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2022

Journal Article

Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sources

Smith, Maree T., Kong, Dehui, Kuo, Andy, Imam, Mohammad Z. and Williams, Craig M. (2022). Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sources. Journal of Medicinal Chemistry, 65 (3) acs.jmedchem.0c01915, 1612-1661. doi: 10.1021/acs.jmedchem.0c01915

Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sources

2022

Book Chapter

Side effects of central analgesic drugs

Imam, M. Z., Kuo, A. and Smith, M. T. (2022). Side effects of central analgesic drugs. Drug discovery and evaluation: safety and pharmacokinetic assays. (pp. 1-24) Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-030-73317-9_70-1

Side effects of central analgesic drugs

2021

Journal Article

Sustained-release ketamine-loaded lipid-particulate system: in vivo assessment in mice

Xu, Weizhi, Maqbool, Faheem, Kumar, Vinod, Falconer, James R., Cui, Cedric S., Woodruff, Trent M., Borges, Karin, Whittaker, Andrew K., Smith, Maree T. and Han, Felicity Y. (2021). Sustained-release ketamine-loaded lipid-particulate system: in vivo assessment in mice. Drug Delivery and Translational Research, 12 (10), 2518-2526. doi: 10.1007/s13346-021-01093-3

Sustained-release ketamine-loaded lipid-particulate system: in vivo assessment in mice

2021

Journal Article

Pharmacological characterization of the chronic phase of the monoiodoacetate‐induced rat model of osteoarthritis pain in the knee joint

Han, Felicity Y., Brockman, David A., Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2021). Pharmacological characterization of the chronic phase of the monoiodoacetate‐induced rat model of osteoarthritis pain in the knee joint. Clinical and Experimental Pharmacology and Physiology, 48 (11) 1440-1681.13551, 1515-1522. doi: 10.1111/1440-1681.13551

Pharmacological characterization of the chronic phase of the monoiodoacetate‐induced rat model of osteoarthritis pain in the knee joint

2021

Journal Article

Editorial: verification of animal pain models by reverse translation

Caudle, Robert M., Smith, Maree Therese and Romero-Sandoval, E. Alfonso (2021). Editorial: verification of animal pain models by reverse translation. Frontiers in Pharmacology, 12 778880, 778880. doi: 10.3389/fphar.2021.778880

Editorial: verification of animal pain models by reverse translation

2021

Journal Article

Optimisation of a microfluidic method for the delivery of a small peptide

Han, Felicity Y., Xu, Weizhi, Kumar, Vinod, Cui, Cedric S., Li, Xaria, Jiang, Xingyu, Woodruff, Trent M., Whittaker, Andrew K. and Smith, Maree T. (2021). Optimisation of a microfluidic method for the delivery of a small peptide. Pharmaceutics, 13 (9) 1505, 1505. doi: 10.3390/pharmaceutics13091505

Optimisation of a microfluidic method for the delivery of a small peptide

2021

Book Chapter

Are all opioids the same?

Smith, Maree and Hogg, Malcolm (2021). Are all opioids the same?. Opioid therapy for pain: a practical guide for clinicians. (pp. 105-118) edited by Kok Eng Khor, Alex Sia and Mary Cardosa. Singapore, Singapore: Red Cells Imprint, SingHealth Academy.

Are all opioids the same?

2021

Journal Article

Assessment of the anti-allodynic and anti-hyperalgesic efficacy of a glycine transporter 2 inhibitor relative to pregabalin, duloxetine and indomethacin in a rat model of cisplatin-induced peripheral neuropathy

Kuo, Andy, Corradini, Laura, Nicholson, Janet R. and Smith, Maree T. (2021). Assessment of the anti-allodynic and anti-hyperalgesic efficacy of a glycine transporter 2 inhibitor relative to pregabalin, duloxetine and indomethacin in a rat model of cisplatin-induced peripheral neuropathy. Biomolecules, 11 (7) 940, 1-17. doi: 10.3390/biom11070940

Assessment of the anti-allodynic and anti-hyperalgesic efficacy of a glycine transporter 2 inhibitor relative to pregabalin, duloxetine and indomethacin in a rat model of cisplatin-induced peripheral neuropathy

2021

Journal Article

Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process

Xu, Weizhi, Zhao, Zonglan, Falconer, James, Whittaker, Andrew K., Popat, Amirali, Smith, Maree T., Kumeria, Tushar and Han, Felicity Y. (2021). Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process. Drug Delivery and Translational Research, 12 (3), 676-694. doi: 10.1007/s13346-021-00991-w

Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process

2021

Journal Article

Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methods

Park, Thomas S.W., Khan, Nemat, Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2021). Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methods. Clinical and Experimental Pharmacology and Physiology, 48 (1) 1440-1681.13402, 96-106. doi: 10.1111/1440-1681.13402

Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methods

2020

Journal Article

Use of microfluidics to fabricate bioerodable lipid hybrid nanoparticles containing hydromorphone or ketamine for the relief of intractable pain

Zhu, Minze, Whittaker, Andrew K., Jiang, Xingyu, Tang, Rupei, Li, Xuanyu, Xu, Weizhi, Fu, Changkui, Smith, Maree T. and Han, Felicity Y. (2020). Use of microfluidics to fabricate bioerodable lipid hybrid nanoparticles containing hydromorphone or ketamine for the relief of intractable pain. Pharmaceutical Research, 37 (10) 211, 1-12. doi: 10.1007/s11095-020-02939-0

Use of microfluidics to fabricate bioerodable lipid hybrid nanoparticles containing hydromorphone or ketamine for the relief of intractable pain

2020

Journal Article

Herbicides that target acetohydroxyacid synthase are potent inhibitors of the growth of drug resistant Candida auris

Agnew-Francis, Kylie A., Tang, Yu Cheng, Lin, Xin, Low, Yu Shang, Wun, Shun Jie, Kuo, Andy, Elias, S. M. A. Sayeed Ibn, Lonhienne, Thierry G., Condon, Nicholas, Pimentel, Bruna Natalia Alves da Silva, Vergani, Carlos, Smith, Maree T., Fraser, James A., Williams, Craig M. and Guddat, Luke W (2020). Herbicides that target acetohydroxyacid synthase are potent inhibitors of the growth of drug resistant Candida auris. ACS infectious diseases, 6 (11) acsinfecdis.0c00229, 2901-2912. doi: 10.1021/acsinfecdis.0c00229

Herbicides that target acetohydroxyacid synthase are potent inhibitors of the growth of drug resistant Candida auris

2020

Journal Article

Assessment of the anti-allodynic efficacy of a glycine transporter 2 inhibitor relative to pregabalin and duloxetine in a rat model of prostate cancer-induced bone pain

Imam, Mohammad Zafar, Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2020). Assessment of the anti-allodynic efficacy of a glycine transporter 2 inhibitor relative to pregabalin and duloxetine in a rat model of prostate cancer-induced bone pain. Pharmacological Reports, 72 (5), 1418-1425. doi: 10.1007/s43440-020-00145-8

Assessment of the anti-allodynic efficacy of a glycine transporter 2 inhibitor relative to pregabalin and duloxetine in a rat model of prostate cancer-induced bone pain

2020

Journal Article

Assessment of the anti‐hyperalgesic efficacy of J‐2156, relative to clinically available analgesic/adjuvant agents in a rat model of mild to moderate chronic mechanical low back pain (LBP)

Kuo, Andy, Lourdesamy, Jacintha, Nicholson, Janet R., Corradini, Laura and Maree, Smith T. (2020). Assessment of the anti‐hyperalgesic efficacy of J‐2156, relative to clinically available analgesic/adjuvant agents in a rat model of mild to moderate chronic mechanical low back pain (LBP). Clinical and Experimental Pharmacology and Physiology, 47 (12) 1440-1681.13383, 1912-1922. doi: 10.1111/1440-1681.13383

Assessment of the anti‐hyperalgesic efficacy of J‐2156, relative to clinically available analgesic/adjuvant agents in a rat model of mild to moderate chronic mechanical low back pain (LBP)

2020

Journal Article

Comparative studies of glial fibrillary acidic protein and brain‐derived neurotrophic factor expression in two transgenic mouse models of Alzheimer’s disease

Edwards, Stephen R., Khan, Nemat, Coulson, Elizabeth J. and Smith, Maree T. (2020). Comparative studies of glial fibrillary acidic protein and brain‐derived neurotrophic factor expression in two transgenic mouse models of Alzheimer’s disease. Clinical and Experimental Pharmacology and Physiology, 47 (10) 1440-1681.13363, 1740-1750. doi: 10.1111/1440-1681.13363

Comparative studies of glial fibrillary acidic protein and brain‐derived neurotrophic factor expression in two transgenic mouse models of Alzheimer’s disease

2020

Journal Article

Sustained-release ketamine-loaded nanoparticles fabricated by sequential nanoprecipitation

Han, Felicity Y., Liu, Yun, Kumar, Vinod, Xu, Weizhi, Yang, Guangze, Zhao, Chun-Xia, Woodruff, Trent M., Whittaker, Andrew K. and Smith, Maree T. (2020). Sustained-release ketamine-loaded nanoparticles fabricated by sequential nanoprecipitation. International Journal of Pharmaceutics, 581 119291, 119291. doi: 10.1016/j.ijpharm.2020.119291

Sustained-release ketamine-loaded nanoparticles fabricated by sequential nanoprecipitation

2020

Journal Article

In vitro profiling of opioid ligands using the cAMP formation inhibition assay and the β-arrestin2 recruitment assay: No two ligands have the same profile

Kuo, Andy, Magiera, Julia, Rethwan, Nursyazwani, Andersson, Åsa, Leen Lam, Ai, Wyse, Bruce, Meutermans, Wim, Lewis, Richard and Smith, Maree (2020). In vitro profiling of opioid ligands using the cAMP formation inhibition assay and the β-arrestin2 recruitment assay: No two ligands have the same profile. European Journal of Pharmacology, 872 172947, 172947. doi: 10.1016/j.ejphar.2020.172947

In vitro profiling of opioid ligands using the cAMP formation inhibition assay and the β-arrestin2 recruitment assay: No two ligands have the same profile

2020

Journal Article

Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphine

Imam, Mohammad Zafar, Kuo, Andy, Ghassabian, Sussan, Cai, Yunxin, Qin, Yajuan, Li, Tingyou and Smith, Maree T. (2020). Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphine. European Journal of Pharmacology, 871 172918, 172918. doi: 10.1016/j.ejphar.2020.172918

Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphine

2020

Journal Article

Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulants

Imam, Mohammad Zafar, Kuo, Andy and Smith, Maree T. (2020). Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulants. F1000Research, 9 91, 91. doi: 10.12688/f1000research.21738.1

Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulants

2019

Journal Article

Transcriptomic characterisation of the optimised rat model of Walker 256 breast cancer cell-induced bone pain

Shenoy, Priyank A., Kuo, Andy, Leparc, German, Hildebrandt, Tobias, Rust, Werner, Nicholson, Janet R., Corradini, Laura, Vetter, Irina and Smith, Maree T. (2019). Transcriptomic characterisation of the optimised rat model of Walker 256 breast cancer cell-induced bone pain. Clinical and Experimental Pharmacology and Physiology, 46 (12) 1440-1681.13165, 1201-1215. doi: 10.1111/1440-1681.13165

Transcriptomic characterisation of the optimised rat model of Walker 256 breast cancer cell-induced bone pain