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2001 Journal Article Alpha-conotoxins: Nicotinic acetylcholine receptor antagonists as pharmacological tools and potential drug leadsDutton, J. L. and Craik, D. J. (2001). Alpha-conotoxins: Nicotinic acetylcholine receptor antagonists as pharmacological tools and potential drug leads. Current Medicinal Chemistry, 8 (4), 327-344. doi: 10.2174/0929867013373453 |
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2001 Journal Article Ring flexibility within tricyclic antidepressant drugsCasarotto, M. G. and Craik, D. J. (2001). Ring flexibility within tricyclic antidepressant drugs. Journal of Pharmaceutical Sciences, 90 (6), 713-721. doi: 10.1002/jps.1027 |
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2001 Journal Article Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from rhesus macaque leukocytesTrabi, M., Schirra, H. J. and Craik, D. J. (2001). Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from rhesus macaque leukocytes. Biochemistry, 40 (14), 4211-4221. doi: 10.1021/bi002028t |
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2001 Journal Article Solution structures by H-1 NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutantKorsinczky, M. L. J., Schirra, H. J., Rosengren, K. J., West, J., Condie, B. A., Otvos, L., Anderson, M. A. and Craik, D. J. (2001). Solution structures by H-1 NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant. Journal of Molecular Biology, 311 (3), 579-591. doi: 10.1006/jmbi.2001.4887 |
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2001 Journal Article Circular proteins in plants - Solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensisFelizmenio-Quimio, M. E., Daly, N. L. and Craik, D. J. (2001). Circular proteins in plants - Solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensis. Journal of Biological Chemistry, 276 (25), 22875-22882. doi: 10.1074/jbc.M101666200 |
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2001 Journal Article Two new classes of conopeptides inhibit the alpha 1-adrenoceptor and noradrenaline transporterSharpe, I. A., Gehrmann, J., Loughnan, M. L., Thomas, L., Adams, D. A., Atkins, A., Palant, E., Craik, D. J., Adams, D. J., Alewood, P. F. and Lewis, R. J. (2001). Two new classes of conopeptides inhibit the alpha 1-adrenoceptor and noradrenaline transporter. Nature Neuroscience, 4 (9), 902-907. doi: 10.1038/nn0901-902 |
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2001 Journal Article Solution structure of BSTI: A new trypsin inhibitor from skin secretions of Bombina bombinaRosengren, K. J., Daly, N. L., Scanlon, M. J. and Craik, D. J. (2001). Solution structure of BSTI: A new trypsin inhibitor from skin secretions of Bombina bombina. Biochemistry, 40 (15), 4601-4609. doi: 10.1021/bi002623v |
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2001 Journal Article Plant cyclotides: circular, knotted peptide toxinsCraik, D. J. (2001). Plant cyclotides: circular, knotted peptide toxins. Toxicon, 39 (12), 1809-1813. doi: 10.1016/S0041-0101(01)00129-5 |
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2000 Journal Article Pharmaceutical applications of NMRCraik, David J. and Scanlon, Martin J. (2000). Pharmaceutical applications of NMR. Annual Reports on NMR Spectroscopy, 42, 115-174. |
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2000 Journal Article Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F)Poulsen, Sally-Ann, Watson, Andrew A., Fairlie, David P. and Craik, David J. (2000). Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F). Journal of Structural Biology, 130 (2-3), 142-152. doi: 10.1006/jsbi.2000.4267 |
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2000 Journal Article Insect peptides with improved protease-resistance protect mice against bacterial infectionOtvos, L. J., Bokonyi, K., Varga, I., Otvos, B. I., Hoffmann, R., Ertl, H. C. J., Wade, J. D., McManus, AM, Craik, D. J. and Bulet, P. (2000). Insect peptides with improved protease-resistance protect mice against bacterial infection. Protein Science, 9 (4), 742-749. doi: 10.1110/ps.9.4.742 |
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2000 Journal Article Inhibitors of beta-amyloid formation based on the beta-secretase cleavage siteAbbenante, G., Kovacs, D. M., Leung, D. L., Craik, D. J., Tanzi, R. E. and Fairlie, D. P. (2000). Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site. Biochemical And Biophysical Research Communications, 268 (1), 133-135. doi: 10.1006/bbrc.2000.2098 |
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2000 Journal Article Acyclic permutants of naturally occurring cyclic proteins - Characterization of cystine knot and beta-sheet formation in the macrocyclic polypeptide kalata B1Daly, NL and Craik, DJ (2000). Acyclic permutants of naturally occurring cyclic proteins - Characterization of cystine knot and beta-sheet formation in the macrocyclic polypeptide kalata B1. Journal of Biological Chemistry, 275 (25), 19068-19075. doi: 10.1074/jbc.M000450200 |
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2000 Journal Article Chemical synthesis, characterization and activity of RK-1, a novel alpha-defensin-related peptideDawson, Nicola F., Craik, David J., McManus, Ailsa M., Dashper, Stuart G., Reynolds, Eric C., Tregear, Geoffrey W., Otvos, Laszlo and Wade, John D. (2000). Chemical synthesis, characterization and activity of RK-1, a novel alpha-defensin-related peptide. Journal of Peptide Science, 6 (1), 19-25. doi: 10.1002/(SICI)1099-1387(200001)6:13.3.CO;2-T |
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2000 Journal Article Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's diseaseDaly, N. L., Hoffmann, R., Otvos, L. J. and Craik, D. J. (2000). Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease. Biochemistry, 39 (30), 9039-9046. doi: 10.1021/bi0004807 |
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2000 Journal Article Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa - 1. Isolation, characterization and chemical synthesisHill, J. M., Atkins, A. R., Loughnan, M. L., Jones, A., Adams, D. A., Martin, R. C., Lewis, R. J., Craik, D. J. and Alewood, P. F. (2000). Conotoxin TVIIA, a novel peptide from the venom of Conus tulipa - 1. Isolation, characterization and chemical synthesis. European Journal of Biochemistry, 267 (15), 4642-4648. doi: 10.1046/j.1432-1327.2000.01508.x |
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2000 Journal Article Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypesLewis, Richard J., Nielsen, Katherine J., Craik, David J., Loughnan, Marion L., Adams, Denise A., Sharpe, Iain A., Luchian, Tudor, Adams, David J., Bond, Trudy, Thomas, Linda, Jones, Alun, Matheson, Jodi-Lea, Drinkwater, Roger, Andrews, Peter R. and Alewood, Paul F. (2000). Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes. Journal of Biological Chemistry, 275 (45), 35335-35344. doi: 10.1074/jbc.M002252200 |
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2000 Journal Article Acyclic permutants of naturally occurring cyclic proteinsDaly, N. L. and Craik, D. J. (2000). Acyclic permutants of naturally occurring cyclic proteins. The Journal of Biological Chemistry, 275 (25), 19068-19075. |
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2000 Journal Article Three-dimensional structure of RK-1: A novel alpha-defensin peptideMcManus, A. M., Dawson, N. F., Wade, J. D., Carrington, L. E., Winzor, D. J. and Craik, D. J. (2000). Three-dimensional structure of RK-1: A novel alpha-defensin peptide. Biochemistry, 39 (51), 15757-15764. doi: 10.1021/bi000457l |
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2000 Journal Article Identification of initiation sites for T4 lysozyme folding using CD and NMR spectroscopy of peptide fragmentsNajbar, L. V., Craik, D. J., Wade, J. D. and McLeish, M. J. (2000). Identification of initiation sites for T4 lysozyme folding using CD and NMR spectroscopy of peptide fragments. Biochemistry, 39 (19), 5911-5920. doi: 10.1021/bi000070i |
