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2024 Journal Article Alcohol does not impact chronic hepatitis C treatment outcomes but increases risk for progressive liver disease: Findings from a prospective multicentre Australian study (OPERA-C)Clark, Paul J, Valery, Patricia C, Strasser, Simone I, Weltman, Martin, Thompson, Alex, Levy, Miriam T, Leggett, Barbara, Zekry, Amany, Rong, Julian, Sinclair, Marie, George, Jacob, Sievert, William, MacQuillan, Gerry, Tse, Edmund, Nicoll, Amanda, Wade, Amanda, Cheng, Wendy and Roberts, Stuart K (2024). Alcohol does not impact chronic hepatitis C treatment outcomes but increases risk for progressive liver disease: Findings from a prospective multicentre Australian study (OPERA-C). Drug and Alcohol Review, 43 (6), 1559-1572. doi: 10.1111/dar.13914 |
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2024 Journal Article Rising hospital admissions for alcohol-related cirrhosis and the impact of sex and comorbidity – a data linkage studySarraf, B., Skoien, R., Hartel, G., O'Beirne, J., Clark, P. J., Collins, L., Leggett, B., Powell, E. E. and Valery, P. C. (2024). Rising hospital admissions for alcohol-related cirrhosis and the impact of sex and comorbidity – a data linkage study. Public Health, 232, 178-187. doi: 10.1016/j.puhe.2024.04.030 |
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2024 Journal Article Spontaneous remission of Cronkhite-Canada syndrome without immunosuppressive medication in the context of decompensated cirrhosis: A case reportDeacon, Anthony J., Hoey, Paris, Grimpen, Florian, Francis, Leo, Brown, Ian and Leggett, Barbara (2024). Spontaneous remission of Cronkhite-Canada syndrome without immunosuppressive medication in the context of decompensated cirrhosis: A case report. Clinical Case Reports, 12 (6) e8985, e8985. doi: 10.1002/ccr3.8985 |
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2024 Journal Article High prevalence of diabetes among young First Nations Peoples with metabolic dysfunction-associated steatotic liver disease: a population-based study in AustraliaValery, Patricia C., Roche, Shruti, Brown, Catherine, O’Beirne, James, Hartel, Gunter, Leggett, Barbara, Skoien, Richard and Powell, Elizabeth E. (2024). High prevalence of diabetes among young First Nations Peoples with metabolic dysfunction-associated steatotic liver disease: a population-based study in Australia. International Journal for Equity in Health, 23 (1) 84, 1-11. doi: 10.1186/s12939-024-02153-z |
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2024 Journal Article Efficacy, safety, and pharmacokinetics of capsid assembly modulator linvencorvir plus standard of care in chronic hepatitis B patientsHou, Jinlin, Gane, Edward, Balabanska, Rozalina, Zhang, Wenhong, Zhang, Jiming, Lim, Tien Huey, Xie, Qing, Yeh, Chau-Ting, Yang, Sheng-Shun, Liang, Xieer, Komolmit, Piyawat, Leerapun, Apinya, Xue, Zenghui, Chen, Ethan, Zhang, Yuchen, Xie, Qiaoqiao, Chang, Ting-Tsung, Hu, Tsung-Hui, Lim, Seng Gee, Chuang, Wan-Long, Leggett, Barbara, Bo, Qingyan, Zhou, Xue, Triyatni, Miriam, Zhang, Wen and Yuen, Man-Fung (2024). Efficacy, safety, and pharmacokinetics of capsid assembly modulator linvencorvir plus standard of care in chronic hepatitis B patients. Clinical and Molecular Hepatology, 30 (2), 191-205. doi: 10.3350/cmh.2023.0422 |
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2024 Journal Article Broadening and strengthening the health providers caring for patients with chronic hepatitis C may improve continuity of careClark, Paul J., Valery, Patricia C., Strasser, Simone I., Weltman, Martin, Thompson, Alex, Levy, Miriam T., Leggett, Barbara, Zekry, Amany, Rong, Julian, Sinclair, Marie, George, Jacob, Bollipo, Steven, McGarity, Bruce, Sievert, William, MacQuillan, Gerry, Tse, Edmund, Nicoll, Amanda, Wade, Amanda, Cheng, Wendy and Roberts, Stuart K. (2024). Broadening and strengthening the health providers caring for patients with chronic hepatitis C may improve continuity of care. Journal of Gastroenterology and Hepatology, 39 (3), 568-575. doi: 10.1111/jgh.16440 |
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2024 Journal Article Lack of complete biochemical response in autoimmune hepatitis leads to adverse outcome: First report of the IAIHG retrospective registrySlooter, Charlotte D., Van Den Brand, Floris F., Lleo, Ana, Colapietro, Francesca, Lenzi, Marco, Muratori, Paolo, Kerkar, Nanda, Dalekos, George N., Zachou, Kalliopi, Lucena, M. Isabel, Robles-Díaz, Mercedes, Di Zeo-Sánchez, Daniel E., Andrade, Raúl J., Montano-Loza, Aldo J., Lytvyak, Ellina, Lissenberg-Witte, Birgit I., Maisonneuve, Patrick, Bouma, Gerd, MacEdo, Guilherme, Liberal, Rodrigo, De Boer, Ynto S., Almasio, P., Alvarez, F., Andrade, R., Arikan, C., Assis, D., Bardou-Jacquet, E., Biewenga, M., Van Hoek, B. ... Kuijvenhoven, J. (2024). Lack of complete biochemical response in autoimmune hepatitis leads to adverse outcome: First report of the IAIHG retrospective registry. Hepatology, 79 (3), 538-550. doi: 10.1097/HEP.0000000000000589 |
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2023 Journal Article Improving palliative and supportive care in advanced cirrhosis: the HepatoCare model of integrated collaborative careKearney, Alison, Tiwari, Neha, Cullen, Olivia, Legg, Amy, Arbi, Ismail, Douglas, Carol, Leggett, Barbara, Fenech, Mary, Mina, Joanne, Hoey, Paris and Skoien, Richard (2023). Improving palliative and supportive care in advanced cirrhosis: the HepatoCare model of integrated collaborative care. Internal Medicine Journal, 53 (11), 1963-1971. doi: 10.1111/imj.16248 |
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2023 Journal Article Diabetes mellitus and the progression of non‐alcoholic fatty liver disease to decompensated cirrhosis: a retrospective cohort studyO'Beirne, James, Skoien, Richard, Leggett, Barbara A., Hartel, Gunter F., Gordon, Louisa G., Powell, Elizabeth E. and Valery, Patricia C. (2023). Diabetes mellitus and the progression of non‐alcoholic fatty liver disease to decompensated cirrhosis: a retrospective cohort study. Medical Journal of Australia, 219 (8), 358-365. doi: 10.5694/mja2.52104 |
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2023 Journal Article Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled studyHirschfield, Gideon M., Shiffman, Mitchell L., Gulamhusein, Aliya, Kowdley, Kris V., Vierling, John M., Levy, Cynthia, Kremer, Andreas E., Zigmond, Ehud, Andreone, Pietro, Gordon, Stuart C., Bowlus, Christopher L., Lawitz, Eric J., Aspinall, Richard J., Pratt, Daniel S., Raikhelson, Karina, Gonzalez-Huezo, Maria S., Heneghan, Michael A., Jeong, Sook-Hyang, Ladrón de Guevara, Alma L., Mayo, Marlyn J., Dalekos, George N., Drenth, Joost P H, Janczewska, Ewa, Leggett, Barbara A., Nevens, Frederik, Vargas, Victor, Zuckerman, Eli, Corpechot, Christophe, Fassio, Eduardo ... McWherter, Charles A. (2023). Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study. Hepatology, 78 (2), 397-415. doi: 10.1097/HEP.0000000000000395 |
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2023 Journal Article Post-colonoscopy cancer rate at a tertiary referral hospital in Australia: a data linkage analysisLamba, Mehul, Khaing, Myat Myat, Ma, Xiaomin, Ryan, Kimberley, Appleyard, Mark, Leggett, Barbara and Grimpen, Florian (2023). Post-colonoscopy cancer rate at a tertiary referral hospital in Australia: a data linkage analysis. Journal of Gastroenterology and Hepatology, 38 (5), 740-746. doi: 10.1111/jgh.16077 |
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2022 Journal Article Comparative analysis of Illumina Mouse Methylation BeadChip and reduced-representation bisulfite sequencing for routine DNA methylation analysisFennell, Lochlan J., Hartel, Gunter, McKeone, Diane M., Bond, Catherine E., Kane, Alexandra, Leggett, Barbara A., Patch, Ann-Marie and Whitehall, Vicki L.J. (2022). Comparative analysis of Illumina Mouse Methylation BeadChip and reduced-representation bisulfite sequencing for routine DNA methylation analysis. Cell Reports Methods, 2 (11) 100323, 1-14. doi: 10.1016/j.crmeth.2022.100323 |
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2022 Journal Article Clinicopathological correlates of dysplastic sessile serrated lesion: a prospective cohort study with a high detection rateLamba, Mehul, Brown, Ian, Bettington, Mark, Ryan, Kimberley, Hanigan, Katherine, Lasenby, Kay, Dixon, Alicia, Grimpen, Florian, Gan, Chun, Tutticci, Nicholas, Appleyard, Mark and Leggett, Barbara (2022). Clinicopathological correlates of dysplastic sessile serrated lesion: a prospective cohort study with a high detection rate. Gastro Hep Advances, 1 (3), 313-320. doi: 10.1016/j.gastha.2021.12.010 |
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2021 Journal Article Braf mutation induces rapid neoplastic transformation in the aged and aberrantly methylated intestinal epitheliumFennell, Lochlan, Kane, Alexandra, Liu, Cheng, McKeone, Diane, Hartel, Gunter, Su, Chang, Bond, Catherine, Bettington, Mark, Leggett, Barbara and Whitehall, Vicki (2021). Braf mutation induces rapid neoplastic transformation in the aged and aberrantly methylated intestinal epithelium. Gut, 71 (6) 322166, 1127-1140. doi: 10.1136/gutjnl-2020-322166 |
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2021 Journal Article Association of Fusobacterium nucleatum with specific T-cell subsets in the colorectal carcinoma microenvironmentBorowsky, Jennifer, Haruki, Koichiro, Lau, Mai Chan, Costa, Andressa Dias, Vayrynen, Juha P., Ugai, Tomotaka, Arima, Kota, Da Silva, Annacarolina, Felt, Kristen D., Zhao, Melissa, Gurjao, Carino, Twombly, Tyler S., Fujiyoshi, Kenji, Vayrynen, Sara A., Hamada, Tsuyoshi, Mima, Kosuke, Bullman, Susan, Harrison, Tabitha A., Phipps, Amanda I., Peters, Ulrike, Ng, Kimmie, Meyerhardt, Jeffrey A., Song, Mingyang, Giovannucci, Edward L., Wu, Kana, Zhang, Xuehong, Freeman, Gordon J., Huttenhower, Curtis, Garrett, Wendy S. ... Ogino, Shuji (2021). Association of Fusobacterium nucleatum with specific T-cell subsets in the colorectal carcinoma microenvironment. Clinical Cancer Research, 27 (10), 2816-2826. doi: 10.1158/1078-0432.CCR-20-4009 |
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2021 Conference Publication Clinicopathological Correlates Of Dysplastic Change In Sessile Serrated LesionsLamba, Mehul, Ryan, Kimberley, Brown, Ian, Bettington, Mark, Hanigan, Katherine, Gan, Chun H., Grimpen, Florian, Appleyard, Mark and Leggett, Barbara (2021). Clinicopathological Correlates Of Dysplastic Change In Sessile Serrated Lesions. Digestive Disease Week (DDW) 2021, Online, 21-23 May 2021. Philadelphia, PA United States: Elsevier. doi: 10.1016/s0016-5085(21)02134-x |
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2021 Journal Article Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasiaKane, Alexandra M., Liu, Cheng, Fennell, Lochlan J., McKeone, Diane M., Bond, Catherine E., Pollock, Pamela M., Young, Graeme, Leggett, Barbara A. and Whitehall, Vicki L. J. (2021). Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasia. British Journal of Cancer, 124 (11), 1820-1827. doi: 10.1038/s41416-021-01339-4 |
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2021 Journal Article Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical studyKane, Alexandra M., Liu, Cheng, Akhter, Dewan T., McKeone, Diane M., Bell, Craig A., Thurecht, Kristofer J., Leggett, Barbara A. and Whitehall, Vicki L. J. (2021). Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study. Digestive Diseases and Sciences, 66 (12), 4326-4332. doi: 10.1007/s10620-020-06752-y |
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2020 Journal Article Pathways to a cancer-free future: a protocol for modelled evaluations to minimise the future burden of colorectal cancer in AustraliaFeletto, Eleonora, Lew, Jie-Bin, Worthington, Joachim, He, Emily, Caruana, Michael, Butler, Katherine, Hui, Harriet, Taylor, Natalie, Banks, Emily, Barclay, Karen, Broun, Kate, Butt, Alison, Carter, Rob, Cuff, Jeff, Dessaix, Anita, Ee, Hooi, Emery, Jon, Frayling, Ian M., Grogan, Paul, Holden, Carol, Horn, Christopher, Jenkins, Mark A., Kench, James G., Laaksonen, Maarit A., Leggett, Barbara, Mitchell, Gillian, Morris, Susan, Parkinson, Bonny, St John, D James ... Canfell, Karen (2020). Pathways to a cancer-free future: a protocol for modelled evaluations to minimise the future burden of colorectal cancer in Australia. BMJ Open, 10 (6) e036475, e036475. doi: 10.1136/bmjopen-2019-036475 |
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2020 Journal Article APC mutation marks an aggressive subtype of BRAF mutant colorectal cancersFennell, Lochlan J., Kane, Alexandra, Liu, Cheng, McKeone, Diane, Fernando, Winnie, Su, Chang, Bond, Catherine, Jamieson, Saara, Dumenil, Troy, Patch, Ann-Marie, Kazakoff, Stephen H., Pearson, John V., Waddell, Nicola, Leggett, Barbara and Whitehall, Vicki L. J (2020). APC mutation marks an aggressive subtype of BRAF mutant colorectal cancers. Cancers, 12 (5) 1171, 1-26. doi: 10.3390/cancers12051171 |
