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2026 Journal Article Trans-ancestry GWAS of hot flashes reveals potent treatment target and overlap with psychiatric disordersWerwath, Kathryn E., Lawn, Rebecca B., Salem, Madeleine T., Li, Tayden, Mitchell, Brittany L., Shen, Hanyang, Gordon, Scott D., Kung, Benson, Stafford, Ciera, Vemuri, Mytilee, Ratanatharathorn, Andrew, Meijsen, Joeri, Shadyab, Aladdin H., Kooperberg, Charles, Koenen, Karestan C., Crandall, Carolyn J., Martin, Nicholas G. and Duncan, Laramie E. (2026). Trans-ancestry GWAS of hot flashes reveals potent treatment target and overlap with psychiatric disorders. Communications Medicine, 6 (1) 51, 1-11. doi: 10.1038/s43856-025-01305-8 |
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2026 Journal Article Unravelling sex differences in the genetic architecture of anxietyHu, Jihua, Lupton, Michelle K., Byrne, Enda M., Martin, Nicholas G., Whiteman, David C., Olsen, Catherine M., Thomas, Jodi T., Medland, Sarah E., Grasby, Katrina L. and Mitchell, Brittany L. (2026). Unravelling sex differences in the genetic architecture of anxiety. Psychological Medicine, 56 e191, 1-12. doi: 10.1017/s0033291726104760 |
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2026 Journal Article Leisure activity engagement and depressive symptoms: meta-analysis of 11 studies of middle-aged and older twins aged 32-99Nygaard, Marianne, Mosing, Miriam A., Finkel, Deborah G., Franz, Carol E., Kremen, William S., Martin, Nicholas G., Plassman, Brenda L., Reynolds, Chandra A., Sachdev, Perminder S., Thalamuthu, Anbupalam, Walters, Ellen E., Christensen, Kaare, Pedersen, Nancy L., Gatz, Margaret, McGue, Matt and IGEMS Consortium (2026). Leisure activity engagement and depressive symptoms: meta-analysis of 11 studies of middle-aged and older twins aged 32-99. The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 81 (1) glaf253. doi: 10.1093/gerona/glaf253 |
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2026 Journal Article Genome-wide meta-analyses of non-response to antidepressants provide insights into underlying molecular genetics and suggest potential pharmacotherapiesKoch, Elise, Puusepp, Tuuli, Einarsson, Guðmundur, Mitchell, Brittany L., Harder, Arvid, Lin, Yuhao, García-Marín, Luis M., Krebs, Kristi, Shadrin, Alexey A., Xiong, Ying, Estonian Biobank Research Team, Metspalu, Andres, Esko, Tõnu, Mägi, Reedik, Nelis, Mari, Hudjashov, Georgi, Frei, Oleksandr, Lu, Yi, Hägg, Sara, Rentería, Miguel E., Medland, Sarah E., Wray, Naomi R., Martin, Nicholas G., Hübel, Christopher, Breen, Gerome, Thorgeirsson, Thorgeir, Stefánsson, Hreinn, Stefánsson, Kári, Lehto, Kelli ... O’Connell, Kevin S. (2026). Genome-wide meta-analyses of non-response to antidepressants provide insights into underlying molecular genetics and suggest potential pharmacotherapies. Molecular Psychiatry, 31 (4), 2005-2013. doi: 10.1038/s41380-025-03357-7 |
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2026 Journal Article Genetic and environmental effects on weight gain from young adulthood to old age and its association with body mass index in early young adulthood: an individual-based pooled analysis of 16 twin cohortsObeso, Alvaro, Drouard, Gabin, Jelenkovic, Aline, Ordoñana, Juan R., Sánchez-Romera, Juan F., Colodro-Conde, Lucía, Ollikainen, Miina, Aaltonen, Sari, Corley, Robin P., Huibregtse, Brooke M., Medda, Emanuela, Fagnani, Corrado, Toccaceli, Virgilia, Gatz, Margaret, Butler, David A., Bartels, Meike, Ligthart, Lannie, de Geus, Eco JC, Christensen, Kaare, Skytthe, Axel, Kyvik, Kirsten O., Medland, Sarah E., Gordon, Scott D., Rasmussen, Finn E., Tynelius, Per, Franz, Carol E., Kremen, William S., Lyons, Michael J., Spector, Timothy ... Silventoinen, Karri (2026). Genetic and environmental effects on weight gain from young adulthood to old age and its association with body mass index in early young adulthood: an individual-based pooled analysis of 16 twin cohorts. International Journal of Obesity, 50 (4), 768-776. doi: 10.1038/s41366-025-01998-w |
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2026 Journal Article The long reach of childhood income inequality: a multinational twin study of gene–environment interplay on adult depressive symptomsPetkus, Andrew J., Reynolds, Chandra A., Finch, Brian K., Thomas, Kyla, Beam, Christopher R., Catts, Vibeke S., Ericsson, Malin, Finkel, Deborah G., Franz, Carol E., Kremen, William S., Larsen, Lisbeth Aagaard, Martin, Nicholas G., McGue, Matt, Mosing, Miriam A., Neiderhiser, Jenae M., Nygaard, Marianne, Pedersen, Nancy L., Thalamuthu, Anbupalam, Whitfield, Keith E., Gatz, Margaret and the IGEMS Consortium (2026). The long reach of childhood income inequality: a multinational twin study of gene–environment interplay on adult depressive symptoms. Psychological Medicine, 56 e182, 1-10. doi: 10.1017/s0033291726104620 |
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2025 Journal Article Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic riskCurtis, Madeleine, Colodro‐Conde, Lucia, Medland, Sarah E., Gordon, Scott, Martin, Nicholas G., Wade, Tracey D. and Cohen‐Woods, Sarah (2025). Predicting adolescent disordered eating and behaviours: exploring environmental moderators of polygenic risk. Journal of Child Psychology and Psychiatry, 66 (12), 1795-1806. doi: 10.1111/jcpp.70012 |
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2025 Journal Article Unravelling the causal link between gut microbiota and acne risk using a genetic approachCao, Fangyuan, Ogonowski, Natalia S., Díaz-Torres, Santiago, Mitchell, Brittany L., Gharhakhani, Puya, Martin, Nicholas G., Simpson, Michael A., Ong, Jue-Sheng and Rentería, Miguel E. (2025). Unravelling the causal link between gut microbiota and acne risk using a genetic approach. Skin Health and Disease, 5 (6), 448-459. doi: 10.1093/skinhd/vzaf077 |
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2025 Journal Article Self-rated health and mortality: family background and genetic precursorsFinch, Brian Karl, Finkel, Deborah, Gatz, Margaret, Pedersen, Nancy L., Reynolds, Chandra A., Sachdev, Perminder, Selwood, Amanda, Martin, Nick and Mosing, Miriam A. (2025). Self-rated health and mortality: family background and genetic precursors. Discover Social Science and Health, 5 (1) 139. doi: 10.1007/s44155-025-00290-6 |
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2025 Journal Article Dyslexia polygenic index and socio-economic status interaction effects on reading skills in Australia and the United KingdomBicona, Diana, Mountford, Hayley S., Bridges, Elinor C., Fontanillas, Pierre, Martin, Nicholas G., Fisher, Simon E., Bates, Timothy C., Luciano, Michelle, 23andMe Research Team, Agee, Michelle, Aslibekyan, Stella, Auton, Adam, Babalola, Elizabeth, Bell, Robert K., Bielenberg, Jessica, Bryc, Katarzyna, Bullis, Emily, Cameron, Briana, Coker, Daniella, Partida, Gabriel Cuellar, Dhamija, Devika, Das, Sayantan, Elson, Sarah L., Filshtein, Teresa, Fletez-Brant, Kipper, Freyman, Will, Gandhi, Pooja M., Heilbron, Karl, Hicks, Barry ... Wilton, Peter (2025). Dyslexia polygenic index and socio-economic status interaction effects on reading skills in Australia and the United Kingdom. Behavior Genetics, 55 (5), 395-406. doi: 10.1007/s10519-025-10230-4 |
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2025 Journal Article Genetic overlap between DSM-IV major depressive disorder and suicidal behaviors: evidence from polygenic risk scores in young adult twinsGillespie, Nathan A., Su, Mei-Hsin, Lannoy, Séverine, Stephenson, Mallory, Rentería, Miguel E., Ceja, Zuriel, Hickie, Ian B., Martin, Nicholas G. and Edwards, Alexis C. (2025). Genetic overlap between DSM-IV major depressive disorder and suicidal behaviors: evidence from polygenic risk scores in young adult twins. Behavior Genetics, 55 (6), 423-437. doi: 10.1007/s10519-025-10234-0 |
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2025 Journal Article Life without sex: large-scale study links sexlessness to physical, cognitive, and personality traits, socioecological factors, and DNAAbdellaoui, Abdel, Wesseldijk, Laura W., Gordon, Scott D., Pasman, Joëlle A., Smit, Dirk J. A., Androvičová, Renáta, Martin, Nicholas G., Ullén, Fredrik, Mosing, Miriam A., Zietsch, Brendan P. and Verweij, Karin J. H. (2025). Life without sex: large-scale study links sexlessness to physical, cognitive, and personality traits, socioecological factors, and DNA. Proceedings of the National Academy of Sciences, 122 (38) e2418257122, 1-12. doi: 10.1073/pnas.2418257122 |
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2025 Journal Article Sex-stratified genome-wide association meta-analysis of major depressive disorderThomas, Jodi T., Thorp, Jackson G., Huider, Floris, Grimes, Poppy Z., Wang, Rujia, Youssef, Pierre, Coleman, Jonathan R. I., Byrne, Enda M., Adams, Mark, BIONIC consortium, van Loo, Hanna M., Penninx, Brenda W. J. H., The GLAD Study, Medland, Sarah E., Hickie, Ian B., Olsen, Catherine M., Whiteman, David C., Whalley, Heather C., Penninx, Brenda W.J.H., van Loo, Hanna M., Derks, Eske M., Eley, Thalia C., Breen, Gerome, Boomsma, Dorret I., Wray, Naomi R., Martin, Nicholas G. and Mitchell, Brittany L. (2025). Sex-stratified genome-wide association meta-analysis of major depressive disorder. Nature Communications, 16 (1) 7960, 1-15. doi: 10.1038/s41467-025-63236-1 |
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2025 Journal Article Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smokingHe, Weixiong, van der Most, Peter J., Ong, Jue-Sheng, Hwang, Liang-Dar, Wu, Yeda, Magnø, Morten S., Vehof, Jelle, Krebs, Kristi, Mauring, Laura, Õunap, Katrin, Abner, Erik, Martin, Nicholas G., Plotnikov, Denis, Jiang, Chen, Melles, Ronald B., Gharahkhani, Puya, Snieder, Harold, Palumaa, Teele, Kaljurand, Kuldar, Guggenheim, Jeremy A., Mackey, David A., Engle, Elizabeth C., Choquet, Hélène, MacGregor, Stuart, Lifelines Cohort Study, Aguirre-Gamboa, Raul, Deelen, Patrick, Franke, Lude, Kuivenhoven, Jan A. ... Wray, Naomi (2025). Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking. Nature Communications, 16 (1) 7890, 1-14. doi: 10.1038/s41467-025-62456-9 |
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2025 Journal Article Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traitsJohnson, Emma C., Lai, Dongbing, Balbona, Jared V., Miller, Alex P., Hatoum, Alexander S., Deak, Joseph D., Jennings, Mariela, Baranger, David A. A., Galimberti, Marco, Sanichwankul, Kittipong, Thorgeirsson, Thorgeir, Colbert, Sarah M. C., Adhikari, Keyrun, Docherty, Anna R., Degenhardt, Louisa, Edwards, Tobias, Fox, Louis, Giannelis, Alexandros, Jeffries, Paul W., Korhonen, Tellervo, Morrison, Claire L., Nunez, Yaira Z., Palviainen, Teemu, Su, Mei-Hsin, Romero Villela, Pamela N., Wetherill, Leah, Willoughby, Emily A., Zellers, Stephanie M., Bierut, Laura J. ... Agrawal, Arpana (2025). Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. Psychological Medicine, 55 e234, e234. doi: 10.1017/S0033291725100883 |
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2025 Journal Article Multivariate genome-wide association analysis of dyslexia and quantitative reading skill improves gene discoveryMountford, Hayley S., Eising, Else, Fontanillas, Pierre, Auton, Adam, 23andMe Research Team, Aslibekyan, Stella, Bell, Robert K., Kukar Bond, Katelyn, Cochinwala, Zayn, Das, Sayantan, de Brito, Kahsaia, DelloRusso, Emily, Eijsbouts, Chris, Elson, Sarah L., German, Chris, Granka, Julie M., Hicks, Barry, Hinds, David A., Jabal, Reza, Khan, Aly, Kmiecik, Matthew J., Kwong, Alan, Liang, Yanyu, Lin, Keng-Han, McIntyre, Matthew H., Saini, Shubham, Shastri, Anjali J., Shi, Jingchunzi, Shringarpure, Suyash ... Luciano, Michelle (2025). Multivariate genome-wide association analysis of dyslexia and quantitative reading skill improves gene discovery. Translational Psychiatry, 15 (1) 289, 1-19. doi: 10.1038/s41398-025-03514-0 |
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2025 Journal Article Uncovering the multivariate genetic architecture of frailty with genomic structural equation modelingFoote, Isabelle F., Flint, Jonny P., Fürtjes, Anna E., Lawrence, Jeremy M., Mullin, Donncha S., Fisk, John D., Karakach, Tobias K., Rutenberg, Andrew, Martin, Nicholas G., Lupton, Michelle K., Llewellyn, David J., Ranson, Janice M., Cox, Simon R., Luciano, Michelle, Rockwood, Kenneth and Grotzinger, Andrew D. (2025). Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling. Nature Genetics, 57 (8), 1848-1859. doi: 10.1038/s41588-025-02269-0 |
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2025 Journal Article Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypesAssary, Elham, Coleman, Jonathan R. I., Hemani, Gibran, van de Weijer, Margot P., Howe, Laurence J., Palviainen, Teemu, Grasby, Katrina L., Ahlskog, Rafael, Nygaard, Marianne, Cheesman, Rosa, Lim, Kai, Reynolds, Chandra A., Ordoñana, Juan R., Colodro-Conde, Lucia, Gordon, Scott, Madrid-Valero, Juan J., Thalamuthu, Anbupalam, Hottenga, Jouke-Jan, Mengel-From, Jonas, Armstrong, Nicola J., Sachdev, Perminder S., Lee, Teresa, Brodaty, Henry, Trollor, Julian N., Wright, Margaret, Ames, David, Catts, Vibeke S., Latvala, Antti, The Within Family Consortium ... Keers, Robert (2025). Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes. Nature Human Behaviour, 9 (8), 1683-1696. doi: 10.1038/s41562-025-02193-7 |
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2025 Journal Article Exploring the relationship between polygenic scores, community-shared socioeconomic indicators and major depressive disorder outcomeSepulveda, Dante T., Thorp, Jackson G., Lind, Penelope A., Martin, Nicholas G., Medland, Sarah E. and Mitchell, Brittany L. (2025). Exploring the relationship between polygenic scores, community-shared socioeconomic indicators and major depressive disorder outcome. Twin Research and Human Genetics, 28 (3), 241-249. doi: 10.1017/thg.2025.10011 |
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2025 Journal Article Fine-mapping genomic loci refines bipolar disorder risk genesKoromina, Maria, Ravi, Ashvin, Panagiotaropoulou, Georgia, Schilder, Brian M., Humphrey, Jack, Braun, Alice, Bidgeli, Tim, Chatzinakos, Chris, Coombes, Brandon J., Kim, Jaeyoung, Liu, Xiaoxi, Terao, Chikashi, O’Connell, Kevin S., Adams, Mark J., Adolfsson, Rolf, Alda, Martin, Alfredsson, Lars, Andlauer, Till F. M., Andreassen, Ole A., Antoniou, Anastasia, Baune, Bernhard T., Bengesser, Susanne, Biernacka, Joanna, Boehnke, Michael, Bosch, Rosa, Cairns, Murray J., Carr, Vaughan J., Casas, Miquel, Catts, Stanley ... Mullins, Niamh (2025). Fine-mapping genomic loci refines bipolar disorder risk genes. Nature Neuroscience, 28 (7), 1393-1403. doi: 10.1038/s41593-025-01998-z |
