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2017 Journal Article A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samplesParker, Suzanne L., Guerra Valero, Yarmarly C., Lipman, Jeffrey, Weiss, Steven, Smith, Camilla, Russell, Lyndal, Smith, Paul, Roberts, Jason A and Wallis, Steven C (2017). A validated UHPLC-MS/MS method for the measurement of riluzole in plasma and myocardial tissue samples. Biomedical Chromatography, 31 (12) e4030, e4030. doi: 10.1002/bmc.4030 |
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2017 Journal Article Identifying "at-risk" patients for sub-optimal beta-lactam exposure in critically ill patients with severe infectionsAbdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2017). Identifying "at-risk" patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections. Critical Care, 21 (1) 283, 1-3. doi: 10.1186/s13054-017-1871-2 |
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2017 Journal Article Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropeniaSime, Fekade Bruck, Hahn, Uwe, Warner, Morgyn S., Tiong, Ing Soo, Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2017). Using population pharmacokinetic modeling and Monte Carlo simulations to determine whether standard doses of piperacillin in piperacillin-tazobactam regimens are adequate for the management of febrile neutropenia. Antimicrobial Agents and Chemotherapy, 61 (11) e00311-17, e00311-17. doi: 10.1128/AAC.00311-17 |
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2017 Journal Article Therapeutic targets in necrotizing soft tissue infectionsde Prost, Nicholas, Lipman, Jeffrey and Mimoz, Olivier (2017). Therapeutic targets in necrotizing soft tissue infections. Intensive Care Medicine, 43 (11), 1717-1719. doi: 10.1007/s00134-017-4813-1 |
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2017 Journal Article The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibioticsUdy, Andrew A, Roberts, Jason A, Lipman, Jeffrey and Blot, Stijn (2017). The effects of major burn related pathophysiological changes on the pharmacokinetics and pharmacodynamics of drug use: An appraisal utilizing antibiotics. Advanced drug delivery reviews, 123, 65-74. doi: 10.1016/j.addr.2017.09.019 |
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2017 Journal Article Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?Kumta, Nilesh, Roberts, Jason A., Lipman, Jeffrey and Cotta, Menino Osbert (2017). Antibiotic distribution into cerebrospinal fluid: can dosing safely account for drug and disease factors in the treatment of ventriculostomy-associated infections?. Clinical Pharmacokinetics, 57 (4), 439-454. doi: 10.1007/s40262-017-0588-3 |
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2017 Journal Article Maximally effective dosing regimens of meropenem in patients with septic shockSjövall, Fredrik, Alobaid, Abdulaziz S., Wallis, Steven C., Perner, Anders, Lipman, Jeffrey and Roberts, Jason A. (2017). Maximally effective dosing regimens of meropenem in patients with septic shock. The Journal of Antimicrobial Chemotherapy, 73 (1) dkx330, 191-198. doi: 10.1093/jac/dkx330 |
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2017 Journal Article Population pharmacokinetics of tigecycline in critically ill patients with severe infectionsXie, Jiao, Roberts, Jason A., Alobaid, Abdulaziz S., Roger, Claire, Wang, Yan, Yang, Qianting, Sun, Jinyao, Dong, Haiyan, Wang, Xue, Xing, Jianfeng, Lipman, Jeffrey and Dong, Yalin (2017). Population pharmacokinetics of tigecycline in critically ill patients with severe infections. Antimicrobial Agents and Chemotherapy, 61 (8) e00345-17, e00345-17. doi: 10.1128/AAC.00345-17 |
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2017 Journal Article Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definitionHarris, P.N.A., McNamara, J.F., Lye, D.C., Davis, J.S., Bernard, L., Cheng, A.C., Doi, Y., Fowler, V.G., Kaye, K.S., Leibovici, L., Lipman, J., Llewelyn, M.J., Munoz-Price, S., Paul, M., Peleg, A.Y., Rodriguez-Bano, J., Rogers, B.A., Seifert, H., Thamlikitkul, V., Thwaites, G., Tong, S.Y.C., Turnidge, J., Utili, R., Webb, S.A.R. and Paterson, D.L. (2017). Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition. Clinical Microbiology and Infection, 23 (8), 533-541. doi: 10.1016/j.cmi.2016.10.023 |
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2017 Journal Article Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patientsRoger, Claire, Cotta, Menino O., Muller, Laurent, Wallis, Steven C., Lipman, Jeffrey, Lefrant, Jean-Yves and Roberts, Jason A. (2017). Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients. International Journal of Antimicrobial Agents, 50 (2), 227-231. doi: 10.1016/j.ijantimicag.2017.03.018 |
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2017 Journal Article Detailed assessment of benefits and risks of retrievable inferior vena cava filters on patients with complicated injuries: the da Vinci multicentre randomised controlled trial study protocolHo, Kwok M., Rao, Sudhakar, Honeybul, Stephen, Zellweger, Rene, Wibrow, Bradley, Lipman, Jeffrey, Holley, Anthony, Kop, Alan, Geelhoed, Elizabeth and Corcoran, Tomas (2017). Detailed assessment of benefits and risks of retrievable inferior vena cava filters on patients with complicated injuries: the da Vinci multicentre randomised controlled trial study protocol. Bmj Open, 7 (7) e016747, e016747. doi: 10.1136/bmjopen-2017-016747 |
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2017 Journal Article Factors influencing psychological, social and health outcomes after major burn injuries in adults: cohort study protocolDruery, Martha, Newcombe, Peter A., Cameron, Cate M. and Lipman, Jeffrey (2017). Factors influencing psychological, social and health outcomes after major burn injuries in adults: cohort study protocol. BMJ Open, 7 (6) e017545, e017545. doi: 10.1136/bmjopen-2017-017545 |
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2017 Journal Article Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international surveyBadenes, Rafael, Oddo, Mauro, Suarez, Jose I., Antonelli, Massimo, Lipman, Jeffrey, Citerio, Giuseppe and Taccone, Fabio Silvio (2017). Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international survey. Critical Care, 21 (1) 159, 159. doi: 10.1186/s13054-017-1748-4 |
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2017 Journal Article Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trialNaik, B. I., Roger, C., Ikeda, K., Todorovic, M. S., Wallis, S. C., Lipman, J. and Roberts, J. A. (2017). Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial. British Journal of Anaesthesia, 118 (6), 876-882. doi: 10.1093/bja/aex026 |
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2017 Journal Article An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluentParker, Suzanne L., Valero, Yarmarly C. Guerra, Mejia, Jenny L. Ordonez, Roger, Claire, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2017). An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent. Bioanalysis, 9 (12), 911-924. doi: 10.4155/bio-2017-0019 |
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2017 Journal Article Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapyEconomou, Caleb J. P., Wong, Gloria, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2017). Impact of β-lactam antibiotic therapeutic drug monitoring on dose adjustments in critically ill patients undergoing continuous renal replacement therapy. International Journal of Antimicrobial Agents, 49 (5), 589-594. doi: 10.1016/j.ijantimicag.2017.01.009 |
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2017 Journal Article Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection modelBergen, Phillip J., Bulitta, Jurgen B., Kirkpatrick, Carl M. J., Rogers, Kate E., McGregor, Megan J., Wallis, Steven C., Paterson, David L., Nation, Roger L., Lipman, Jeffrey, Roberts, Jason A. and Landersdorfer, Cornelia B. (2017). Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model. Antimicrobial Agents and Chemotherapy, 61 (5) e02642, e02642-16. doi: 10.1128/AAC.02642-16 |
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2017 Journal Article “Salvage treatment” for infections by extensively- and pan-drug-resistant pathogens is common and often sub-optimalPoulakou, Garyfallia, Matthaiou, Dimitrios K., Bassetti, Matteo, Erdem, Hakan, Dimopoulos, George, Curcio, Daniel J., Carlet, Jean, Lipman, Jeffrey, Timsit, Jean‑François, Giamarellou, Helen, Arfaras-Melainis, Angelos and Rello, Jordi (2017). “Salvage treatment” for infections by extensively- and pan-drug-resistant pathogens is common and often sub-optimal. Intensive Care Medicine, 43 (8), 1164-1166. doi: 10.1007/s00134-017-4796-y |
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2017 Journal Article What’s new in pharmacokinetics of antimicrobials in AKI and RRT?Roberts, Jason A., Lefrant, Jean-Yves and Lipman, Jeffrey (2017). What’s new in pharmacokinetics of antimicrobials in AKI and RRT?. Intensive Care Medicine, 43 (6), 1-3. doi: 10.1007/s00134-017-4789-x |
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2017 Journal Article Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trialUdy, Andrew A., Dulhunty, Joel M., Roberts, Jason A., Davis, Joshua S., Webb, Steven A. R., Bellomo, Rinaldo, Gomersall, Charles, Shirwadkar, Charudatt, Eastwood, Glenn M., Myburgh, John, Paterson, David L., Starr, Therese, Paul, Sanjoy K. and Lipman, Jeffrey (2017). Association between augmented renal clearance and clinical outcomes in patients receiving β-lactam antibiotic therapy by continuous or intermittent infusion: a nested cohort study of the BLING-II randomised, placebo-controlled, clinical trial. International Journal of Antimicrobial Agents, 49 (5), 624-630. doi: 10.1016/j.ijantimicag.2016.12.022 |