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2016

Conference Publication

Correlation between metastatic site and response to anti-Programmed Death-1 (PD-1) agents in melanoma

Goldinger, Simone M., Tsai, Katy K., Tumeh, Paul, Hamid, Omid, Nosrati, Adi, Loo, Kimberly, Grimes, Barbara, Algazi, Alain Patrick, Levesque, Mitchell P., Dummer, Reinhard and Daud, Adil (2016). Correlation between metastatic site and response to anti-Programmed Death-1 (PD-1) agents in melanoma. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago Il, Jun 03-07, 2016. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. doi: 10.1200/JCO.2016.34.15_suppl.9549

Correlation between metastatic site and response to anti-Programmed Death-1 (PD-1) agents in melanoma

2016

Journal Article

Erratum for the report "genomic correlates of response to CTLA-4 blockade in metastatic melanoma"

Van Allen, E. M., Miao, D., Schilling, B., Shukla, S. A., Blank, C., Zimmer, L., Sucker, A., Hillen, U., Geukes Foppen, M. H., Goldinger, Simone M., Utikal, J., Hassel, J. C., Weide, B., Kaehler, K. C., Loquai, C., Mohr, P., Gutzmer, R., Dummer, R., Gabriel, S., Wu, C. J., Schadendorf, D. and Garraway, L. A. (2016). Erratum for the report "genomic correlates of response to CTLA-4 blockade in metastatic melanoma". Science, 352 (6283). doi: 10.1126/science.aaf8264

Erratum for the report "genomic correlates of response to CTLA-4 blockade in metastatic melanoma"

2016

Journal Article

Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status

Frauchiger, A. L., Mangana, J., Rechsteiner, M., Moch, H., Seifert, B., Braun, R. P., Dummer, R. and Goldinger, S. M. (2016). Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status. British Journal of Dermatology, 174 (4), 823-830. doi: 10.1111/bjd.14347

Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status

2016

Journal Article

Treatment of melanoma brain metastases

Goldinger, Simone M., Panje, Cedric and Nathan, Paul (2016). Treatment of melanoma brain metastases. Current Opinion in Oncology, 28 (2), 159-165. doi: 10.1097/CCO.0000000000000270

Treatment of melanoma brain metastases

2016

Conference Publication

A distinct role for eosinophil and neutrophil granulocytes in patients with advanced melanoma receiving selective BRAF inhibitors

Cosgarea, I., Franklin, C., Schwamborn, M., Sucker, A., Griewank, K. G., Weide, B., Loquai, C., Hassel, J. C., Kaehler, K. C., Utikal, J., Gutzmer, R., Goldinger, S. M., Paschen, A., Schadendorf, D. and Schilling, B. (2016). A distinct role for eosinophil and neutrophil granulocytes in patients with advanced melanoma receiving selective BRAF inhibitors. 43rd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung-e-V (ADF), Vienna Austria, Mar 10-12, 2016. HOBOKEN: WILEY-BLACKWELL.

A distinct role for eosinophil and neutrophil granulocytes in patients with advanced melanoma receiving selective BRAF inhibitors

2016

Journal Article

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8<SUP>+</SUP> T-cell responses in melanoma patients (vol 42, pg 3049, 2012)

Goldinger, Simone M., Dummer, Reinhard, Baumgaertner, Petra, Mihic-Probst, Daniela, Schwarz, Katrin, Hammann-Haenni, Anya, Willers, Joerg, Geldhof, Christine, Prior, John O., Kuendig, Thomas M., Michielin, Olivier, Bachmann, Martin F. and Speiser, Daniel E. (2016). Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8+ T-cell responses in melanoma patients (vol 42, pg 3049, 2012). European Journal of Immunology, 46 (2), 493-493. doi: 10.1002/eji.201670027

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8<SUP>+</SUP> T-cell responses in melanoma patients (vol 42, pg 3049, 2012)

2016

Journal Article

Efficacy and safety of oral alitretinoin in severe oral lichen planus - results of a prospective pilot study

Kunz, M., Urosevic-Maiwald, M., Goldinger, S. M., Frauchiger, A. L., Dreier, J., Belloni, B., Mangana, J., Jenni, D., Dippel, M., Cozzio, A., Guenova, E., Kamarachev, J., French, L. E. and Dummer, R. (2016). Efficacy and safety of oral alitretinoin in severe oral lichen planus - results of a prospective pilot study. Journal of the European Academy of Dermatology and Venereology, 30 (2), 293-298. doi: 10.1111/jdv.13444

Efficacy and safety of oral alitretinoin in severe oral lichen planus - results of a prospective pilot study

2016

Journal Article

Noncutaneous Melanomas: A Single-Center Analysis

Del Prete, Valerio, Chaloupka, Karla, Holzmann, David, Fink, Daniel, Levesque, Mitchell, Dummer, Reinhard and Goldinger, Simone M. (2016). Noncutaneous Melanomas: A Single-Center Analysis. Dermatology, 232 (1), 22-29. doi: 10.1159/000441444

Noncutaneous Melanomas: A Single-Center Analysis

2016

Book Chapter

Cutaneous lymphomas

Goldinger, Simone M., Guenova, Emmanuella, Fujii, Kazuyasu and Urosevic-Maiwald, Mirjana (2016). Cutaneous lymphomas. Immunology of the Skin: Basic and Clinical Sciences in Skin Immune Responses. (pp. 463-475) Tokyo, Japan: Springer Japan. doi: 10.1007/978-4-431-55855-2_29

Cutaneous lymphomas

2015

Journal Article

Acquired <i>BRAF</i> inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms

Johnson, Douglas B., Menzies, Alexander M., Zimmer, Lisa, Eroglu, Zeynep, Ye, Fei, Zhao, Shilin, Rizos, Helen, Sucker, Antje, Scolyer, Richard A., Gutzmer, Ralf, Gogas, Helen, Kefford, Richard F., Thompson, John F., Becker, Juergen C., Berking, Carola, Egberts, Friederike, Loquai, Carmen, Goldinger, Simone M., Pupo, Gulietta M., Hugo, Willy, Kong, Xiangju, Garraway, Levi A., Sosman, Jeffrey A., Ribas, Antoni, Lo, Roger S., Long, Georgina V. and Schadendorf, Dirk (2015). Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms. European Journal of Cancer, 51 (18), 2792-2799. doi: 10.1016/j.ejca.2015.08.022

Acquired <i>BRAF</i> inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms

2015

Journal Article

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

Van Allen, Eliezer M., Miao, Diana, Schilling, Bastian, Shukla, Sachet A., Blank, Christian, Zimmer, Lisa, Sucker, Antje, Hillen, Uwe, Foppen, Marnix H. Geukes, Goldinger, Simone M., Utikal, Jochen, Hassel, Jessica C., Weide, Benjamin, Kaehler, Katharina C., Loquai, Carmen, Mohr, Peter, Gutzmer, Ralf, Dummer, Reinhard, Gabriel, Stacey, Wu, Catherine J., Schadendorf, Dirk and Garraway, Levi A. (2015). Genomic correlates of response to CTLA-4 blockade in metastatic melanoma. Science, 350 (6257), 207-211. doi: 10.1126/science.aad0095

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

2015

Journal Article

Analysis of BRAF and NRAS Mutation Status in Advanced Melanoma Patients Treated with Anti-CTLA-4 Antibodies: Association with Overall Survival?

Mangana, Joanna, Cheng, Phil F., Schindler, Katja, Weide, Benjamin, Held, Ulrike, Frauchiger, Anna L., Romano, Emanuella, Kaehler, Katharina C., Rozati, Sima, Rechsteiner, Markus, Moch, Holger, Michielin, Olivier, Garbe, Claus, Hauschild, Axel, Hoeller, Christoph, Dummer, Reinhard and Goldinger, Simone M. (2015). Analysis of BRAF and NRAS Mutation Status in Advanced Melanoma Patients Treated with Anti-CTLA-4 Antibodies: Association with Overall Survival?. Plos One, 10 (10) e0139438. doi: 10.1371/journal.pone.0139438

Analysis of BRAF and NRAS Mutation Status in Advanced Melanoma Patients Treated with Anti-CTLA-4 Antibodies: Association with Overall Survival?

2015

Journal Article

Histological evaluation of a "residual" metastasis after ipilimumab therapy in a patient with advanced melanoma

Matsushita, Shigeto, Kraehenbuehl, Lukas, Otsuka, Atsushi, Mihic-Probst, Daniela, Cheng, Phil, Dummer, Reinhard and Goldinger, Simone M. (2015). Histological evaluation of a "residual" metastasis after ipilimumab therapy in a patient with advanced melanoma. Journal of Dermatology, 42 (9), 927-928. doi: 10.1111/1346-8138.12964

Histological evaluation of a "residual" metastasis after ipilimumab therapy in a patient with advanced melanoma

2015

Journal Article

Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial

Ribas, Antoni, Puzanov, Igor, Dummer, Reinhard, Schadendorf, Dirk, Hamid, Omid, Robert, Caroline, Hodi, F. Stephen, Schachter, Jacob, Pavlick, Anna C., Lewis, Karl D., Cranmer, Lee D., Blank, Christian U., O'Day, Steven J., Ascierto, Paolo A., Salama, April K. S., Margolin, Kim A., Loquai, Carmen, Eigentler, Thomas K., Gangadhar, Tara C., Carlino, Matteo S., Agarwala, Sanjiv S., Moschos, Stergios J., Sosman, Jeffrey A., Goldinger, Simone M., Shapira-Frommer, Ronnie, Gonzalez, Rene, Kirkwood, John M., Wolchok, Jedd D., Eggermont, Alexander ... Daud, Adil (2015). Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial. Lancet Oncology, 16 (8), 908-918. doi: 10.1016/S1470-2045(15)00083-2

Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial

2015

Conference Publication

Radio Sensitization through BRAF Inhibitors- Mechanism and Frequency of Toxicities in Melanoma patients

Hecht, M., Zimmer, L., Loquai, C., Weishaupt, C., Gutzmer, R., Schuster, B., Gleisner, S., Schulze, B., Goldinger, S. M., Berking, C., Forschner, A., Clemens, P., Grabenbauer, G., Mueller-Brenne, T., Bauch, J., Eich, H. T., Grabbe, S., Schadendorf, D., Schuler, G., Keikavoussi, P., Semrau, S., Fietkau, R., Distel, L. V. and Heinzerling, L. (2015). Radio Sensitization through BRAF Inhibitors- Mechanism and Frequency of Toxicities in Melanoma patients. 21st Annual Meeting of the German-Society-for-Radiation-Oncology, Hamburg Germany, Jun 25-28, 2015. MUNICH: URBAN & VOGEL.

Radio Sensitization through BRAF Inhibitors- Mechanism and Frequency of Toxicities in Melanoma patients

2015

Journal Article

Radiosensitization by BRAF inhibitor therapy-mechanism and frequency of toxicity in melanoma patients

Hecht, M., Zimmer, L., Loquai, C., Weishaupt, C., Gutzmer, R., Schuster, B., Gleisner, S., Schulze, B., Goldinger, S. M., Berking, C., Forschner, A., Clemens, P., Grabenbauer, G., Mueller-Brenne, T., Bauch, J., Eich, H. T., Grabbe, S., Schadendorf, D., Schuler, G., Keikavoussi, P., Semrau, S., Fietkau, R., Distel, L. V. and Heinzerling, L. (2015). Radiosensitization by BRAF inhibitor therapy-mechanism and frequency of toxicity in melanoma patients. Annals of Oncology, 26 (6), 1238-1244. doi: 10.1093/annonc/mdv139

Radiosensitization by BRAF inhibitor therapy-mechanism and frequency of toxicity in melanoma patients

2015

Conference Publication

A multicenter, open label, phase II study to assess the efficacy and safety of APO866 in the treatment of patients with refractory or relapsed cutaneous T-cell lymphoma

Goldinger, Simone M., Gobbi, Sharon, Ding, Michelle, Frauchiger, Anna Lisa, Fink-Puches, Regina, Klemke, Claus-Detlev, Dreno, Brigitte, Bagot, Martine, Assaf, Chalid and Dummer, Reinhard (2015). A multicenter, open label, phase II study to assess the efficacy and safety of APO866 in the treatment of patients with refractory or relapsed cutaneous T-cell lymphoma. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, Chicago Il, May 29-Jun 02, 2015. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY.

A multicenter, open label, phase II study to assess the efficacy and safety of APO866 in the treatment of patients with refractory or relapsed cutaneous T-cell lymphoma

2015

Conference Publication

Real life experience with check point and kinase inhibitors in Swiss advanced melanoma patients

Goldinger, Simone M., Mangana, Joanna, Frauchiger, Anna L., Kaufmann, Corina, Held, Ulrike, Von Moos, Roger, Romano, Emanuela, Michielin, Olivier, Levesque, Mitchell Paul and Dummer, Reinhard (2015). Real life experience with check point and kinase inhibitors in Swiss advanced melanoma patients. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, Chicago Il, May 29-Jun 02, 2015. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY.

Real life experience with check point and kinase inhibitors in Swiss advanced melanoma patients

2015

Conference Publication

Association of PD-L1 expression in melanoma with response and prognosis to ipilimumab

Brueggemann, Caroline, Weide, Benjamin, Goldinger, Simone M., Konrad, Andreas, Erdmann, Michael, Schadendorf, Dirk, Croner, Roland S., Kraehenbuehl, Lukas, Kaehler, Katharina C., Hafner, Christian, Leisgang, Waltraud, Kiesewetter, Franklin, Dummer, Reinhard, Schuler, Gerold, Stuerzl, Michael and Heinzerling, Lucie (2015). Association of PD-L1 expression in melanoma with response and prognosis to ipilimumab. Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO) / Clinical Science Symposium on Predicting and Improving Adverse Outcomes in Older Adults with Cancer, Chicago Il, May 29-Jun 02, 2015. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY.

Association of PD-L1 expression in melanoma with response and prognosis to ipilimumab

2015

Conference Publication

Efficacy and safety of oral alitretinoin in oral mucosal lichen planus-results of a prospective trial

Kunz, Michael, Urosevic-Maiwald, Mirjana, Cozzio, Antonio, Dippel, Michaela, Dreier, Jil, French, Lars E., Goldinger, Simone, Guenova, Emmanuella, Jenni, Daniella, Kamarachev, Jivko, Mangana, Johanna and Dummer, Reinhard (2015). Efficacy and safety of oral alitretinoin in oral mucosal lichen planus-results of a prospective trial. NEW YORK: MOSBY-ELSEVIER.

Efficacy and safety of oral alitretinoin in oral mucosal lichen planus-results of a prospective trial