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2015

Journal Article

Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS

Ke, Yazi D., van Hummel, Annika, Stevens, Claire H., Gladbach, Amadeus, Ippati, Stefania, Bi, Mian, Lee, Wei S., Kruger, Sarah, van der Hoven, Julia, Volkerling, Alexander, Bongers, Andre, Halliday, Glenda, Haass, Nikolas K., Kiernan, Matthew, Delerue, Fabien and Ittner, Lars M. (2015). Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS. Acta Neuropathologica, 130 (5), 661-678. doi: 10.1007/s00401-015-1486-0

Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS

2015

Journal Article

Corrigendum: a stress-induced early innate response causes multidrug tolerance in melanoma (vol 34, pg 4448, 2015)

Menon, D. Ravindran, Das, S., Krepler, C., Vultur, A., Rinner, B., Schauer, S., Kashofer, K., Wagner, K., Zhang, G., Rad, E. Bonyadi, Haass, N. K., Soyer, H. P., Gabrielli, B., Somasundaram, R., Hoefler, G., Herlyn, M. and Schaider, H. (2015). Corrigendum: a stress-induced early innate response causes multidrug tolerance in melanoma (vol 34, pg 4448, 2015). Oncogene, 34 (34), 4545-4545. doi: 10.1038/onc.2014.432

Corrigendum: a stress-induced early innate response causes multidrug tolerance in melanoma (vol 34, pg 4448, 2015)

2015

Journal Article

A stress-induced early innate response causes multidrug tolerance in melanoma

Ravindran Menon, D., Das, S., Krepler, C., Vultur, A., Rinner, B., Schauer, S., Kashofer, K., Wagner, K., Zhang, G., Bonyadi Rad, E., Haass, N. K., Soyer, H. P., Gabrielli, B., Somasundaram, R., Hoefler, G., Herlyn, M. and Schaider, H. (2015). A stress-induced early innate response causes multidrug tolerance in melanoma. Oncogene, 34 (34), 4448-4459. doi: 10.1038/onc.2014.372

A stress-induced early innate response causes multidrug tolerance in melanoma

2015

Conference Publication

MITF regulates proliferative subpopulation tumor architecture and modifies invasion and characteristics of the epithelial to mesenchymal transition within melanoma

Tonnessen, Crystal A., Beaumont, Kimberley A., Hill, David S., Daignault, Sheena M., Anfosso, Andrea, Jurek, Russell J., Weninger, Wolfgang and Haass, Nikolas K. (2015). MITF regulates proliferative subpopulation tumor architecture and modifies invasion and characteristics of the epithelial to mesenchymal transition within melanoma. 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, United States, 18-22 April 2015. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2015-1420

MITF regulates proliferative subpopulation tumor architecture and modifies invasion and characteristics of the epithelial to mesenchymal transition within melanoma

2015

Journal Article

Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system?

Haass, Nikolas K. (2015). Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system?. Melanoma Management, 2 (2), 93-95. doi: 10.2217/MMT.15.1

Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system?

2015

Journal Article

Friends or foes: IL-10 and TGF-beta in melanoma

Tikoo, Shweta and Haass, Nikolas K. (2015). Friends or foes: IL-10 and TGF-beta in melanoma. Experimental Dermatology, 24 (4), 254-255. doi: 10.1111/exd.12661

Friends or foes: IL-10 and TGF-beta in melanoma

2015

Journal Article

Expression of Bcl-xL and Mcl-1 in the Nonmelanoma Skin Cancers of Renal Transplant Recipients

Burke, Michael T., Morais, Christudas, Oliver, Kimberley A., Lambie, Duncan L. J., Gobe, Glenda C., Carroll, Robert P., Staatz, Christine E., Sinnya, Sudipta, Soyer, H. Peter, Winterford, Clay, Haass, Nikolas K., Campbell, Scott B. and Isbel, Nicole M. (2015). Expression of Bcl-xL and Mcl-1 in the Nonmelanoma Skin Cancers of Renal Transplant Recipients. American Journal of Clinical Pathology, 143 (4), 514-526. doi: 10.1309/AJCPQNB5WA3PLQBK

Expression of Bcl-xL and Mcl-1 in the Nonmelanoma Skin Cancers of Renal Transplant Recipients

2015

Conference Publication

Targeting Rab27a to suppress melanoma proliferation and invasion

Beaumont, K. A., Sharp, D. M., Weninger, W. and Haass, N. K. (2015). Targeting Rab27a to suppress melanoma proliferation and invasion. 42nd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Ulm, Germany, 05-07 March 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/exd.12623

Targeting Rab27a to suppress melanoma proliferation and invasion

2015

Book Chapter

Cell cycle checkpoint and DNA damage response defects as anticancer targets: from molecular mechanisms to therapeutic opportunities.

Spoerri, Loredana, Oo, Zay Yar, Larsen, Jill E., Haass, Nikolas K., Gabrielli, Brian and Pavey, Sandra (2015). Cell cycle checkpoint and DNA damage response defects as anticancer targets: from molecular mechanisms to therapeutic opportunities.. Stress response pathways in cancer: from molecular targets to novel therapeutics. (pp. 29-49) edited by Georg T. Wondrak. Dordrecht: Springer Science+Business Media. doi: 10.1007/978-94-017-9421-3_3

Cell cycle checkpoint and DNA damage response defects as anticancer targets: from molecular mechanisms to therapeutic opportunities.

2015

Journal Article

Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.

Haass, Nikolas K., Nassif, Najah and McGowan, Eileen M. (2015). Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.. BioMed Research International, 2015 165105, 165105.1-165105.9. doi: 10.1155/2015/165105

Switching the sphingolipid rheostat in the treatment of diabetes and cancer comorbidity from a problem to an advantage.

2015

Conference Publication

Melanoma tumor sub-populations are defined by MITF expression, and exhibit enhanced proliferation and characteristics of an EMT

Tonnessen, C. A., Beaumont, K. A., Hill, D. S., Anfosso, A., Daignault, S. M., Fane, M., Jurek, R. J., Smith, A. G., Weninger, W. and Haass, N. K. (2015). Melanoma tumor sub-populations are defined by MITF expression, and exhibit enhanced proliferation and characteristics of an EMT. 42nd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Ulm, Germany, 05-07 March 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/exd.12623

Melanoma tumor sub-populations are defined by MITF expression, and exhibit enhanced proliferation and characteristics of an EMT

2015

Conference Publication

Making stressed melanoma self-destruct

Hill, D. S., Beaumont, K. A., Daignault, S. M., Anfosso, A., Lovat, P. E., Weninger, W. and Haass, N. K. (2015). Making stressed melanoma self-destruct. Australasian College of Dermatologists 48th Annual Scientific Meeting, Adelaide, Australia, 16 May, 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12337

Making stressed melanoma self-destruct

2015

Conference Publication

An early innate stress response precedes acquired drug resistance in melanoma

Menon, Dinoop Ravindran, Das, Suman, Krepler, Clemens, Vultur, Adina, Zhang, Gao, Haass, Nikolas, Soyer, Peter H., Gabrielli, Brian, Somasundaram, Rajasekharan, Hoefler, Gerald, Herlyn, Meenhard and Schaider, Helmut (2015). An early innate stress response precedes acquired drug resistance in melanoma. 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia Pa United States, April 18-22, 2015. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2015-2684

An early innate stress response precedes acquired drug resistance in melanoma

2015

Conference Publication

Melanoma cells in G1 phase escape proteasome inhibitor cytotoxicity

Hill, D. S., Beaumont, K. A., Daignault, S. M., Anfosso, A., Sharp, D. M., Gabrielli, B., Lovat, P. E., Weninger, W. and Haass, N. K. (2015). Melanoma cells in G1 phase escape proteasome inhibitor cytotoxicity. 42nd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Ulm, Germany, Mar 05-07, 2015. Chichester, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/exd.12623

Melanoma cells in G1 phase escape proteasome inhibitor cytotoxicity

2015

Book Chapter

Melanoma: From tumor-specific mutations to a new molecular taxonomy and innovative therapeutics

Tonnessen, Crystal A. and Haass, Nikolas K. (2015). Melanoma: From tumor-specific mutations to a new molecular taxonomy and innovative therapeutics. Personalized treatment options in dermatology. (pp. 7-27) edited by Thomas Bieber and Frank Nestle. Heidelberg, Germany: Springer. doi: 10.1007/978-3-662-45840-2_2

Melanoma: From tumor-specific mutations to a new molecular taxonomy and innovative therapeutics

2014

Journal Article

Induction of endoplasmic reticulum stress as a strategy for melanoma therapy: is there a future?

Hill, David S., Lovat, Penny E. and Haass, Nikolas K. (2014). Induction of endoplasmic reticulum stress as a strategy for melanoma therapy: is there a future?. Melanoma Management, 1 (2), 127-137. doi: 10.2217/MMT.14.16

Induction of endoplasmic reticulum stress as a strategy for melanoma therapy: is there a future?

2014

Journal Article

Targeting glutamine transport to suppress melanoma cell growth

Wang, Qian, Beaumont, Kimberley A., Otte, Nicholas J., Font, Josep, Bailey, Charles G., van Geldermalsen, Michelle, Sharp, Danae M., Tiffen, Jessamy C., Ryan, Renae M., Jormakka, Mika, Haass, Nikolas K., Rasko, John E. J. and Holst, Jeff (2014). Targeting glutamine transport to suppress melanoma cell growth. International Journal of Cancer, 135 (5), 1060-1071. doi: 10.1002/ijc.28749

Targeting glutamine transport to suppress melanoma cell growth

2014

Journal Article

Real-time cell cycle imaging during melanoma growth, invasion, and drug response

Haass, Nikolas K., Beaumont, Kimberley A., Hill, David S., Anfosso, Andrea, Mrass, Paulus, Munoz, Marcia A., Kinjyo, Ichiko and Weninger, Wolfgang (2014). Real-time cell cycle imaging during melanoma growth, invasion, and drug response. Pigment Cell and Melanoma Research, 27 (5), 764-776. doi: 10.1111/pcmr.12274

Real-time cell cycle imaging during melanoma growth, invasion, and drug response

2014

Journal Article

Detection of primary melanoma in individuals at extreme high risk: a prospective 5-year follow-up study

Moloney, Fergal J., Guitera, Pascale, Coates, Elliot, Haass, Nikolas K., Ho, Kenneth, Khoury, Ritta, O'Connell, Rachel L., Raudonikis, Leo, Schmid, Helen, Mann, Graham J. and Menzies, Scott W. (2014). Detection of primary melanoma in individuals at extreme high risk: a prospective 5-year follow-up study. JAMA Dermatology, 150 (8), 819-827. doi: 10.1001/jamadermatol.2014.514

Detection of primary melanoma in individuals at extreme high risk: a prospective 5-year follow-up study

2014

Journal Article

Melanoma never says die

Haass, Nikolas K. and Schumacher, Udo (2014). Melanoma never says die. Experimental Dermatology, 23 (7), 471-472. doi: 10.1111/exd.12400

Melanoma never says die