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2020 Journal Article Traditional serrated adenoma-like lesions in patients with inflammatory bowel disease:Miller, Gregory C., Liu, Cheng, Bettington, Mark L., Leggett, Barbara, Whitehall, Vicki L.J. and Rosty, Christophe (2020). Traditional serrated adenoma-like lesions in patients with inflammatory bowel disease:. Human Pathology, 97, 19-28. doi: 10.1016/j.humpath.2019.12.005 |
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2019 Journal Article BRAF V600E immunohistochemistry demonstrates that some sessile serrated lesions with adenomatous dysplasia may represent collision lesionsBettington, Mark, Liu, Cheng, Gill, Anthony, Walker, Neal, Leggett, Barbara, Whitehall, Vicki and Rosty, Christophe (2019). BRAF V600E immunohistochemistry demonstrates that some sessile serrated lesions with adenomatous dysplasia may represent collision lesions. Histopathology, 75 (1), 81-87. doi: 10.1111/his.13851 |
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2019 Journal Article DNA methylation changes that precede onset of dysplasia in advanced sessile serrated adenomasLiu, Cheng, Fennell, Lochlan J., Bettington, Mark L., Walker, Neal I., Dwine, Joel, Leggett, Barbara A. and Whitehall, Vicki L. J. (2019). DNA methylation changes that precede onset of dysplasia in advanced sessile serrated adenomas. Clinical Epigenetics, 11 (1) 90, 90. doi: 10.1186/s13148-019-0691-4 |
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2019 Journal Article Integrative genome-scale DNA methylation analysis of a large and unselected cohort reveals five distinct subtypes of colorectal adenocarcinomasFennell, Lochlan, Dumenil, Troy, Wockner, Leesa, Hartel, Gunter, Nones, Katia, Bond, Catherine, Borowsky, Jennifer, Liu, Cheng, McKeone, Diane, Bowdler, Lisa, Montgomery, Grant, Klein, Kerenaftali, Hoffmann, Isabell, Patch, Ann-Marie, Kazakoff, Stephen, Pearson, John, Waddell, Nicola, Wirapati, Pratyaksha, Lochhead, Paul, Imamura, Yu, Ogino, Shuji, Shao, Renfu, Tejpar, Sabine, Leggett, Barbara and Whitehall, Vicki (2019). Integrative genome-scale DNA methylation analysis of a large and unselected cohort reveals five distinct subtypes of colorectal adenocarcinomas. Cellular and Molecular Gastroenterology and Hepatology, 8 (2), 269-290. doi: 10.1016/j.jcmgh.2019.04.002 |
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2019 Journal Article Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesisLannagan, Tamsin R. M., Lee, Young K., Wang, Tongtong, Roper, Jatin, Bettington, Mark L., Fennell, Lochlan, Vrbanac, Laura, Jonavicius, Lisa, Somashekar, Roshini, Gieniec, Krystyna, Yang, Miao, Ng, Jia Q., Suzuki, Nobumi, Ichinose, Mari, Wright, Josephine A., Kobayashi, Hiroki, Putoczki, Tracey L., Hayakawa, Yoku, Leedham, Simon J., Abud, Helen E., Yilmaz, Omer H., Marker, Julie, Klebe, Sonja, Wirapati, Pratyaksha, Mukherjee, Siddhartha, Tejpar, Sabine, Leggett, Barbara A., Whitehall, Vicki L. J., Worthley, Daniel L. and Woods, Susan L. (2019). Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis. Gut, 68 (4), 684-692. doi: 10.1136/gutjnl-2017-315920 |
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2019 Journal Article Five‐year conditional survival for patients with hepatocellular carcinoma in Queensland, AustraliaValery, Patricia C., Baade, Peter A., Stuart, Katherine A., Leggett, Barbara A., Macdonald, Graeme A., Whiteman, David C., Crawford, Darrell H. and Clark, Paul J. (2019). Five‐year conditional survival for patients with hepatocellular carcinoma in Queensland, Australia. GastroHep, 1 (2), 61-69. doi: 10.1002/ygh2.327 |
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2018 Journal Article CpG island methylation in sessile serrated adenomas increases with age, indicating lower risk of malignancy in young patientsLiu, Cheng, Bettington, Mark L., Walker, Neal I., Dwine, Joel, Hartel, Gunter F., Leggett, Barbara A. and Whitehall, Vicki L. J. (2018). CpG island methylation in sessile serrated adenomas increases with age, indicating lower risk of malignancy in young patients. Gastroenterology, 155 (5), 1362-1365. doi: 10.1053/j.gastro.2018.07.012 |
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2018 Journal Article NGM282 for treatment of patients with primary biliary cholangitis: a multicenter, randomized, double blind placebo controlled trialMayo, Marlyn J., Wigg, Alan J., Leggett, Barbara A., Arnold, Hays, Thompson, Alexander J., Weltman, Martin, Carey, Elizabeth J., Muir, Andrew J., Ling, Lei, Rossi, Stephen J. and Depaoli, Alex M. (2018). NGM282 for treatment of patients with primary biliary cholangitis: a multicenter, randomized, double blind placebo controlled trial. Hepatology Communications, 2 (9), 1037-1050. doi: 10.1002/hep4.1209 |
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2018 Journal Article A morphological and molecular study of proposed early forms of the traditional serrated adenomaBettington, Mark, Rosty, Christophe, Whitehall, Vicki, Leggett, Barbara, McKeone, Diane, Pearson, Sally-Ann and Walker, Neal (2018). A morphological and molecular study of proposed early forms of the traditional serrated adenoma. Histopathology, 73 (6), 1023-1029. doi: 10.1111/his.13714 |
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2018 Journal Article Sessile serrated adenomas in young patients may have limited risk of malignant progressionBettington, Mark, Brown, Ian, Rosty, Christophe, Walker, Neal, Liu, Cheng, Croese, John, Rahman, Tony, Pearson, Sally-Ann, McKeone, Diane, Leggett, Barbara and Whitehall, Vicki (2018). Sessile serrated adenomas in young patients may have limited risk of malignant progression. Journal of Clinical Gastroenterology, 53 (3), 1-e116. doi: 10.1097/MCG.0000000000001014 |
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2018 Journal Article The role of APC in WNT pathway activation in serrated neoplasiaBorowsky, Jennifer, Dumenil, Troy, Bettington, Mark, Pearson, Sally-Ann, Bond, Catherine, Fennell, Lochlan, Liu, Cheng, McKeone, Diane, Rosty, Christophe, Brown, Ian, Walker, Neal, Leggett, Barbara and Whitehall, Vicki (2018). The role of APC in WNT pathway activation in serrated neoplasia. Modern Pathology, 31 (3), 495-504. doi: 10.1038/modpathol.2017.150 |
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2018 Journal Article Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasiaBond, Catherine E., Liu, Cheng, Kawamata, Futoshi, McKeone, Diane M., Fernando, Winnie, Jamieson, Saara, Pearson, Sally-Ann, Kane, Alexandra, Woods, Susan L., Lannagan, Tamsin R. M., Somashekar, Roshini, Lee, Young, Dumenil, Troy, Hartel, Gunter, Spring, Kevin J., Borowsky, Jennifer, Fennell, Lochlan, Bettington, Mark, Lee, Jason, Worthley, Daniel L., Leggett, Barbara A. and Whitehall, Vicki L. J. (2018). Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia. Epigenetics, 13 (1), 40-48. doi: 10.1080/15592294.2017.1411446 |
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2018 Journal Article MLH1-93 G/a polymorphism is associated with MLH1 promoter methylation and protein loss in dysplastic sessile serrated adenomas with BRAFV600E mutationFennell, Lochlan J., Jamieson, Saara, McKeone, Diane, Corish, Tracie, Rohdmann, Megan, Furner, Tori, Bettington, Mark, Liu, Cheng, Kawamata, Futoshi, Bond, Catherine, Van De Pols, Jolieke, Leggett, Barbara and Whitehall, Vicki (2018). MLH1-93 G/a polymorphism is associated with MLH1 promoter methylation and protein loss in dysplastic sessile serrated adenomas with BRAFV600E mutation. BMC Cancer, 18 (1) 35, 1-7. doi: 10.1186/s12885-017-3946-5 |
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2018 Journal Article Copy number profiles of paired primary and metastatic colorectal cancersKawamata, Futoshi, Patch, Ann-Marie, Nones, Katia, Bond, Catherine, McKeone, Diane, Pearson, Sally-Ann, Homma, Shigenori, Liu, Cheng, Fennell, Lochlan, Dumenil, Troy, Hartel, Gunter, Kobayasi, Nozomi, Yokoo, Hideki, Fukai, Moto, Nishihara, Hiroshi, Kamiyama, Toshiya, Burge, Matthew E., Karapetis, Christos S., Taketomi, Akinobu, Leggett, Barbara, Waddell, Nicola and Whitehall, Vicki (2018). Copy number profiles of paired primary and metastatic colorectal cancers. Oncotarget, 9 (3), 3394-3405. doi: 10.18632/oncotarget.23277 |
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2017 Journal Article Sessile serrated adenomas with dysplasia: morphological patterns and correlations with MLH1 immunohistochemistryLiu, Cheng, Walker, Neal I., Leggett, Barbara A., Whitehall, Vicki L. J., Bettington, Mark L. and Rosty, Christophe (2017). Sessile serrated adenomas with dysplasia: morphological patterns and correlations with MLH1 immunohistochemistry. Modern Pathology, 30 (12), 1728-1738. doi: 10.1038/modpathol.2017.92 |
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2017 Journal Article RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancersFennell, Lochlan J. , Clendenning, Mark, McKeone, Diane M. , Jamieson, Saara H., Balachandran, Samanthy, Borowsky, Jennifer, Liu, John, Kawamata, Futoshi, Bond, Catherine E., Rosty, Christophe, Burge, Matthew E., Buchanan, Daniel D., Leggett, Barbara A. and Whitehall, Vicki L. J. (2017). RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers. Familial Cancer, 17 (1), 1-7. doi: 10.1007/s10689-017-0003-0 |
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2017 Journal Article GNAS mutations are present in colorectal traditional serrated adenomas, serrated tubulovillous adenomas and serrated adenocarcinomas with adverse prognostic featuresLiu, Cheng, Mckeone, Diane M., Walker, Neal I., Bettington, Mark L., Leggett, Barbara A. and Whitehall, Vicki L. J. (2017). GNAS mutations are present in colorectal traditional serrated adenomas, serrated tubulovillous adenomas and serrated adenocarcinomas with adverse prognostic features. Histopathology, 70 (7), 1079-1088. doi: 10.1111/his.13180 |
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2017 Journal Article Whole-genome landscape of pancreatic neuroendocrine tumoursScarpa, Aldo, Chang, David K., Nones, Katia, Corbo, Vincenzo, Patch, Ann-Marie, Bailey, Peter, Lawlor, Rita T., Johns, Amber L., Miller, David K., Mafficini, Andrea, Rusev, Borislav, Scardoni, Maria, Antonello, Davide, Barbi, Stefano, Sikora, Katarzyna O., Cingarlini, Sara, Vicentini, Caterina, McKay, Skye, Quinn, Michael C.J., Bruxner, Timothy J.C., Christ, Angelika N., Harliwong, Ivon, Idrisoglu, Senel, McLean, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wilson, Peter J., Anderson, Matthew J., Fink, J. Lynn ... Grimmond, Sean M. (2017). Whole-genome landscape of pancreatic neuroendocrine tumours. Nature, 543 (7643), 65-71. doi: 10.1038/nature21063 |
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2017 Journal Article High prevalence of sessile serrated adenomas in contemporary outpatient colonoscopy practiceBettington, Mark, Walker, Neal, Rahman, Tony, Vandeleur, Ann, Whitehall, Vicki, Leggett, Barbara and Croese, John (2017). High prevalence of sessile serrated adenomas in contemporary outpatient colonoscopy practice. Internal Medicine Journal, 47 (3), 318-323. doi: 10.1111/imj.13329 |
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2017 Conference Publication Sessile serrated adenomas with dysplasia: morphological patterns and correlations with MLH1 immunohistochemistryLiu, C., Walker, N. I., Leggett, B. A., Whitehall, V. L. J., Bettington, M. L. and Rosty, C. (2017). Sessile serrated adenomas with dysplasia: morphological patterns and correlations with MLH1 immunohistochemistry. Gastroenterological Society of Australia Australian Gastroenterology Week Precision Medicine in Gastroenterology, Gold Coast, QLD Australia, 20-22 August 2017. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. |
