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2017

Journal Article

The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibiotics

Udy, Andrew A, Roberts, Jason A, Lipman, Jeffrey and Blot, Stijn (2017). The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibiotics. Advanced drug delivery reviews, 123, 65-74. doi: 10.1016/j.addr.2017.09.019

The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibiotics

2017

Journal Article

Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?

Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey and Cotta, Menino Osbert (2017). Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?. Clinical Pharmacokinetics, 57 (4), 439-454. doi: 10.1007/s40262-017-0588-3

Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?

2017

Journal Article

Maximally effective dosing regimens of meropenem in patients with septic shock

Sjövall, Fredrik, Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Roberts, Jason A. (2017). Maximally effective dosing regimens of meropenem in patients with septic shock. The Journal of Antimicrobial Chemotherapy, 73 (1) dkx330, 191-198. doi: 10.1093/jac/dkx330

Maximally effective dosing regimens of meropenem in patients with septic shock

2017

Journal Article

Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients

Roger, Claire, Cotta, Menino O., Muller, Laurent, Wallis, Steven C., Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2017). Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients. International Journal of Antimicrobial Agents, 50 (2), 227-231. doi: 10.1016/j.ijantimicag.2017.03.018

Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients

2017

Journal Article

Population pharmacokinetics of tigecycline in critically ill patients with severe infections

Xie, Jiao, Roberts, Jason A., Alobaid, Abdulaziz S., Roger, Claire, Wang, Yan, Yang, Qianting, Sun, Jinyao, Dong, Haiyan, Wang, Xue, Xing, Jianfeng, Lipman, Jeffrey and Dong, Yalin (2017). Population pharmacokinetics of tigecycline in critically ill patients with severe infections. Antimicrobial Agents and Chemotherapy, 61 (8) e00345-17, e00345-17. doi: 10.1128/AAC.00345-17

Population pharmacokinetics of tigecycline in critically ill patients with severe infections

2017

Journal Article

Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition

Harris, P.N.A., McNamara, J.F., Lye, D.C., Davis, J.S., Bernard, L., Cheng, A.C., Doi, Y., Fowler, V.G., Kaye, K.S., Leibovici, L., Lipman, J., Llewelyn, M.J., Munoz-Price, S., Paul, M., Peleg, A.Y., Rodriguez-Bano, J., Rogers, B.A., Seifert, H., Thamlikitkul, V., Thwaites, G., Tong, S.Y.C., Turnidge, J., Utili, R., Webb, S.A.R. and Paterson, D.L. (2017). Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition. Clinical Microbiology and Infection, 23 (8), 533-541. doi: 10.1016/j.cmi.2016.10.023

Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition

2017

Journal Article

Detailed assessment of benefits and risks of retrievable inferior vena cava filters on patients with complicated injuries: the da Vinci multicentre randomised controlled trial study protocol

Ho, Kwok M., Rao, Sudhakar, Honeybul, Stephen, Zellweger, Rene, Wibrow, Bradley, Lipman, Jeffrey, Holley, Anthony, Kop, Alan, Geelhoed, Elizabeth and Corcoran, Tomas (2017). Detailed assessment of benefits and risks of retrievable inferior vena cava filters on patients with complicated injuries: the da Vinci multicentre randomised controlled trial study protocol. Bmj Open, 7 (7) e016747, e016747. doi: 10.1136/bmjopen-2017-016747

Detailed assessment of benefits and risks of retrievable inferior vena cava filters on patients with complicated injuries: the da Vinci multicentre randomised controlled trial study protocol

2017

Journal Article

Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international survey

Badenes, Rafael, Oddo, Mauro, Suarez, Jose I., Antonelli, Massimo, Lipman, Jeffrey, Citerio, Giuseppe and Taccone, Fabio Silvio (2017). Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international survey. Critical Care, 21 (1) 159, 159. doi: 10.1186/s13054-017-1748-4

Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international survey

2017

Journal Article

Factors influencing psychological, social and health outcomes after major burn injuries in adults: cohort study protocol

Druery, Martha, Newcombe, Peter A., Cameron, Cate M. and Lipman, Jeffrey (2017). Factors influencing psychological, social and health outcomes after major burn injuries in adults: cohort study protocol. BMJ Open, 7 (6) e017545, e017545. doi: 10.1136/bmjopen-2017-017545

Factors influencing psychological, social and health outcomes after major burn injuries in adults: cohort study protocol

2017

Journal Article

An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent

Parker, Suzanne L., Valero, Yarmarly C. Guerra, Mejia, Jenny L. Ordonez, Roger, Claire, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2017). An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent. Bioanalysis, 9 (12), 911-924. doi: 10.4155/bio-2017-0019

An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent

2017

Journal Article

Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial

Naik, B. I., Roger, C., Ikeda, K., Todorovic, M. S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2017). Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial. British Journal of Anaesthesia, 118 (6), 876-882. doi: 10.1093/bja/aex026

Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial

2017

Journal Article

Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy

Economou, Caleb J. P., Wong, Gloria, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2017). Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy. International Journal of Antimicrobial Agents, 49 (5), 589-594. doi: 10.1016/j.ijantimicag.2017.01.009

Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy

2017

Journal Article

Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model

Bergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2017). Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model. Antimicrobial Agents and Chemotherapy, 61 (5) e02642, e02642-16. doi: 10.1128/AAC.02642-16

Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model

2017

Journal Article

“Salvage treatment” for infections by extensively- and pan-drug-resistant pathogens is common and often sub-optimal

Poulakou, Garyfallia, Matthaiou, Dimitrios K., Bassetti, Matteo, Erdem, Hakan, Dimopoulos, George, Curcio, Daniel J., Carlet, Jean, Lipman, Jeffrey, Timsit, Jean‑François, Giamarellou, Helen, Arfaras-Melainis, Angelos and Rello, Jordi (2017). “Salvage treatment” for infections by extensively- and pan-drug-resistant pathogens is common and often sub-optimal. Intensive Care Medicine, 43 (8), 1164-1166. doi: 10.1007/s00134-017-4796-y

“Salvage treatment” for infections by extensively- and pan-drug-resistant pathogens is common and often sub-optimal

2017

Journal Article

What’s new in pharmacokinetics of antimicrobials in AKI and RRT?

Roberts, Jason A., Lefrant, Jean-Yves and Lipman, Jeffrey (2017). What’s new in pharmacokinetics of antimicrobials in AKI and RRT?. Intensive Care Medicine, 43 (6), 1-3. doi: 10.1007/s00134-017-4789-x

What’s new in pharmacokinetics of antimicrobials in AKI and RRT?

2017

Journal Article

Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial

Udy, Andrew A., Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K. and Lipman, Jeffrey (2017). Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial. International Journal of Antimicrobial Agents, 49 (5), 624-630. doi: 10.1016/j.ijantimicag.2016.12.022

Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial

2017

Journal Article

Pyroglutamate (5-oxoproline) measured with hydrophilic interaction chromatography (HILIC) tandem mass spectrometry in acutely ill patients

Pretorius, Carel J., Reade, Michael C., Warnholtz, Chris, McWhinney, Brett, Phua, Meng Mei, Lipman, Jeffrey and Ungerer, Jacobus P. J. (2017). Pyroglutamate (5-oxoproline) measured with hydrophilic interaction chromatography (HILIC) tandem mass spectrometry in acutely ill patients. Clinica Chimica Acta, 466, 72-77. doi: 10.1016/j.cca.2017.01.012

Pyroglutamate (5-oxoproline) measured with hydrophilic interaction chromatography (HILIC) tandem mass spectrometry in acutely ill patients

2017

Journal Article

Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients

Alobaid, Abdulaziz S., Wallis, Steven C., Jarrett, Paul, Starr, Therese, Stuart, Janine, Lassig-Smith, Melissa, Mejia, Jenny Lisette Ordóñez, Roberts, Michael S., Roger, Claire, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2017). Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients. Antimicrobial Agents and Chemotherapy, 61 (3) e01276, e01276-16. doi: 10.1128/AAC.01276-16

Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients

2017

Journal Article

Systemic inflammatory response syndrome, quick sequential organ function assessment, and organ dysfunction: insights from a prospective database of ED patients with infection

Williams, Julian M., Greenslade, Jaimi H., McKenzie, Juliet V., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffrey (2017). Systemic inflammatory response syndrome, quick sequential organ function assessment, and organ dysfunction: insights from a prospective database of ED patients with infection. Chest, 151 (3), 586-596. doi: 10.1016/j.chest.2016.10.057

Systemic inflammatory response syndrome, quick sequential organ function assessment, and organ dysfunction: insights from a prospective database of ED patients with infection

2017

Journal Article

Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review

Paruk, Fathima, Sime, Fekade B., Lipman, Jeffrey and Roberts, Jason A. (2017). Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review. International Journal of Antimicrobial Agents, 49 (4), 395-402. doi: 10.1016/j.ijantimicag.2016.12.014

Dosing antibiotic prophylaxis during cardiopulmonary bypass—a higher level of complexity? A structured review