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2019

Conference Publication

A recently identified ion channel in breast cancer

Bong, Alice H. L., Robitaille, Mélanie, Milevskiy, Michael J. G., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). A recently identified ion channel in breast cancer. AuPS/ASB Scientific meeting, Canberra, Australia, 1-4 December 2019.

A recently identified ion channel in breast cancer

2019

Conference Publication

Remodeling of calcium influx pathways in models of cancer associated fibroblasts in breast cancer

Monteith, Greg, Sadras, Francisco, Stewart, Teneale, Robitaille, Melanie, Kalita-de Croft, Priyakshi, Soon, Patsy, Saunus, Jodi, Lakhani, Sunil and Roberts-Thomson, Sarah (2019). Remodeling of calcium influx pathways in models of cancer associated fibroblasts in breast cancer. AACR Annual Meeting on Bioinformatics, Convergence Science, and Systems Biology, Atlanta, GA United States, 29 March - 3 April 2019. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-99

Remodeling of calcium influx pathways in models of cancer associated fibroblasts in breast cancer

2019

Conference Publication

Assessment of Ca2+ channels and pumps in brain-seeking breast cancer cell lines

Lim, Darren Z. R. , Chalmers, Silke B. , Robitaille, Melanie , Saunus, Jodi M. , Lakhani, Sunil R. , Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). Assessment of Ca2+ channels and pumps in brain-seeking breast cancer cell lines. ASCEPT-PAGANZ Joint Scientific Meeting, Queenstown, New Zealand, 25-29 November 2019. Hamilton Central, QLD, Australia: ASCEPT.

Assessment of Ca2+ channels and pumps in brain-seeking breast cancer cell lines

2018

Journal Article

A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties

Pavlovic, Zvezdan, Adams, Jarrett J., Blazer, Levi L., Gakhal, Amandeep K., Jarvik, Nick, Steinhart, Zachary, Robitaille, Melanie, Mascall, Keith, Pan, James, Angers, Stephane, Moffat, Jason and Sidhu, Sachdev S. (2018). A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties. mAbs, 10 (8), 1157-1167. doi: 10.1080/19420862.2018.1515565

A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties

2018

Journal Article

Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6m

Bassett, John J., Bong, Alice H.L., Janke, Ellen K., Robitaille, Mélanie, Roberts-Thomson, Sarah J., Peters, Amelia A. and Monteith, Gregory R. (2018). Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6m. Cell Calcium, 72, 39-50. doi: 10.1016/j.ceca.2018.02.003

Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6m

2018

Conference Publication

Cancer associated fibroblasts undergo a calcium channel switch

Sadras, Francisco, Stewart, Teneale A., Robitaille, Melanie, Kalita-de Croft, Priyakshi, Patsy, Soon, Saunus, Jodi M., Makhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2018). Cancer associated fibroblasts undergo a calcium channel switch. Australasian Society for Clinical and Experimental Pharmacologists and Toxicologists, Adelaide, SA, Australia, 27 - 30 November 2018.

Cancer associated fibroblasts undergo a calcium channel switch

2018

Conference Publication

Expression of calcium pumps, channels and channel regulators in a model of therapy resistance in melanoma

Chua, Chia C., Hammerlinde, Heinz, Robitaille, Melanie, Roberts-Thomson, Sarah J., Schauder, Helmut and Monteith, Gregory R. (2018). Expression of calcium pumps, channels and channel regulators in a model of therapy resistance in melanoma. Australasian Society for Clinical and Experimental Pharmacologists and Toxicologists, Adelaide, SA Australia, 27 - 30 November 2018.

Expression of calcium pumps, channels and channel regulators in a model of therapy resistance in melanoma

2017

Journal Article

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

Steinhart, Zachary, Pavlovic, Zvezdan, Chandrashekhar, Megha, Hart, Traver, Wang, Xiaowei, Zhang, Xiaoyu, Robitaille, Melanie, Browne, Kevin R., Jaksani, Sridevi, Overmeer, Rene, Boj, Sylvia F., Adams, Jarrett, Pan, James, Clevers, Hans, Sidhu, Sachdev, Moffat, Jason and Angers, Stephane (2017). Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors. Nature Medicine, 23 (1), 60-68. doi: 10.1038/nm.4219

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

2016

Journal Article

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells

Dey, A., Robitaille, M., Remke, M., Maier, C., Malhotra, A., Gregorieff, A., Wrana, J. L., Taylor, M. D., Angers, S. and Kenney, A. M. (2016). YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells. Oncogene, 35 (32), 4256-4268. doi: 10.1038/onc.2015.491

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells

2016

Journal Article

SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the G alpha i-LGN-NuMA Ternary Complex

Chiu, Catherine W. N., Monat, Carine, Robitaille, Melanie, Lacomme, Marine, Daulat, Avais M., Macleod, Graham, McNeill, Helen, Cayouette, Michel and Angers, Stephane (2016). SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the G alpha i-LGN-NuMA Ternary Complex. Developmental Cell, 36 (1), 50-62. doi: 10.1016/j.devcel.2015.12.016

SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the G alpha i-LGN-NuMA Ternary Complex

2015

Journal Article

Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling

Khan, Shahriar M., Min, Adam, Gora, Sarah, Houranieh, Geeda M., Campden, Rhiannon, Robitaille, Melanie, Trieu, Phan, Petrin, Darlaine, Jacobi, Ashley M., Behlke, Mark A., Angers, Stephane and Hebert, Terence E. (2015). Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling. Cellular Signalling, 27 (8), 1597-1608. doi: 10.1016/j.cellsig.2015.04.007

Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling

2015

Journal Article

BioID-based identification of SKP Cullin F-box (SCF)(beta-TrCP1/2) E3 ligase substrates

Coyaud, Etienne, Mis, Monika, Laurent, Estelle M. N., Dunham, Wade H., Couzens, Amber L., Robitaille, Melanie, Gingras, Anne-Claude, Angers, Stephane and Raught, Brian (2015). BioID-based identification of SKP Cullin F-box (SCF)(beta-TrCP1/2) E3 ligase substrates. Molecular & Cellular Proteomics, 14 (7), 1781-1795. doi: 10.1074/mcp.M114.045658

BioID-based identification of SKP Cullin F-box (SCF)(beta-TrCP1/2) E3 ligase substrates

2015

Journal Article

The identification of novel protein-protein interactions in liver that affect glucagon receptor activity

Han, Junfeng, Zhang, Ming, Froese, Sean, Dai, Feihan F., Robitaille, Melanie, Bhattacharjee, Alpana, Huang, Xinyi, Jia, Weiping, Angers, Stephane, Wheeler, Michael B. and Wei, Li (2015). The identification of novel protein-protein interactions in liver that affect glucagon receptor activity. Plos One, 10 (6), e0129226. doi: 10.1371/journal.pone.0129226

The identification of novel protein-protein interactions in liver that affect glucagon receptor activity

2015

Conference Publication

Sonic Hedgehog induces YB-1 in a yap-dependent manner to regulate Igf2 expression and proliferation in cerebellar granule neuron progenitors and medulloblastoma cells

Dey, A., Robitaille, M., Remke, M., Maier, C., Malhotra, A., Gregorieff, A., Wrana, J., Taylor, M., Angers, S. and Kenney, A. (2015). Sonic Hedgehog induces YB-1 in a yap-dependent manner to regulate Igf2 expression and proliferation in cerebellar granule neuron progenitors and medulloblastoma cells. 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, San Diego, CA United States, 7-8 May 2015. Cary, NC United States: Oxford University Press. doi: 10.1093/neuonc/nov061.78

Sonic Hedgehog induces YB-1 in a yap-dependent manner to regulate Igf2 expression and proliferation in cerebellar granule neuron progenitors and medulloblastoma cells

2015

Book Chapter

Tandem affinity purification to identify cytosolic and nuclear Gβγ-interacting proteins

Campden, Rhiannon, Petrin, Darlaine, Robitaille, Melanie, Audet, Nicolas, Gora, Sarah, Angers, Stephane and Hebert, Terence E. (2015). Tandem affinity purification to identify cytosolic and nuclear Gβγ-interacting proteins. Nuclear G-protein coupled receptors. (pp. 161-184) edited by Bruce G. Allen and Terence E. Hébert. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-1755-6_14

Tandem affinity purification to identify cytosolic and nuclear Gβγ-interacting proteins

2014

Journal Article

Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic beta cells

Zhang, Ming, Robitaille, Melanie, Showalter, Aaron D., Huang, Xinyi, Liu, Ying, Bhattacharjee, Alpana, Willard, Francis S., Han, Junfeng, Froese, Sean, Wei, Li, Gaisano, Herbert Y., Angers, Stephane, Sloop, Kyle W., Dai, Feihan F. and Wheeler, Michael B. (2014). Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic beta cells. Molecular and Cellular Proteomics, 13 (11), 3049-3062. doi: 10.1074/mcp.M114.040196

Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic beta cells

2014

Journal Article

Ubiquitylation and activation of a Rab GTPase is promoted by a beta(2)AR-HACE1 complex

Lachance, Veronik, Degrandmaison, Jade, Marois, Sebastien, Robitaille, Melanie, Genier, Samuel, Nadeau, Stephanie, Angers, Stephane and Parent, Jean-Luc (2014). Ubiquitylation and activation of a Rab GTPase is promoted by a beta(2)AR-HACE1 complex. Journal of Cell Science, 127 (1), 111-123. doi: 10.1242/jcs.132944

Ubiquitylation and activation of a Rab GTPase is promoted by a beta(2)AR-HACE1 complex

2013

Conference Publication

Transcriptional regulation at IGF2 promoters and mechanistic insights on induction of IGF2 downstream of yap in SHH medulloblastomas

Dev, Abhinav, Robitaille, Melanie, Remke, Marc, Faury, Damien, Maier, Caroline, Malhotra, Anshu, Jabado, Nada, Taylor, Michael, Angers, Stephane and Kenney, Anna (2013). Transcriptional regulation at IGF2 promoters and mechanistic insights on induction of IGF2 downstream of yap in SHH medulloblastomas. 4th Quadrennial Meeting of the World-Federation-of-Neuro-Oncology (WFNO) held in conjunction with the 18th Annual Meeting of the Society-for-Neuro-Oncology (SNO), San Francisco, CA United States, 21-24 November 2013. Cary, NC United States: Oxford University Press.

Transcriptional regulation at IGF2 promoters and mechanistic insights on induction of IGF2 downstream of yap in SHH medulloblastomas

2013

Journal Article

Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability

Roy, Sebastien J., Glazkova, Irina, Frechette, Louis, Iorio-Morin, Christian, Binda, Chantal, Petrin, Darlaine, Phan Trieu,, Robitaille, Melanie, Angers, Stephane, Hebert, Terence E. and Parent, Jean-Luc (2013). Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability. Molecular Endocrinology, 27 (8), 1245-1266. doi: 10.1210/me.2013-1091

Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability

2013

Conference Publication

Characterization of a novel protein interactor of galphai suggests its involvement in mitotic spindle orientation

Chiu, Catherine, Robitaille, Melanie, Daulat, Avais, Zhao, Peishen, Chidiac, Peter, Obiero, Josiah and Angers, Stephane (2013). Characterization of a novel protein interactor of galphai suggests its involvement in mitotic spindle orientation. GPCR 2012, -, 2012. London, United Kingdom: Taylor & Francis.

Characterization of a novel protein interactor of galphai suggests its involvement in mitotic spindle orientation