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2014 Journal Article Four structural subclasses of the antivirulence drug target disulfide oxidoreductase DsbA provide a platform for design of subclass-specific inhibitorsMcMahon, Róisín M., Premkumar, Lakshmanane and Martin, Jennifer L. (2014). Four structural subclasses of the antivirulence drug target disulfide oxidoreductase DsbA provide a platform for design of subclass-specific inhibitors. Biochimica et Biophysica Acta: Proteins and Proteomics, In Press, Uncorrected Proof (8), 1-11. doi: 10.1016/j.bbapap.2014.01.013 |
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2014 Conference Publication Characterization of the alpha-proteobacteria Wolbachia pipientis protein disulphide machinery reveals a regulatory mechanism absent in gamma-proteobacteriaWalden, Patricia M., Halili, Maria A., Archbold, Julia K., Lindahl, Fredrik, Fairlie, David P., Inaba, Kenji and Martin, Jennifer L. (2014). Characterization of the alpha-proteobacteria Wolbachia pipientis protein disulphide machinery reveals a regulatory mechanism absent in gamma-proteobacteria. 28th Annual Symposium of the Protein-Society, San Diego, California, 27-30 July 2014. Hoboken, NJ, United States : Wiley-Blackwell. |
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2013 Journal Article Milligram quantities of homogeneous recombinant full-length mouse Munc18c from Escherichia coli culturesRehman, Asma, Jarrott, Russell J., Whitten, Andrew E., King, Gordon J., Hu, Shu-Hong, Christie, Michelle P., Collins, Brett M. and Martin, Jennifer L. (2013). Milligram quantities of homogeneous recombinant full-length mouse Munc18c from Escherichia coli cultures. PloS One, 8 (12) e83499, e83499.1-e83499.12. doi: 10.1371/journal.pone.0083499 |
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2013 Journal Article Structural insights into the role of the cyclic backbone in a squash trypsin inhibitorDaly, Norelle L., Thorstholm, Louise, Greenwood, Kathryn P., King, Gordon J., Rosengren, K. Johan, Heras, Begona, Martin, Jennifer L. and Craik, David J. (2013). Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor. Journal of Biological Chemistry, 288 (50), 36141-36148. doi: 10.1074/jbc.M113.528240 |
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2013 Journal Article The multidrug resistance IncA/C transferable plasmid encodes a novel domain swapped dimeric protein disulfide isomerasePremkumar, Lakshmanane, Kurth, Fabian, Neyer, Simon, Schembri, Mark A. and Martin, Jennifer L. (2013). The multidrug resistance IncA/C transferable plasmid encodes a novel domain swapped dimeric protein disulfide isomerase. Journal of Biological Chemistry, Papers in Press (5), 1-24. doi: 10.1074/jbc.M113.516898 |
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2013 Journal Article The alpha-proteobacteria Wolbachia pipientis protein disulfide machinery has a regulatory mechanism absent in gamma-proteobacteriaWalden, Patricia, Halili, Maria, Julia Archbold, Fredrik Lindahl, Fairlie, David P., Inaba, Kenji and Martin, Jennifer L. (2013). The alpha-proteobacteria Wolbachia pipientis protein disulfide machinery has a regulatory mechanism absent in gamma-proteobacteria. PloS One, 8 (11) e81440, e81440.1-e81440.9. doi: 10.1371/journal.pone.0081440 |
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2013 Journal Article Comparative sequence, structure and redox analyses of Klebsiella pneumoniae DsbA show that anti-virulence target DsbA enzymes fall into distinct classesKurth, Fabian, Rimmer, Kieran, Premkumar, Lakshmanane, Mohanty, Biswaranjan, Duprez, Wilko, Halili, Maria A., Shouldice, Stephen R., Heras, Begoña, Fairlie, David P., Scanlon, Martin J. and Martin, Jennifer L. (2013). Comparative sequence, structure and redox analyses of Klebsiella pneumoniae DsbA show that anti-virulence target DsbA enzymes fall into distinct classes. PloS One, 8 (11) e80210, e80210.1-e80210.15. doi: 10.1371/journal.pone.0080210 |
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2013 Journal Article Bread, Beer and Botox: the science behind the 2013 Nobel prize for medicineMartin, Jennifer Louise (2013, 10 08). Bread, Beer and Botox: the science behind the 2013 Nobel prize for medicine |
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2013 Journal Article Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidasesPremkumar, Lakshmanane, Heras, Begoña, Duprez, Wilko, Walden, Patricia, Halili, Maria, Kurth, Fabian, Fairlie, David P. and Martin, Jennifer L. (2013). Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases. Acta Crystallographica Section D: Biological Crystallography, 69 (10), 1981-1994. doi: 10.1107/S0907444913017800 |
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2013 Journal Article Interrogating fragments using a protein thermal shift assayMcMahon, Róisín M., Scanlon, Martin J. and Martin, Jennifer L. (2013). Interrogating fragments using a protein thermal shift assay. Australian Journal of Chemistry, 66 (12), 1502-1506. doi: 10.1071/CH13279 |
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2013 Journal Article Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteinsYu, Haijia, Rathore, Shailendra S., Lopez, Jamie A., Davis, Eric M., James, David E., Martin, Jennifer L. and Shen, Jingshi (2013). Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins. Proceedings of the National Academy of Sciences of the United States of America, 110 (35), E3271-E3280. doi: 10.1073/pnas.1311232110 |
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2013 Journal Article Disarming Burkholderia pseudomallei: structural and functional characterization of a disulfide oxidoreductase (DsbA) required for virulence in vivoIreland, Philip M., McMahon, Róisín M., Marshall, Laura E., Halili, Maria, Furlong, Emily, Tay, Stephanie, Martin, Jennifer L. and Sarkar-Tyson, Mitali (2013). Disarming Burkholderia pseudomallei: structural and functional characterization of a disulfide oxidoreductase (DsbA) required for virulence in vivo. Antioxidants & Redox Signaling, Fast Track (4), 1-12. doi: 10.1089/ars.2013.5375 |
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2013 Journal Article The Munc18-1 domain 3a loop is essential for neuroexocytosis but not for syntaxin-1A transport to the plasma membraneMartin, Sally, Tomatis, Vanesa M., Papadopulos, Andreas, Christie, Michelle P., Malintan, Nancy T., Gormal, Rachel S., Sugita, Shuzo, Martin, Jennifer L., Collins, Brett M. and Meunier, Frederic A. (2013). The Munc18-1 domain 3a loop is essential for neuroexocytosis but not for syntaxin-1A transport to the plasma membrane. Journal of Cell Science, 126 (11), 2353-2360. doi: 10.1242/jcs.126813 |
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2013 Journal Article The Arabidopsis B3 domain protein VERNALIZATION1 is involved in processes essential for development with structural and mutational studies revealing its DNA binding surfaceKing, Gordon J., Chanson, Aurelie H., McCallum, Emily J., Ohme-Takagi, Masaru, Byriel, Karl, Hill, Justine M., Martin, Jennifer L. and Mylne, Joshua S. (2013). The Arabidopsis B3 domain protein VERNALIZATION1 is involved in processes essential for development with structural and mutational studies revealing its DNA binding surface. Journal of Biological Chemistry, 288 (5), 3198-3207. doi: 10.1074/jbc.M112.438572 |
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2013 Journal Article The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidizedChen, Kai-En, Richards, Ayanthi A., Caradoc-Davies, Tom T., Vajjhala, Parimala R., Robin, Gautier, Lua, Linda H. L., Hill, Justine M., Schroder, Kate, Sweet, Matthew J., Kellie, Stuart, Kobe, Bostjan and Martin, Jennifer (2013). The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized. Acta Crystallographica Section D: Biological Crystallography, 69 (5), 774-784. doi: 10.1107/S0907444913001558 |
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2012 Journal Article Membrane curvature protein exhibits interdomain flexibility and binds a small GTPaseKing, Gordon J., Stoeckli, Jacqueline, Hu, Shu-Hong, Winnen, Brit, Duprez, Wilko G. A., Meoli, Christopher C., Junutula, Jagath R., Jarrott, Russell J., James, David E., Whitten, Andrew E. and Martin, Jennifer L. (2012). Membrane curvature protein exhibits interdomain flexibility and binds a small GTPase. Journal of Biological Chemistry, 287 (49), 40996-41006. doi: 10.1074/jbc.M112.349803 |
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2012 Journal Article Bacterial resistance warsMartin, Jennifer and Furlong, Emily (2012). Bacterial resistance wars. Biological Sciences Review, 25 (2), 27-29. |
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2012 Journal Article Professor Dame Louise Johnson: a personal perspective from a former studentMartin, Jenny (2012). Professor Dame Louise Johnson: a personal perspective from a former student. International Union of Crystallography |
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2012 Journal Article The 1.2 A resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin productionWalden, Patricia M., Heras, Begona, Chen, Kai-En, Halili, Maria A., Rimmer, Kieran, Sharma, Pooja, Scanlon, Martin J. and Martin, Jennifer L. (2012). The 1.2 A resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin production. Acta Crystallographica Section D-Biological Crystallography, 68 (10), 1290-1302. doi: 10.1107/S0907444912026388 |
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2012 Journal Article The weak complex between RhoGAP protein ARHGAP22 and signal regulatory protein 14-3-3 Has 1:2 stoichiometry and a single peptide binding modeHu, Shu-Hong, Whitten, Andrew E., King, Gordon J., Jones, Alun, Rowland, Alexander F., James, David E. and Martin, Jennifer L. (2012). The weak complex between RhoGAP protein ARHGAP22 and signal regulatory protein 14-3-3 Has 1:2 stoichiometry and a single peptide binding mode. Plos One, 7 (8) e41731, 41731-1-41731-11. doi: 10.1371/journal.pone.0041731 |
