917-1929. doi: 10.1084/jem.20110128

NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses

2010

Journal Article

Concomitant type I IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion

Frenz, Theresa, Waibler, Zoe, Hofmann, Janin, Hamdorf, Matthias, Lantermann, Markus, Reizis, Boris, Tovey, Michael G., Aichele, Peter, Sutter, Gerd and Kalinke, Ulrich (2010). Concomitant type I IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion. European Journal of Immunology, 40 (10), 2769-2777. doi: 10.1002/eji.201040453

Concomitant type I IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion

2010

Journal Article

SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis

Stein, Sokrates, Lohmann, Christine, Schaefer, Nicola, Hofmann, Janin, Rohrer, Lucia, Besler, Christian, Rothgiesser, Karin M., Becher, Burkhard, Hottiger, Michael O., Boren, Jan, McBurney, Michael W., Landmesser, Ulf, Luescher, Thomas F. and Matter, Christian M. (2010). SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis. European Heart Journal, 31 (18), 2301-2309. doi: 10.1093/eurheartj/ehq107

SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis

2010

Journal Article

Histamine H1 receptor promotes atherosclerotic lesion formation by increasing vascular permeability for low-density lipoproteins

Rozenberg, Izabela, Sluka, Susanna H. M., Rohrer, Lucia, Hofmann, Janin, Becher, Burkhard, Akhmedov, Alexander, Soliz, Jorge, Mocharla, Pavani, Boren, Jan, Johansen, Pal, Steffel, Jan, Watanabe, Takeshi, Luescher, Thomas F. and Tanner, Felix C. (2010). Histamine H1 receptor promotes atherosclerotic lesion formation by increasing vascular permeability for low-density lipoproteins. Arteriosclerosis Thrombosis and Vascular Biology, 30 (5), 923-U92. doi: 10.1161/ATVBAHA.109.201079

Histamine H1 receptor promotes atherosclerotic lesion formation by increasing vascular permeability for low-density lipoproteins

2010

Journal Article

B-cells need a proper house, whereas T-cells are happy in a cave: the dependence of lymphocytes on secondary lymphoid tissues during evolution

Hofmann, Janin, Greter, Melanie, Du Pasquier, Louis and Becher, Burkhard (2010). B-cells need a proper house, whereas T-cells are happy in a cave: the dependence of lymphocytes on secondary lymphoid tissues during evolution. Trends in Immunology, 31 (4), 144-153. doi: 10.1016/j.it.2010.01.003

B-cells need a proper house, whereas T-cells are happy in a cave: the dependence of lymphocytes on secondary lymphoid tissues during evolution

2009

Journal Article

Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity

Greter, Melanie, Hofmann, Janin and Becher, Burkhard (2009). Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity. PLoS Biology, 7 (5) e1000109, e1000109. doi: 10.1371/journal.pbio.1000109

Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity