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2020

Journal Article

Examining go-or-grow using fluorescent cell-cycle indicators and cell-cycle-inhibiting drugs

Vittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2020). Examining go-or-grow using fluorescent cell-cycle indicators and cell-cycle-inhibiting drugs. Biophysical journal, 118 (6), 1243-1247. doi: 10.1016/j.bpj.2020.01.036

Examining go-or-grow using fluorescent cell-cycle indicators and cell-cycle-inhibiting drugs

2020

Conference Publication

Estimation of cell cycle states of human melanoma cells with quantitative phase imaging and deep learning

Henser-Brownhill, Tristan, Ju, Robert J., Haass, Nikolas K., Stehbens, Samantha J., Ballestrem, Christoph and Cootes, Timothy F. (2020). Estimation of cell cycle states of human melanoma cells with quantitative phase imaging and deep learning. 2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI), Iowa City, IA United States, 3-7 April 2020. Piscataway, NJ United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/isbi45749.2020.9098458

Estimation of cell cycle states of human melanoma cells with quantitative phase imaging and deep learning

2020

Conference Publication

MITF-mediated changes of tumor architecture, tensile stress and extracellular matrix control intratumor heterogeneity in melanoma

Spoerri, L., Tonnessen-Murray, Ca, Beaumont, K. A., Hill, D., Jurek, R., Gunasingh, G., Weninger, W. and Haass, N. K. (2020). MITF-mediated changes of tumor architecture, tensile stress and extracellular matrix control intratumor heterogeneity in melanoma. Virtual Conference of the Society for Investigative Dermatology (SID ), Online, 13-16 May 2020. New York, NY, United States: Elsevier.

MITF-mediated changes of tumor architecture, tensile stress and extracellular matrix control intratumor heterogeneity in melanoma

2019

Journal Article

Mathematical models incorporating a multi-stage cell cycle replicate normally-hidden inherent synchronization in cell proliferation

Vittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2019). Mathematical models incorporating a multi-stage cell cycle replicate normally-hidden inherent synchronization in cell proliferation. Journal of The Royal Society Interface, 16 (157) 20190382, 20190382. doi: 10.1098/rsif.2019.0382

Mathematical models incorporating a multi-stage cell cycle replicate normally-hidden inherent synchronization in cell proliferation

2019

Journal Article

Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine

Oo, Zay Yar, Proctor, Martina, Stevenson, Alexander J., Nazareth, Deborah, Fernando, Madushan, Daignault, Sheena M., Lanagan, Catherine, Walpole, Sebastian, Bonazzi, Vanessa, Škalamera, Dubravka, Snell, Cameron, Haass, Nikolas K., Larsen, Jill E. and Gabrielli, Brian (2019). Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine. Molecular Oncology, 13 (7) 1878-0261.12497, 1503-1518. doi: 10.1002/1878-0261.12497

Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine

2019

Journal Article

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes

Guo, Dajiang, Lui, Goldie Y. L., Lai, Siew Li, Wilmott, James S., Tikoo, Shweta, Jackett, Louise A., Quek, Camelia, Brown, Darren L., Sharp, Danae M., Kwan, Rain Y. Q., Chacon, Diego, Wong, Jason H., Beck, Dominik, van Geldermalsen, Michelle, Holst, Jeff, Thompson, John F., Mann, Graham J., Scolyer, Richard A., Stow, Jennifer L., Weninger, Wolfgang, Haass, Nikolas K. and Beaumont, Kimberley A. (2019). RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes. International Journal of Cancer, 144 (12), 3070-3085. doi: 10.1002/ijc.32064

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes

2019

Journal Article

RAB27A-mediated melanoma exosomes: promoters of invasion and metastasis

Guo, Dajiang, Tikoo, Shweta and Haass, Nikolas K. (2019). RAB27A-mediated melanoma exosomes: promoters of invasion and metastasis. Translational Cancer Research, 8 (3), 732-735. doi: 10.21037/tcr.2019.04.25

RAB27A-mediated melanoma exosomes: promoters of invasion and metastasis

2019

Journal Article

BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival

Lee, Erinna F., Harris, Tiffany J., Tran, Sharon, Evangelista, Marco, Arulananda, Surein, John, Thomas, Ramnac, Celeste, Hobbs, Chloe, Zhu, Haoran, Gunasingh, Gency, Segal, David, Behren, Andreas, Cebon, Jonathan, Dobrovic, Alexander, Mariadason, John M., Strasser, Andreas, Rohrbeck, Leona, Haass, Nikolas K., Herold, Marco J. and Fairlie, W. Douglas (2019). BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival. Cell Death & Disease, 10 (5) 342, 342. doi: 10.1038/s41419-019-1568-3

BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival

2019

Journal Article

Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma

Emran, Abdullah Al, Chinna Chowdary, Brinda Reddy, Ahmed, Farzana, Hammerlindl, Heinz, Huefner, Antje, Haass, Nikolas K., Schuehly, Wolfgang and Schaider, Helmut (2019). Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma. Cancer Medicine, 8 (3), 1186-1196. doi: 10.1002/cam4.1978

Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma

2019

Journal Article

Cover image

Emran, Abdullah Al, Chinna Chowdary, Brinda Reddy, Ahmed, Farzana, Hammerlindl, Heinz, Huefner, Antje, Haass, Nikolas K., Schuehly, Wolfgang and Schaider, Helmut (2019). Cover image. Cancer Medicine, 8 (3), i-i. doi: 10.1002/cam4.2129

Cover image

2019

Conference Publication

Bortezomib induces immunogenic cell death in melanoma and enhances immune responses in vivo

Daignault, S. M., Ju, R. J., Spoerri, L., Stehbens, S. J., Dolcetti, R. and Haass, N. K. (2019). Bortezomib induces immunogenic cell death in melanoma and enhances immune responses in vivo. 49th Annual Meeting of the European Society for Dermatological Research (ESDR), Bordeaux, France, 18-21 September, 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.506

Bortezomib induces immunogenic cell death in melanoma and enhances immune responses in vivo

2019

Conference Publication

Uncovering microtubule-driven mechanisms of melanoma invasion

Ju, R. J., Chhabra, Y., Haass, N. and Stehbens, S. J. (2019). Uncovering microtubule-driven mechanisms of melanoma invasion. 46th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Munich Germany, Mar 13-16, 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

Uncovering microtubule-driven mechanisms of melanoma invasion

2019

Conference Publication

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes

Guo, D., Lui, G. Y., Wilmott, J. S., Tikoo, S., Brown, D. L., Mann, G. J., Scolyer, R. A., Stow, J. L., Weninger, W., Beaumont, K. A. and Haass, N. (2019). RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes. 46th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Munich, GERMANY, MAR 13-16, 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes

2019

Conference Publication

Bortezomib-induced immunogenic cell death enhances immune response in melanoma

Daignault, S. M., Ju, R., Spoerri, L., Stehbens, S. J., Hill, D. S., Gabrielli, B., Dolcetti, R. and Haass, N. K. (2019). Bortezomib-induced immunogenic cell death enhances immune response in melanoma. Society for Investigative Dermatology (SID) Meeting, Chicago, IL United States, 8-11 May 2019. London, United Kingdom: Nature Publishing Group. doi: 10.1016/j.jid.2019.03.907

Bortezomib-induced immunogenic cell death enhances immune response in melanoma

2019

Conference Publication

Subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors for optimal tumor control and immune responses in vitro and in vivo

Oo, Zay Yar, Proctor, Martina, Stevenson, Alex, Nazareth, Deborah, Larsen, Jill, Haass, Nikolas and Gabrielli, Brian G. (2019). Subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors for optimal tumor control and immune responses in vitro and in vivo. AACR Annual Meeting on Bioinformatics, Convergence Science, and Systems Biology, Atlanta Ga, Mar 29-Apr 03, 2019. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2019-1236

Subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors for optimal tumor control and immune responses in vitro and in vivo

2019

Conference Publication

Microphthalmia-associated transcription factor regulates dynamic heterogeneity and structural integrity in melanoma

Spoerri, L., Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Jurek, R. J., Smith, A., Scott, E., Schaider, H., Gabrielli, B., Weninger, W. and Haass, N. (2019). Microphthalmia-associated transcription factor regulates dynamic heterogeneity and structural integrity in melanoma. 46th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Munich, Germany, 13-16 March, 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/exd.13859

Microphthalmia-associated transcription factor regulates dynamic heterogeneity and structural integrity in melanoma

2019

Conference Publication

MITF-mediated extracellular matrix changes control intratumour heterogeneity in melanoma

Spoerri, L., Tonnessen, C., Beaumont, K., Hill, D., Jurek, R., Gunasingh, G., Daignault, S. M., Vanwalleghem, G., Weninger, W., Scott, E. and Haass, N. K. (2019). MITF-mediated extracellular matrix changes control intratumour heterogeneity in melanoma. 49th Annual ESDR Meeting, Bordeaux, France, 18-21 September 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.709

MITF-mediated extracellular matrix changes control intratumour heterogeneity in melanoma

2019

Conference Publication

GGCX mutations in a patient with co-existent overlapping PXE/CL phenotype and thalassemia minor

Li, D., Ryu, E., Saeidian, A. H., Youssefian, L., Duvall, E., Oliphant, E., Terry, S., Haass, N. K., Uitto, J. and Li, Q. (2019). GGCX mutations in a patient with co-existent overlapping PXE/CL phenotype and thalassemia minor. Society for Investigative Dermatology (SID) Meeting, Chicago, IL United States, 8-11 May 2019. New York, NY United States: Elsevier.

GGCX mutations in a patient with co-existent overlapping PXE/CL phenotype and thalassemia minor

2019

Conference Publication

Enforcing cellular stress promotes apoptotic and immunogenic responses in melanoma

Daignault, S. M., Spoerri, L., Ju, R. J., Stehbens, S. J., Hill, D. S., Dolcetti, R. and Haass, N. (2019). Enforcing cellular stress promotes apoptotic and immunogenic responses in melanoma. 46th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Munich, Germany, 13-16 March 2019. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1111/exd.13859

Enforcing cellular stress promotes apoptotic and immunogenic responses in melanoma

2018

Journal Article

Stochastic models of cell invasion with fluorescent cell cycle indicators

Simpson, Matthew J., Jin, Wang, Vittadello, Sean T., Tambyah, Tamara A., Ryan, Jacob M., Gunasingh, Gency, Haass, Nikolas K. and McCue, Scott W. (2018). Stochastic models of cell invasion with fluorescent cell cycle indicators. Physica A: Statistical Mechanics and its Applications, 510, 375-386. doi: 10.1016/j.physa.2018.06.128

Stochastic models of cell invasion with fluorescent cell cycle indicators