|
2025 Journal Article Autoimmune origin for immune checkpoint inhibitor-diabetes revealed by deep immune phenotyping of the pancreasQuandt, Zoe, Young, Arabella, Barlow, Graham Larson, Smith, Jennifer A, Kusmartseva, Irina, Dong, Shen, Shapiro, Melanie R, Kang, Jee Hye, Felton, Jamie L, Nguyen, Vinh Q, Szot, Greg, Hassoun, Assad A, Perdigoto, Ana Luisa, Herold, Kevan C, Nolan, Garry, Bollyky, Paul L, Brusko, Todd M, Nakayama, Maki, Cooper, Stewart and Anderson, Mark S (2025). Autoimmune origin for immune checkpoint inhibitor-diabetes revealed by deep immune phenotyping of the pancreas. Journal for immunotherapy of cancer, 13 (8) e011818, 1-9. doi: 10.1136/jitc-2025-011818 |
|
2024 Journal Article Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clonesSmith, Jennifer A., Yuen, Benjamin T. K., Purtha, Whitney, Balolong, Jared M., Phipps, Jonah D., Crawford, Frances, Bluestone, Jeffrey A., Kappler, John W. and Anderson, Mark S. (2024). Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones. Proceedings of the National Academy of Sciences of the United States of America, 121 (20) e2320268121, 1-10. doi: 10.1073/pnas.2320268121 |
|
2024 Journal Article Tracking the role of Aire in immune tolerance to the eye with a TCR transgenic mouse modelYin, Mianmian, Smith, Jennifer A, Chou, Marissa, Chan, Jackie, Jittayasothorn, Yingyos, Gould, Douglas B, Caspi, Rachel R, Anderson, Mark S and DeFranco, Anthony L (2024). Tracking the role of Aire in immune tolerance to the eye with a TCR transgenic mouse model. Proceedings of the National Academy of Sciences of the United States of America, 121 (5) e2311487121, 1-12. doi: 10.1073/pnas.2311487121 |
|
2023 Journal Article Tuning peptide specificity for T cell tolerance in Type 1 diabetesSmith, Jennifer Anne, Balolong, Jared, Jin, Nijun, Whitty, Caroline, Kappler, John W and Anderson, Mark S (2023). Tuning peptide specificity for T cell tolerance in Type 1 diabetes. The Journal of Immunology, 210 (Supplement_1). doi: 10.4049/jimmunol.210.supp.78.09 |
|
2022 Journal Article Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protectionVanDyke, Derek, Iglesias, Marcos, Tomala, Jakub, Young, Arabella, Smith, Jennifer, Perry, Joseph A., Gebara, Edward, Cross, Amy R., Cheung, Laurene S., Dykema, Arbor G., Orcutt-Jahns, Brian T., Henclova, Tereza, Golias, Jaroslav, Balolong, Jared, Tomasovic, Luke M., Funda, David, Meyer, Aaron S., Pardoll, Drew M., Hester, Joanna, Issa, Fadi, Hunter, Christopher A., Anderson, Mark S., Bluestone, Jeffrey A., Raimondi, Giorgio and Spangler, Jamie B. (2022). Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection. Cell Reports, 41 (3) 111478, 111478. doi: 10.1016/j.celrep.2022.111478 |
|
2022 Journal Article Immune-profiling of pancreatic tissue affected by immune checkpoint inhibitor-induced diabetes (CPI-D)Quandt, Zoe, Young, Arabella, Barlow, Graham, Dong, Shen, Smith, Jennifer, Kusmartseva, Irina, Brusko, Todd M., Cooper, Stewart and Anderson, Mark S. (2022). Immune-profiling of pancreatic tissue affected by immune checkpoint inhibitor-induced diabetes (CPI-D). Diabetes, 71 (S1). doi: 10.2337/db22-189-or |
|
2022 Conference Publication Autoantigen specific T-cell receptor induces organ-specific autoimmunity by escaping T-cell negative selectionYin, Mianmian, Smith, Jennifer A., Chou, Marissa, Chan, Jackie, Hu, Yongmei, Lowell, Clifford A., Gould, Douglas B., Anderson, Mark S. and DeFranco, Anthony L. (2022). Autoantigen specific T-cell receptor induces organ-specific autoimmunity by escaping T-cell negative selection. Immunology 2022™ Meeting, Portland, OR, United States, 6-10 May 2022. Cary, NC, United States: Oxford University Press. doi: 10.4049/jimmunol.208.supp.104.02 |
|
2021 Journal Article A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell toleranceWarshauer, Jeremy T, Belk, Julia A, Chan, Alice Y, Wang, Jiaxi, Gupta, Alexander R, Shi, Quanming, Skartsis, Nikolaos, Peng, Yani, Phipps, Jonah D, Acenas, Dante, Smith, Jennifer A, Tamaki, Stanley J, Tang, Qizhi, Gardner, James M, Satpathy, Ansuman T and Anderson, Mark S (2021). A human mutation in STAT3 promotes type 1 diabetes through a defect in CD8+ T cell tolerance. The Journal of Experimental Medicine, 218 (8) e20210759, 1-18. doi: 10.1084/jem.20210759 |
|
2021 Journal Article Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal treeHendley, Audrey M, Rao, Arjun A, Leonhardt, Laura, Ashe, Sudipta, Smith, Jennifer A, Giacometti, Simone, Peng, Xianlu L, Jiang, Honglin, Berrios, David I, Pawlak, Mathias, Li, Lucia Y, Lee, Jonghyun, Collisson, Eric A, Anderson, Mark S, Fragiadakis, Gabriela K, Yeh, Jen Jen, Ye, Chun Jimmie, Kim, Grace E, Weaver, Valerie M and Hebrok, Matthias (2021). Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree. eLife, 10 e67776, 1-29. doi: 10.7554/eLife.67776 |
|
2021 Conference Publication The role of Aire in the selection of regulatory T cells in type 1 diabetesBridge, Jennifer Anne, Balolong, Jared, Belk, Julia, Dong, Shen, Cramer, Nathan, Mowery, Cody, Crawford, Frances, Ye, Jimmy, Satpathy, Ansuman, Kappler, John W, Bluestone, Jeffrey A and Anderson, Mark S (2021). The role of Aire in the selection of regulatory T cells in type 1 diabetes. Immunology 2021™ Meeting, Virtual, 10-15 May 2021. Cary, NC, United States: Oxford University Press. doi: 10.4049/jimmunol.206.supp.51.07 |
|
2021 Journal Article T-cell receptor repertoire of mice with organ-specific autoimmunity resulting from a partial defect in T cell negative selection and dendritic cell enhancementYin, Mianmian, Smith, Jennifer A, Chou, Marissa, Chan, Jackie, Hu, Yongmei, Lowell, Clifford A, Gould, Douglas B, Anderson, Mark S and DeFranco, Anthony L (2021). T-cell receptor repertoire of mice with organ-specific autoimmunity resulting from a partial defect in T cell negative selection and dendritic cell enhancement. The Journal of Immunology, 206 (1_Supplement), 51.06-51.06. doi: 10.4049/jimmunol.206.supp.51.06 |
|
2020 Journal Article Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasisLee, James C., Mehdizadeh, Sadaf, Smith, Jennifer, Young, Arabella, Mufazalov, Ilgiz A., Mowery, Cody T., Daud, Adil and Bluestone, Jeffrey A. (2020). Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis. Science Immunology, 5 (52) eaba0759, 1-14. doi: 10.1126/sciimmunol.aba0759 |
|
2020 Journal Article Evaluation of SARS-CoV-2 serology assays reveals a range of test performanceWhitman, Jeffrey D., Hiatt, Joseph, Mowery, Cody T., Shy, Brian R., Yu, Ruby, Yamamoto, Tori N., Rathore, Ujjwal, Goldgof, Gregory M., Whitty, Caroline, Woo, Jonathan M., Gallman, Antonia E., Miller, Tyler E., Levine, Andrew G., Nguyen, David N., Bapat, Sagar P., Balcerek, Joanna, Bylsma, Sophia A., Lyons, Ana M., Li, Stacy, Wong, Allison Wai-yi, Gillis-Buck, Eva Mae, Steinhart, Zachary B., Lee, Youjin, Apathy, Ryan, Lipke, Mitchell J., Smith, Jennifer Anne, Zheng, Tina, Boothby, Ian C., Isaza, Erin ... Marson, Alexander (2020). Evaluation of SARS-CoV-2 serology assays reveals a range of test performance. Nature Biotechnology, 38 (10), 1174-1183. doi: 10.1038/s41587-020-0659-0 |
|
2020 Conference Publication Liver metastasis mediated control of distant tumor-specific immunity and response to checkpoint immunotherapyLee, James C., Mehdizadeh, Sadaf, Young, Arabella, Bridge, Jennifer, Mufazalov, Ilgiz A., Daud, Adil and Bluestone, Jeffrey A. (2020). Liver metastasis mediated control of distant tumor-specific immunity and response to checkpoint immunotherapy. AACR Annual Meeting, Electr Network, 22-24 June 2020. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2020-1031 |
|
2020 Conference Publication The role of Aire in the selection of regulatory T cells in diabetesBridge, Jennifer Anne, Balolong, Jared, Dong, Shen, Cramer, Nathan, Mowery, Cody, Crawford, Frances, Ye, Jimmie, Kappler, John W, Bluestone, Jeffrey A and Anderson, Mark S (2020). The role of Aire in the selection of regulatory T cells in diabetes. Immunology 2020™ Meeting, Honolulu, HI, United States, 8-12 May 2020. Oxford, United Kingdom: Oxford University Press. doi: 10.4049/jimmunol.204.supp.143.9 |
|
2019 Journal Article Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stageTuong, Zewen, Lewandowski, Andrew, Bridge, Jennifer, Gonzalez-Cruz, Jazmina, Yamada, Miko, Lambie, Duncan, Lewandowski, Richard, Steptoe, Raymond, Leggatt, Graham, Simpson, Fiona, Frazer, Ian, Soyer, Peter and Wells, James W. (2019). Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage. Scientific Reports, 9 (1) 17754, 17754. doi: 10.1038/s41598-019-54435-0 |
|
2018 Journal Article Cytokines, chemokines, and other biomarkers of response for checkpoint inhibitor therapy in skin cancerBridge, Jennifer A., Lee, James C., Daud, Adil, Wells, James W. and Bluestone, Jeffrey A. (2018). Cytokines, chemokines, and other biomarkers of response for checkpoint inhibitor therapy in skin cancer. Frontiers in Medicine, 5 (DEC) 351, 351. doi: 10.3389/fmed.2018.00351 |
|
2018 Conference Publication Aire-dependent thymic FoxP3+ regulatory T cells in Type 1 DiabetesBridge, Jennifer Anne, Yuen, Benjamin, Dong, Shen, Ye, Jimmy, Kappler, John W, Bluestone, Jeffrey A and Anderson, Mark S (2018). Aire-dependent thymic FoxP3+ regulatory T cells in Type 1 Diabetes. Immunology 2018™ Meeting, Austin, TX, United States, 4-8 May 2018. Cary, NC, United States: Oxford University Press. doi: 10.4049/jimmunol.200.supp.101.10 |
|
2018 Conference Publication Antigen discovery for regulatory T cells (Tregs) in type-1 diabetes (T1D)Dong, Shen, Xu, Daqi, Bridge, Jennifer Anne, Purtha, Whitney, Spence, Allyson, Wells, Danny, Wang, Xiao Hua, Tang, Qizhi, Anderson, Mark S and Bluestone, Jeffrey A (2018). Antigen discovery for regulatory T cells (Tregs) in type-1 diabetes (T1D). Immunology 2018™ Meeting, Austin, TX, United States, 4-8 May 2018. Cary, NC, United States: Oxford University Press. doi: 10.4049/jimmunol.200.supp.101.12 |
|
2017 Journal Article CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skinOvergaard, Nana H., Cruz, Jazmina L., Bridge, Jennifer A., Nel, Hendrik J., Frazer, Ian H., La Gruta, Nicole K., Blumenthal, Antje, Steptoe, Raymond J. and Wells, James W. (2017). CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin. Journal of Leukocyte Biology, 102 (3), 837-844. doi: 10.1189/jlb.1AB0217-065R |
