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2016

Conference Publication

An assessment of the utility of DNA barcoding in the quality control of herbal raw materials, extracts and finished products

Wohlmuth, H., Leach, D., McGrath, K., Gordon, L., Mouatt, P. and De Voss, J. (2016). An assessment of the utility of DNA barcoding in the quality control of herbal raw materials, extracts and finished products. 9th Joint Meeting of AFERP, ASP, GA, JSP, PSE and SIF, Copenhagen, Denmark, 24 - 27 July 2016. Stuttgart, Germany: Georg Thieme Verlag. doi: 10.1055/s-0036-1597032

An assessment of the utility of DNA barcoding in the quality control of herbal raw materials, extracts and finished products

2015

Journal Article

Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa

Challinor, Victoria L., Johnston, Ryne C., Bernhardt, Paul V., Lehmann, Reginald P., Krenske, Elizabeth H. and De Voss, James J. (2015). Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa. Chemical Science, 6 (10), 5740-5745. doi: 10.1039/c5sc02056e

Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa

2015

Journal Article

CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivatives

Coleman, Tom, Chao, Rebecca R., Bruning, John B., De Voss, James J. and Bell, Stephen G. (2015). CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivatives. RSC Advances, 5 (64), 52007-52018. doi: 10.1039/c5ra08730a

CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivatives

2015

Book Chapter

Cytochrome P450cin (CYP176A1)

Stok, Jeanette E., Slessor, Kate E., Farlow, Anthony J., Hawkes, David B. and De Voss, James J. (2015). Cytochrome P450cin (CYP176A1). Monooxygenase, Peroxidase and Peroxygenase Properties and Mechanisms of Cytochrome P450. (pp. 319-339) edited by Eugene G. Hrycay and Stelvio M. Bandiera. New York, NY United States: Springer New York LLC. doi: 10.1007/978-3-319-16009-2_12

Cytochrome P450cin (CYP176A1)

2014

Journal Article

Electrochemically mediated enantioselective reduction of chiral sulfoxides

Chen, Kuan I., Challinor, Victoria L., Kielmann, Linda, Sharpe, Philip C., De Voss, James J., Kappler, Ulrike, McEwan, Alastair G. and Bernhardt, Paul V. (2014). Electrochemically mediated enantioselective reduction of chiral sulfoxides. Journal of Biological Inorganic Chemistry, 20 (2), 395-402. doi: 10.1007/s00775-014-1215-5

Electrochemically mediated enantioselective reduction of chiral sulfoxides

2014

Journal Article

Oxidative carbon-carbon bond cleavage is a key step in spiroacetal biosynthesis in the fruit fly Bactrocera cacuminata

Singh, Arti A., Rowley, Jessica A., Schwartz, Brett D., Kitching, William and De Voss, James J. (2014). Oxidative carbon-carbon bond cleavage is a key step in spiroacetal biosynthesis in the fruit fly Bactrocera cacuminata. Journal of Organic Chemistry, 79 (17), 7799-7821. doi: 10.1021/jo500791y

Oxidative carbon-carbon bond cleavage is a key step in spiroacetal biosynthesis in the fruit fly Bactrocera cacuminata

2014

Journal Article

Structural and mechanistic insight into alkane hydroxylation by Pseudomonas putida AlkB

Alonso, Hernan, Kleifeld, Oded, Yeheskel, Adva, Ong, Poh C., Liu, Yu C., Stok, Jeanette E., De Voss, James J. and Roujeinikova, Anna (2014). Structural and mechanistic insight into alkane hydroxylation by Pseudomonas putida AlkB. Biochemical Journal, 460 (2), 283-293. doi: 10.1042/BJ20131648

Structural and mechanistic insight into alkane hydroxylation by Pseudomonas putida AlkB

2014

Journal Article

Carbon-Carbon bond cleavage in activation of the prodrug nabumetone

Varfaj, Fatbardha, Zulkifli, Siti N. A., Park, Hyoung-Goo, Challinor, Victoria L., De Voss, James J. and De Montellano, Paul R. Ortiz (2014). Carbon-Carbon bond cleavage in activation of the prodrug nabumetone. Drug Metabolism and Disposition, 42 (5), 828-838. doi: 10.1124/dmd.114.056903

Carbon-Carbon bond cleavage in activation of the prodrug nabumetone

2013

Journal Article

Synthesis and determination of the absolute configuration of (-)-(5R,6Z)-dendrolasin-5-acetate from the nudibranch Hypselodoris jacksoni

Mudianta, I. Wayan, Challinor, Victoria L., Winters, Anne E., Cheney, Karen L., De Voss, James J. and Garson, Mary J. (2013). Synthesis and determination of the absolute configuration of (-)-(5R,6Z)-dendrolasin-5-acetate from the nudibranch Hypselodoris jacksoni. Beilstein Journal of Organic Chemistry, 9 (1), 2925-2933. doi: 10.3762/bjoc.9.329

Synthesis and determination of the absolute configuration of (-)-(5R,6Z)-dendrolasin-5-acetate from the nudibranch Hypselodoris jacksoni

2013

Journal Article

Structure and absolute configuration of methyl (3R)-malonyl-(13S)-hydroxycheilanth-17-en-19-oate, a sesterterpene derivative from the roots of Aletris farinosa

Challinor, Victoria L., Chap, Sonet, Lehmann, Reginald P., Bernhardt, Paul V. and De Voss, James J. (2013). Structure and absolute configuration of methyl (3R)-malonyl-(13S)-hydroxycheilanth-17-en-19-oate, a sesterterpene derivative from the roots of Aletris farinosa. Journal of Natural Products, 76 (4), 485-488. doi: 10.1021/np400035n

Structure and absolute configuration of methyl (3R)-malonyl-(13S)-hydroxycheilanth-17-en-19-oate, a sesterterpene derivative from the roots of Aletris farinosa

2013

Journal Article

Synthesis of oxygenated cineole derivatives from cineole: utility of cytochrome P450(cin) as an enantioselective catalyst

Farlow, Anthony J., Bernhardt, Paul V. and De Voss, James J. (2013). Synthesis of oxygenated cineole derivatives from cineole: utility of cytochrome P450(cin) as an enantioselective catalyst. Tetrahedron: Asymmetry, 24 (5-6), 324-333. doi: 10.1016/j.tetasy.2013.02.004

Synthesis of oxygenated cineole derivatives from cineole: utility of cytochrome P450(cin) as an enantioselective catalyst

2013

Journal Article

Cytochrome P450(cin) (CYP176A1) D241N: investigating the role of the conserved acid in the active site of cytochrome P450s

Stok, Jeanette E., Yamada, Sean, Farlow, Anthony J., Slessor, Kate E. and De Voss, James J. (2013). Cytochrome P450(cin) (CYP176A1) D241N: investigating the role of the conserved acid in the active site of cytochrome P450s. Biochimica et Biophysica Acta: Proteins and Proteomics, 1834 (3), 688-696. doi: 10.1016/j.bbapap.2012.12.022

Cytochrome P450(cin) (CYP176A1) D241N: investigating the role of the conserved acid in the active site of cytochrome P450s

2013

Journal Article

Open-chain steroidal glycosides, a diverse class of plant saponins

Challinor, Victoria L. and De Voss, James J. (2013). Open-chain steroidal glycosides, a diverse class of plant saponins. Natural Product Reports, 30 (3), 429-454. doi: 10.1039/c3np20105h

Open-chain steroidal glycosides, a diverse class of plant saponins

2013

Book Chapter

Plant steroidal saponins: A focus on open-chain glycosides

Challinor, Victoria L. and de Voss, James J. (2013). Plant steroidal saponins: A focus on open-chain glycosides. Natural Products: Phytochemistry, Botany and Metabolism of Alkaloids, Phenolics and Terpenes. (pp. 3225-3250) edited by Kishan Gopal Ramawat and Jean-Michel Mérillon. Berlin, Germany: Springer. doi: 10.1007/978-3-642-22144-6_139

Plant steroidal saponins: A focus on open-chain glycosides

2012

Journal Article

Enzyme-substrate complementarity governs access to a cationic reaction manifold in the P450(BM3) -catalysed oxidation of cyclopropyl fatty acids

Cryle, Max J., Hayes, Patricia Y. and De Voss, James J. (2012). Enzyme-substrate complementarity governs access to a cationic reaction manifold in the P450(BM3) -catalysed oxidation of cyclopropyl fatty acids. Chemistry : A European Journal, 18 (50), 15994-15999. doi: 10.1002/chem.201203035

Enzyme-substrate complementarity governs access to a cationic reaction manifold in the P450(BM3) -catalysed oxidation of cyclopropyl fatty acids

2012

Journal Article

Plakortolide stereochemistry revisited: the checkered history of plakortolides e and i

Yong, Ken W. L., Barnych, Bogdan, De Voss, James J., Vatele, Jean-Michael and Garson, Mary J. (2012). Plakortolide stereochemistry revisited: the checkered history of plakortolides e and i. Journal of Natural Products, 75 (10), 1792-1797. doi: 10.1021/np3005634

Plakortolide stereochemistry revisited: the checkered history of plakortolides e and i

2012

Journal Article

Structure and bioactivity of steroidal saponins isolated from the roots of Chamaelirium luteum (False Unicorn)

Challinor, Victoria L., Stuthe, Julia M. U., Parsons, Peter G., Lambert, Lynette K., Lehmann, Reginald P., Kitching, William and De Voss, James J. (2012). Structure and bioactivity of steroidal saponins isolated from the roots of Chamaelirium luteum (False Unicorn). Journal of Natural Products, 75 (8), 1469-1479. doi: 10.1021/np300393y

Structure and bioactivity of steroidal saponins isolated from the roots of Chamaelirium luteum (False Unicorn)

2012

Journal Article

An in vivo cytochrome P450(cin) (CYP176A1) catalytic system for metabolite production

Slessor, Kate E., Hawkes, David B., Farlow, Anthony, Pearson, Andrew G., Stok, Jeanette E. and De Voss, James J. (2012). An in vivo cytochrome P450(cin) (CYP176A1) catalytic system for metabolite production. Journal of Molecular Catalysis B: Enzymatic, 79, 15-20. doi: 10.1016/j.molcatb.2012.03.007

An in vivo cytochrome P450(cin) (CYP176A1) catalytic system for metabolite production

2012

Journal Article

Substrate analog studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P450 enzymes CYP124A1, CYP125A1 and CYP142A1

Johnston, Jonathan B., Singh, Arti A., Clary, Anaelle A., Chen, Chiung-Kuan, Hayes, Patricia Y., Chow, Sharon, De Voss, James J. and de Montellano, Paul R. O. (2012). Substrate analog studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P450 enzymes CYP124A1, CYP125A1 and CYP142A1. Bioorganic and Medicinal Chemistry, 20 (13), 4064-4081. doi: 10.1016/j.bmc.2012.05.003

Substrate analog studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P450 enzymes CYP124A1, CYP125A1 and CYP142A1

2012

Journal Article

NMR assignment of the absolute configuration of C-25 in furostanol steroidal saponins

Challinor, Victoria L., Piacente, Sonia and De Voss, James J. (2012). NMR assignment of the absolute configuration of C-25 in furostanol steroidal saponins. Steroids, 77 (6), 602-608. doi: 10.1016/j.steroids.2012.02.002

NMR assignment of the absolute configuration of C-25 in furostanol steroidal saponins