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2015 Journal Article C9orf72 hexanucleotide repeat expansions in Chinese sporadic amyotrophic lateral sclerosisHe, Ji, Tang, Lu, Benyamin, Beben, Shah, Sonia, Hemani, Gib, Liu, Rong, Ye, Shan, Liu, Xiaolu, Ma, Yan, Zhang, Huagang, Cremin, Katie, Leo, Paul, Wray, Naomi R., Visscher, Peter M., Xu, Huji, Brown, Matthew A., Bartlett, Perry F., Mangelsdorf, Marie and Fan, Dongsheng (2015). C9orf72 hexanucleotide repeat expansions in Chinese sporadic amyotrophic lateral sclerosis. Neurobiology of Aging, 36 (9) 2660.e1, 2660.e1-2660.e8. doi: 10.1016/j.neurobiolaging.2015.06.002 |
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2015 Journal Article Mendelian randomization of blood lipids for coronary heart diseaseHolmes, Michael V., Asselbergs, Folkert W., Palmer, Tom M., Drenos, Fotios, Lanktree, Matthew B., Nelson, Christopher P., Dale, Caroline E., Padmanabhan, Sandosh, Finan, Chris, Swerdlow, Daniel I., Tragante, Vinicius, van Iperen, Erik P. A., Sivapalaratnam, Suthesh, Shah, Sonia, Elbers, Clara C., Shah, Tina, Engmann, Jorgen, Giambartolomei, Claudia, White, Jon, Zabaneh, Delilah, Sofat, Reecha, McLachlan, Stela, Doevendans, Pieter A., Balmforth, Anthony J., Hall, Alistair S., North, Kari E., Almoguera, Berta, Hoogeveen, Ron C., Cushman, Mary ... Casas, Juan P. (2015). Mendelian randomization of blood lipids for coronary heart disease. European Heart Journal, 36 (9), 539-550. doi: 10.1093/eurheartj/eht571 |
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2015 Journal Article New genetic loci link adipose and insulin biology to body fat distributionShungin, Dmitry, Winkler, Thomas W, Croteau-Chonka, Damien C, Ferreira, Teresa, Locke, Adam E, Magi, Reedik, Strawbridge, Rona J, Pers, Tune H, Fischer, Krista, Justice, Anne E, Workalemahu, Tsegaselassie, Wu, Joseph M.W, Buchkovich, Martin L, Heard-Costa, Nancy L, Roman, Tamara S, Drong, Alexander W, Song, Ci, Gustafsson, Stefan, Day, Felix R, Esko, Tonu, Fall, Tove, Kutalik, Zoltan, Luan, Jian'an, Randall, Joshua C, Scherag, Andre, Vedantam, Sailaja, Wood, Andrew R, Chen, Jin, Fehrmann, Rudolf ... Shah, Sonia (2015). New genetic loci link adipose and insulin biology to body fat distribution. Nature, 518 (7538), 187-196. doi: 10.1038/nature14132 |
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2015 Journal Article Genetic studies of body mass index yield new insights for obesity biologyLocke, Adam E., Kahali, Bratati, Berndt, Sonja I., Justice, Anne E., Pers, Tune H., Day, Felix R., Powell, Corey, Vedantam, Sailaja, Buchkovich, Martin L., Yang, Jian, Croteau-Chonka, Damien C., Esko, Tonu, Fall, Tove, Ferreira, Teresa, Gustafsson, Stefan, Kutalik, Zoltán, Luan, Jian'an, Mägi, Reedik, Randall, Joshua C., Winkler, Thomas W., Wood, Andrew R., Workalemahu, Tsegaselassie, Faul, Jessica D., Smith, Jennifer A., Zhao, Jing Hua, Zhao, Wei, Chen, Jin, Fehrmann, Rudolf, Hedman, Asa K. ... Shah, Sonia (2015). Genetic studies of body mass index yield new insights for obesity biology. Nature, 518 (7538), 197-206. doi: 10.1038/nature14177 |
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2015 Journal Article DNA methylation age of blood predicts all-cause mortality in later lifeMarioni, Riccardo E., Shah, Sonia, McRae, Allan F., Chen, Brian H., Colicino, Elena, Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Murphy, Lee, Martin, Nicholas G., Montgomery, Grant W., Feinberg, Andrew P., Fallin, M. Daniele, Multhaup, Michael L., Jaffe, Andrew E., Joehanes, Roby, Schwartz, Joel, Just, Allan C., Lunetta, Kathryn L., Murabito, Joanne M., Starr, John M., Horvath, Steve, Baccarelli, Andrea A., Levy, Daniel, Visscher, Peter M. ... Deary, Ian J. (2015). DNA methylation age of blood predicts all-cause mortality in later life. Genome Biology, 16 (1) 25, 25.1-25.12. doi: 10.1186/s13059-015-0584-6 |
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2014 Journal Article Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traitsHerder, Christian, Nuotio, Marja-Liisa, Shah, Sonia, Blankenberg, Stefan, Brunner, Eric J., Carstensen, Maren, Gieger, Christian, Grallert, Harald, Jula, Antti, Kahonen, Mika, Kettunen, Johannes, Kivimaki, Mika, Koenig, Wolfgang, Kristiansson, Kati, Langenberg, Claudia, Lehtimaki, Terho, Luotola, Kari, Marzi, Carola, Mueller, Christian, Peters, Annette, Prokisch, Holger, Raitakari, Olli, Rathmann, Wolfgang, Roden, Michael, Salmi, Marko, Schramm, Katharina, Swerdlow, Daniel, Tabak, Adam G., Thorand, Barbara ... Salomaa, Veikko (2014). Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits. Diabetes, 63 (12), 4343-4359. doi: 10.2337/db14-0731 |
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2014 Journal Article Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis of the Polygenic Form of Clinical Familial Hypercholesterolemia and Replication in Samples from 6 CountriesFutema, Marta, Shah, Sonia, Cooper, Jackie A., Li, KahWa, Whittall, Ros A., Sharifi, Mahtab, Goldberg, Olivia, Drogari, Euridiki, Mollaki, Vasilik, Wiegman, Albert, Defesche, Joep, D'Agostino, Maria N., D'Angelo, Antonietta, Rubba, Paolo, Fortunato, Giuliana, Walus-Miarka, Malgorzata, Hegele, Robert A., Aderayo Bamimore, Mary, Durst, Ronen, Leitersdorf, Eran, Mulder, Monique T., Roeters van Lennep, Jeanine E., Sijbrands, Eric J., Whittaker, John C., Talmud, Philippa J. and Humphries, Steve E. (2014). Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis of the Polygenic Form of Clinical Familial Hypercholesterolemia and Replication in Samples from 6 Countries. Clinical Chemistry, 61 (1), 231-238. doi: 10.1373/clinchem.2014.231365 |
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2014 Journal Article Genetic and environmental exposures constrain epigenetic drift over the human life courseShah, Sonia, McRae, Allan F., Marioni, Riccardo E., Harris, Sarah E., Gibson, Jude, Henders, Anjali K., Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Murphy, Lee, Martin, Nicholas G., Montgomery, Grant W., Starr, John M., Wray, Naomi R., Deary, Ian J. and Visscher, Peter M. (2014). Genetic and environmental exposures constrain epigenetic drift over the human life course. Genome Research, 24 (11), 1725-1733. doi: 10.1101/gr.176933.114 |
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2014 Journal Article Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in menGigante, Bruna, Leander, Karin, Vikström, Max, Baldassarre, Damiano, Veglia, Fabrizio, Strawbridge, Rona J., McLeod, Olga, Gertow, Karl, Sennblad, Bengt, Shah, Sonia, Zabaneh, Delilah, Humphries, Steve E., Kauhanen, Jussi, Rauramaa, Rainer, Smit, Andries J., Mannarino, Elmo, Giral, Philippe, Tremoli, Elena, Hamsten, Anders, Frostegård, Johan and de Faire, Ulf (2014). Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men. Atherosclerosis, 236 (2), 394-399. doi: 10.1016/j.atherosclerosis.2014.07.030 |
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2014 Journal Article Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant dataHolmes, Michael V., Dale, Caroline E., Zuccolo, Luisa, Silverwood, Richard J., Guo, Yiran, Ye, Zheng, Prieto-Merino, David, Dehghan, Abbas, Trompet, Stella, Wong, Andrew, Cavadino, Alana, Drogan, Dagmar, Padmanabhan, Sandosh, Li, Shanshan, Yesupriya, Ajay, Leusink, Maarten, Sundstrom, Johan, Hubacek, Jaroslav A., Pikhart, Hynek, Swerdlow, Daniel I., Panayiotou, Andrie G., Borinskaya, Svetlana A., Finan, Chris, Shah, Sonia, Kuchenbaecker, Karoline B., Shah, Tina, Engmann, Jorgen, Folkersen, Lasse, Eriksson, Per ... Casas, Juan P. (2014). Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ - British Medical Journal, 349 (jul10 6) g4164, g4164-g4164. doi: 10.1136/bmj.g4164 |
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2014 Journal Article Contribution of genetic variation to transgenerational inheritance of DNA methylationMcRae, Allan F., Powell, Joseph E., Henders, Anjali K., Bowdler, Lisa, Hemani, Gibran, Shah, Sonia, Painter, Jodie N., Martin, Nicholas G., Visscher, Peter M. and Montgomery, Grant W. (2014). Contribution of genetic variation to transgenerational inheritance of DNA methylation. Genome Biology, 15 (5) R73, 1-10. doi: 10.1186/gb-2014-15-5-r73 |
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2014 Journal Article Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibilityDIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium, Shah, Sonia and Yengo, Loic (2014). Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics, 46 (3), 234-246. doi: 10.1038/ng.2897 |
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2014 Journal Article Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related lociTragante, Vinicius, Barnes, Michael R., Ganesh, Santhi K., Lanktree, Matthew B., Guo, Wei, Franceschini, Nora, Smith, Erin N., Johnson, Toby, Holmes, Michael V., Padmanabhan, Sandosh, Karczewski, Konrad J., Almoguera, Berta, Barnard, John, Baumert, Jens, Chang, Yen-Pei Christy, Elbers, Clara C., Farrall, Martin, Fischer, Mary E., Gaunt, Tom R., Gho, Johannes M. I. H., Gieger, Christian, Goel, Anuj, Gong, Yan, Isaacs, Aaron, Kleber, Marcus E., Leach, Irene Mateo, McDonough, Caitrin W., Meijs, Matthijs F. L., Melander, Olle ... Keating, Brendan J. (2014). Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. American Journal of Human Genetics, 94 (3), 349-360. doi: 10.1016/j.ajhg.2013.12.016 |
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2013 Journal Article Discovery and refinement of loci associated with lipid levelsWiller C.J., Schmidt E.M., Sengupta S., Peloso G.M., Gustafsson S., Kanoni S., Ganna A., Chen J., Buchkovich M.L., Mora S., Beckmann J.S., Bragg-Gresham J.L., Chang H.-Y., Demirkan A., Den Hertog H.M., Do R., Donnelly L.A., Ehret G.B., Esko T., Feitosa M.F., Ferreira T., Fischer K., Fontanillas P., Fraser R.M., Freitag D.F., Gurdasani D., Heikkila K., Hypponen E., Isaacs A. ... Abecasis G.R. (2013). Discovery and refinement of loci associated with lipid levels. Nature Genetics, 45 (11), 1274-1285. doi: 10.1038/ng.2797 |
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2013 Journal Article Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChipGaunt T.R., Zabaneh D., Shah S., Guyatt A., Ladroue C., Kumari M., Drenos F., Shah T., Talmud P.J., Casas J.P., Lowe G., Rumley A., Lawlor D.A., Kivimaki M., Whittaker J., Hingorani A.D., Humphries S.E. and Day I.N. (2013). Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip. Thrombosis and Haemostasis, 110 (5), 995-1003. doi: 10.1160/TH13-02-0087 |
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2013 Journal Article Common variants associated with plasma triglycerides and risk for coronary artery diseaseDo, Ron, Willer, Cristen J., Schmidt, Ellen M., Sengupta, Sebanti, Gao, Chi, Peloso, Gina M., Gustafsson, Stefan, Kanoni, Stavroula, Ganna, Andrea, Chen, Jin, Buchkovich, Martin L., Mora, Samia, Beckmann, Jacques S., Bragg-Gresham, Jennifer L., Chang, Hsing-Yi, Demirkan, Ayse, Den Hertog, Heleen M., Donnelly, Louise A., Ehret, Georg B., Esko, Tonu, Feitosa, Mary F., Ferreira, Teresa, Fischer, Krista, Fontanillas, Pierre, Fraser, Ross M., Freitag, Daniel F., Gurdasani, Deepti, Heikkila, Kauko, Hyppoenen, Elina ... Kathiresan, Sekar (2013). Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics, 45 (11), 1345-1352. doi: 10.1038/ng.2795 |
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2013 Journal Article Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) ConsortiumShah, Tina, Engmann, Jorgen, Dale, Caroline, Shah, Sonia, White, Jon, Giambartolomei, Claudia, McLachlan, Stela, Zabaneh, Delilah, Cavadino, Alana, Finan, Chris, Wong, Andrew, Amuzu, Antoinette, Ong, Ken, Gaunt, Tom, Holmes, Michael V., Warren, Helen, Davies, Teri-Louise, Drenos, Fotios, Cooper, Jackie, Sofat, Reecha, Caulfield, Mark, Ebrahim, Shah, Lawlor, Debbie A., Talmud, Philippa J., Humphries, Steve E., Power, Christine, Hypponen, Elina, Richards, Marcus, Hardy, Rebecca ... Hingorani, Aroon D. (2013). Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. PLoS ONE, 8 (8) e71345, e71345. doi: 10.1371/journal.pone.0071345 |
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2013 Journal Article Loci influencing blood pressure identified using a cardiovascular gene-centric arrayGanesh, Santhi K., Tragante, Vinicius, Guo, Wei, Guo, Yiran, Lanktree, Matthew B., Smith, Erin N., Johnson, Toby, Castillo, Berta Almoguera, Barnard, John, Baumert, Jens, Chang, Yen-Pei Christy, Elbers, Clara C., Farrall, Martin, Fischer, Mary E., Gaunt, Nora Franceschini, H. Gho, Johannes M.I., Gieger, Christian, Gong, Yan, Isaacs, Aaron, Kleber, Marcus E., Leach, Irene Mateo, McDonough, Caitrin W., Meijs, Matthijs F.L., Mellander, Olle, Molony, Cliona M., Nolte, Ilja M., Price, Sandosh Padmanabhan, Rajagopalan, Ramakrishnan, Shaffer, Jonathan ... Asselbergs, Folkert W. (2013). Loci influencing blood pressure identified using a cardiovascular gene-centric array. Human Molecular Genetics, 22 (16) ddt177, 3394-3395. doi: 10.1093/hmg/ddt177 |
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2013 Journal Article Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markersShah T., Zabaneh D., Gaunt T., Swerdlow D.I., Shah S., Talmud P.J., Day I.N., Whittaker J., Holmes M.V., Sofat R., Humphries S.E., Kivimaki M., Kumari M., Hingorani A.D. and Casas J.P. (2013). Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. Circulation: Cardiovascular Genetics, 6 (2), 163-170. doi: 10.1161/CIRCGENETICS.112.964254 |
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2013 Journal Article Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studiesShah S., Casas J.P., Gaunt T.R., Cooper J., Drenos F., Zabaneh D., Swerdlow D.I., Shah T., Sofat R., Palmen J., Kumari M., Kivimaki M., Ebrahim S., Smith G.D., Lawlor D.A., Talmud P.J., Whittaker J., Day I.N.M., Hingorani A.D. and Humphries S.E. (2013). Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies. European Heart Journal, 34 (13), 972-981. doi: 10.1093/eurheartj/ehs243 |
