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2019 Journal Article Mathematical models incorporating a multi-stage cell cycle replicate normally-hidden inherent synchronization in cell proliferationVittadello, Sean T., McCue, Scott W., Gunasingh, Gency, Haass, Nikolas K. and Simpson, Matthew J. (2019). Mathematical models incorporating a multi-stage cell cycle replicate normally-hidden inherent synchronization in cell proliferation. Journal of The Royal Society Interface, 16 (157) 20190382, 20190382. doi: 10.1098/rsif.2019.0382 |
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2019 Journal Article Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabineOo, Zay Yar, Proctor, Martina, Stevenson, Alexander J., Nazareth, Deborah, Fernando, Madushan, Daignault, Sheena M., Lanagan, Catherine, Walpole, Sebastian, Bonazzi, Vanessa, Škalamera, Dubravka, Snell, Cameron, Haass, Nikolas K., Larsen, Jill E. and Gabrielli, Brian (2019). Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine. Molecular Oncology, 13 (7) 1878-0261.12497, 1503-1518. doi: 10.1002/1878-0261.12497 |
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2019 Journal Article RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomesGuo, Dajiang, Lui, Goldie Y. L., Lai, Siew Li, Wilmott, James S., Tikoo, Shweta, Jackett, Louise A., Quek, Camelia, Brown, Darren L., Sharp, Danae M., Kwan, Rain Y. Q., Chacon, Diego, Wong, Jason H., Beck, Dominik, van Geldermalsen, Michelle, Holst, Jeff, Thompson, John F., Mann, Graham J., Scolyer, Richard A., Stow, Jennifer L., Weninger, Wolfgang, Haass, Nikolas K. and Beaumont, Kimberley A. (2019). RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes. International Journal of Cancer, 144 (12), 3070-3085. doi: 10.1002/ijc.32064 |
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2019 Journal Article RAB27A-mediated melanoma exosomes: promoters of invasion and metastasisGuo, Dajiang, Tikoo, Shweta and Haass, Nikolas K. (2019). RAB27A-mediated melanoma exosomes: promoters of invasion and metastasis. Translational Cancer Research, 8 (3), 732-735. doi: 10.21037/tcr.2019.04.25 |
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2019 Journal Article BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survivalLee, Erinna F., Harris, Tiffany J., Tran, Sharon, Evangelista, Marco, Arulananda, Surein, John, Thomas, Ramnac, Celeste, Hobbs, Chloe, Zhu, Haoran, Gunasingh, Gency, Segal, David, Behren, Andreas, Cebon, Jonathan, Dobrovic, Alexander, Mariadason, John M., Strasser, Andreas, Rohrbeck, Leona, Haass, Nikolas K., Herold, Marco J. and Fairlie, W. Douglas (2019). BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival. Cell Death & Disease, 10 (5) 342, 342. doi: 10.1038/s41419-019-1568-3 |
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2019 Journal Article Cover imageEmran, Abdullah Al, Chinna Chowdary, Brinda Reddy, Ahmed, Farzana, Hammerlindl, Heinz, Huefner, Antje, Haass, Nikolas K., Schuehly, Wolfgang and Schaider, Helmut (2019). Cover image. Cancer Medicine, 8 (3), i-i. doi: 10.1002/cam4.2129 |
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2019 Journal Article Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanomaEmran, Abdullah Al, Chinna Chowdary, Brinda Reddy, Ahmed, Farzana, Hammerlindl, Heinz, Huefner, Antje, Haass, Nikolas K., Schuehly, Wolfgang and Schaider, Helmut (2019). Magnolol induces cell death through PI3K/Akt-mediated epigenetic modifications boosting treatment of BRAF- and NRAS-mutant melanoma. Cancer Medicine, 8 (3), 1186-1196. doi: 10.1002/cam4.1978 |
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2019 Conference Publication Uncovering microtubule-driven mechanisms of melanoma invasionJu, R. J., Chhabra, Y., Haass, N. and Stehbens, S. J. (2019). Uncovering microtubule-driven mechanisms of melanoma invasion. 46th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Munich Germany, Mar 13-16, 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. |
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2019 Conference Publication RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomesGuo, D., Lui, G. Y., Wilmott, J. S., Tikoo, S., Brown, D. L., Mann, G. J., Scolyer, R. A., Stow, J. L., Weninger, W., Beaumont, K. A. and Haass, N. (2019). RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes. 46th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Munich, GERMANY, MAR 13-16, 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. |
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2019 Conference Publication Bortezomib-induced immunogenic cell death enhances immune response in melanomaDaignault, S. M., Ju, R., Spoerri, L., Stehbens, S. J., Hill, D. S., Gabrielli, B., Dolcetti, R. and Haass, N. K. (2019). Bortezomib-induced immunogenic cell death enhances immune response in melanoma. Society for Investigative Dermatology (SID) Meeting, Chicago, IL United States, 8-11 May 2019. London, United Kingdom: Nature Publishing Group. doi: 10.1016/j.jid.2019.03.907 |
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2019 Conference Publication Subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors for optimal tumor control and immune responses in vitro and in vivoOo, Zay Yar, Proctor, Martina, Stevenson, Alex, Nazareth, Deborah, Larsen, Jill, Haass, Nikolas and Gabrielli, Brian G. (2019). Subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors for optimal tumor control and immune responses in vitro and in vivo. AACR Annual Meeting on Bioinformatics, Convergence Science, and Systems Biology, Atlanta Ga, Mar 29-Apr 03, 2019. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2019-1236 |
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2019 Conference Publication Microphthalmia-associated transcription factor regulates dynamic heterogeneity and structural integrity in melanomaSpoerri, L., Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Jurek, R. J., Smith, A., Scott, E., Schaider, H., Gabrielli, B., Weninger, W. and Haass, N. (2019). Microphthalmia-associated transcription factor regulates dynamic heterogeneity and structural integrity in melanoma. 46th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Munich, Germany, 13-16 March, 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/exd.13859 |
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2019 Conference Publication MITF-mediated extracellular matrix changes control intratumour heterogeneity in melanomaSpoerri, L., Tonnessen, C., Beaumont, K., Hill, D., Jurek, R., Gunasingh, G., Daignault, S. M., Vanwalleghem, G., Weninger, W., Scott, E. and Haass, N. K. (2019). MITF-mediated extracellular matrix changes control intratumour heterogeneity in melanoma. 49th Annual ESDR Meeting, Bordeaux, France, 18-21 September 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.709 |
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2019 Conference Publication GGCX mutations in a patient with co-existent overlapping PXE/CL phenotype and thalassemia minorLi, D., Ryu, E., Saeidian, A. H., Youssefian, L., Duvall, E., Oliphant, E., Terry, S., Haass, N. K., Uitto, J. and Li, Q. (2019). GGCX mutations in a patient with co-existent overlapping PXE/CL phenotype and thalassemia minor. Society for Investigative Dermatology (SID) Meeting, Chicago, IL United States, 8-11 May 2019. New York, NY United States: Elsevier. |
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2019 Conference Publication Enforcing cellular stress promotes apoptotic and immunogenic responses in melanomaDaignault, S. M., Spoerri, L., Ju, R. J., Stehbens, S. J., Hill, D. S., Dolcetti, R. and Haass, N. (2019). Enforcing cellular stress promotes apoptotic and immunogenic responses in melanoma. 46th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF), Munich, Germany, 13-16 March 2019. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1111/exd.13859 |
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2019 Conference Publication Bortezomib induces immunogenic cell death in melanoma and enhances immune responses in vivoDaignault, S. M., Ju, R. J., Spoerri, L., Stehbens, S. J., Dolcetti, R. and Haass, N. K. (2019). Bortezomib induces immunogenic cell death in melanoma and enhances immune responses in vivo. 49th Annual Meeting of the European Society for Dermatological Research (ESDR), Bordeaux, France, 18-21 September, 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.506 |
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2018 Journal Article Stochastic models of cell invasion with fluorescent cell cycle indicatorsSimpson, Matthew J., Jin, Wang, Vittadello, Sean T., Tambyah, Tamara A., Ryan, Jacob M., Gunasingh, Gency, Haass, Nikolas K. and McCue, Scott W. (2018). Stochastic models of cell invasion with fluorescent cell cycle indicators. Physica A: Statistical Mechanics and its Applications, 510, 375-386. doi: 10.1016/j.physa.2018.06.128 |
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2018 Journal Article The role of melanoma cell-stroma interaction in cell motility, invasion, and metastasisJu, Robert J., Stehbens, Samantha J. and Haass, Nikolas K. (2018). The role of melanoma cell-stroma interaction in cell motility, invasion, and metastasis. Frontiers in Medicine, 5 (NOV) 307, 1-9. doi: 10.3389/fmed.2018.00307 |
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2018 Conference Publication Less is more: subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors in vitro and in vivoOo, Z. U., Proctor, M., Stevenson, A., Nazareth, D., Haass, N., Larsen, J. and Gabrielli, B. (2018). Less is more: subclinical doses and choice of replication stress inducer in combination with CHK1 inhibitors in vitro and in vivo. 30th EORTC-NCI-AACR Symposium, Dublin Ireland, Nov 13-16, 2018. OXFORD: ELSEVIER SCI LTD. |
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2018 Journal Article FGFR2b activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancerStehbens, Samantha J., Ju, Robert J., Adams, Mark N., Perry, Samuel, Haass, Nikolas K., Bryant, David M. and Pollock, Pamela M. (2018). FGFR2b activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer. Journal of Cell Science, 131 (15) jcs.213678, 1-16. doi: 10.1242/jcs.213678 |
