2019 Conference Publication A recently identified ion channel in breast cancerBong, Alice H. L., Robitaille, Mélanie, Milevskiy, Michael J. G., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). A recently identified ion channel in breast cancer. AuPS/ASB Scientific meeting, Canberra, Australia, 1-4 December 2019. |
2019 Conference Publication Remodeling of calcium influx pathways in models of cancer associated fibroblasts in breast cancerMonteith, Greg, Sadras, Francisco, Stewart, Teneale, Robitaille, Melanie, Kalita-de Croft, Priyakshi, Soon, Patsy, Saunus, Jodi, Lakhani, Sunil and Roberts-Thomson, Sarah (2019). Remodeling of calcium influx pathways in models of cancer associated fibroblasts in breast cancer. AACR Annual Meeting on Bioinformatics, Convergence Science, and Systems Biology, Atlanta, GA United States, 29 March - 3 April 2019. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS18-99 |
2019 Conference Publication Assessment of Ca2+ channels and pumps in brain-seeking breast cancer cell linesLim, Darren Z. R. , Chalmers, Silke B. , Robitaille, Melanie , Saunus, Jodi M. , Lakhani, Sunil R. , Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). Assessment of Ca2+ channels and pumps in brain-seeking breast cancer cell lines. ASCEPT-PAGANZ Joint Scientific Meeting, Queenstown, New Zealand, 25-29 November 2019. Hamilton Central, QLD, Australia: ASCEPT. |
2018 Journal Article A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor propertiesPavlovic, Zvezdan, Adams, Jarrett J., Blazer, Levi L., Gakhal, Amandeep K., Jarvik, Nick, Steinhart, Zachary, Robitaille, Melanie, Mascall, Keith, Pan, James, Angers, Stephane, Moffat, Jason and Sidhu, Sachdev S. (2018). A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties. mAbs, 10 (8), 1157-1167. doi: 10.1080/19420862.2018.1515565 |
2018 Journal Article Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6mBassett, John J., Bong, Alice H.L., Janke, Ellen K., Robitaille, Mélanie, Roberts-Thomson, Sarah J., Peters, Amelia A. and Monteith, Gregory R. (2018). Assessment of cytosolic free calcium changes during ceramide-induced cell death in MDA-MB-231 breast cancer cells expressing the calcium sensor GCaMP6m. Cell Calcium, 72, 39-50. doi: 10.1016/j.ceca.2018.02.003 |
2018 Conference Publication Cancer associated fibroblasts undergo a calcium channel switchSadras, Francisco, Stewart, Teneale A., Robitaille, Melanie, Kalita-de Croft, Priyakshi, Patsy, Soon, Saunus, Jodi M., Makhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2018). Cancer associated fibroblasts undergo a calcium channel switch. Australasian Society for Clinical and Experimental Pharmacologists and Toxicologists, Adelaide, SA, Australia, 27 - 30 November 2018. |
2018 Conference Publication Expression of calcium pumps, channels and channel regulators in a model of therapy resistance in melanomaChua, Chia C., Hammerlinde, Heinz, Robitaille, Melanie, Roberts-Thomson, Sarah J., Schauder, Helmut and Monteith, Gregory R. (2018). Expression of calcium pumps, channels and channel regulators in a model of therapy resistance in melanoma. Australasian Society for Clinical and Experimental Pharmacologists and Toxicologists, Adelaide, SA Australia, 27 - 30 November 2018. |
2017 Journal Article Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumorsSteinhart, Zachary, Pavlovic, Zvezdan, Chandrashekhar, Megha, Hart, Traver, Wang, Xiaowei, Zhang, Xiaoyu, Robitaille, Melanie, Browne, Kevin R., Jaksani, Sridevi, Overmeer, Rene, Boj, Sylvia F., Adams, Jarrett, Pan, James, Clevers, Hans, Sidhu, Sachdev, Moffat, Jason and Angers, Stephane (2017). Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors. Nature Medicine, 23 (1), 60-68. doi: 10.1038/nm.4219 |
2016 Journal Article YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cellsDey, A., Robitaille, M., Remke, M., Maier, C., Malhotra, A., Gregorieff, A., Wrana, J. L., Taylor, M. D., Angers, S. and Kenney, A. M. (2016). YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells. Oncogene, 35 (32), 4256-4268. doi: 10.1038/onc.2015.491 |
2016 Journal Article SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the G alpha i-LGN-NuMA Ternary ComplexChiu, Catherine W. N., Monat, Carine, Robitaille, Melanie, Lacomme, Marine, Daulat, Avais M., Macleod, Graham, McNeill, Helen, Cayouette, Michel and Angers, Stephane (2016). SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the G alpha i-LGN-NuMA Ternary Complex. Developmental Cell, 36 (1), 50-62. doi: 10.1016/j.devcel.2015.12.016 |
2015 Journal Article Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signallingKhan, Shahriar M., Min, Adam, Gora, Sarah, Houranieh, Geeda M., Campden, Rhiannon, Robitaille, Melanie, Trieu, Phan, Petrin, Darlaine, Jacobi, Ashley M., Behlke, Mark A., Angers, Stephane and Hebert, Terence E. (2015). Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling. Cellular Signalling, 27 (8), 1597-1608. doi: 10.1016/j.cellsig.2015.04.007 |
2015 Journal Article BioID-based identification of SKP Cullin F-box (SCF)(beta-TrCP1/2) E3 ligase substratesCoyaud, Etienne, Mis, Monika, Laurent, Estelle M. N., Dunham, Wade H., Couzens, Amber L., Robitaille, Melanie, Gingras, Anne-Claude, Angers, Stephane and Raught, Brian (2015). BioID-based identification of SKP Cullin F-box (SCF)(beta-TrCP1/2) E3 ligase substrates. Molecular & Cellular Proteomics, 14 (7), 1781-1795. doi: 10.1074/mcp.M114.045658 |
2015 Journal Article The identification of novel protein-protein interactions in liver that affect glucagon receptor activityHan, Junfeng, Zhang, Ming, Froese, Sean, Dai, Feihan F., Robitaille, Melanie, Bhattacharjee, Alpana, Huang, Xinyi, Jia, Weiping, Angers, Stephane, Wheeler, Michael B. and Wei, Li (2015). The identification of novel protein-protein interactions in liver that affect glucagon receptor activity. Plos One, 10 (6), e0129226. doi: 10.1371/journal.pone.0129226 |
2015 Conference Publication Sonic Hedgehog induces YB-1 in a yap-dependent manner to regulate Igf2 expression and proliferation in cerebellar granule neuron progenitors and medulloblastoma cellsDey, A., Robitaille, M., Remke, M., Maier, C., Malhotra, A., Gregorieff, A., Wrana, J., Taylor, M., Angers, S. and Kenney, A. (2015). Sonic Hedgehog induces YB-1 in a yap-dependent manner to regulate Igf2 expression and proliferation in cerebellar granule neuron progenitors and medulloblastoma cells. 3rd Biennial Conference on Pediatric Neuro-Oncology Basic and Translational Research, San Diego, CA United States, 7-8 May 2015. Cary, NC United States: Oxford University Press. doi: 10.1093/neuonc/nov061.78 |
2015 Book Chapter Tandem affinity purification to identify cytosolic and nuclear Gβγ-interacting proteinsCampden, Rhiannon, Petrin, Darlaine, Robitaille, Melanie, Audet, Nicolas, Gora, Sarah, Angers, Stephane and Hebert, Terence E. (2015). Tandem affinity purification to identify cytosolic and nuclear Gβγ-interacting proteins. Nuclear G-protein coupled receptors. (pp. 161-184) edited by Bruce G. Allen and Terence E. Hébert. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-1755-6_14 |
2014 Journal Article Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic beta cellsZhang, Ming, Robitaille, Melanie, Showalter, Aaron D., Huang, Xinyi, Liu, Ying, Bhattacharjee, Alpana, Willard, Francis S., Han, Junfeng, Froese, Sean, Wei, Li, Gaisano, Herbert Y., Angers, Stephane, Sloop, Kyle W., Dai, Feihan F. and Wheeler, Michael B. (2014). Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic beta cells. Molecular and Cellular Proteomics, 13 (11), 3049-3062. doi: 10.1074/mcp.M114.040196 |
2014 Journal Article Ubiquitylation and activation of a Rab GTPase is promoted by a beta(2)AR-HACE1 complexLachance, Veronik, Degrandmaison, Jade, Marois, Sebastien, Robitaille, Melanie, Genier, Samuel, Nadeau, Stephanie, Angers, Stephane and Parent, Jean-Luc (2014). Ubiquitylation and activation of a Rab GTPase is promoted by a beta(2)AR-HACE1 complex. Journal of Cell Science, 127 (1), 111-123. doi: 10.1242/jcs.132944 |
2013 Conference Publication Transcriptional regulation at IGF2 promoters and mechanistic insights on induction of IGF2 downstream of yap in SHH medulloblastomasDev, Abhinav, Robitaille, Melanie, Remke, Marc, Faury, Damien, Maier, Caroline, Malhotra, Anshu, Jabado, Nada, Taylor, Michael, Angers, Stephane and Kenney, Anna (2013). Transcriptional regulation at IGF2 promoters and mechanistic insights on induction of IGF2 downstream of yap in SHH medulloblastomas. 4th Quadrennial Meeting of the World-Federation-of-Neuro-Oncology (WFNO) held in conjunction with the 18th Annual Meeting of the Society-for-Neuro-Oncology (SNO), San Francisco, CA United States, 21-24 November 2013. Cary, NC United States: Oxford University Press. |
2013 Journal Article Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stabilityRoy, Sebastien J., Glazkova, Irina, Frechette, Louis, Iorio-Morin, Christian, Binda, Chantal, Petrin, Darlaine, Phan Trieu,, Robitaille, Melanie, Angers, Stephane, Hebert, Terence E. and Parent, Jean-Luc (2013). Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability. Molecular Endocrinology, 27 (8), 1245-1266. doi: 10.1210/me.2013-1091 |
2013 Conference Publication Characterization of a novel protein interactor of galphai suggests its involvement in mitotic spindle orientationChiu, Catherine, Robitaille, Melanie, Daulat, Avais, Zhao, Peishen, Chidiac, Peter, Obiero, Josiah and Angers, Stephane (2013). Characterization of a novel protein interactor of galphai suggests its involvement in mitotic spindle orientation. GPCR 2012, -, 2012. London, United Kingdom: Taylor & Francis. |