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2021

Journal Article

Genetic association study of childhood aggression across raters, instruments, and age

Ip, Hill F., van der Laan, Camiel M., Krapohl, Eva M. L., Brikell, Isabell, Sánchez-Mora, Cristina, Nolte, Ilja M., St Pourcain, Beate, Bolhuis, Koen, Palviainen, Teemu, Zafarmand, Hadi, Colodro-Conde, Lucía, Gordon, Scott, Zayats, Tetyana, Aliev, Fazil, Jiang, Chang, Wang, Carol A., Saunders, Gretchen, Karhunen, Ville, Hammerschlag, Anke R., Adkins, Daniel E., Border, Richard, Peterson, Roseann E., Prinz, Joseph A., Thiering, Elisabeth, Seppälä, Ilkka, Vilor-Tejedor, Natàlia, Ahluwalia, Tarunveer S., Day, Felix R., Hottenga, Jouke-Jan ... Boomsma, Dorret I. (2021). Genetic association study of childhood aggression across raters, instruments, and age. Translational Psychiatry, 11 (1) 413, 413. doi: 10.1038/s41398-021-01480-x

Genetic association study of childhood aggression across raters, instruments, and age

2021

Journal Article

Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype

Campos, Adrián I., Ngo, Trung Thanh, Medland, Sarah E., Wray, Naomi R., Hickie, Ian B., Byrne, Enda M., Martin, Nicholas G. and Rentería, Miguel E. (2021). Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype. Australian and New Zealand Journal of Psychiatry, 56 (9) 00048674211031491, 1-10. doi: 10.1177/00048674211031491

Genetic risk for chronic pain is associated with lower antidepressant effectiveness: converging evidence for a depression subtype

2021

Journal Article

Ethnic Identity and Genome Wide Runs of Homozygosity

Fieder, Martin, Mitchell, Brittany L., Gordon, Scott, Huber, Susanne and Martin, Nicholas G. (2021). Ethnic Identity and Genome Wide Runs of Homozygosity. Behavior Genetics, 51 (4), 405-413. doi: 10.1007/s10519-021-10053-z

Ethnic Identity and Genome Wide Runs of Homozygosity

2021

Journal Article

Using monozygotic twins to dissect common genes in posttraumatic stress disorder and migraine

Bainomugisa, Charlotte K., Sutherland, Heidi G., Parker, Richard, Mcrae, Allan F., Haupt, Larisa M., Griffiths, Lyn R., Heath, Andrew, Nelson, Elliot C., Wright, Margaret J., Hickie, Ian B., Martin, Nicholas G., Nyholt, Dale R. and Mehta, Divya (2021). Using monozygotic twins to dissect common genes in posttraumatic stress disorder and migraine. Frontiers in Neuroscience, 15 678350, 678350. doi: 10.3389/fnins.2021.678350

Using monozygotic twins to dissect common genes in posttraumatic stress disorder and migraine

2021

Journal Article

Early expressions of psychopathology and risk associated with trans-diagnostic transition to mood and psychotic disorders in adolescents and young adults

Scott, Jan, Crouse, Jacob J., Ho, Nicholas, Iorfino, Frank, Martin, Nicholas, Parker, Richard, McGrath, John, Gillespie, Nathan A., Medland, Sarah and Hickie, Ian B. (2021). Early expressions of psychopathology and risk associated with trans-diagnostic transition to mood and psychotic disorders in adolescents and young adults. PLoS ONE, 16 (6 June) e0252550, 1-17. doi: 10.1371/journal.pone.0252550

Early expressions of psychopathology and risk associated with trans-diagnostic transition to mood and psychotic disorders in adolescents and young adults

2021

Journal Article

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Mullins, Niamh, Forstner, Andreas J., O'Connell, Kevin S., Coombes, Brandon, Coleman, Jonathan R I, Qiao, Zhen, Als, Thomas D., Bigdeli, Tim B., Børte, Sigrid, Bryois, Julien, Charney, Alexander W., Drange, Ole Kristian, Gandal, Michael J., Hagenaars, Saskia P., Ikeda, Masashi, Kamitaki, Nolan, Kim, Minsoo, Krebs, Kristi, Panagiotaropoulou, Georgia, Schilder, Brian M., Sloofman, Laura G., Steinberg, Stacy, Trubetskoy, Vassily, Winsvold, Bendik S., Won, Hong-Hee, Abramova, Liliya, Adorjan, Kristina, Agerbo, Esben, Al Eissa, Mariam ... Andreassen, Ole A. (2021). Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature genetics, 53 (6), 817-829. doi: 10.1038/s41588-021-00857-4

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

2021

Journal Article

Phenome-wide screening of GWAS data reveals the complex causal architecture of obesity

García-Marín, Luis M., Campos, Adrián I., Kho, Pik-Fang, Martin, Nicholas G., Cuéllar-Partida, Gabriel and Rentería, Miguel E. (2021). Phenome-wide screening of GWAS data reveals the complex causal architecture of obesity. Human Genetics, 140 (8), 1253-1265. doi: 10.1007/s00439-021-02298-9

Phenome-wide screening of GWAS data reveals the complex causal architecture of obesity

2021

Journal Article

Correction to: The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption

Hwang, Liang-Dar, Mitchell, Brittany L., Medland, Sarah E., Martin, Nicholas G., Neale, Michael C. and Evans, David M. (2021). Correction to: The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption. Behavior Genetics, 51 (4), 441-442. doi: 10.1007/s10519-021-10065-9

Correction to: The augmented Classical Twin Design: incorporating genome‐wide identity by descent sharing into twin studies in order to model violations of the equal environments assumption

2021

Journal Article

Days out of role and somatic, anxious-depressive, hypo-manic, and psychotic-like symptom dimensions in a community sample of young adults

Crouse, Jacob J., Ho, Nicholas, Scott, Jan, Martin, Nicholas G., Couvy-Duchesne, Baptiste, Hermens, Daniel F., Parker, Richard, Gillespie, Nathan A., Medland, Sarah E. and Hickie, Ian B. (2021). Days out of role and somatic, anxious-depressive, hypo-manic, and psychotic-like symptom dimensions in a community sample of young adults. Translational Psychiatry, 11 (1) 285, 285. doi: 10.1038/s41398-021-01390-y

Days out of role and somatic, anxious-depressive, hypo-manic, and psychotic-like symptom dimensions in a community sample of young adults

2021

Journal Article

The association between genetically determined ABO blood types and major depressive disorder

Garvert, Linda, Baune, Bernhard T, Berger, Klaus, Boomsma, Dorret I, Breen, Gerome, Greinacher, Andreas, Hamilton, Steven P, Levinson, Douglas F, Lewis, Cathryn M, Lucae, Susanne, Magnusson, Patrik K E, Martin, Nicholas G, McIntosh, Andrew M, Mors, Ole, Müller-Myhsok, Bertram, Penninx, Brenda W J H, Perlis, Roy H, Pistis, Giorgio, Potash, James B, Preisig, Martin, Rietschel, Marcella, Shi, Jianxin, Smoller, Jordan W, Tiemeier, Henning, Uher, Rudolf, Völker, Uwe, Völzke, Henry, Weissman, Myrna M, Grabe, Hans J and Van der Auwera, Sandra (2021). The association between genetically determined ABO blood types and major depressive disorder. Psychiatry Research, 299 113837, 113837. doi: 10.1016/j.psychres.2021.113837

The association between genetically determined ABO blood types and major depressive disorder

2021

Journal Article

Typologies of illicit drug use in mid-adulthood: a quasi-longitudinal latent class analysis in a community-based sample of twins

Dash, Genevieve F., Martin, Nicholas G., Agrawal, Arpana, Lynskey, Michael T. and Slutske, Wendy S. (2021). Typologies of illicit drug use in mid-adulthood: a quasi-longitudinal latent class analysis in a community-based sample of twins. Addiction, 116 (5), 1101-1112. doi: 10.1111/add.15225

Typologies of illicit drug use in mid-adulthood: a quasi-longitudinal latent class analysis in a community-based sample of twins

2021

Journal Article

Epigenome-wide association study of thyroid function traits identifies novel associations of fT3 with KLF9 and DOT1L

Lafontaine, Nicole, Campbell, Purdey J., Castillo-Fernandez, Juan E., Mullin, Shelby, Lim, Ee Mun, Kendrew, Phillip, Lewer, Michelle, Brown, Suzanne J., Huang, Rae-Chi, Melton, Phillip E., Mori, Trevor A., Beilin, Lawrence J., Dudbridge, Frank, Spector, Tim D., Wright, Margaret J., Martin, Nicholas G., McRae, Allan F., Panicker, Vijay, Zhu, Gu, Walsh, John P., Bell, Jordana T. and Wilson, Scott G. (2021). Epigenome-wide association study of thyroid function traits identifies novel associations of fT3 with KLF9 and DOT1L. The Journal of Clinical Endocrinology and Metabolism, 106 (5), e2191-e2202. doi: 10.1210/clinem/dgaa975

Epigenome-wide association study of thyroid function traits identifies novel associations of fT3 with KLF9 and DOT1L

2021

Journal Article

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression

Thorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary F., An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M. and Derks, Eske M. (2021). Symptom-level modelling unravels the shared genetic architecture of anxiety and depression. Nature Human Behaviour, 5 (10), 1432-1442. doi: 10.1038/s41562-021-01094-9

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression

2021

Journal Article

Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness

Roughan, William H., Campos, Adrián I., García-Marín, Luis M., Cuéllar-Partida, Gabriel, Lupton, Michelle K., Hickie, Ian B., Medland, Sarah E., Wray, Naomi R., Byrne, Enda M., Ngo, Trung Thanh, Martin, Nicholas G. and Rentería, Miguel E. (2021). Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness. Frontiers in Psychiatry, 12 643609, 1-13. doi: 10.3389/fpsyt.2021.643609

Comorbid chronic pain and depression: shared risk factors and differential antidepressant effectiveness

2021

Journal Article

'Essential Tremor' Phenotype in FMR1 Premutation/Gray Zone Sibling Series: Exploring Possible Genetic Modifiers

Loesch, Danuta Z., Duffy, David L., Martin, Nicholas G., Tassone, Flora, Atkinson, Anna and Storey, Elsdon (2021). 'Essential Tremor' Phenotype in FMR1 Premutation/Gray Zone Sibling Series: Exploring Possible Genetic Modifiers. Twin Research and Human Genetics, 24 (2), 95-102. doi: 10.1017/thg.2021.10

'Essential Tremor' Phenotype in FMR1 Premutation/Gray Zone Sibling Series: Exploring Possible Genetic Modifiers

2021

Journal Article

Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color

Simcoe, Mark, Valdes, Ana, Liu, Fan, Furlotte, Nicholas A., Evans, David M., Hemani, Gibran, Ring, Susan M., Smith, George Davey, Duffy, David L., Zhu, Gu, Gordon, Scott D., Medland, Sarah E., Vuckovic, Dragana, Girotto, Giorgia, Sala, Cinzia, Catamo, Eulalia, Concas, Maria Pina, Brumat, Marco, Gasparini, Paolo, Toniolo, Daniela, Cocca, Massimiliano, Robino, Antonietta, Yazar, Seyhan, Hewitt, Alex, Wu, Wenting, Kraft, Peter, Hammond, Christopher J., Shi, Yuan, Chen, Yan ... the International Visible Trait Genetics Consortium (2021). Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color. Science Advances, 7 (11) abd1239, eabd1239. doi: 10.1126/sciadv.abd1239

Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color

2021

Journal Article

Brain correlates of suicide attempt in 18,925 participants across 18 international cohorts

Campos, Adrian I., Thompson, Paul M., Veltman, Dick J., Pozzi, Elena, van Veltzen, Laura S., Jahanshad, Neda, Adams, Mark J., Baune, Bernhard T., Berger, Klaus, Brosch, Katharina, Bülow, Robin, Connolly, Colm G., Dannlowski, Udo, Davey, Christopher G., de Zubicaray, Greig I., Dima, Danai, Erwin-Grabner, Tracy, Evans, Jennifer W., Fu, Cynthia H.Y., Gotlib, Ian H., Goya-Maldonado, Roberto, Grabe, Hans J., Grotegerd, Dominik, Harris, Matthew A., Harrison, Ben J., Hatton, Sean N., Hermesdorf, Marco, Hickie, Ian B., Ho, Tiffany C. ... Rentería, Miguel E. (2021). Brain correlates of suicide attempt in 18,925 participants across 18 international cohorts. Biological Psychiatry, 90 (4), 243-252. doi: 10.1016/j.biopsych.2021.03.015

Brain correlates of suicide attempt in 18,925 participants across 18 international cohorts

2021

Journal Article

Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes

Sherva, Richard, Zhu, Congcong, Wetherill, Leah, Edenberg, Howard J., Johnson, Emma, Degenhardt, Louisa, Agrawal, Arpana, Martin, Nicholas G., Nelson, Elliot, Kranzler, Henry R., Gelernter, Joel and Farrer, Lindsay A. (2021). Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. Exploration of Medicine, 2 (1), 60-73. doi: 10.37349/emed.2021.00032

Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes

2021

Journal Article

Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?

Scott, Jan, Crouse, Jacob J., Ho, Nicholas, Carpenter, Joanne, Martin, Nicholas, Medland, Sarah, Parker, Richard, Byrne, Enda, Couvy-Duchesne, Baptiste, Mitchell, Brittany, Merikangas, Kathleen, Gillespie, Nathan A. and Hickie, Ian (2021). Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?. Bipolar Disorders, 23 (6), 584-594. doi: 10.1111/bdi.13067

Can network analysis of self-reported psychopathology shed light on the core phenomenology of bipolar disorders in adolescents and young adults?

2021

Journal Article

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

Gharahkhani, Puya, NEIGHBORHOOD consortium, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P., Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W., Segrè, Ayellet V., Rouhana, John M., Hamel, Andrew R., Igo, Robert P., Choquet, Helene, Qassim, Ayub, Josyula, Navya S., Cooke Bailey, Jessica N., Bonnemaijer, Pieter W. M., Iglesias, Adriana, Siggs, Owen M., Young, Terri L., Vitart, Veronique, Thiadens, Alberta A. H. J., Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B., Nair, K. Saidas, Luben, Robert, Simcoe, Mark ... 23 and Me Research Team (2021). Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. Nature Communications, 12 (1) 1258, 1-16. doi: 10.1038/s41467-020-20851-4

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries