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2016 Journal Article In vivo and in vitro hydroxylation of cineole and camphor by cytochromes P450CYP101A1, CYP101B1 and N242A CYP176A1Stok, Jeanette E., Hall, Emma A., Stone, Isobella S. J, Noble, Margaret C., Wong, Siew Hoon, Bell, Stephen G. and De Voss, James J. (2016). In vivo and in vitro hydroxylation of cineole and camphor by cytochromes P450CYP101A1, CYP101B1 and N242A CYP176A1. Journal of Molecular Catalysis B: Enzymatic, 128, 52-64. doi: 10.1016/j.molcatb.2016.03.004 |
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2016 Journal Article The importance of the benzoic acid carboxylate moiety for substrate recognition by CYP199A4 from Rhodopseudomonas palustris HaA2Coleman, Tom, Chao, Rebecca R., de Voss, James J. and Bell, Stephen G. (2016). The importance of the benzoic acid carboxylate moiety for substrate recognition by CYP199A4 from Rhodopseudomonas palustris HaA2. Biochimica et Biophysica Acta, 1864 (6), 667-675. doi: 10.1016/j.bbapap.2016.03.006 |
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2016 Journal Article Cholesterol analogs with degradation-resistant alkyl side chains are effective Mycobacterium tuberculosis growth inhibitorsFrank, Daniel J., Zhao, Yan, Wong, Siew Hoon, Basudhar, Debashree, De Voss, James J. and De Montellano, Paul R. Ortiz (2016). Cholesterol analogs with degradation-resistant alkyl side chains are effective Mycobacterium tuberculosis growth inhibitors. Journal of Biological Chemistry, 291 (14), 7325-7333. doi: 10.1074/jbc.M115.708172 |
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2016 Journal Article Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene BioisostereChalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere. Angewandte Chemie International Edition, 55 (11), 8359-8359. doi: 10.1002/anie.201681161 |
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2016 Journal Article Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidationStok, Jeanette E., Chow, Sharon, Krenske, Elizabeth H., Farfan Soto, Clementina, Matyas, Csongor, Poirier, Raymond A., Williams, Craig M. and De Voss, James J. (2016). Direct observation of an oxepin from a bacterial cytochrome P450-catalyzed oxidation. Chemistry: A European Journal, 22 (13), 4408-4412. doi: 10.1002/chem.201600246 |
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2016 Journal Article Validating Eaton's hypothesis: cubane as a benzene bioisostereChalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Validating Eaton's hypothesis: cubane as a benzene bioisostere. Angewandte Chemie (International Edition), 55 (11), 3580-3585. doi: 10.1002/anie.201510675 |
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2016 Conference Publication An assessment of the utility of DNA barcoding in the quality control of herbal raw materials, extracts and finished productsWohlmuth, H., Leach, D., McGrath, K., Gordon, L., Mouatt, P. and De Voss, J. (2016). An assessment of the utility of DNA barcoding in the quality control of herbal raw materials, extracts and finished products. 9th Joint Meeting of AFERP, ASP, GA, JSP, PSE and SIF, Copenhagen, Denmark, 24 - 27 July 2016. Stuttgart, Germany: Georg Thieme Verlag. doi: 10.1055/s-0036-1597032 |
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2016 Journal Article Synthesis of L-Indospicine, [5,5,6-2H3 ]- L-Indospicine and L-NorindospicineLang, Cheng-Shan, Wong, Siew-Hoon, Chow, Sharon, Challinor, Victoria L., Yong, Ken W. L., Fletcher, Mary T., Arthur, Dionne M., Ng, Jack C. and De Voss, James J. (2016). Synthesis of L-Indospicine, [5,5,6-2H3 ]- L-Indospicine and L-Norindospicine. Organic and Biomolecular Chemistry, 14 (28), 6826-6832. doi: 10.1039/C6OB01187J |
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2016 Conference Publication Establishing compositional guidelines for flavonoids and saponins in Gynostemma pentaphyllumLeach, D., Ahmed, I., De Voss, J. and Wohlmuth, H. (2016). Establishing compositional guidelines for flavonoids and saponins in Gynostemma pentaphyllum. 9th Joint Meeting of AFERP, ASP, GA, JSP, PSE and SIF, Copenhagen Denmark, 24 - 27 July 2016. Stuttgart, Germany: Georg Thieme Verlag. doi: 10.1055/s-0036-1597033 |
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2015 Journal Article Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosaChallinor, Victoria L., Johnston, Ryne C., Bernhardt, Paul V., Lehmann, Reginald P., Krenske, Elizabeth H. and De Voss, James J. (2015). Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa. Chemical Science, 6 (10), 5740-5745. doi: 10.1039/c5sc02056e |
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2015 Journal Article CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivativesColeman, Tom, Chao, Rebecca R., Bruning, John B., De Voss, James J. and Bell, Stephen G. (2015). CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivatives. RSC Advances, 5 (64), 52007-52018. doi: 10.1039/c5ra08730a |
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2015 Book Chapter Cytochrome P450cin (CYP176A1)Stok, Jeanette E., Slessor, Kate E., Farlow, Anthony J., Hawkes, David B. and De Voss, James J. (2015). Cytochrome P450cin (CYP176A1). Monooxygenase, Peroxidase and Peroxygenase Properties and Mechanisms of Cytochrome P450. (pp. 319-339) edited by Eugene G. Hrycay and Stelvio M. Bandiera. New York, NY United States: Springer New York LLC. doi: 10.1007/978-3-319-16009-2_12 |
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2014 Journal Article Electrochemically mediated enantioselective reduction of chiral sulfoxidesChen, Kuan I., Challinor, Victoria L., Kielmann, Linda, Sharpe, Philip C., De Voss, James J., Kappler, Ulrike, McEwan, Alastair G. and Bernhardt, Paul V. (2014). Electrochemically mediated enantioselective reduction of chiral sulfoxides. Journal of Biological Inorganic Chemistry, 20 (2), 395-402. doi: 10.1007/s00775-014-1215-5 |
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2014 Journal Article Oxidative carbon-carbon bond cleavage is a key step in spiroacetal biosynthesis in the fruit fly Bactrocera cacuminataSingh, Arti A., Rowley, Jessica A., Schwartz, Brett D., Kitching, William and De Voss, James J. (2014). Oxidative carbon-carbon bond cleavage is a key step in spiroacetal biosynthesis in the fruit fly Bactrocera cacuminata. Journal of Organic Chemistry, 79 (17), 7799-7821. doi: 10.1021/jo500791y |
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2014 Journal Article Structural and mechanistic insight into alkane hydroxylation by Pseudomonas putida AlkBAlonso, Hernan, Kleifeld, Oded, Yeheskel, Adva, Ong, Poh C., Liu, Yu C., Stok, Jeanette E., De Voss, James J. and Roujeinikova, Anna (2014). Structural and mechanistic insight into alkane hydroxylation by Pseudomonas putida AlkB. Biochemical Journal, 460 (2), 283-293. doi: 10.1042/BJ20131648 |
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2014 Journal Article Carbon-Carbon bond cleavage in activation of the prodrug nabumetoneVarfaj, Fatbardha, Zulkifli, Siti N. A., Park, Hyoung-Goo, Challinor, Victoria L., De Voss, James J. and De Montellano, Paul R. Ortiz (2014). Carbon-Carbon bond cleavage in activation of the prodrug nabumetone. Drug Metabolism and Disposition, 42 (5), 828-838. doi: 10.1124/dmd.114.056903 |
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2013 Journal Article Synthesis and determination of the absolute configuration of (-)-(5R,6Z)-dendrolasin-5-acetate from the nudibranch Hypselodoris jacksoniMudianta, I. Wayan, Challinor, Victoria L., Winters, Anne E., Cheney, Karen L., De Voss, James J. and Garson, Mary J. (2013). Synthesis and determination of the absolute configuration of (-)-(5R,6Z)-dendrolasin-5-acetate from the nudibranch Hypselodoris jacksoni. Beilstein Journal of Organic Chemistry, 9 (1), 2925-2933. doi: 10.3762/bjoc.9.329 |
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2013 Journal Article Structure and absolute configuration of methyl (3R)-malonyl-(13S)-hydroxycheilanth-17-en-19-oate, a sesterterpene derivative from the roots of Aletris farinosaChallinor, Victoria L., Chap, Sonet, Lehmann, Reginald P., Bernhardt, Paul V. and De Voss, James J. (2013). Structure and absolute configuration of methyl (3R)-malonyl-(13S)-hydroxycheilanth-17-en-19-oate, a sesterterpene derivative from the roots of Aletris farinosa. Journal of Natural Products, 76 (4), 485-488. doi: 10.1021/np400035n |
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2013 Journal Article Synthesis of oxygenated cineole derivatives from cineole: utility of cytochrome P450(cin) as an enantioselective catalystFarlow, Anthony J., Bernhardt, Paul V. and De Voss, James J. (2013). Synthesis of oxygenated cineole derivatives from cineole: utility of cytochrome P450(cin) as an enantioselective catalyst. Tetrahedron: Asymmetry, 24 (5-6), 324-333. doi: 10.1016/j.tetasy.2013.02.004 |
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2013 Journal Article Cytochrome P450(cin) (CYP176A1) D241N: investigating the role of the conserved acid in the active site of cytochrome P450sStok, Jeanette E., Yamada, Sean, Farlow, Anthony J., Slessor, Kate E. and De Voss, James J. (2013). Cytochrome P450(cin) (CYP176A1) D241N: investigating the role of the conserved acid in the active site of cytochrome P450s. Biochimica et Biophysica Acta: Proteins and Proteomics, 1834 (3), 688-696. doi: 10.1016/j.bbapap.2012.12.022 |