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2000

Conference Publication

The side-chain classification of loops from high resolution protein crystal structures

Tran, T. T., Bourne, G. T., Golding, S., Meutermans, W. and Smythe, M. L. (2000). The side-chain classification of loops from high resolution protein crystal structures. 16th American Peptide symposium, Minneapolis, MN United States, 26 June - 1 July 1999. Dordrecht, Netherlands: Kluwer. doi: 10.1007/0-306-46881-6_130

The side-chain classification of loops from high resolution protein crystal structures

2000

Conference Publication

Synthesis of small cyclic peptides: An auxiliary approach to address the difficult cyclization problem

Meutermans, W., Golding, S., Bourne, G. T., Miranda, L. P., Dooley, M., Alewood, P. F. and Smythe, M. L. (2000). Synthesis of small cyclic peptides: An auxiliary approach to address the difficult cyclization problem. 16th American Peptide Symposium, Minneapolis, MN United States, 26 June - 1 July 1999. Dordrecht, Netherlands: Kluwer. doi: 10.1007/0-306-46881-6_75

Synthesis of small cyclic peptides: An auxiliary approach to address the difficult cyclization problem

2000

Journal Article

Exploring privileged structures: The combinatorial synthesis of cyclic peptides

Horton, DA, Bourne, GT and Smythe, ML (2000). Exploring privileged structures: The combinatorial synthesis of cyclic peptides. Molecular Diversity, 5 (4), 289-304. doi: 10.1023/A:1021365402751

Exploring privileged structures: The combinatorial synthesis of cyclic peptides

2000

Journal Article

Synthesis of difficult cyclic peptides by inclusion of a novel photolabile auxiliary in a ring contraction strategy

Scolastico, C., Manzoni, L., Meutermans, W. D.F., Golding, S. W., Bourne, G. T., Miranda, L. P., Dooley, M. J., Alewood, P. F. and Smythe, M. L. (2000). Synthesis of difficult cyclic peptides by inclusion of a novel photolabile auxiliary in a ring contraction strategy. Chemtracts, 13 (7), 443-446.

Synthesis of difficult cyclic peptides by inclusion of a novel photolabile auxiliary in a ring contraction strategy

1999

Journal Article

A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1

Bourne, GT, Meutermans, WDF, Alewood, PF, McGeary, RP, Watson, AA and Smythe, ML (1999). A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1. Journal of Organic Chemistry, 64 (9), 3095-3101. doi: 10.1021/jo9818780

A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1

1999

Journal Article

The development of solid phase protocols for a backbone amide linker and its application to the Boc-based assembly of linear peptides

Bourne, G. T., Meutermans, W. D. F. and Smythe, M. L. (1999). The development of solid phase protocols for a backbone amide linker and its application to the Boc-based assembly of linear peptides. Tetrahedron Letters, 40 (40), 7271-7274. doi: 10.1016/S0040-4039(99)01473-2

The development of solid phase protocols for a backbone amide linker and its application to the Boc-based assembly of linear peptides

1997

Journal Article

Proteolytic degradation of host hemoglobin by schistosomes

Brindley, Paul J., Kalinna, Bernd H., Dalton, John P., Day, Sharon R., Wong, Joanna Y. M., Smythe, Mark L. and McManus, Donald P. (1997). Proteolytic degradation of host hemoglobin by schistosomes. Molecular and Biochemical Parasitology, 89 (1), 1-9. doi: 10.1016/S0166-6851(97)00098-4

Proteolytic degradation of host hemoglobin by schistosomes

1997

Journal Article

Synthesis of alpha-aspartyl-containing cyclic peptides

Meutermans, WDF, Alewood, PF, Bourne, GT, Hawkins, B and Smythe, ML (1997). Synthesis of alpha-aspartyl-containing cyclic peptides. Letters In Peptide Science, 4 (2), 79-84. doi: 10.1023/A:1008878017315

Synthesis of alpha-aspartyl-containing cyclic peptides

1997

Journal Article

Synthesis of α-aspartyl-containing cyclic peptides

Meutermans W.D.F., Alewood P.F., Bourne G.T., Hawkins B. and Smythe M.L. (1997). Synthesis of α-aspartyl-containing cyclic peptides. Letters in Peptide Science, 4 (2), 79-84. doi: 10.1007/BF02443518

Synthesis of α-aspartyl-containing cyclic peptides

1996

Journal Article

VALIDATE: A new method for the receptor-based prediction of binding affinities of novel ligands

Head, RD, Smythe, ML, Oprea, TI, Waller, CL, Green, SM and Marshall, GR (1996). VALIDATE: A new method for the receptor-based prediction of binding affinities of novel ligands. Journal of the American Chemical Society, 118 (16), 3959-3969. doi: 10.1021/ja9539002

VALIDATE: A new method for the receptor-based prediction of binding affinities of novel ligands

1996

Journal Article

Electrochemical cyclization of dipeptides to form novel bicyclic, reverse-turn peptidomimetics. 2. Synthesis and conformational analysis of 6,5-bicyclic systems

Slomezynska, Urszula, Chalmers, David K., Cornille, Fabrice, Smythe, Mark L., Beusen, Denise D., Moeller, Kevin D. and Marshall, Garland R. (1996). Electrochemical cyclization of dipeptides to form novel bicyclic, reverse-turn peptidomimetics. 2. Synthesis and conformational analysis of 6,5-bicyclic systems. Journal of Organic Chemistry, 61 (4), 1198-1204. doi: 10.1021/jo950898o

Electrochemical cyclization of dipeptides to form novel bicyclic, reverse-turn peptidomimetics. 2. Synthesis and conformational analysis of 6,5-bicyclic systems

1995

Journal Article

The Molten Helix: Effects of Solvation on the α- to 310-Helical Transition

Smythe M.L., Huston S.E. and Marshall G.R. (1995). The Molten Helix: Effects of Solvation on the α- to 310-Helical Transition. Journal of the American Chemical Society, 117 (20), 5445-5452. doi: 10.1021/ja00125a003

The Molten Helix: Effects of Solvation on the α- to 310-Helical Transition

1995

Journal Article

Electrochemical Cyclization of Dipeptides toward Novel Bicyclic, Reverse-Turn Peptidomimetics. 1. Synthesis and Conformational Analysis of 7,5-Bicyclic Systems

Cornille F., Slomczynska U., Smythe M.L., Marshall G.R., Beusen D.D., Marshall G.R., Moeller K.D., Slomczynska U., Slomczynska U., Cornille F. and Smythe M.L. (1995). Electrochemical Cyclization of Dipeptides toward Novel Bicyclic, Reverse-Turn Peptidomimetics. 1. Synthesis and Conformational Analysis of 7,5-Bicyclic Systems. Journal of Organic Chemistry, 117 (3), 909-917. doi: 10.1021/ja00108a007

Electrochemical Cyclization of Dipeptides toward Novel Bicyclic, Reverse-Turn Peptidomimetics. 1. Synthesis and Conformational Analysis of 7,5-Bicyclic Systems

1995

Journal Article

α-Helical versus 310-Helical Conformation of Alanine-Based Peptides in Aqueous Solution: An Electron Spin Resonance Investigation

Smythe M.L., Nakaie C.R. and Marshall G.R. (1995). α-Helical versus 310-Helical Conformation of Alanine-Based Peptides in Aqueous Solution: An Electron Spin Resonance Investigation. Journal of the American Chemical Society, 117 (42), 10555-10562. doi: 10.1021/ja00147a018

α-Helical versus 310-Helical Conformation of Alanine-Based Peptides in Aqueous Solution: An Electron Spin Resonance Investigation

1994

Journal Article

DESIGN AND SYNTHESIS OF A BIOLOGICALLY-ACTIVE ANTIBODY MIMIC BASED ON AN ANTIBODY-ANTIGEN CRYSTAL-STRUCTURE

SMYTHE, ML and VONITZSTEIN, M (1994). DESIGN AND SYNTHESIS OF A BIOLOGICALLY-ACTIVE ANTIBODY MIMIC BASED ON AN ANTIBODY-ANTIGEN CRYSTAL-STRUCTURE. Journal of the American Chemical Society, 116 (7), 2725-2733. doi: 10.1021/ja00086a005

DESIGN AND SYNTHESIS OF A BIOLOGICALLY-ACTIVE ANTIBODY MIMIC BASED ON AN ANTIBODY-ANTIGEN CRYSTAL-STRUCTURE

1993

Journal Article

FREE-ENERGY PROFILE OF A 3(10)-HELICAL TO ALPHA-HELICAL TRANSITION OF AN OLIGOPEPTIDE IN VARIOUS SOLVENTS

SMYTHE, ML, HUSTON, SE and MARSHALL, GR (1993). FREE-ENERGY PROFILE OF A 3(10)-HELICAL TO ALPHA-HELICAL TRANSITION OF AN OLIGOPEPTIDE IN VARIOUS SOLVENTS. Journal of the American Chemical Society, 115 (24), 11594-11595. doi: 10.1021/ja00077a067

FREE-ENERGY PROFILE OF A 3(10)-HELICAL TO ALPHA-HELICAL TRANSITION OF AN OLIGOPEPTIDE IN VARIOUS SOLVENTS

1993

Journal Article

RATIONAL DESIGN OF POTENT SIALIDASE-BASED INHIBITORS OF INFLUENZA-VIRUS REPLICATION

VONITZSTEIN, M, WU, WY, KOK, GB, PEGG, MS, DYASON, JC, JIN, B, PHAN, TV, SMYTHE, ML, WHITE, HF, OLIVER, SW, COLMAN, PM, VARGHESE, JN, RYAN, DM, WOODS, JM, BETHELL, RC, HOTHAM, VJ, CAMERON, JM and PENN, CR (1993). RATIONAL DESIGN OF POTENT SIALIDASE-BASED INHIBITORS OF INFLUENZA-VIRUS REPLICATION. Nature, 363 (6428), 418-423. doi: 10.1038/363418a0

RATIONAL DESIGN OF POTENT SIALIDASE-BASED INHIBITORS OF INFLUENZA-VIRUS REPLICATION