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2018 Conference Publication Rab27a promotes melanoma cell invasion and metastasis via the regulation of exosome secretionGuo, Dajiang, Lui, Goldie Y., Sharp, Danae M., Lai, Siew Li, Tikoo, Shweta, Kwan, Rain, van Geldermalsen, Michelle, Holst, Jeff, Haass, Nikolas K., Weninger, Wolfgang and Beaumont, Kimberley A. (2018). Rab27a promotes melanoma cell invasion and metastasis via the regulation of exosome secretion. Annual Meeting of the American-Association-for-Cancer-Research (AACR), Chicago Il, Apr 14-18, 2018. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2018-5167 |
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2018 Journal Article Endogenous replication stress marks melanomas sensitive to CHEK1 inhibitors in vivoOo, Zay Yar, Stevenson, Alexander J., Proctor, Martina A., Daignault, Sheena M., Walpole, Sebastian, Lanagan, Catherine, Chen, James, Skalamera, Dubravka, Spoerri, Loredana, Ainger, Stephen, Sturm, Richard A, Haass, Nikolas K and Gabrielli, Brian (2018). Endogenous replication stress marks melanomas sensitive to CHEK1 inhibitors in vivo. Clinical Cancer Research, 24 (12), 2901-2912. doi: 10.1158/1078-0432.CCR-17-2701 |
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2018 Journal Article Microenvironment-driven dynamic heterogeneity and phenotypic plasticity as a mechanism of melanoma therapy resistanceAhmed, Farzana and Haass, Nikolas K. (2018). Microenvironment-driven dynamic heterogeneity and phenotypic plasticity as a mechanism of melanoma therapy resistance. Frontiers in Oncology, 8 (May) 173, 1-7. doi: 10.3389/fonc.2018.00173 |
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2018 Journal Article HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanomaGallagher, Stuart J., Gunatilake, Dilini, Beaumont, Kimberley A., Sharp, Danae M., Tiffen, Jessamy C., Heinemann, Anja, Weninger, Wolfgang, Haass, Nikolas K., Wilmott, James S., Madore, Jason, Ferguson, Peter M., Rizos, Helen and Hersey, Peter (2018). HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma. International Journal of Cancer, 142 (9), 1926-1937. doi: 10.1002/ijc.31199 |
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2018 Conference Publication High Rab27a expression is associated with poor melanoma prognosis and promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomesGuo, D., Lui, G. Y., Tikoo, S., Weninger, W., Beaumont, K. A. and Haass, N. K. (2018). High Rab27a expression is associated with poor melanoma prognosis and promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes. International Investigative Dermatology (IID) Meeting, Orlando Fl, May 16-19, 2018. NEW YORK: ELSEVIER SCIENCE INC. |
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2018 Journal Article Mathematical models for cell migration with real-time cell cycle dynamicsVittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K and Simpson, Matthew J (2018). Mathematical models for cell migration with real-time cell cycle dynamics. Biophysical Journal, 114 (5), 1241-1253. doi: 10.1016/j.bpj.2017.12.041 |
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2018 Journal Article Acetylsalicylic acid governs the effect of sorafenib in RAS- mutant cancersHammerlindl, Heinz, Ravindran Menon, Dinoop, Hammerlindl, Sabrina, Emran, Abdullah Al, Torrano, Joachim, Sproesser, Katrin, Thakkar, Divya, Xiao, Min, Atkinson, Victoria G., Gabrielli, Brian, Haass, Nikolas K., Herlyn, Meenhard, Krepler, Clemens and Schaider, Helmut (2018). Acetylsalicylic acid governs the effect of sorafenib in RAS- mutant cancers. Clinical Cancer Research, 24 (5), 1090-1102. doi: 10.1158/1078-0432.CCR-16-2118 |
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2018 Conference Publication Escape form adaptive drug tolerance through OGT and TET1 mediated H3K4me3 remodeling in MAPKi-resistant melanomaMenon, D. Ravindran, Hammerlindl, H., Emran, A., Torrano, J., Hammerlindl, S., Zhang, G., Krause, L., Somasundaram, R., Sturm, R., Haass, N. K., Flaherty, K., Herlyn, M. and Schaider, H. (2018). Escape form adaptive drug tolerance through OGT and TET1 mediated H3K4me3 remodeling in MAPKi-resistant melanoma. International Investigative Dermatology (IID) Meeting, Orlando, Fl, United States, 16-19 May 2018. London, United Kingdom: Nature Publishing Group. doi: 10.1016/j.jid.2018.03.1252 |
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2018 Conference Publication Magnolol induces cell death through PI3K/Akt mediated epigenetic modifications boosting targeted inhibition in BRAF and NRAS mutant melanomaEmran, A., Chowdhury, B. R., Hammerlindl, H., Ahmed, F., Haass, N. K., Schuehly, W. and Schaider, H. (2018). Magnolol induces cell death through PI3K/Akt mediated epigenetic modifications boosting targeted inhibition in BRAF and NRAS mutant melanoma. Australasian College of Dermatologists, 51st Annual Scientific Meeting, Gold Coast, QLD, Australia, 19-22 May 2018. Hoboken, NJ, United States: Wiley. |
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2018 Conference Publication Escape form adaptive drug tolerance through OGT and TET1 mediated H3K4me3 remodeling in MAPKi resistant melanomaMenon, Dinoop Ravindran, Hammerlindl, Heinz, Al Emran, Abdullah, Torrano, Joachim, Hammerlindl, Sabrina, Zhang, Gao, Somasundaram, Rajasekharan, Sturm, Richard A., Haass, Nikolas K., Flaherty, Keith, Herlyn, Meenhard and Schaider, Helmut (2018). Escape form adaptive drug tolerance through OGT and TET1 mediated H3K4me3 remodeling in MAPKi resistant melanoma. Annual Meeting of the American Association for Cancer Research (AACR), Chicago, IL United States, 14-18 April 2018. Philadelphia, PA United States: American Association of Cancer Research. doi: 10.1158/1538-7445.AM2018-5833 |
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2018 Conference Publication Overexpression of the cell cycle regulator Emi1 promotes chromosome instability and tumorigenesisDuijf, Pascal H. G., Vaidyanathan, Srividya, Cato, Kathleen, Thangavelu, Pulari U., Lin, Cheng-Yu, Tang, Lu, Pavey, Sandra, Haass, Nikolas K. and Gabrielli, Brian G. (2018). Overexpression of the cell cycle regulator Emi1 promotes chromosome instability and tumorigenesis. 76th Annual Meeting of the Japanese Cancer Association, Yokohama, Japan, 28-30 September 2017. Tokyo, Japan: Wiley Japan. doi: 10.1111/cas.13499 |
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2018 Conference Publication Targeting cell cycle phase-specific drug sensitivity for melanoma therapyDaignault, S. M., Hill, D. S., Spoerri, L., Stehbens, S., Weninger, W., Gabrielli, B., Dolcetti, R. and Haass, N. K. (2018). Targeting cell cycle phase-specific drug sensitivity for melanoma therapy. 45th Annual Meeting of the Arbeitsgemeinscha-Dermatologische-Forschung (ADF), Zurich, Switzerland, 7-10 March 2018. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. |
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2018 Conference Publication Rab27a, a novel marker for melanoma metastasis and poor prognosisGuo, D., Lui, G. Y., Weninger, W., Beaumont, K. A. and Haass, N. K. (2018). Rab27a, a novel marker for melanoma metastasis and poor prognosis. Australasian College of Dermatologists, 51st Annual Scientific Meeting, Gold Coast, QLD, Australia, 19-22 May 2018. Hoboken, NJ, United States: Wiley. |
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2017 Conference Publication Microphthalmia-associated transcription factor regulates dynamic melanoma heterogeneityHaass, N. K., Spoerri, L., Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Jurek, R. J., Daignault, S. M., Ahmed, F., Smith, A. G. and Weninger, W. (2017). Microphthalmia-associated transcription factor regulates dynamic melanoma heterogeneity. 47th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR), Salzburg, Austria, 27-30 September 2017. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2017.07.726 |
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2017 Journal Article Dendritic mesoporous silica nanoparticles for pH-stimuli-responsive drug delivery of TNF-alphaKienzle, Arne, Kurch, Sven, Schloder, Janine, Berges, Carsten, Ose, Robert, Schupp, Jonathan, Tuettenberg, Andrea, Weiss, Henning, Schultze, Jennifer, Winzen, Svenja, Schinnerer, Meike, Koynov, Kaloian, Mezger, Markus, Haass, Nikolas K., Tremel, Wolfgang and Jonuleit, Helmut (2017). Dendritic mesoporous silica nanoparticles for pH-stimuli-responsive drug delivery of TNF-alpha. Advanced Healthcare Materials, 6 (13) 1700012, 1700012+. doi: 10.1002/adhm.201700012 |
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2017 Journal Article Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failureSmith, Michael P., Rowling, Emily J., Miskolczi, Zsofia, Ferguson, Jennifer, Spoerri, Loredana, Haass, Nikolas K., Sloss, Olivia, Mcentegart, Sophie, Arozarena, Imanol, von Kriegsheim, Alex, Rodriguez, Javier, Brunton, Holly, Kmarashev, Jivko, Levesque, Mitchell P., Dummer, Reinhard, Frederick, Dennie T., Andrews, Miles C., Cooper, Zachary A., Flaherty, Keith T., Wargo, Jennifer A. and Wellbrock, Claudia (2017). Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure. EMBO Molecular Medicine, 9 (8), 1011-1029. doi: 10.15252/emmm.201607156 |
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2017 Journal Article Cell cycle-tailored targeting of metastatic melanoma: challenges and opportunitiesHaass, Nikolas K. and Gabrielli, Brian (2017). Cell cycle-tailored targeting of metastatic melanoma: challenges and opportunities. Experimental Dermatology, 26 (7), 649-655. doi: 10.1111/exd.13303 |
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2017 Journal Article NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITFFane, Mitchell E., Chhabra, Yash, Hollingsworth, David E. J., Simmons, Jacinta L., Spoerri, Loredana, Oh, Tae Gyu, Chauhan, Jagat, Chin, Toby, Harris, Lachlan, Harvey, Tracey J., Muscat, George E. O., Goding, Colin R., Sturm, Richard A., Haass, Nikolas K., Boyle, Glen M., Piper, Michael and Smith, Aaron G. (2017). NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF. EBioMedicine, 16, 63-75. doi: 10.1016/j.ebiom.2017.01.013 |
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2017 Book Chapter Real-time cell cycle imaging in a 3D cell culture model of melanomaSpoerri, Loredana, Beaumont, Kimberley A., Anfosso, Andrea and Haass, Nikolas K. (2017). Real-time cell cycle imaging in a 3D cell culture model of melanoma. In 3D cell culture: methods and protocols (pp. 401-416) New York, NY, United States: Humana Press. doi:10.1007/978-1-4939-7021-6_29 |
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2017 Book Chapter Cell–cell contacts in melanoma and the tumor microenvironmentKuphal, Silke and Haass, Nikolas K. (2017). Cell–cell contacts in melanoma and the tumor microenvironment. Melanoma development: molecular biology, genetics and clinical application. (pp. 227-269) edited by Anja K. Bosserhoff. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-41319-8_9 |
