|
2021 Journal Article Acquisition of murine splenic myeloid cells for protein and gene expression profiling by advanced flow cytometry and CITE-seqRødahl, Inga, Gotley, James, Andersen, Stacey B., Yu, Meihua, Mehdi, Ahmed M., Christ, Angelika N., Hamilton-Williams, Emma E., Frazer, Ian H., Lukowski, Samuel W. and Chandra, Janin (2021). Acquisition of murine splenic myeloid cells for protein and gene expression profiling by advanced flow cytometry and CITE-seq. STAR Protocols, 2 (4) 100842, 1-27. doi: 10.1016/j.xpro.2021.100842 |
|
2021 Journal Article A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasiaTuong, Zewen K., Lukowski, Samuel W., Nguyen, Quan H., Chandra, Janin, Zhou, Chenhao, Gillinder, Kevin, Bashaw, Abate A., Ferdinand, John R., Stewart, Benjamin J., Teoh, Siok Min, Hanson, Sarah J., Devitt, Katharina, Clatworthy, Menna R., Powell, Joseph E. and Frazer, Ian H. (2021). A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia. iScience, 24 (11) 103326, 103326. doi: 10.1016/j.isci.2021.103326 |
|
2021 Journal Article Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cellsLukowski, Samuel W., Rodahl, Inga, Kelly, Samuel, Yu, Meihua, Gotley, James, Zhou, Chenhao, Millard, Susan, Andersen, Stacey B., Christ, Angelika N., Belz, Gabrielle, Frazer, Ian H. and Chandra, Janin (2021). Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells. iScience, 24 (5) 102402, 1-21. doi: 10.1016/j.isci.2021.102402 |
|
2021 Journal Article Immune-inhibitory gene expression is positively correlated with overall immune activity and predicts increased survival probability of cervical and head and neck cancer patientsBudhwani, Megha, Turrell, Gavin, Yu, Meihua, Frazer, Ian H., Mehdi, Ahmed M. and Chandra, Janin (2021). Immune-inhibitory gene expression is positively correlated with overall immune activity and predicts increased survival probability of cervical and head and neck cancer patients. Frontiers in Molecular Biosciences, 8 622643, 622643. doi: 10.3389/fmolb.2021.622643 |
|
2021 Journal Article Antigen nonspecific induction of distinct regulatory T cell states in oncogene-driven hyperproliferative skinZhou, Chenhao, Tuong, Zewen Kelvin, Lukowski, Samuel Wieslaw, Chandra, Janin and Frazer, Ian H. (2021). Antigen nonspecific induction of distinct regulatory T cell states in oncogene-driven hyperproliferative skin. ImmunoHorizons, 5 (2), 102-116. doi: 10.4049/immunohorizons.2100006 |
|
2021 Journal Article Manganese-doped silica-based nanoparticles promote the efficacy of antigen-specific immunotherapyChandra, Janin, Teoh, Siok Min, Kuo, Paula, Tolley, Lynn, Bashaw, Abate Assefa, Tuong, Zewen Kelvin, Liu, Yang, Chen, Zibin, Wells, James W., Yu, Chengzhong, Frazer, Ian H. and Yu, Meihua (2021). Manganese-doped silica-based nanoparticles promote the efficacy of antigen-specific immunotherapy. The Journal of Immunology, 206 (5), ji2000355-998. doi: 10.4049/jimmunol.2000355 |
|
2021 Book Chapter Therapeutic DNA Vaccine Against HPV16-Associated CancerYu, Meihua and Chandra, Janin (2021). Therapeutic DNA Vaccine Against HPV16-Associated Cancer. DNA Vaccines. (pp. 241-252) New York, NY United States: Humana Press. doi: 10.1007/978-1-0716-0872-2_13 |
|
2020 Journal Article Regulatory T-cells but not IL-10 impair cell-mediated immunity in HPV+ hyperplastic epitheliumBashaw, Abate Assefa, Zhou, Chenhao, Yu, Meihua, Tolley, Lynn, Leggatt, Graham R., Frazer, Ian H. and Chandra, Janin (2020). Regulatory T-cells but not IL-10 impair cell-mediated immunity in HPV+ hyperplastic epithelium. The Journal of Investigative Dermatology, 141 (5), 1264-1273.e3. doi: 10.1016/j.jid.2020.10.011 |
|
2020 Journal Article A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC)Chandra, J., Woo, W. P., Finlayson, N., Liu, H. Y., McGrath, M., Ladwa, R., Brauer, M., Xu, Y., Hanson, S., Panizza, B., Frazer, I. H. and Porceddu, Sandro V. (2020). A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC). Cancer Immunology, Immunotherapy, 70 (3), 743-753. doi: 10.1007/s00262-020-02720-7 |
|
2020 Journal Article Dysregulation of stemness pathways in HPV mediated cervical malignant transformation identifies potential oncotherapy targetsBudhwani, Megha, Lukowski, Samuel W., Porceddu, Sandro V., Frazer, Ian H. and Chandra, Janin (2020). Dysregulation of stemness pathways in HPV mediated cervical malignant transformation identifies potential oncotherapy targets. Frontiers in Cellular and Infection Microbiology, 10 307, 307. doi: 10.3389/fcimb.2020.00307 |
|
2019 Journal Article Immune responses to a HSV-2 polynucleotide immunotherapy COR-1 in HSV-2 positive subjects: a randomized double blinded phase I/IIa trialChandra, Janin, Woo, Wai-Ping, Dutton, Julie L., Xu, Yan, Li, Bo, Kinrade, Sally, Druce, Julian, Finlayson, Neil, Griffin, Paul, Laing, Kerry J., Koelle, David M. and Frazer, Ian H. (2019). Immune responses to a HSV-2 polynucleotide immunotherapy COR-1 in HSV-2 positive subjects: a randomized double blinded phase I/IIa trial. PLoS One, 14 (12) e0226320, 1-20. doi: 10.1371/journal.pone.0226320 |
|
2019 Journal Article HPV16 E7-driven epithelial hyperplasia promotes impaired antigen presentation and regulatory T cell developmentBashaw, Abate Assefa, Teoh, Siok M., Tuong, Zewen K., Leggatt, Graham R., Frazer, Ian H. and Chandra, Janin (2019). HPV16 E7-driven epithelial hyperplasia promotes impaired antigen presentation and regulatory T cell development. Journal of Investigative Dermatology, 139 (12), 2467-2476.e3. doi: 10.1016/j.jid.2019.03.1162 |
|
2019 Journal Article Immunotherapy for HPV associated cancerFrazer, Ian H. and Chandra, Janin (2019). Immunotherapy for HPV associated cancer. Papillomavirus Research, 8 100176, 100176. doi: 10.1016/j.pvr.2019.100176 |
|
2017 Journal Article CD8+ lineage dendritic cells determine adaptive immune responses to inflammasome activation upon sterile skin injuryChakraborty, Rituparna, Chandra, Janin, Cui, Shuai, Tolley, Lynn, Cooper, Matthew A., Kendall, Mark and Frazer, Ian H. (2017). CD8+ lineage dendritic cells determine adaptive immune responses to inflammasome activation upon sterile skin injury. Experimental Dermatology, 27 (1), 71-79. doi: 10.1111/exd.13436 |
|
2017 Journal Article Modulation of antigen presenting cell functions during chronic HPV infectionBashaw, Abate Assefa, Leggatt, Graham R., Chandra, Janin, Tuong, Zewen K. and Frazer, Ian H. (2017). Modulation of antigen presenting cell functions during chronic HPV infection. Papillomavirus Research, 4, 58-65. doi: 10.1016/j.pvr.2017.08.002 |
|
2017 Journal Article DNA vaccine encoding HPV16 oncogenes E6 and E7 induces potent cell-mediated and humoral immunity which protects in tumor challenge and drives E7-expressing skin graft rejectionChandra, Janin, Dutton, Julie L., Li, Bo, Woo, Wai-Ping, Xu, Yan, Tolley, Lynn K., Yong, Michelle, Wells, James W., Leggatt, Graham R., Finlayson, Neil and Frazer, Ian H. (2017). DNA vaccine encoding HPV16 oncogenes E6 and E7 induces potent cell-mediated and humoral immunity which protects in tumor challenge and drives E7-expressing skin graft rejection. Journal of Immunotherapy, 40 (2), 62-70. doi: 10.1097/CJI.0000000000000156 |
|
2016 Journal Article Batf3 selectively determines acquisition of CD8+ dendritic cell phenotype and functionChandra, Janin, Kuo, Paula T. Y., Hahn, Anne M., Belz, Gabrielle T. and Frazer, Ian H. (2016). Batf3 selectively determines acquisition of CD8+ dendritic cell phenotype and function. Immunology and Cell Biology, 95 (2), 215-223. doi: 10.1038/icb.2016.83 |
|
2016 Journal Article An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1Dutton, Julie L., Woo, Wai-Ping, Chandra, Janin, Xu, Yan, Li, Bo, Finlayson, Neil, Griffin, Paul and Frazer, Ian H. (2016). An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1. Human Vaccines and Immunotherapeutics, 12 (12), 3079-3088. doi: 10.1080/21645515.2016.1221872 |
|
2016 Journal Article Epithelium expressing the E7 oncoprotein of HPV16 attracts immune-modulatory dendritic cells to the skin and suppresses their antigen-processing capacityChandra, Janin, Miao, Yan, Romoff, Natasha and Frazer, Ian H. (2016). Epithelium expressing the E7 oncoprotein of HPV16 attracts immune-modulatory dendritic cells to the skin and suppresses their antigen-processing capacity. Plos One, 11 (3) e0152886, e0152886. doi: 10.1371/journal.pone.0152886 |
|
2016 Conference Publication Immunotherapy for persisting viral infection and associated cancerFrazer, I, Mattarollo, S., Leggatt, G., Wells, J., Tuong, K., Kuo, P., Jazayeri, S., Lambert, P. and Chandra, J. (2016). Immunotherapy for persisting viral infection and associated cancer. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
