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2009

Journal Article

Cutaneous metabolism in transdermal drug delivery

Zhang, Qian, Grice, Jeffrey E., Wang, Guangji and Roberts, Michael S. (2009). Cutaneous metabolism in transdermal drug delivery. Current Drug Metabolism, 10 (3), 227-235. doi: 10.2174/138920009787846350

Cutaneous metabolism in transdermal drug delivery

2009

Journal Article

Diffusion modelling of percutaneous absorption kinetics: 4. Effects of a slow equilibration process within stratum corneum on absorption and desorption kinetics

Anissimov, Y. and Roberts, M. S. (2009). Diffusion modelling of percutaneous absorption kinetics: 4. Effects of a slow equilibration process within stratum corneum on absorption and desorption kinetics. Journal of Pharmaceutical Sciences, 98 (2), 772-781. doi: 10.1002/jps.21461

Diffusion modelling of percutaneous absorption kinetics: 4. Effects of a slow equilibration process within stratum corneum on absorption and desorption kinetics

2009

Journal Article

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Robertson, Thomas A., Dalley, Andrew J. and Lipman, Jeffrey (2009). Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution. Journal of Antimicrobial Chemotherapy, 64 (1), 142-150. doi: 10.1093/jac/dkp139

Meropenem dosing in critically ill patients with sepsis and without renal dysfunction: intermittent bolus versus continuous administration? Monte Carlo dosing simulations and subcutaneous tissue distribution

2009

Journal Article

Interventions that can reduce inappropriate prescribing in the elderly: A systematic review

Kaur, S., Mitchell, G., Vitetta, L. and Roberts, M.S. (2009). Interventions that can reduce inappropriate prescribing in the elderly: A systematic review. Drugs & Ageing, 26 (12), 1013-1028. doi: 10.2165/11318890-000000000-00000

Interventions that can reduce inappropriate prescribing in the elderly: A systematic review

2009

Journal Article

Computational strategies unravel and trace how liver disease changes hepatic drug disposition

Park, Sunwoo, Ropella, Glen E. P., Kim, Sean H. J., Roberts, Michael S. and Hunt, C. Anthony (2009). Computational strategies unravel and trace how liver disease changes hepatic drug disposition. Journal of Pharmacology and Experimental Therapeutics, 328 (1), 294-305. doi: 10.1124/jpet.108.142497

Computational strategies unravel and trace how liver disease changes hepatic drug disposition

2009

Journal Article

Assessment of Feasibility of Maillard Reaction between Baclofen and Lactose by Liquid Chromatography and Tandem Mass Spectrometry, Application to Pre Formulation Studies

Monajjemzadeh, F., Hassanzadeh, D., Valizadeh, H, Siahi-Shadbad, M. R., Mojarrad, J. S., Robertson, T. and Roberts, MS (2009). Assessment of Feasibility of Maillard Reaction between Baclofen and Lactose by Liquid Chromatography and Tandem Mass Spectrometry, Application to Pre Formulation Studies. AAPS PHARMSCITECH, 10 (2), 649-659. doi: 10.1208/s12249-009-9248-8

Assessment of Feasibility of Maillard Reaction between Baclofen and Lactose by Liquid Chromatography and Tandem Mass Spectrometry, Application to Pre Formulation Studies

2009

Journal Article

Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation

Cohen, Jeremy, Deans, Renae, Dalley, Andrew, Lipman, Jeff, Roberts, Michael S. and Venkatesh, Bala (2009). Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation. Critical Care, 13 (6) R189, xx-xx. doi: 10.1186/cc8184

Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation

2009

Journal Article

Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury

Dalley, Andrew J., Deans, Renae, Lipman, Jeffrey, Venkatesh, Bala, Rudd, Michael, Roberts, Michael S. and Cross, Sheree E. (2009). Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury. Antimicrobial Agents and Chemotherapy, 53 (12), 5303-5305. doi: 10.1128/AAC.01600-08

Unbound Cephalothin Pharmacokinetics in Adult Burn Patients Are Related to the Elapsed Time after Injury

2008

Journal Article

In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver

Roberts, Michael S., Roberts, Matthew J., Robertson, Thomas A., Sanchez, Washington, Thorling, Camilla, Zou, Yuhong, Zhao, Xin, Becker, Wolfgang and Zvyagin, Andrei V. (2008). In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver. Journal of Biophotonics, 1 (6), 478-493. doi: 10.1002/jbio.200810058

In vitro and in vivo imaging of xenobiotic transport in human skin and in the rat liver

2008

Journal Article

Quantitative Determination of Ophiopogonin D by Liquid Chromatography/Electrospray Ionization Mass Spectrometry and its Pharmacokinetics in Rat

Xai, Chun-hua, Sun, Jian-guo, Hao, Hai-ping, Wang, Guang-ji, Yan, Bei, Gu, Sheng-hua, Zheng, Chao-nan, Shang, Li-li and Roberts, Michael S. (2008). Quantitative Determination of Ophiopogonin D by Liquid Chromatography/Electrospray Ionization Mass Spectrometry and its Pharmacokinetics in Rat. Planta Medica, 74 (15), 1832-1836. doi: 10.1055/s-0028-1088339

Quantitative Determination of Ophiopogonin D by Liquid Chromatography/Electrospray Ionization Mass Spectrometry and its Pharmacokinetics in Rat

2008

Journal Article

Common skin conditions and disorders

Roberts, Michael S. (2008). Common skin conditions and disorders. Drug Discovery Today: Disease Mechanisms, 5 (2), 125-126. doi: 10.1016/j.ddmec.2008.09.008

Common skin conditions and disorders

2008

Journal Article

Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin

Weiss, Michael, Hung, Daniel Y., Poenicke, Klaus and Roberts, Michael S. (2008). Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin. European Journal of Pharmaceutical Sciences, 34 (4-5), 345-350. doi: 10.1016/j.ejps.2008.05.007

Kinetic analysis of saturable hepatic uptake of digoxin and its inhibition by rifampicin

2008

Journal Article

Use of in vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes

Cross, Sheree E. and Roberts, Michael S. (2008). Use of in vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes. Journal of Pharmaceutical Sciences, 97 (8), 3442-3450. doi: 10.1002/jps.21253

Use of in vitro human skin membranes to model and predict the effect of changing blood flow on the flux and retention of topically applied solutes

2008

Journal Article

Nanotechnology, cosmetics and the skin: Is there a health risk?

Nohynek, G. J., Dufour, E. K. and Roberts, M. S. (2008). Nanotechnology, cosmetics and the skin: Is there a health risk?. Skin Pharmacology & Physiology, 21 (3), 136-149. doi: 10.1159/000131078

Nanotechnology, cosmetics and the skin: Is there a health risk?

2008

Journal Article

Modelling and simulation of hepatic drug disposition using physiologically based, multi-agent in silico liver

Yan, Li, Ropella, Glen E. P., Park, Sunwoo, Roberts, Michael S. and Hunt, C. Anthony (2008). Modelling and simulation of hepatic drug disposition using physiologically based, multi-agent in silico liver. Pharmaceutical Research, 25 (5), 1023-1036. doi: 10.1007/s11095-007-9494-y

Modelling and simulation of hepatic drug disposition using physiologically based, multi-agent in silico liver

2008

Journal Article

Skin diseases

Roberts, Michael S. (2008). Skin diseases. Drug Discovery Today: Disease Mechanisms, 5 (1), e1-e2. doi: 10.1016/j.ddmec.2008.09.007

Skin diseases

2008

Journal Article

A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis

Roberts, Jason A., Roberts, Michael S., Robertson, Thomas A., Cross, Sheree E. and Lipman, Jeffrey (2008). A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis. International Journal of Antimicrobial Agents, 31 (3), 240-244. doi: 10.1016/j.ijantimicag.2007.09.013

A novel way to investigate the effects of plasma exchange on antibiotic levels: Use of microdialysis

2008

Journal Article

Skin biology, xerosis, barrier repair and measurement

Rawlings, A. V., Matts, P. J., Anderson, C. D. and Roberts, M. S. (2008). Skin biology, xerosis, barrier repair and measurement. Drug Discovery Today: Disease Mechanisms, 5 (2), e127-e136. doi: 10.1016/j.ddmec.2008.03.001

Skin biology, xerosis, barrier repair and measurement

2008

Journal Article

Non-melanoma skin cancers

Ahmed, A. H., Soyer, H. P., Saunders, N., Boukamp, P. and Roberts, M. S. (2008). Non-melanoma skin cancers. Drug Discovery Today: Disease Mechanisms, 5 (1), e55-e62. doi: 10.1016/j.ddmec.2008.05.007

Non-melanoma skin cancers

2008

Journal Article

Imaging of zinc oxide nanoparticle penetration in human skin in vitro and in vivo

Zvyagin, Andrei V., Zhao, Xin, Gierden, Audrey, Sanchez, Washington, Ross, Justin A. and Roberts, Michael. S. (2008). Imaging of zinc oxide nanoparticle penetration in human skin in vitro and in vivo. Journal of Biomedical Optics, 13 (6) 064031, 064031-1-064031-9. doi: 10.1117/1.3041492

Imaging of zinc oxide nanoparticle penetration in human skin in vitro and in vivo