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2016

Journal Article

MEK inhibitor-associated retinopathy (MEKAR) in metastatic melanoma: Long-term ophthalmic effects

Urner-Bloch, U., Urner, M., Jaberg-Bentele, N., Frauchiger, A. L., Dummer, R. and Goldinger, S. M. (2016). MEK inhibitor-associated retinopathy (MEKAR) in metastatic melanoma: Long-term ophthalmic effects. European Journal of Cancer, 65, 130-138. doi: 10.1016/j.ejca.2016.06.018

MEK inhibitor-associated retinopathy (MEKAR) in metastatic melanoma: Long-term ophthalmic effects

2016

Journal Article

Cytotoxic Cutaneous Adverse Drug Reactions during Anti-PD-1 Therapy

Goldinger, Simone M., Stieger, Pascale, Meier, Barbara, Micaletto, Sara, Contassot, Emmanuel, French, Lars E. and Dummer, Reinhard (2016). Cytotoxic Cutaneous Adverse Drug Reactions during Anti-PD-1 Therapy. Clinical Cancer Research, 22 (16), 4023-4029. doi: 10.1158/1078-0432.CCR-15-2872

Cytotoxic Cutaneous Adverse Drug Reactions during Anti-PD-1 Therapy

2016

Conference Publication

Safety and anti-tumor activity of Pasireotide in patients with BRAF- and NRAS-wild type, unresectable and or metastatic melanoma: a phase I, open-label, single-arm study

Schadendorf, D., Michielin, O., Nageli, M., Goldinger, S. M., Campigotto, F., Kriemler-Krahn, U., Schmid, H. A., Pedroncelli, A. M., Micaletto, S. and Dummer, R. (2016). Safety and anti-tumor activity of Pasireotide in patients with BRAF- and NRAS-wild type, unresectable and or metastatic melanoma: a phase I, open-label, single-arm study. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Safety and anti-tumor activity of Pasireotide in patients with BRAF- and NRAS-wild type, unresectable and or metastatic melanoma: a phase I, open-label, single-arm study

2016

Conference Publication

Does the distribution pattern of brain metastases during BRAF inhibitor therapy reflect the phenotype switch?

Haueis, S., Kranzlin, P., Cheng, P. F., Mangana, J., Dummer, R. and Goldinger, S. M. (2016). Does the distribution pattern of brain metastases during BRAF inhibitor therapy reflect the phenotype switch?. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Does the distribution pattern of brain metastases during BRAF inhibitor therapy reflect the phenotype switch?

2016

Conference Publication

The value of PET/CT patterns in response prediction of metastasized melanoma treated with ipilimumab

Urosevic-Maiwald, M., Goldinger, S. M., Sommerauer, M., Dummer, R. and Schaefer, N. G. (2016). The value of PET/CT patterns in response prediction of metastasized melanoma treated with ipilimumab. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

The value of PET/CT patterns in response prediction of metastasized melanoma treated with ipilimumab

2016

Conference Publication

Multi-center real-life experience with checkpoint inhibitors and targeted therapy agents in advanced melanoma patients in Switzerland

Mangana, J., Amann, V. C., Goldinger, S. M., Kaufmann, C., Frauchiger, A. L., Cheng, P., Stoegner, V., Held, U., Von Moos, R., Romano, E., Michielin, O., Braun, R., Levesque, M. P. and Dummer, R. (2016). Multi-center real-life experience with checkpoint inhibitors and targeted therapy agents in advanced melanoma patients in Switzerland. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

Multi-center real-life experience with checkpoint inhibitors and targeted therapy agents in advanced melanoma patients in Switzerland

2016

Conference Publication

An exploratory study investigating the metabolic activity and local cytokine profile in melanoma patients treated with pazopanib and paclitaxel

Thurneysen, S., Cheng, P. F., Nagel, H. W., Kunz, M., Jaberg-Bentele, N., Naegeli, M., Guenova-Hotzenecker, E., Goldinger, S., Mangana, J., Levesque, M. P. and Dummer, R. (2016). An exploratory study investigating the metabolic activity and local cytokine profile in melanoma patients treated with pazopanib and paclitaxel. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

An exploratory study investigating the metabolic activity and local cytokine profile in melanoma patients treated with pazopanib and paclitaxel

2016

Journal Article

Efficacy and Safety of AP0866 in Patients With Refractory or Relapsed Cutaneous T-Cell Lymphoma: A Phase 2 Clinical Trial

Goldinger, Simone M., Bischof, Sharon Gobbi, Fink-Puches, Regina, Klemke, Claus-Detlev, Dreno, Brigitte, Bagot, Martine and Dummer, Reinhard (2016). Efficacy and Safety of AP0866 in Patients With Refractory or Relapsed Cutaneous T-Cell Lymphoma: A Phase 2 Clinical Trial. Jama Dermatology, 152 (7), 837-839. doi: 10.1001/jamadermatol.2016.0401

Efficacy and Safety of AP0866 in Patients With Refractory or Relapsed Cutaneous T-Cell Lymphoma: A Phase 2 Clinical Trial

2016

Journal Article

Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy

Zimmer, Lisa, Goldinger, Simone M., Hofmann, Lars, Loquai, Carmen, Ugurel, Selma, Thomas, Ioannis, Schmidgen, Maria I., Gutzmer, Ralf, Utikal, Jochen S., Goeppner, Daniela, Hassel, Jessica C., Meier, Friedegund, Tietze, Julia K., Forschner, Andrea, Weishaupt, Carsten, Leverkus, Martin, Wahl, Renate, Dietrich, Ursula, Garbe, Claus, Kirchberger, Michael C., Eigentler, Thomas, Berking, Carola, Gesierich, Anja, Krackhardt, Angela M., Schadendorf, Dirk, Schuler, Gerold, Dummer, Reinhard and Heinzerling, Lucie M. (2016). Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy. European Journal of Cancer, 60, 210-225. doi: 10.1016/j.ejca.2016.02.024

Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy

2016

Journal Article

Pyogenic granuloma in patients treated with selective BRAF inhibitors: another manifestation of paradoxical pathway activation

Henning, Benjamin, Stieger, Pascale, Kamarachev, Jivko, Dummer, Reinhard and Goldinger, Simone M. (2016). Pyogenic granuloma in patients treated with selective BRAF inhibitors: another manifestation of paradoxical pathway activation. Melanoma Research, 26 (3), 304-307. doi: 10.1097/CMR.0000000000000248

Pyogenic granuloma in patients treated with selective BRAF inhibitors: another manifestation of paradoxical pathway activation

2016

Journal Article

Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy

Hofmann, Lars, Forschner, Andrea, Loquai, Carmen, Goldinger, Simone M., Zimmer, Lisa, Ugurel, Selma, Schmidgen, Maria I., Gutzmer, Ralf, Utikal, Jochen S., Goeppner, Daniela, Hassel, Jessica C., Meier, Friedegund, Tietze, Julia K., Thomas, Ioannis, Weishaupt, Carsten, Leverkus, Martin, Wahl, Renate, Dietrich, Ursula, Garbe, Claus, Kirchberger, Michael C., Eigentler, Thomas, Berking, Carola, Gesierich, Anja, Krackhardt, Angela M., Schadendorf, Dirk, Schuler, Gerold, Dummer, Reinhard and Heinzerling, Lucie M. (2016). Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy. European Journal of Cancer, 60, 190-209. doi: 10.1016/j.ejca.2016.02.025

Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy

2016

Conference Publication

The peripheral blood TCR repertoire to facilitate patient stratification for immune checkpoint blockade inhibition in metastatic melanoma

Goldinger, Simone M., Courtier, Anais, Jaberg-Bentele, Nicoletta F., Schindler, Sabrina, Manuel, Manuarii, Plantier, Nadia, Treillard, Bertrand, Noel, Marlene, Thi Dan Linh Nguyen-Kim, , Raaijmakers, Marieke Ineke Geertje, Kvistborg, Pia, Haanen, John B. A. G., Dummer, Reinhard and Levesque, Mitchell (2016). The peripheral blood TCR repertoire to facilitate patient stratification for immune checkpoint blockade inhibition in metastatic melanoma. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 03-07, 2016. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/JCO.2016.34.15_suppl.3026

The peripheral blood TCR repertoire to facilitate patient stratification for immune checkpoint blockade inhibition in metastatic melanoma

2016

Conference Publication

Derivation and validation of a prediction scale for response to PD-1 monotherapy

Nosrati, Adi, Goldinger, Simone M., Tsai, Katy K., Loo, Kimberly, Tumeh, Paul, Hamid, Omid, Algazi, Alain Patrick, Levesque, Mitchell P., Dummer, Reinhard and Daud, Adil (2016). Derivation and validation of a prediction scale for response to PD-1 monotherapy. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 03-07, 2016. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/JCO.2016.34.15_suppl.9514

Derivation and validation of a prediction scale for response to PD-1 monotherapy

2016

Conference Publication

Correlation between metastatic site and response to anti-Programmed Death-1 (PD-1) agents in melanoma

Goldinger, Simone M., Tsai, Katy K., Tumeh, Paul, Hamid, Omid, Nosrati, Adi, Loo, Kimberly, Grimes, Barbara, Algazi, Alain Patrick, Levesque, Mitchell P., Dummer, Reinhard and Daud, Adil (2016). Correlation between metastatic site and response to anti-Programmed Death-1 (PD-1) agents in melanoma. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 03-07, 2016. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/JCO.2016.34.15_suppl.9549

Correlation between metastatic site and response to anti-Programmed Death-1 (PD-1) agents in melanoma

2016

Journal Article

Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status

Frauchiger, A. L., Mangana, J., Rechsteiner, M., Moch, H., Seifert, B., Braun, R. P., Dummer, R. and Goldinger, S. M. (2016). Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status. British Journal of Dermatology, 174 (4), 823-830. doi: 10.1111/bjd.14347

Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status

2016

Journal Article

Treatment of melanoma brain metastases

Goldinger, Simone M., Panje, Cedric and Nathan, Paul (2016). Treatment of melanoma brain metastases. Current Opinion in Oncology, 28 (2), 159-165. doi: 10.1097/CCO.0000000000000270

Treatment of melanoma brain metastases

2016

Conference Publication

A distinct role for eosinophil and neutrophil granulocytes in patients with advanced melanoma receiving selective BRAF inhibitors

Cosgarea, I., Franklin, C., Schwamborn, M., Sucker, A., Griewank, K. G., Weide, B., Loquai, C., Hassel, J. C., Kaehler, K. C., Utikal, J., Gutzmer, R., Goldinger, S. M., Paschen, A., Schadendorf, D. and Schilling, B. (2016). A distinct role for eosinophil and neutrophil granulocytes in patients with advanced melanoma receiving selective BRAF inhibitors. 43rd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung-e-V (ADF), Vienna Austria, Mar 10-12, 2016. HOBOKEN: WILEY-BLACKWELL.

A distinct role for eosinophil and neutrophil granulocytes in patients with advanced melanoma receiving selective BRAF inhibitors

2016

Journal Article

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8<SUP>+</SUP> T-cell responses in melanoma patients (vol 42, pg 3049, 2012)

Goldinger, Simone M., Dummer, Reinhard, Baumgaertner, Petra, Mihic-Probst, Daniela, Schwarz, Katrin, Hammann-Haenni, Anya, Willers, Joerg, Geldhof, Christine, Prior, John O., Kuendig, Thomas M., Michielin, Olivier, Bachmann, Martin F. and Speiser, Daniel E. (2016). Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8+ T-cell responses in melanoma patients (vol 42, pg 3049, 2012). European Journal of Immunology, 46 (2), 493-493. doi: 10.1002/eji.201670027

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8<SUP>+</SUP> T-cell responses in melanoma patients (vol 42, pg 3049, 2012)

2016

Journal Article

Efficacy and safety of oral alitretinoin in severe oral lichen planus - results of a prospective pilot study

Kunz, M., Urosevic-Maiwald, M., Goldinger, S. M., Frauchiger, A. L., Dreier, J., Belloni, B., Mangana, J., Jenni, D., Dippel, M., Cozzio, A., Guenova, E., Kamarachev, J., French, L. E. and Dummer, R. (2016). Efficacy and safety of oral alitretinoin in severe oral lichen planus - results of a prospective pilot study. Journal of the European Academy of Dermatology and Venereology, 30 (2), 293-298. doi: 10.1111/jdv.13444

Efficacy and safety of oral alitretinoin in severe oral lichen planus - results of a prospective pilot study

2016

Journal Article

Noncutaneous Melanomas: A Single-Center Analysis

Del Prete, Valerio, Chaloupka, Karla, Holzmann, David, Fink, Daniel, Levesque, Mitchell, Dummer, Reinhard and Goldinger, Simone M. (2016). Noncutaneous Melanomas: A Single-Center Analysis. Dermatology, 232 (1), 22-29. doi: 10.1159/000441444

Noncutaneous Melanomas: A Single-Center Analysis