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2017

Journal Article

Case Report: Encephalitis, with Brainstem Involvement, Following Checkpoint Inhibitor Therapy in Metastatic Melanoma

Bossart, Simon, Thurneysen, Selina, Rushing, Elisabeth, Frontzek, Karl, Leske, Henning, Mihic-Probst, Daniela, Nagel, Hannes W., Mangana, Johanna, Goldinger, Simone M. and Dummer, Reinhard (2017). Case Report: Encephalitis, with Brainstem Involvement, Following Checkpoint Inhibitor Therapy in Metastatic Melanoma. Oncologist, 22 (6), 749-753. doi: 10.1634/theoncologist.2016-0366

Case Report: Encephalitis, with Brainstem Involvement, Following Checkpoint Inhibitor Therapy in Metastatic Melanoma

2017

Conference Publication

Sarcoid-like reactions under modern melanoma treatment

Dimitriou, F., Frauchiger, A., Goldinger, S. M., Braun, R., Mangana, J. and Dummer, R. (2017). Sarcoid-like reactions under modern melanoma treatment. HOBOKEN: WILEY.

Sarcoid-like reactions under modern melanoma treatment

2017

Conference Publication

Thin melanoma in Swiss Patients: A clinicopathological comparison

Kaufmann, C., Mangana, J., Cheng, P., Ramelyte, E., Goldinger, S. M., Levesque, M. P. and Dummer, R. (2017). Thin melanoma in Swiss Patients: A clinicopathological comparison. HOBOKEN: WILEY.

Thin melanoma in Swiss Patients: A clinicopathological comparison

2017

Conference Publication

The peripheral blood TCR repertoire might facilitate patient stratification for immune checkpoint blockade inhibition in metastatic melanoma

Schindler, S., Courtier, A., Jaberg-Bentele, N., Goldinger, S., Manuel, M., Perez, S., Mouret, J. -F., Nguyen-Kim, T. D. L., Raaijmakers, M., Kvistborg, P., Pasqua, N., Haanen, J., Dummer, R. and Levesque, M. (2017). The peripheral blood TCR repertoire might facilitate patient stratification for immune checkpoint blockade inhibition in metastatic melanoma. HOBOKEN: WILEY.

The peripheral blood TCR repertoire might facilitate patient stratification for immune checkpoint blockade inhibition in metastatic melanoma

2017

Journal Article

Does the distribution pattern of brain metastases during BRAF inhibitor therapy reflect phenotype switching?

Haueis, Silvia A., Kranzlin, Pascale, Mangana, Joanna, Cheng, Phil F., Urosevic-Maiwald, Mirjana, Braun, Ralph P., Levesque, Mitchell P., Dummer, Reinhard and Goldinger, Simone M. (2017). Does the distribution pattern of brain metastases during BRAF inhibitor therapy reflect phenotype switching?. Melanoma Research, 27 (3), 231-237. doi: 10.1097/CMR.0000000000000338

Does the distribution pattern of brain metastases during BRAF inhibitor therapy reflect phenotype switching?

2017

Conference Publication

Incidence, features and management of radionecrosis (RN) in melanoma patients (pts) treated with cerebral radiotherapy (RT) and anti-PD-1 antibodies (PD1)

da Silva, Ines Esteves Domingues Pires, Johnpulle, Romany Anne Nilanthi, Banks, Patricia Diana, Grass, G. Daniel, Smith, Jess Louise, Everett, Ashlyn S., Goldinger, Simone M., -Thomson, Rachel Roberts, Millward, Michael, Glitza, Isabella Claudia, Haydu, Lauren Elaine, Atkinson, Victoria, Wang, Tim, Eroglu, Zeynep, Conry, Robert Martin, Shackleton, Mark J., Hong, Angela, Long, Georgina V., Johnson, Douglas Buckner and Menzies, Alexander M. (2017). Incidence, features and management of radionecrosis (RN) in melanoma patients (pts) treated with cerebral radiotherapy (RT) and anti-PD-1 antibodies (PD1). 53rd Annual Clinical Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 02-07, 2017. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/JCO.2017.35.15_suppl.9513

Incidence, features and management of radionecrosis (RN) in melanoma patients (pts) treated with cerebral radiotherapy (RT) and anti-PD-1 antibodies (PD1)

2017

Conference Publication

Hyperproliferative keratinocytic cutaneous adverse events and inflammatory palmoplantar erythrodysesthesia in melanoma patients treated with encorafenib compared to other BRAF inhibitors

Goldinger, Simone M., Graf, Natalie P., Galliker, Nadja, Conrad, Samuel and Dummer, Reinhard (2017). Hyperproliferative keratinocytic cutaneous adverse events and inflammatory palmoplantar erythrodysesthesia in melanoma patients treated with encorafenib compared to other BRAF inhibitors. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 02-06, 2017. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/JCO.2017.35.15_suppl.9590

Hyperproliferative keratinocytic cutaneous adverse events and inflammatory palmoplantar erythrodysesthesia in melanoma patients treated with encorafenib compared to other BRAF inhibitors

2017

Conference Publication

Re-challenge with BRAF-directed treatment: A multi-institutional retrospective study

Valpione, Sara, Carlino, Matteo S., Mangana, Joanna, Mooradian, Meghan, McArthur, Grant A., Schadendorf, Dirk, Hauschild, Axel, Long, Georgina V., Arance, Ana M., Ascierto, Paolo Antonio, Maio, Michele, De Rosa, Francesco, Larkin, James M. G., Park, John J., Goldinger, Simone M., Flaherty, Keith, Xu, Wen, Livingstone, Elisabeth, Weichenthal, Michael and Lorigan, Paul (2017). Re-challenge with BRAF-directed treatment: A multi-institutional retrospective study. 53rd Annual Clinical Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 02-07, 2017. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/JCO.2017.35.15_suppl.9512

Re-challenge with BRAF-directed treatment: A multi-institutional retrospective study

2017

Journal Article

Adjuvant Therapy in High-Risk Stage III Cutaneous Melanoma

Kaufmann, Fabrice and Goldinger, Simone M. (2017). Adjuvant Therapy in High-Risk Stage III Cutaneous Melanoma. International Journal of Radiation Oncology Biology Physics, 98 (1), 15-16. doi: 10.1016/j.ijrobp.2017.01.245

Adjuvant Therapy in High-Risk Stage III Cutaneous Melanoma

2017

Journal Article

Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC

Tumeh, Paul C., Hellmann, Matthew D., Hamid, Omid, Tsai, Katy K., Loo, Kimberly L., Gubens, Matthew A., Rosenblum, Michael, Harview, Christina L., Taube, Janis M., Handley, Nathan, Khurana, Neharika, Nosrati, Adi, Krummel, Matthew F., Tucker, Andrew, Sosa, Eduardo V., Sanchez, Phillip J., Banayan, Nooriel, Osorio, Juan C., Nguyen-Kim, Dan L., Chang, Jeremy, Shintaku, I. Peter, Boasberg, Peter D., Taylor, Emma J., Munster, Pamela N., Algazi, Alain P., Chmielowski, Bartosz, Dummer, Reinhard, Grogan, Tristan R., Elashoff, David ... Daud, Adil (2017). Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC. Cancer Immunology Research, 5 (5), 417-424. doi: 10.1158/2326-6066.CIR-16-0325

Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC

2017

Journal Article

Evaluation of clinicopathological factors in PD-1 response: derivation and validation of a prediction scale for response to PD-1 monotherapy

Nosrati, Adi, Tsai, Katy K., Goldinger, Simone M., Tumeh, Paul, Grimes, Barbara, Loo, Kimberly, Algazi, Alain P., Thi Dan Linh Nguyen-Kim, , Levesque, Mitchell, Dummer, Reinhard, Hamid, Omid and Daud, Adil (2017). Evaluation of clinicopathological factors in PD-1 response: derivation and validation of a prediction scale for response to PD-1 monotherapy. British Journal of Cancer, 116 (9), 1141-1147. doi: 10.1038/bjc.2017.70

Evaluation of clinicopathological factors in PD-1 response: derivation and validation of a prediction scale for response to PD-1 monotherapy

2017

Journal Article

Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma

Zimmer, Lisa, Apuri, Susmitha, Eroglu, Zeynep, Kottschade, Lisa A., Forschner, Andrea, Gutzmer, Ralf, Schlaak, Max, Heinzerling, Lucie, Krackhardt, Angela M., Loquai, Carmen, Markovic, Svetomir N., Joseph, Richard W., Markey, Kelly, Utikal, Jochen S., Weishaupt, Carsten, Goldinger, Simone M., Sondak, Vernon K., Zager, Jonathan S., Schadendorf, Dirk and Khushalani, Nikhil I. (2017). Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma. European Journal of Cancer, 75, 47-55. doi: 10.1016/j.ejca.2017.01.009

Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma

2017

Journal Article

A review of serious adverse effects under treatment with checkpoint inhibitors

Heinzerling, Lucie and Goldinger, Simone M. (2017). A review of serious adverse effects under treatment with checkpoint inhibitors. Current Opinion in Oncology, 29 (2), 136-144. doi: 10.1097/CCO.0000000000000358

A review of serious adverse effects under treatment with checkpoint inhibitors

2017

Journal Article

Developments in targeted therapy in melanoma

Amann, V. C., Ramelyte, E., Thurneysen, S., Pitocco, R., Bentele-Jaberg, N., Goldinger, S. M., Dummer, R. and Mangana, J. (2017). Developments in targeted therapy in melanoma. Ejso, 43 (3), 581-593. doi: 10.1016/j.ejso.2016.10.014

Developments in targeted therapy in melanoma

2017

Journal Article

Critical aspects to achieve a high-quality melanoma clinic

Dummer, Reinhard, Ramelyte, Egle, Levesque, Mitch, Goldinger, Simone M. and Braun, Ralph P. (2017). Critical aspects to achieve a high-quality melanoma clinic. Current Opinion in Oncology, 29 (2), 145-150. doi: 10.1097/CCO.0000000000000357

Critical aspects to achieve a high-quality melanoma clinic

2016

Journal Article

Pembrolizumab-triggered Uveitis: An Additional Surrogate Marker for Responders in Melanoma Immunotherapy?

Diem, Stefan, Keller, Fabienne, Ruesch, Reinhard, Maillard, Samia A., Speiser, Daniel E., Dummer, Reinhard, Siano, Marco, Urner-Bloch, Ursula, Goldinger, Simone M. and Flatz, Lukas (2016). Pembrolizumab-triggered Uveitis: An Additional Surrogate Marker for Responders in Melanoma Immunotherapy?. Journal of Immunotherapy, 39 (9), 379-382. doi: 10.1097/CJI.0000000000000143

Pembrolizumab-triggered Uveitis: An Additional Surrogate Marker for Responders in Melanoma Immunotherapy?

2016

Journal Article

An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel

Thurneysen, S., Cheng, P. F., Nagel, H. W., Kunz, M., Jaberg-Bentele, N., Nageli, M., Ziegler, M., Guenova, E., Goldinger, S. M., Mangana, J., Levesque, M. P. and Dummer, R. (2016). An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel. British Journal of Dermatology, 175 (5), 966-978. doi: 10.1111/bjd.14727

An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel

2016

Conference Publication

A phase I, open-label study of pasireotide in patients with BRAF-and NRAS-wild type, unresectable and or metastatic melanoma

Dummer, R., Michielin, O. A., Nageli, M., Goldinger, S. M., Campigotto, F., Kriemler-Krahn, U., Schmid, H., Pedroncelli, A., Micaletto, S. and Schadendorf, D. (2016). A phase I, open-label study of pasireotide in patients with BRAF-and NRAS-wild type, unresectable and or metastatic melanoma. OXFORD: OXFORD UNIV PRESS. doi: 10.1093/annonc/mdw379.43

A phase I, open-label study of pasireotide in patients with BRAF-and NRAS-wild type, unresectable and or metastatic melanoma

2016

Conference Publication

Systemic treatment influences on immune accessibility of melanoma: A retrospective histopathological investigation

Krahenbuhl, L., Goldinger, S. M., Kerl, K., Kempf, W., Chevolet, I., Brochez, L., Cheng, P., Mangana, J., Levesque, M. P. and Dummer, R. (2016). Systemic treatment influences on immune accessibility of melanoma: A retrospective histopathological investigation. OXFORD: OXFORD UNIV PRESS. doi: 10.1093/annonc/mdw379.28

Systemic treatment influences on immune accessibility of melanoma: A retrospective histopathological investigation

2016

Conference Publication

Does the distribution pattern of brain metastases during BRAF inhibitor therapy reflect the phenotype switch?

Haueis, S., Kranzlin, P., Cheng, P., Mangana, J., Dummer, R. and Goldinger, S. (2016). Does the distribution pattern of brain metastases during BRAF inhibitor therapy reflect the phenotype switch?. HOBOKEN: WILEY-BLACKWELL.

Does the distribution pattern of brain metastases during BRAF inhibitor therapy reflect the phenotype switch?