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2019

Journal Article

Defining optimal dosing of ciprofloxacin in patients with septic shock

Roberts, Jason A., Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Sjövall, Fredrik (2019). Defining optimal dosing of ciprofloxacin in patients with septic shock. Journal of Antimicrobial Chemotherapy, 74 (6) dkz069, 1662-1669. doi: 10.1093/jac/dkz069

Defining optimal dosing of ciprofloxacin in patients with septic shock

2019

Journal Article

Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study

Guerra Valero, Yarmarly C., Roberts, Jason A., Lipman, Jeffrey, Fourie, Cheryl, Starr, Therese, Wallis, Steven C. and Parker, Suzanne L. (2019). Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study. Journal of Pharmaceutical and Biomedical Analysis, 169, 288-292. doi: 10.1016/j.jpba.2019.03.018

Analysis of capillary microsamples obtained from a skin-prick to measure vancomycin concentrations as a valid alternative to conventional sampling: a bridging study

2019

Journal Article

Antibiotic exposure at the site of infection: principles and assessment of tissue penetration

Jager, Nynke G. L., van Hest, Reinier M., Lipman, Jeffrey, Roberts, Jason A. and Cotta, Menino O. (2019). Antibiotic exposure at the site of infection: principles and assessment of tissue penetration. Expert Review of Clinical Pharmacology, 12 (7), 623-634. doi: 10.1080/17512433.2019.1621161

Antibiotic exposure at the site of infection: principles and assessment of tissue penetration

2019

Journal Article

The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence?

Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey and Rello, Jordi (2019). The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence?. European Journal of Clinical Microbiology & Infectious Diseases, 38 (4), 637-647. doi: 10.1007/s10096-019-03486-2

The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence?

2019

Journal Article

Correction to: The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence? (European Journal of Clinical Microbiology & Infectious Diseases, (2019), 10.1007/s10096-019-03486-2)

Koulenti, Despoina, Parisella, Francesca Romana, Xu, Elena, Lipman, Jeffrey and Rello, Jordi (2019). Correction to: The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence? (European Journal of Clinical Microbiology & Infectious Diseases, (2019), 10.1007/s10096-019-03486-2). European Journal of Clinical Microbiology and Infectious Diseases, 38 (4), 649-649. doi: 10.1007/s10096-019-03518-x

Correction to: The relationship between ventilator-associated pneumonia and chronic obstructive pulmonary disease: what is the current evidence? (European Journal of Clinical Microbiology & Infectious Diseases, (2019), 10.1007/s10096-019-03486-2)

2019

Journal Article

Challenges in the management of septic shock: a narrative review

De Backer, Daniel, Cecconi, Maurizio, Lipman, Jeffrey, Machado, Flavia, Myatra, Sheila Nainan, Ostermann, Marlies, Perner, Anders, Teboul, Jean-Louis, Vincent, Jean-Louis and Walley, Keith R. (2019). Challenges in the management of septic shock: a narrative review. Intensive Care Medicine, 45 (4), 420-433. doi: 10.1007/s00134-019-05544-x

Challenges in the management of septic shock: a narrative review

2019

Journal Article

Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review

Heffernan, Aaron J., Sime, Fekade B., Lipman, Jeffrey, Dhanani, Jayesh, Andrews, Katherine, Ellwood, David, Grimwood, Keith and Roberts, Jason A. (2019). Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review. International Journal of Antimicrobial Agents, 53 (3), 234-245. doi: 10.1016/j.ijantimicag.2018.11.011

Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review

2019

Journal Article

A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III

Lipman, Jeffrey, Brett, Stephen J., De Waele, Jan J., Cotta, Menino O., Davis, Joshua S., Finfer, Simon, Glass, Parisa, Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Billot, Laurent and Dulhunty, Joel M. (2019). A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III. Critical Care and Resuscitation, 21 (1), 63-68. doi: 10.1016/s1441-2772(23)00582-3

A protocol for a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis: BLING III

2019

Journal Article

Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis

Abraham, Jacob, Sinnollareddy, Mahipal G., Roberts, Michael S., Williams, Patricia, Peake, Sandra L., Lipman, Jeffrey and Roberts, Jason A. (2019). Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 53 (2), 137-142. doi: 10.1016/j.ijantimicag.2018.09.021

Plasma and interstitial fluid population pharmacokinetics of vancomycin in critically ill patients with sepsis

2019

Journal Article

Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models

Dhaese, Sofie A. M., Farkas, Andras, Colin, Pieter, Lipman, Jeffrey, Stove, Veronique, Verstraete, Alain G., Roberts, Jason A. and De Waele, Jan J. (2019). Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models. Journal of Antimicrobial Chemotherapy, 74 (2), 432-441. doi: 10.1093/jac/dky434

Population pharmacokinetics and evaluation of the predictive performance of pharmacokinetic models in critically ill patients receiving continuous infusion meropenem: a comparison of eight pharmacokinetic models

2019

Journal Article

Infections by multidrug-resistant gram-negative bacteria: what's new in our arsenal and what's in the pipeline?

Koulenti, Despoina, Song, Andrew, Ellingboe, Aaron, Abdul-Aziz, Mohd Hafiz, Harris, Patrick, Gavey, Emile and Lipman, Jeffrey (2019). Infections by multidrug-resistant gram-negative bacteria: what's new in our arsenal and what's in the pipeline?. International Journal of Antimicrobial Agents, 53 (3), 211-224. doi: 10.1016/j.ijantimicag.2018.10.011

Infections by multidrug-resistant gram-negative bacteria: what's new in our arsenal and what's in the pipeline?

2018

Journal Article

The statistical curriculum within randomized controlled trials in critical illness

McCullough, James P.A., Lipman, Jeffrey and Presneill, Jeffrey J. (2018). The statistical curriculum within randomized controlled trials in critical illness. Critical Care Medicine, 46 (12), 1985-1990. doi: 10.1097/CCM.0000000000003380

The statistical curriculum within randomized controlled trials in critical illness

2018

Journal Article

Sepsis in intensive care unit patients: worldwide data from the intensive care over nations audit

Sakr, Yasser, Jaschinski, Ulrich, Wittebole, Xavier, Szakmany, Tamas, Lipman, Jeffrey, Namendys-Silva, Silvio A., Martin-Loeches, Ignacio, Leone, Marc, Lupu, Mary-Nicoleta and Vincent, Jean-Louis (2018). Sepsis in intensive care unit patients: worldwide data from the intensive care over nations audit. Open Forum Infectious Diseases, 5 (12), ofy313. doi: 10.1093/ofid/ofy313

Sepsis in intensive care unit patients: worldwide data from the intensive care over nations audit

2018

Journal Article

A comparison between raw and predicted mortality in a paediatric intensive care unit in South Africa

Ballot, Daynia Elizabeth, Ramdin, Tanusha, White, Debbie Ann and Lipman, Jeffrey (2018). A comparison between raw and predicted mortality in a paediatric intensive care unit in South Africa. BMC Research Notes, 11 (1) 829, 829. doi: 10.1186/s13104-018-3946-9

A comparison between raw and predicted mortality in a paediatric intensive care unit in South Africa

2018

Journal Article

A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminemia receiving continuous venovenous hemodiafiltration

Sime, Fekade B., Stuart, Janine, Butler, Jenie, Starr, Therese, Wallis, Steven C., Pandey, Saurabh, Lipman, Jeffrey and Roberts, Jason A. (2018). A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminemia receiving continuous venovenous hemodiafiltration. International Journal of Antimicrobial Agents, 52 (4), 506-509. doi: 10.1016/j.ijantimicag.2018.07.008

A pharmacokinetic case study of intravenous posaconazole in a critically ill patient with hypoalbuminemia receiving continuous venovenous hemodiafiltration

2018

Journal Article

Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures

Wong, Gloria, Briscoe, Scott, McWhinney, Brett, Ally, Mumtaz, Ungerer, Jacobus, Lipman, Jeffrey and Roberts, Jason A (2018). Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures. Journal of Antimicrobial Chemotherapy, 73 (11), 3087-3094. doi: 10.1093/jac/dky314

Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures

2018

Journal Article

Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam

Sime, Fekade B., Pandey, Saurabh, Karamujic, Nermin, Parker, Suzanne, Alexander, Elizabeth, Loutit, Jeffery, Durso, Stephanie, Griffith, David, Lipman, Jeffrey, Wallis, Steven C. and Roberts, Jason A. (2018). Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam. Antimicrobial Agents and Chemotherapy, 62 (10) e01306, AAC.01306-18. doi: 10.1128/AAC.01306-18

Ex vivo characterisation of effects of renal replacement therapy modalities and settings on pharmacokinetics of meropenem and vaborbactam

2018

Journal Article

A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models

Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F. and Roberts, Jason A. (2018). A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models. Intensive Care Medicine Experimental, 6 (1) 17, 17. doi: 10.1186/s40635-018-0180-7

A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models

2018

Journal Article

Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions

Dhanani, Jayesh A., Parker, Suzanne L., Lipman, Jeffrey, Wallis, Steven C., Cohen, Jeremy, Fraser, John, Barnett, Adrian, Chew, Michelle and Roberts, Jason A. (2018). Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions. Journal of Pharmaceutical Analysis, 8 (6), 407-412. doi: 10.1016/j.jpha.2018.07.003

Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions

2018

Journal Article

The authors reply

Rhodes, Nathaniel J., Liu, Jiajun, Lipman, Jeffrey and Roberts, Jason A. (2018). The authors reply. Critical Care Medicine, 46 (7), e725-e726. doi: 10.1097/CCM.0000000000003164

The authors reply