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2025 Journal Article Genome of venomous caterpillar Doratifera vulnerans reveals recruitment of immune peptides and their adaptation as pain-inducing toxinsGoudarzi, Mohaddeseh H., Robinson, Samuel D., Cardoso, Fernanda C., Suryamohan, Kushal, Lawrence, Nicole, Eagles, David A., Hoang, Huy N., Vetter, Irina, Fairlie, David P., Seshagiri, Somasekar, King, Glenn F. and Walker, Andrew A. (2025). Genome of venomous caterpillar Doratifera vulnerans reveals recruitment of immune peptides and their adaptation as pain-inducing toxins. Proceedings of the National Academy of Sciences, 122 (49) e2513640122, 1-11. doi: 10.1073/pnas.2513640122 |
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2025 Journal Article Venom peptides across Asian and American tarantulas utilize dual pharmacology to target activation and fast inactivation of voltage-gated sodium channelsNashikwala, Amatulla S., Kotapati, Charan, Eagles, David A., Lewis, Richard J. and Cardoso, Fernanda C. (2025). Venom peptides across Asian and American tarantulas utilize dual pharmacology to target activation and fast inactivation of voltage-gated sodium channels. Toxins, 17 (11) 561, 561. doi: 10.3390/toxins17110561 |
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2024 Journal Article Secondary structure propensities of the Ebola delta peptide E40 in solution and model membrane environmentsLi, Jiayu, Eagles, David A., Tucker, Isaac J., Pereira Schmidt, Anneka C. and Deplazes, Evelyne (2024). Secondary structure propensities of the Ebola delta peptide E40 in solution and model membrane environments. Biophysical Chemistry, 314 107318, 1-9. doi: 10.1016/j.bpc.2024.107318 |
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2024 Conference Publication In vitro evolution of cyclic peptide inhibitors of acid-sensing ion channel 1a for neuroprotective applications during strokeBiggs, Kimberley, Passioura, Toby, Eagles, David and King, Glenn (2024). In vitro evolution of cyclic peptide inhibitors of acid-sensing ion channel 1a for neuroprotective applications during stroke. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons. |
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2024 Conference Publication Development of an equipotent NaV1.1 and NaV1.7 inhibitor for the treatment of chronic visceral painEagles, David, King, Glenn, Cardoso, Fernanda, Muttenthaler, Markus and Brierley, Stuart (2024). Development of an equipotent NaV1.1 and NaV1.7 inhibitor for the treatment of chronic visceral pain. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25 - 29 August 2024. Hoboken, NJ, United States: Wiley. |
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2024 Conference Publication Mending achy-breaky hearts: cyclic peptide TL01 is an enhancer of cardiac intracellular protein-protein interactions and promotes heart contractilityRojas-Azofeifa, Daniela, Passioura, Toby, McMillen, Timothy, Cheesman, Elisabeth, Saez, Natalie, Chow, Jonathan, Eagles, David, Norman, Alexander, Perry, Matthew, Molenar, Peter, Regnier, Michael, King, Glenn and Palpant, Nathan (2024). Mending achy-breaky hearts: cyclic peptide TL01 is an enhancer of cardiac intracellular protein-protein interactions and promotes heart contractility. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25-29 August 2024. Oxford, United Kingdom: John Wiley & Sons. |
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2023 Conference Publication Structure, function, and evolution of nettle caterpillar venom toxinsGoudarzi, Mohaddeseh H., Robinson, Samuel, Cardoso, Fernanda C., Lawrence, Nicole, Eagles, David, Chin, Y., King, Glenn F. and Walker, Andrew A. (2023). Structure, function, and evolution of nettle caterpillar venom toxins. V2D 2023: 8th Venoms to Drugs Conference, Moreton Island, QLD Australia, 9-13 October 2023. |
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2023 Journal Article Horizontal gene transfer underlies the painful stings of asp caterpillars (Lepidoptera: Megalopygidae)Walker, Andrew A., Robinson, Samuel D., Merritt, David J., Cardoso, Fernanda C., Goudarzi, Mohaddeseh Hedayati, Mercedes, Raine S., Eagles, David A., Cooper, Paul, Zdenek, Christina N., Fry, Bryan G., Hall, Donald W., Vetter, Irina and King, Glenn F. (2023). Horizontal gene transfer underlies the painful stings of asp caterpillars (Lepidoptera: Megalopygidae). Proceedings of the National Academy of Sciences, 120 (29) e2305871120, e2305871120. doi: 10.1073/pnas.2305871120 |
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2023 Journal Article Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae)Goudarzi, Mohaddeseh H., Eagles, David A., Lim, Junxian, Biggs, Kimberley A., Kotze, Andrew C., Ruffell, Angela P., Fairlie, David P., King, Glenn F. and Walker, Andrew A. (2023). Venom composition and bioactive RF-amide peptide toxins of the saddleback caterpillar, Acharia stimulea (Lepidoptera: Limacodidae). Biochemical Pharmacology, 213 115598, 1-11. doi: 10.1016/j.bcp.2023.115598 |
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2023 Journal Article The β3‐subunit modulates the effect of venom peptides ProTx‐II and OD1 on NaV 1.7 gatingSalvage, Samantha C., Rahman, Taufiq, Eagles, David A., Rees, Johanna S., King, Glenn F., Huang, Christopher L‐H. and Jackson, Antony P. (2023). The β3‐subunit modulates the effect of venom peptides ProTx‐II and OD1 on NaV 1.7 gating. Journal of Cellular Physiology, 238 (6), 1354-1367. doi: 10.1002/jcp.31018 |
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2022 Journal Article Cysteine-rich α-conotoxin SII displays novel interactions at the muscle nicotinic acetylcholine receptorWilhelm, Patrick, Luna-Ramirez, Karen, Chin, Yanni K.-Y., Dekan, Zoltan, Abraham, Nikita, Tae, Han-Shen, Chow, Chun Yuen, Eagles, David A., King, Glenn F., Lewis, Richard J., Adams, David J. and Alewood, Paul F. (2022). Cysteine-rich α-conotoxin SII displays novel interactions at the muscle nicotinic acetylcholine receptor. ACS Chemical Neuroscience, 13 (8), 1245-1250. doi: 10.1021/acschemneuro.1c00857 |
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2022 Journal Article A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammalsEagles, David A., Saez, Natalie J., Krishnarjuna, Bankala, Bradford, Julia J., Chin, Yanni K.-Y., Starobova, Hana, Mueller, Alexander, Reichelt, Melissa E., Undheim, Eivind A. B., Norton, Raymond S., Thomas, Walter G., Vetter, Irina, King, Glenn F. and Robinson, Samuel D. (2022). A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals. Proceedings of the National Academy of Sciences, 119 (7) e2112630119. doi: 10.1073/pnas.2112630119 |
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2020 Journal Article Fifteen years of NaV1.7 channels as an analgesic target: Why has excellent in vitro pharmacology not translated into in vivo analgesic efficacy?Eagles, David A., Chow, Chun Yuen and King, Glenn F. (2020). Fifteen years of NaV1.7 channels as an analgesic target: Why has excellent in vitro pharmacology not translated into in vivo analgesic efficacy?. British Journal of Pharmacology, 179 (14) bph.15327, 3592-3611. doi: 10.1111/bph.15327 |
