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2023

Journal Article

Activité des réanimations françaises à partir d’une base de données nationale entre 2013 et 2019 : une gravité en augmentation, mais des durées de séjour et un taux de mortalité en baisse

Boulet, Nicolas, Boussere, Amal, Mezzarobba, Myriam, Sofonea, Mircea T., Payen, Didier, Lipman, Jeffrey, Laupland, Kevin B., Rello, Jordi, Lefrant, Jean-Yves, Muller, Laurent, Roger, Claire, Pirracchio, Romain, Mura, Thibault and Boudemaghe, Thierry (2023). Activité des réanimations françaises à partir d’une base de données nationale entre 2013 et 2019 : une gravité en augmentation, mais des durées de séjour et un taux de mortalité en baisse. Anesthésie & Réanimation, 9 (5-6), 485-497. doi: 10.1016/j.anrea.2023.10.003

Activité des réanimations françaises à partir d’une base de données nationale entre 2013 et 2019 : une gravité en augmentation, mais des durées de séjour et un taux de mortalité en baisse

2023

Journal Article

Intensive Care Unit activity in France from the national database between 2013 and 2019: More critically ill patients, shorter stay and lower mortality rate

Boulet, Nicolas, Boussere, Amal, Mezzarobba, Myriam, Sofonea, Mircea T., Payen, Didier, Lipman, Jeffrey, Laupland, Kevin B., Rello, Jordi, Lefrant, Jean-Yves, Muller, Laurent, Roger, Claire, Pirracchio, Romain, Mura, Thibault and Boudemaghe, Thierry (2023). Intensive Care Unit activity in France from the national database between 2013 and 2019: More critically ill patients, shorter stay and lower mortality rate. Anaesthesia Critical Care and Pain Medicine, 42 (5) 101228, 1-8. doi: 10.1016/j.accpm.2023.101228

Intensive Care Unit activity in France from the national database between 2013 and 2019: More critically ill patients, shorter stay and lower mortality rate

2023

Journal Article

Peri-operative pharmacokinetics of cefazolin prophylaxis during valve replacement surgery

Alli, Ahmad, Paruk, Fathima, Roger, Claire, Lipman, Jeffrey, Calleemalay, Daren, Wallis, Steven C., Scribante, Juan, Richards, Guy A. and Roberts, Jason A. (2023). Peri-operative pharmacokinetics of cefazolin prophylaxis during valve replacement surgery. PLoS One, 18 (9) e0291425, 1-14. doi: 10.1371/journal.pone.0291425

Peri-operative pharmacokinetics of cefazolin prophylaxis during valve replacement surgery

2023

Journal Article

Diagnosing sepsis in the ICU: comparison of a gene expression signature to pre-existing biomarkers

Denny, Kerina J., Lea, Rodney A., Lindell-Innes, Ross, Haupt, Larisa M., Heffernan, Aaron J., Harvey, Nicholas R., Hughes, Oliver, Cao, Van T., Stuart, Janine, Paterson, David L., McNamara, John F., Ungerer, Jacobus P.J., Pretorius, Carel J., Griffiths, Lyn R. and Lipman, Jeffrey (2023). Diagnosing sepsis in the ICU: comparison of a gene expression signature to pre-existing biomarkers. Journal of Critical Care, 76 154286, 1-6. doi: 10.1016/j.jcrc.2023.154286

Diagnosing sepsis in the ICU: comparison of a gene expression signature to pre-existing biomarkers

2023

Journal Article

Differentiating infection, colonisation, and sterile inflammation in critical illness: the emerging role of host-response profiling

Jeffrey, Mark, Denny, Kerina J., Lipman, Jeffrey and Conway Morris, Andrew (2023). Differentiating infection, colonisation, and sterile inflammation in critical illness: the emerging role of host-response profiling. Intensive Care Medicine, 49 (7), 760-771. doi: 10.1007/s00134-023-07108-6

Differentiating infection, colonisation, and sterile inflammation in critical illness: the emerging role of host-response profiling

2023

Journal Article

Is the pharmacokinetics of first-line anti-TB drugs a cause of high mortality rates in TB patients admitted to the ICU? A non-compartmental pharmacokinetic analysis

Beraldi-Magalhaes, Francisco, Parker, Suzanne L., Sanches, Cristina, Garcia, Leandro Sousa, Souza Carvalho, Brenda Karoline, Costa, Amanda Araujo, Fachi, Mariana Millan, de Liz, Marcus Vinicius, de Souza, Alexandra Brito, Safe, Izabella Picinin, Pontarolo, Roberto, Wallis, Steven, Lipman, Jeffrey, Roberts, Jason A. and Cordeiro-Santos, Marcelo (2023). Is the pharmacokinetics of first-line anti-TB drugs a cause of high mortality rates in TB patients admitted to the ICU? A non-compartmental pharmacokinetic analysis. Tropical Medicine and Infectious Disease, 8 (6) 312, 1-10. doi: 10.3390/tropicalmed8060312

Is the pharmacokinetics of first-line anti-TB drugs a cause of high mortality rates in TB patients admitted to the ICU? A non-compartmental pharmacokinetic analysis

2023

Journal Article

Population pharmacokinetic study of Benzylpenicillin in critically unwell adults

Shah, Reya V., Kipper, Karin, Baker, Emma H., Barker, Charlotte I. S., Oldfield, Isobel, Philips, Barbara J., Johnston, Atholl, Lipman, Jeffrey, Rhodes, Andrew, Basarab, Marina, Sharland, Mike, Almahdi, Sarraa, Wake, Rachel M., Standing, Joseph F. and Lonsdale, Dagan O. (2023). Population pharmacokinetic study of Benzylpenicillin in critically unwell adults. Antibiotics, 12 (4) 643, 643. doi: 10.3390/antibiotics12040643

Population pharmacokinetic study of Benzylpenicillin in critically unwell adults

2023

Journal Article

Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes

Joynt, Gavin Matthew, Ling, Lowell, Wong, Wai Tat and Lipman, Jeffrey (2023). Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes. Expert Review of Clinical Pharmacology, 16 (8), 703-714. doi: 10.1080/17512433.2023.2194629

Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes

2023

Journal Article

Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients

Adiraju, Santosh K. S., Sumi, Chandra D., Pandey, Saurabh, Cotta, Menino O., Roberts, Jason A, Lipman, Jeffrey, Wallis, Steven C. and Parker, Suzanne L. (2023). Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients. Bioanalysis, 15 (1), 31-42. doi: 10.4155/bio-2022-0230

Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients

2023

Journal Article

Corrigendum to “Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis” [Crit Care Resusc 23(3) (2021) 273–284]

Billot, Laurent, Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino Osbert, Davis, Joshua S., Finfer, Simon, Hammond, Naomi, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Roger, Claire, Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman and Dulhunty, Joel M. (2023). Corrigendum to “Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis” [Crit Care Resusc 23(3) (2021) 273–284]. Critical Care and Resuscitation, 25 (1), 60-60. doi: 10.1016/j.ccrj.2023.04.012

Corrigendum to “Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis” [Crit Care Resusc 23(3) (2021) 273–284]

2023

Journal Article

A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study

Roberts, Jason A., Sime, Fekade, Lipman, Jeffrey, Hernández-Mitre, Maria Patricia, Baptista, João Pedro, Brüggemann, Roger J., Darvall, Jai, De Waele, Jan J., Dimopoulos, George, Lefrant, Jean-Yves, Mat Nor, Mohd Basri, Rello, Jordi, Seoane, Leonardo, Slavin, Monica A., Valkonen, Miia, Venditti, Mario, Wong, Wai Tat, Zeitlinger, Markus and Roger, Claire (2023). A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study. Critical Care and Resuscitation, 25 (1), 1-5. doi: 10.1016/j.ccrj.2023.04.002

A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study

2023

Journal Article

Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study

Tabah, Alexis, Buetti, Niccolò, Staiquly, Quentin, Ruckly, Stéphane, Akova, Murat, Aslan, Abdullah Tarik, Leone, Marc, Conway Morris, Andrew, Bassetti, Matteo, Arvaniti, Kostoula, Lipman, Jeffrey, Ferrer, Ricard, Qiu, Haibo, Paiva, José-Artur, Povoa, Pedro, De Bus, Liesbet, De Waele, Jan, Zand, Farid, Gurjar, Mohan, Alsisi, Adel, Abidi, Khalid, Bracht, Hendrik, Hayashi, Yoshiro, Jeon, Kyeongman, Elhadi, Muhammed, Barbier, François, Timsit, Jean-François, Tabah, Alexis, Pollock, Hamish ... Finnis, Mackenzie (2023). Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study. Intensive Care Medicine, 49 (2), 178-190. doi: 10.1007/s00134-022-06944-2

Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study

2023

Journal Article

Advancing precision-based antimicrobial dosing in critically ill patients

Cotta, Menino O., Lipman, Jeffrey and De Waele, Jan (2023). Advancing precision-based antimicrobial dosing in critically ill patients. Intensive Care Medicine, 49 (3), 324-326. doi: 10.1007/s00134-022-06969-7

Advancing precision-based antimicrobial dosing in critically ill patients

2022

Journal Article

Scoping review on diagnostic criteria and investigative approach in sepsis of unknown origin in critically ill patients

Ling, Lowell, Mui, Oliver Oi Yat, Laupland, Kevin B., Lefrant, Jean-Yves, Roberts, Jason A., Gopalan, Pragasan Dean, Lipman, Jeffrey, Joynt, Gavin M., Stelfox, Tom, Niven, Daniel, Paramalingam, Rameiya, Vonderhaar, Derek, Freebairn, Ross, Ling, Lowell, Leung, Patricia, Gopalan, Dean, Lefrant, Jean Yves, Lloret, Sophie, Elotmani, Loubna, Fourie, Cheryl, Saba, Renee, Carlisle, Dougal and Edwards, Felicity (2022). Scoping review on diagnostic criteria and investigative approach in sepsis of unknown origin in critically ill patients. Journal of Intensive Care, 10 (1) 44, 1-10. doi: 10.1186/s40560-022-00633-4

Scoping review on diagnostic criteria and investigative approach in sepsis of unknown origin in critically ill patients

2022

Journal Article

Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis

De Pascale, Gennaro, Antonelli, Massimo, Deschepper, Mieke, Arvaniti, Kostoula, Blot, Koen, Brown, Ben Creagh, de Lange, Dylan, De Waele, Jan, Dikmen, Yalim, Dimopoulos, George, Eckmann, Christian, Francois, Guy, Girardis, Massimo, Koulenti, Despoina, Labeau, Sonia, Lipman, Jeffrey, Lipovetsky, Fernando, Maseda, Emilio, Montravers, Philippe, Mikstacki, Adam, Paiva, José-Artur, Pereyra, Cecilia, Rello, Jordi, Timsit, Jean-Francois, Vogelaers, Dirk, Blot, Stijn, Lamrous, Amin, Lipovestky, Fernando, Rezende-Neto, Joao ... Davis, Noelle (2022). Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis. Intensive Care Medicine, 48 (11), 1593-1606. doi: 10.1007/s00134-022-06883-y

Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis

2022

Journal Article

A novel barrier device and method for protection against airborne pathogens during endotracheal intubation

Alonso, Julio M., Lipman, Jeffrey and Shekar, Kiran (2022). A novel barrier device and method for protection against airborne pathogens during endotracheal intubation. European Journal of Anaesthesiology, 39 (11), 900-903. doi: 10.1097/EJA.0000000000001731

A novel barrier device and method for protection against airborne pathogens during endotracheal intubation

2022

Journal Article

Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study

Buetti, Niccolò, Tabah, Alexis, Loiodice, Ambre, Ruckly, Stéphane, Aslan, Abdullah Tarik, Montrucchio, Giorgia, Cortegiani, Andrea, Saltoglu, Nese, Kayaaslan, Bircan, Aksoy, Firdevs, Murat, Akova, Akdoğan, Özlem, Saracoglu, Kemal Tolga, Erdogan, Cem, Leone, Marc, Ferrer, Ricard, Paiva, José-Artur, Hayashi, Yoshiro, Ramanan, Mahesh, Conway Morris, Andrew, Barbier, François, Timsit, Jean-François, Lipman, Jeffrey, Litton, Edward, Palermo, Anna Maria, Yap, Timothy, Eroglu, Ege, Hosokawa, Koji, Yoshida, Hideki ... Hamid, Hytham K. S. (2022). Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study. Critical Care, 26 (1) 319, 1-12. doi: 10.1186/s13054-022-04166-y

Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study

2022

Journal Article

Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients

Truong, Anh Quan, Dao, Xuan Co, Vu, Dinh Hoa, Nguyen, Hoang Anh, Do, Thi Hong Gam, Tran, Nhan Thang, Tran, Nhat Minh, Vu, Ngan Binh, Pham, Hong Nhung, Bui, Van Cuong, Trinh, The Anh, Dang, Quoc Tuan, Nguyen, Gia Binh, Lipman, Jeffrey, Cotta, Menino O. and Roberts, Jason A. (2022). Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients. Antimicrobial Agents and Chemotherapy, 66 (11) e0032122, 1-11. doi: 10.1128/aac.00321-22

Optimizing meropenem in highly resistant Klebsiella pneumoniae environments: population pharmacokinetics and dosing simulations in critically ill patients

2022

Journal Article

Laryngeal injury following endotracheal intubation: have you considered reflux?

Menon, Rahul, Vasani, Sarju S, Widdicombe, Neil J. and Lipman, Jeffrey (2022). Laryngeal injury following endotracheal intubation: have you considered reflux?. Anaesthesia and Intensive Care, 51 (1), 14-19. doi: 10.1177/0310057x221102472

Laryngeal injury following endotracheal intubation: have you considered reflux?

2022

Journal Article

Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs

Jager, Nynke G. L., Chai, Ming G., van Hest, Reiner M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2022). Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs. Clinical Microbiology and Infection, 28 (9) 1211, 1211-1224. doi: 10.1016/j.cmi.2022.03.041

Precision dosing software to optimize antimicrobial dosing: a systematic search and follow-up survey of available programs