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2026

Journal Article

Hidden Architecture of Resistance: The Extracellular Matrix in Melanoma’s Immune Landscape

Guan, Yimeng, Edny, Gisella, Chandra, Janin, Souza-Fonseca-Guimaraes, Fernando and Haass, Nikolas K. (2026). Hidden Architecture of Resistance: The Extracellular Matrix in Melanoma’s Immune Landscape. Seminars in Cancer Biology, 125, 1-19. doi: 10.1016/j.semcancer.2026.06.004

Hidden Architecture of Resistance: The Extracellular Matrix in Melanoma’s Immune Landscape

2026

Other Outputs

FCS files unmixed CD45-positive

Chandra, Janin and Wang, Huang (2026). FCS files unmixed CD45-positive. The University of Queensland. (Dataset) doi: 10.48610/4c4f95d

FCS files unmixed CD45-positive

2026

Other Outputs

Microbiome and serum protein raw data

Chandra, Janin and Wang, Huang (2026). Microbiome and serum protein raw data. The University of Queensland. (Dataset) doi: 10.48610/a8a2b66

Microbiome and serum protein raw data

2026

Other Outputs

Data and analysis code for study to assess predictors of response to checkpoint blockade: blood and microbiome analysis of cancer patients undergoing ICI therapy.

Chandra, Janin and Mehdi, Ahmed (2026). Data and analysis code for study to assess predictors of response to checkpoint blockade: blood and microbiome analysis of cancer patients undergoing ICI therapy.. The University of Queensland. (Dataset) doi: 10.48610/7f87aa4

Data and analysis code for study to assess predictors of response to checkpoint blockade: blood and microbiome analysis of cancer patients undergoing ICI therapy.

2026

Journal Article

Beyond the bench: teaching grant writing in immunotherapy training

Leggatt, Graham, Chandra, Janin, Chen, Zhian, Coleborn, Elaina, Janke, Cooper and Souza-Fonseca-Guimaraes, Fernando (2026). Beyond the bench: teaching grant writing in immunotherapy training. Trends in Immunology, 47 (6), 456-459. doi: 10.1016/j.it.2026.04.010

Beyond the bench: teaching grant writing in immunotherapy training

2025

Journal Article

Spatial analysis of HPV ‐associated cervical intraepithelial neoplastic tissues demonstrate distinct immune signatures associated with cervical cancer progression

Pavilion, Gianna, Vu, Hani, Xiong, Zherui, Dang, Thi Viet Trinh, O'Brien, Blake, Walsh, Michael, Causer, Andrew, Chandra, Janin, Nguyen, Quan and Frazer, Ian H. (2025). Spatial analysis of HPV ‐associated cervical intraepithelial neoplastic tissues demonstrate distinct immune signatures associated with cervical cancer progression. Journal of Pathology, 268 (2) path.70002, 200-214. doi: 10.1002/path.70002

Spatial analysis of HPV ‐associated cervical intraepithelial neoplastic tissues demonstrate distinct immune signatures associated with cervical cancer progression

2025

Journal Article

An α-specific PI3K inhibitor improves chemotherapy efficacy by inhibiting hepatic stellate cell activation in liver cancer

Ruan, Qi, Chen, Tao, Kim, Minwoo, Yang, Haotian, Sinha, Debottam, He, Yaowu, Burke, Lez, Wickramasuriya, Lashith, Cao, Lu, Yan, Weikang, Hooper, John, Wang, Haolu, Bridle, Kim, Chandra, Janin, Crawford, Darrell and Liang, Xiaowen (2025). An α-specific PI3K inhibitor improves chemotherapy efficacy by inhibiting hepatic stellate cell activation in liver cancer. Hepatology PMID 8302946. doi: 10.1097/hep.0000000000001639

An α-specific PI3K inhibitor improves chemotherapy efficacy by inhibiting hepatic stellate cell activation in liver cancer

2025

Journal Article

The Involvement of IL-34 in Inflammatory and Malignant Skin Diseases

Dang, Thi Viet Trinh, Mehdi, Ahmed M., Kumari, Snehlata, Khosrotehrani, Kiarash, Frazer, Ian H., Hume, David A. and Chandra, Janin (2025). The Involvement of IL-34 in Inflammatory and Malignant Skin Diseases. Journal of Investigative Dermatology, 145 (11), 1-13. doi: 10.1016/j.jid.2025.05.003

The Involvement of IL-34 in Inflammatory and Malignant Skin Diseases

2024

Journal Article

STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines

Jia, Wencong, Chandra, Janin, Teoh, Siok Min, Tolley, Lynn, Yang, Haotian, Tse, Brian W. C., Sokolowski, Kamil A., Liang, Xiaowen, Crawford, Darrell H. G., Steel, Jason C., Yu, Chengzhong, Roberts, Michael S., Frazer, Ian H., Chen, Yu, Wang, Haolu and Yu, Meihua (2024). STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines. Nano Letters, 24 (49), 1-10. doi: 10.1021/acs.nanolett.4c03846

STING nanoagonist boosts antitumor immunity of therapeutic DNA vaccines

2024

Journal Article

Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen‐processing‐presentation machinery and poor patient survival

Dang, Thi Viet Trinh, Gillinder, Kevin R., Nguyen, Quan, Mulay, Onkar, Vo, Tuan, Mehdi, Ahmed M., Zhou, Chenhao, Brooks, Andrew J., Leggatt, Graham R., Hume, David A., Frazer, Ian H. and Chandra, Janin (2024). Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen‐processing‐presentation machinery and poor patient survival. Clinical and Translational Immunology, 13 (12) e70018, 1-18. doi: 10.1002/cti2.70018

Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen‐processing‐presentation machinery and poor patient survival

2024

Journal Article

Spatial analysis of HPV associated cervical intraepithelial neoplastic tissues demonstrate distinct immune signatures associated with cervical cancer progression

Pavilion, Gianna, Vu, Hani, Xiong, Zherui, Dang, Thi Viet Trinh, Walsh, Michael, Causer, Andrew, Chandra, Janin, Nguyen, Quan and Frazer, Ian H. (2024). Spatial analysis of HPV associated cervical intraepithelial neoplastic tissues demonstrate distinct immune signatures associated with cervical cancer progression. doi: 10.1101/2024.10.02.611623

Spatial analysis of HPV associated cervical intraepithelial neoplastic tissues demonstrate distinct immune signatures associated with cervical cancer progression

2024

Conference Publication

Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells

Dang, Thi Viet Trinh, Gillinder, Kevin R., Nguyen, Quan, Mulay, Onkar, Vo, Tuan, Mehdi, Ahmed M., Zhou, Chenhao, Brooks, Andrew J., Asplett, Kiran, Leggatt, Graham R., Hume, David A., Frazer, Ian H. and Chandra, Janin (2024). Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells. AACR Special Conference in Cancer Research: Tumor Immunology and Immunotherapy, Boston, MA, United States, 18-21 October 2024. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.tumimm24-a001

Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells

2024

Journal Article

A phase Ib study to assess the safety of the human papillomavirus DNA vaccine (AMV002) in combination with durvalumab for HPV-associated oropharyngeal squamous cell carcinoma

Ladwa, Rahul, Chandra, Janin, Woo, Wai-Ping, Finlayson, Neil, Liu, Howard, McGrath, Margaret, See, Adrienne, Hughes, Brett G., Cooper, Caroline L., Jackson, Jim E., Dzienis, Marcin, Xu, Yan, Panizza, Benedict, Frazer, Ian and Porceddu, Sandro V. (2024). A phase Ib study to assess the safety of the human papillomavirus DNA vaccine (AMV002) in combination with durvalumab for HPV-associated oropharyngeal squamous cell carcinoma. Frontiers in Oncology, 14 1419258, 1-8. doi: 10.3389/fonc.2024.1419258

A phase Ib study to assess the safety of the human papillomavirus DNA vaccine (AMV002) in combination with durvalumab for HPV-associated oropharyngeal squamous cell carcinoma

2024

Journal Article

Characterization of the skin microbiome in normal and cutaneous squamous cell carcinoma affected cats and dogs

Bromfield, Jacoba I., Zaugg, Julian, Straw, Rodney C., Cathie, Julia, Krueger, Annika, Sinha, Debottam, Chandra, Janin, Hugenholtz, Philip and Frazer, Ian H. (2024). Characterization of the skin microbiome in normal and cutaneous squamous cell carcinoma affected cats and dogs. mSphere, 9 (4) e0055523, e0055523. doi: 10.1128/msphere.00555-23

Characterization of the skin microbiome in normal and cutaneous squamous cell carcinoma affected cats and dogs

2023

Journal Article

Targeting Staphylococcus aureus dominated skin dysbiosis in actinic keratosis to prevent the onset of cutaneous squamous cell carcinoma: Outlook for future therapies?

Bromfield, Jacoba Isobella, Hugenholtz, Philip, Frazer, Ian Hector, Khosrotehrani, Kiarash and Chandra, Janin (2023). Targeting Staphylococcus aureus dominated skin dysbiosis in actinic keratosis to prevent the onset of cutaneous squamous cell carcinoma: Outlook for future therapies?. Frontiers in Oncology, 13 1091379, 1091379. doi: 10.3389/fonc.2023.1091379

Targeting Staphylococcus aureus dominated skin dysbiosis in actinic keratosis to prevent the onset of cutaneous squamous cell carcinoma: Outlook for future therapies?

2022

Journal Article

HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer

Mehdi, Ahmed M., Zhou, Chenhao, Turrell, Gavin, Walpole, Euan, Porceddu, Sandro, Frazer, Ian H. and Chandra, Janin (2022). HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer. Cancer Gene Therapy, 30 (4), 1-12. doi: 10.1038/s41417-022-00577-9

HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer

2022

Conference Publication

Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity

Dang, T. V. T., Gillinder, K. G., Brooks, A. J., Asplett, K., Tolley, L. K., Hume, D. A., Leggatt, G. R., Frazer, I. H. and Chandra, J. (2022). Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity. 29th Annual Congress of the European-Society-of-Gene-and-Cell-Therapy (ESCGT), Edinburgh, United Kingdom, 11-14 October 2022. New Rochelle, NY United States: Mary Ann Liebert.

Gene-therapy based modulation of antigen-presenting cells within hyperproliferative epithelium to restore immunity

2022

Journal Article

Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene–environment associations

Muralidharan, Sachin, Ali, Sarah, Yang, Lilin, Badshah, Joshua, Zahir, Syeda Farah, Ali, Rubbiya A., Chandra, Janin, Frazer, Ian H., Thomas, Ranjeny and Mehdi, Ahmed M. (2022). Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene–environment associations. Scientific Reports, 12 (1) 18710, 1-19. doi: 10.1038/s41598-022-21988-6

Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene–environment associations

2022

Journal Article

Editorial: Cancer Immunotherapies: From Efficacy to Resistance Mechanisms

Chandra, Janin, Hansen, Morten, Labarriere, Nathalie, Marigo, Ilaria, Souza-Fonseca-Guimaraes, Fernando, Vujanovic, Lazar, Koguchi, Yoshinobu and Jacquelot, Nicolas (2022). Editorial: Cancer Immunotherapies: From Efficacy to Resistance Mechanisms. Frontiers in Immunology, 13 939789, 939789. doi: 10.3389/fimmu.2022.939789

Editorial: Cancer Immunotherapies: From Efficacy to Resistance Mechanisms

2022

Other Outputs

E.PAGE: A curated database and enrichment tool to predict gene modules associated with gene-environment interactions

Muralidharan, Sachin, Ali, Sarah, Yang, Lilin, Badshah, Joshua, Zahir, Farah, Ali, Rubbiya, Chandra, Janin, Thomas, Ranjeny and Mehdi, Ahmed M. (2022). E.PAGE: A curated database and enrichment tool to predict gene modules associated with gene-environment interactions. doi: 10.1101/2022.01.03.474848

E.PAGE: A curated database and enrichment tool to predict gene modules associated with gene-environment interactions