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2014

Conference Publication

Integrated genome wide DNA methylation and gene expression analysis identifies subgroups of colorectal cancer with distinct molecular and clinical features

Dumenil, T. D., Klein, K., Wockner, L. F., Mckeone, D. M., Bowdler, L. M., Montgomery, G. W., Leggett, B. A. and Whitehall, V. L. J. (2014). Integrated genome wide DNA methylation and gene expression analysis identifies subgroups of colorectal cancer with distinct molecular and clinical features. Australian Gastroenterology Week 2014, Broadbeach, QLD Australia, 22‐24 October 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.

Integrated genome wide DNA methylation and gene expression analysis identifies subgroups of colorectal cancer with distinct molecular and clinical features

2014

Conference Publication

A clinicopathological and molecular appraisal of a large series of traditional serrated adenomas

Bettington, M., Walker, N., Brown, I., Rosty, C., Clouston, A., McKeone, D., Pearson, S-A, Leggett, B. and Whitehall, V. (2014). A clinicopathological and molecular appraisal of a large series of traditional serrated adenomas. 103rd Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP), San Diego, United States, Mar 01-07, 2014. London United Kingdom: Nature Publishing Group. doi: 10.1038/labinvest.2014.22

A clinicopathological and molecular appraisal of a large series of traditional serrated adenomas

2013

Journal Article

Prevalence of serrated polyps: implications for significance as colorectal cancer precursors

Tutticci, Nicholas J., Hewett, David G. and Leggett, Barbara A. (2013). Prevalence of serrated polyps: implications for significance as colorectal cancer precursors. Colorectal Cancer, 2 (6), 535-547. doi: 10.2217/CRC.13.70

Prevalence of serrated polyps: implications for significance as colorectal cancer precursors

2013

Journal Article

PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in Colorectal cancer

Day, Fiona L., Jorissen, Robert N., Lipton, Lara, Mouradov, Dmitri, Sakthianandeswaren, Anuratha, Christie, Michael, Li, Shan, Tsui, Cary, Tie, Jeannie, Desai, Jayesh, Xu, Zheng-Zhou, Molloy, Peter, Whitehall, Vicki, Leggett, Barbara A., Jones, Ian T., McLaughlin, Stephen, Ward, Robyn L., Hawkins, Nicholas J., Ruszkiewicz, Andrew R., Moore, James, Busam, Dana, Zhao, Qi, Strausberg, Robert L., Gibbs, Peter and Sieber, Oliver M. (2013). PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in Colorectal cancer. Clinical Cancer Research, 19 (12), 3285-3296. doi: 10.1158/1078-0432.CCR-12-3614

PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in Colorectal cancer

2013

Journal Article

Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management

Rosty, Christophe, Hewett, David G., Brown, Ian S., Leggett, Barbara A. and Whitehall, Vicki L. J. (2013). Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management. Journal of Gastroenterology, 48 (3), 287-302. doi: 10.1007/s00535-012-0720-y

Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management

2013

Journal Article

Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome

Win, Aung Ko, Lindor, Noralane M., Winship, Ingrid, Tucker, Katherine M., Buchanan, Daniel D., Young, Joanne P., Rosty, Christophe, Leggett, Barbara, Giles, Graham G., Goldblatt, Jack, Macrae, Finlay A., Parry, Susan, Kalady, Matthew F., Baron, John A., Ahnen, Dennis J., Le Marchand, Loic, Gallinger, Steven, Haile, Robert W., Newcomb, Polly A., Hopper, John L. and Jenkins, Mark A. (2013). Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome. Journal of the National Cancer Institute, 105 (4), 274-279. doi: 10.1093/jnci/djs525

Risks of colorectal and other cancers after endometrial cancer for women with Lynch syndrome

2013

Journal Article

The serrated pathway to colorectal carcinoma: current concepts and challenges

Bettington, Mark, Walker, Neal, Clouston, Andrew, Brown, Ian, Leggett, Barbara and Whitehall, Vicki (2013). The serrated pathway to colorectal carcinoma: current concepts and challenges. Histopathology, 62 (3), 367-386. doi: 10.1111/his.12055

The serrated pathway to colorectal carcinoma: current concepts and challenges

2012

Journal Article

Chromosomal instability in BRAF mutant, microsatellite stable colorectal cancers

Bond, Catherine E., Umapathy, Aarti, Buttenshaw, Ron L., Wockner, Leesa, Leggett, Barbara A. and Whitehall, Vicki L. J. (2012). Chromosomal instability in BRAF mutant, microsatellite stable colorectal cancers. Plos One, 7 (10) e47483, e47483.1-e47483.9. doi: 10.1371/journal.pone.0047483

Chromosomal instability in BRAF mutant, microsatellite stable colorectal cancers

2012

Journal Article

Risks of primary extracolonic cancers following colorectal cancer in lynch syndrome

Win, Aung Ko, Lindor, Noralane M., Young, Joanne P., Macrae, Finlay A., Young, Graeme P., Williamson, Elizabeth, Parry, Susan, Goldblatt, Jack, Lipton, Lara, Winship, Ingrid, Leggett, Barbara, Tucker, Katherine M., Giles, Graham G., Buchanan, Daniel D., Clendenning, Mark, Rosty, Christophe, Arnold, Julie, Levine, A. Joan, Haile, Robert W., Gallinger, Steven, Le Marchand, Loic, Newcomb, Polly A., Hopper, John L. and Jenkins, Mark A. (2012). Risks of primary extracolonic cancers following colorectal cancer in lynch syndrome. Journal of the National Cancer Institute, 104 (18), 1363-1372. doi: 10.1093/jnci/djs351

Risks of primary extracolonic cancers following colorectal cancer in lynch syndrome

2012

Journal Article

Oncogenic PIK3CA mutations in colorectal cancers and polyps

Whitehall, Vicki L. J., Rickman, Celestine, Bond, Catherine E., Ramsnes, Ingunn, Greco, Sonia A., Umapathy, Aarti, McKeone, Diane, Faleiro, Rebecca J., Buttenshaw, Ron L., Worthley, Daniel L., Nayler, Sam, Zhao, Zhen Zhen, Montgomery, Grant W., Mallitt, Kylie-Ann, Jass, Jeremy R., Matsubara, Nagahide, Notohara, Kenji, Ishii, Tatsuhiro and Leggett, Barbara A. (2012). Oncogenic PIK3CA mutations in colorectal cancers and polyps. International Journal of Cancer, 131 (4), 813-820. doi: 10.1002/ijc.26440

Oncogenic PIK3CA mutations in colorectal cancers and polyps

2012

Conference Publication

The prevalence and predictors of proximal serrated polyps in routine clinical practice: a prospective observational study

Tutticci, Nicholas J., Croese, John, Kanowski, Peter, Skoien, Richard, Leggett, Barbara and Hewett, David G. (2012). The prevalence and predictors of proximal serrated polyps in routine clinical practice: a prospective observational study. Australian Gastroenterology Week 2012, Adelaide, SA, Australia, 16-19 October 2012. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/j.1440-1746.2011.07251_3.x

The prevalence and predictors of proximal serrated polyps in routine clinical practice: a prospective observational study

2011

Journal Article

Microsatellite instability: Detection and management in sporadic colorectal cancer

Whitehall, Vicki and Leggett, Barbara (2011). Microsatellite instability: Detection and management in sporadic colorectal cancer. Journal of Gastroenterology and Hepatology, 26 (12), 1697-1699. doi: 10.1111/j.1440-1746.2011.06932.x

Microsatellite instability: Detection and management in sporadic colorectal cancer

2011

Journal Article

Determining the frequency of de novo germline mutations in DNA mismatch repair genes

Win, Aung Ko, Jenkins, Mark A., Buchanan, Daniel D., Clendenning, Mark, Young, Joanne P., Giles, Graham G., Goldblatt, Jack, Leggett, Barbara A., Hopper, John L., Thibodeau, Stephen N. and Lindor, Noralane M. (2011). Determining the frequency of de novo germline mutations in DNA mismatch repair genes. Journal of Medical Genetics, 48 (8), 530-534. doi: 10.1136/jmedgenet-2011-100082

Determining the frequency of de novo germline mutations in DNA mismatch repair genes

2011

Journal Article

Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: The advantage of more extensive colon surgery

Parry, Susan, Win, Aung Ko, Parry, Bryan, Macrae, Finlay A., Gurrin, Lyle C., Church, James M., Baron, John A., Giles, Graham G., Leggett, Barbara A., Winship, Ingrid, Lipton, Lara, Young, Graeme P., Young, Joanne P., Lodge, Caroline J., Southey, Melissa C., Newcomb, Polly A., Le Marchand, Loic, Haile, Robert W., Lindor, Noralane M., Gallinger, Steven, Hopper, John L. and Jenkins, Mark A. (2011). Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: The advantage of more extensive colon surgery. Gut, 60 (7), 950-957. doi: 10.1136/gut.2010.228056

Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: The advantage of more extensive colon surgery

2011

Journal Article

Numerical ecology validates a biogeographical distribution and gender-based effect on mucosa-associated bacteria along the human colon

de Carcer, Daniel Aguirre, Ó Cuív, Páraic, Wang, Tingting, Kang, Seungha, Worthley, Daniel, Whitehall, Vicki, Gordon, Iain, McSweeney, Chris, Leggett, Barbara and Morrison, Mark (2011). Numerical ecology validates a biogeographical distribution and gender-based effect on mucosa-associated bacteria along the human colon. ISME Journal, 5 (5), 801-809. doi: 10.1038/ismej.2010.177

Numerical ecology validates a biogeographical distribution and gender-based effect on mucosa-associated bacteria along the human colon

2011

Journal Article

Tubular adenomas with minor villous changes show molecular features characteristic of tubulovillous adenomas

Ishii, Tatsushiro, Notohara, Kenji, Umapathy, Aarti, Mallitt, Kylie-Ann, Chikuba, Hiroshi, Moritani, Yukitoshi, Tanaka, Noriaki, Rosty, Christophe, Matsubara, Nagahide, Jass, Jeremy, Leggett, Barbara and Whitehall, Vicki (2011). Tubular adenomas with minor villous changes show molecular features characteristic of tubulovillous adenomas. American Journal of Surgical Pathology, 35 (2), 212-220. doi: 10.1097/PAS.0b013e318205df20

Tubular adenomas with minor villous changes show molecular features characteristic of tubulovillous adenomas

2011

Journal Article

The effects from DNA extraction methods on the evaluation of microbial diversity associated with human colonic tissue

Ó Cuív, Páraic, de Carcer, Daniel Aguirre, Jones, Michelle, Klaassens, Eline S., Worthley, Daniel L., Whitehall, Vicki L. J., Kang, Seungha, McSweeney, Christopher S., Leggett, Barbara A. and Morrison, Mark (2011). The effects from DNA extraction methods on the evaluation of microbial diversity associated with human colonic tissue. Microbial Ecology, 61 (2), 353-362. doi: 10.1007/s00248-010-9771-x

The effects from DNA extraction methods on the evaluation of microbial diversity associated with human colonic tissue

2011

Conference Publication

Prevalence and variable detection rates of serrated polyps during colonoscopy

Kiel, N. J., Smith, A. J., Leggett, B. A., Appleyard, M. N. and Hewett, D. G. (2011). Prevalence and variable detection rates of serrated polyps during colonoscopy. Australian Gastroenterology Week 2011, Brisbane, Australia, 12-15 September 2011. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1746.2011.06821.x

Prevalence and variable detection rates of serrated polyps during colonoscopy

2011

Journal Article

p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers

Bond, Catherine E., Umapathy, Aarti, Ramsnes, Ingunn, Greco, Sonia A., Zhao, Zhen Zhen, Mallitt, Kylie-Ann, Buttenshaw, Ron L., Montgomery, Grant W., Leggett, Barbara A. and Whitehall, Vicki L.J. (2011). p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers. International Journal of Cancer, 130 (7), 1567-1576. doi: 10.1002/ijc.26175

p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers

2010

Journal Article

Repeat participation in colorectal cancer screening utilizing fecal occult blood testing: A community-based project in a rural setting

Janda, Monika, Hughes, Karen L., Auster, Josephine F., Leggett, Barbara A. and Newman, Beth M. (2010). Repeat participation in colorectal cancer screening utilizing fecal occult blood testing: A community-based project in a rural setting. Journal of Gastroenterology and Hepatology, 25 (10), 1661-1667. doi: 10.1111/j.1440-1746.2010.06405.x

Repeat participation in colorectal cancer screening utilizing fecal occult blood testing: A community-based project in a rural setting