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2020 Journal Article A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studiesParker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Stuart, Janine, Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2020). A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane–tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies. Clinical Chemistry and Laboratory Medicine (CCLM), 59 (5), 921-933. doi: 10.1515/cclm-2020-1196 |
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2020 Journal Article Vancomycin serum concentration after 48 h of administration: A 3-years survey in an intensive care unitPerin, Nicolas, Roger, Claire, Marin, Grégory, Molinari, Nicolas, Evrard, Alexandre, Lavigne, Jean-Philippe, Barbar, Saber, Claret, Pierre Géraud, Boutin, Caroline, Muller, Laurent, Lipman, Jeffrey, Lefrant, Jean-Yves, Jaber, Samir and Roberts, Jason A. (2020). Vancomycin serum concentration after 48 h of administration: A 3-years survey in an intensive care unit. Antibiotics, 9 (11) 793, 1-16. doi: 10.3390/antibiotics9110793 |
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2020 Journal Article Ceftriaxone dosing in patients admitted from the emergency department with sepsisHeffernan, Aaron J., Curran, Rebecca A., Denny, Kerina J., Sime, Fekade B., Stanford, Claire L., McWhinney, Brett, Ungerer, Jacobus, Roberts, Jason A. and Lipman, Jeffrey (2020). Ceftriaxone dosing in patients admitted from the emergency department with sepsis. European Journal of Clinical Pharmacology, 77 (2), 207-214. doi: 10.1007/s00228-020-03001-z |
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2020 Journal Article Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuitEconomou, Caleb J. P., Ordoñez, Jennifer, Wallis, Steven C., Richards, Brent, McWhinney, Brett, Lipman, Jeffrey and Roberts, Jason A. (2020). Ticarcillin and piperacillin adsorption on to polyethersulfone haemodiafilter membranes in an ex-vivo circuit. International Journal of Antimicrobial Agents, 56 (3) 106058, 1-5. doi: 10.1016/j.ijantimicag.2020.106058 |
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2020 Journal Article Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniaeSumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Islam, Kamrul, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2020). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae. Journal of Antimicrobial Chemotherapy, 75 (9), 2633-2640. doi: 10.1093/jac/dkaa211 |
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2020 Journal Article The importance of airway and lung microbiome in the critically illMartin-Loeches, Ignacio, Dickson, Robert, Torres, Antoni, Hanberger, Håkan, Lipman, Jeffrey, Antonelli, Massimo, de Pascale, Gennaro, Bozza, Fernando, Vincent, Jean Louis, Murthy, Srinivas, Bauer, Michael, Marshall, John, Cilloniz, Catia and Bos, Lieuwe D. (2020). The importance of airway and lung microbiome in the critically ill. Critical care, 24 (1) 537, 537. doi: 10.1186/s13054-020-03219-4 |
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2020 Journal Article International facilitators and barriers to family engagement in the ICU: Results of a qualitative analysisHamilton, Rebekah, Kleinpell, Ruth, Lipman, Jeffrey and Davidson, Judy E. (2020). International facilitators and barriers to family engagement in the ICU: Results of a qualitative analysis. Journal of Critical Care, 58, 72-77. doi: 10.1016/j.jcrc.2020.04.011 |
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2020 Journal Article Mineralocorticoid dysfunction during critical illness: a review of the evidenceNethathe, Gladness Dakalo, Cohen, Jeremy, Lipman, Jeffrey, Anderson, Ronald and Feldman, Charles (2020). Mineralocorticoid dysfunction during critical illness: a review of the evidence. Anesthesiology, 133 (2), 439-457. doi: 10.1097/ALN.0000000000003365 |
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2020 Journal Article Quality of evidence supporting surviving sepsis campaign recommendationsRello, Jordi, Tejada, Sofia, Xu, Elena, Solé-Lleonart, Candela, Campogiani, Laura, Koulenti, Despoina, Ferreira-Coimbra, João and Lipman, Jeff (2020). Quality of evidence supporting surviving sepsis campaign recommendations. Anaesthesia Critical Care and Pain Medicine, 39 (4), 497-502. doi: 10.1016/j.accpm.2020.06.015 |
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2020 Journal Article Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection modelsDhaese, Sofie, Heffernan, Aaron, Liu, David, Abdul-Aziz, Mohd Hafiz, Stove, Veronique, Tam, Vincent H., Lipman, Jeffrey, Roberts, Jason A. and De Waele, Jan J. (2020). Prolonged versus intermittent infusion of β-Lactam antibiotics: a systematic review and meta-regression of bacterial killing in preclinical infection models. Clinical Pharmacokinetics, 59 (10), 1237-1250. doi: 10.1007/s40262-020-00919-6 |
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2020 Journal Article Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection modelHeffernan, Aaron J., Sime, Fekade B., Sarovich, Derek S., Neely, Michael, Guerra-Valero, Yarmarly, Naicker, Saiyuri, Cottrell, Kyra, Harris, Patrick, Andrews, Katherine T., Ellwood, David, Wallis, Steven C., Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2020). Pharmacodynamic evaluation of plasma and epithelial lining fluid exposures of amikacin against in a dynamic hollow-fibre infection model. Antimicrobial Agents and Chemotherapy, 64 (9) e00879-20. doi: 10.1128/aac.00879-20 |
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2020 Journal Article Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep modelDhanani, Jayesh A., Ahern, Benjamin, Lupinsky, Liad, Jackson, Karen, Wallis, Steven C., Abdul-Aziz, Mohd H., Lipman, Jeffrey and Roberts, Jason A. (2020). Comparative plasma pharmacokinetics of ceftriaxone and ertapenem between normoalbuminemia, hypoalbuminemia and with albumin replacement in a sheep model. Antimicrobial Agents and Chemotherapy, 64 (7) e02584-19. doi: 10.1128/aac.02584-19 |
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2020 Journal Article Conventional pig as animal model for human renal drug excretion processes: unravelling the porcine renal function by use of a cocktail of exogenous markersDhondt, Laura, Croubels, Siska, De Paepe, Peter, Wallis, Steven C., Pandey, Saurabh, Roberts, Jason A., Lipman, Jeffrey, De Cock, Pieter and Devreese, Mathias (2020). Conventional pig as animal model for human renal drug excretion processes: unravelling the porcine renal function by use of a cocktail of exogenous markers. Frontiers in Pharmacology, 11 883, 883. doi: 10.3389/fphar.2020.00883 |
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2020 Journal Article Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA studyDe Bus, Liesbet, Depuydt, Pieter, Steen, Johan, Dhaese, Sofie, De Smet, Ken, Tabah, Alexis, Akova, Murat, Cotta, Menino Osbert, De Pascale, Gennaro, Dimopoulos, George, Fujitani, Shigeki, Garnacho-Montero, Jose, Leone, Marc, Lipman, Jeffrey, Ostermann, Marlies, Paiva, José-Artur, Schouten, Jeroen, Sjövall, Fredrik, Timsit, Jean-François, Roberts, Jason A., Zahar, Jean-Ralph, Zand, Farid, Zirpe, Kapil, De Waele, Jan J. and DIANA study group (2020). Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study. Intensive Care Medicine, 46 (7), 1404-1417. doi: 10.1007/s00134-020-06111-5 |
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2020 Journal Article Optimization of flucloxacillin dosing regimens in critically ill patients using population pharmacokinetic modelling of total and unbound concentrationsJager, Nynke G. L., van Hest, Reinier M., Xie, Jiao, Wong, Gloria, Ulldemolins, Marta, Brüggemann, Roger J. M., Lipman, Jeffrey and Roberts, Jason A. (2020). Optimization of flucloxacillin dosing regimens in critically ill patients using population pharmacokinetic modelling of total and unbound concentrations. Journal of Antimicrobial Chemotherapy, 75 (9), 2641-2649. doi: 10.1093/jac/dkaa187 |
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2020 Journal Article An Integrated Dialysis Pharmacometric (IDP) model to evaluate the pharmacokinetics in patients undergoing renal replacement therapyBroeker, Astrid, Vossen, Matthias G., Thalhammer, Florian, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Wicha, Sebastian G. (2020). An Integrated Dialysis Pharmacometric (IDP) model to evaluate the pharmacokinetics in patients undergoing renal replacement therapy. Pharmaceutical Research, 37 (6) 96, 96. doi: 10.1007/s11095-020-02832-w |
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2020 Journal Article Pharmacokinetics of sulfamethoxazole and trimethoprim during veno-venous extracorporeal membrane oxygenation: a case reportDhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2020). Pharmacokinetics of sulfamethoxazole and trimethoprim during veno-venous extracorporeal membrane oxygenation: a case report. Pharmacotherapy, 40 (7) phar.2413, 713-717. doi: 10.1002/phar.2413 |
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2020 Journal Article The clinical relevance of oliguria in the critically ill patient: Analysis of a large observational databaseVincent, Jean-Louis, Ferguson, Andrew, Pickkers, Peter, Jakob, Stephan M., Jaschinski, Ulrich, Almekhlafi, Ghaleb A., Leone, Marc, Mokhtari, Majid, Fontes, Luis E., Bauer, Philippe R., Sakr, Yasser, Tomas, Esmael, Bibonge, Eric Amisi, Charra, Boubaker, Faroudy, Mamoun, Doedens, Linda, Farina, Zane, Adler, David, Balkema, Cecile, Kok, Adri, Alaya, Sami, Gharsallah, Hedi, Muzha, Dritan, Temelkov, Atanas, Georgiev, Georgi, Simeonov, Georgi, Tsaryanski, Georgi, Georgiev, Silvi, Seliman, Ali ... for the ICON Investigators (2020). The clinical relevance of oliguria in the critically ill patient: Analysis of a large observational database. Critical Care, 24 (1) 171. doi: 10.1186/s13054-020-02858-x |
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2020 Journal Article There is no fire without smoke! Pathophysiology and treatment of inhalational injury in burns: a narrative reviewHolley, Anthony D., Reade, Michael C., Lipman, Jeffrey and Cohen, Jeremy (2020). There is no fire without smoke! Pathophysiology and treatment of inhalational injury in burns: a narrative review. Anaesthesia and Intensive Care, 48 (2), 0310057X2091328-122. doi: 10.1177/0310057x20913282 |
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2020 Journal Article On-site therapeutic drug monitoringAtes, H. Ceren, Roberts, Jason A., Lipman, Jeffrey, Cass, Anthony E.G., Urban, Gerald A. and Dincer, Can (2020). On-site therapeutic drug monitoring. Trends in Biotechnology, 38 (11), 1262-1277. doi: 10.1016/j.tibtech.2020.03.001 |
