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2026

Journal Article

2401-P: Genetic Regulation of Molecular Traits Enhances Precision Risk Stratification in Youth-Onset Type 2 Diabetes

D'ANTONIO, MATTEO, BJORNSTAD, PETTER, JI CHOI, YE, PYLE, LAURA, DAS, VIVEK, GRAMS, MORGAN, KELSEY, MEGAN, NELSON, ROBERT, SRINIVASAN, SHYLAJA, SULEK, KAROLINA, KIRYLUK, KRZYSZTOF, GOODRICH, JESSE, GORDIN, DANIEL, NGUYEN, ELIZABETH D., LAFFEL, LORI M., FORBES, JOSEPHINE M., HAMPSON, HAILEY, RAMESH, SHIVANI, WEISSENKAMPEN, JAMES D., NARONGKIATIKHUN, PHOOM, TOMMERDAHL, KALIE, COLE, JOANNE, KARIHALOO, ANIL and LEIDHOLT, SAVANAH L. (2026). 2401-P: Genetic Regulation of Molecular Traits Enhances Precision Risk Stratification in Youth-Onset Type 2 Diabetes. Diabetes, 75 (Supplement_1) 2401-P. doi: 10.2337/db26-2401-p

2401-P: Genetic Regulation of Molecular Traits Enhances Precision Risk Stratification in Youth-Onset Type 2 Diabetes

2026

Journal Article

Mitochondrial Alterations and CKD

Pinzon-Cortes, Jairo A., Narongkiatikhun, Phoom, Yuan, Long, Meister, Jaroslawna, Hampson, Hailey, van Raalte, Daniël, Blondin, Denis P., Capozzi, Megan, Sweet, Ian R., Nelson, Robert G., Jandeleit-Dahm, Karin, Forbes, Josephine M., Cooper, Mark E. and Bjornstad, Petter (2026). Mitochondrial Alterations and CKD. American Journal of Kidney Diseases. doi: 10.1053/j.ajkd.2026.01.021

Mitochondrial Alterations and CKD

2026

Journal Article

Process of co-designing an Aboriginal and Torres Strait Islander longitudinal birth cohort study (The Strong Families Study)

Massi, Luciana, Smith, Davina, Mohamed Ahmed, Salma, Weatherall, Loretta, Friday, Rhiannon, Dorey, Emily S., Rooney, Rebecca, Reid, Natasha, Wheeler, Kai, Boyd, Roslyn N., Benfer, Katherine, Whittingham, Koa, Callaway, Leonie, Ware, Robert S., Clifton, Vicki, Martin, Elizabeth, Robinson, Paul, Forbes, Josephine, Singh, Gurmeet, Hermith-Ramirez, Diana, Marriott, Rhonda, Eades, Anne-Marie, Toombs, Maree, Eades, Sandra, Rae, Kym M. and Strong Families Study Indigenous Steering Committee (2026). Process of co-designing an Aboriginal and Torres Strait Islander longitudinal birth cohort study (The Strong Families Study). Codesign, 1-25. doi: 10.1080/15710882.2026.2675669

Process of co-designing an Aboriginal and Torres Strait Islander longitudinal birth cohort study (The Strong Families Study)

2025

Journal Article

Round and round we go: phosphoenolpyruvate carboxykinase 1 (PCK1) in cataplerosis, mitochondrial, and kidney health

Sullivan, Mitchell A. and Forbes, Josephine M. (2025). Round and round we go: phosphoenolpyruvate carboxykinase 1 (PCK1) in cataplerosis, mitochondrial, and kidney health. Kidney International, 108 (5), 738-740. doi: 10.1016/j.kint.2025.08.006

Round and round we go: phosphoenolpyruvate carboxykinase 1 (PCK1) in cataplerosis, mitochondrial, and kidney health

2025

Journal Article

Type 1 diabetes mellitus prevention: present and future

Henriques, Francisca L., Buckle, Irina and Forbes, Josephine M. (2025). Type 1 diabetes mellitus prevention: present and future. Nature Reviews Endocrinology, 21 (10), 608-622. doi: 10.1038/s41574-025-01128-6

Type 1 diabetes mellitus prevention: present and future

2025

Journal Article

Association between enteral carboxymethyllysine intake and daily glycemic variability in critically ill adults: a retrospective cohort study

Doola, Ra'eesa, Griffin, Alison, Forbes, Josephine M., Kruger, Peter S., Deane, Adam M., Schalkwijk, Casper G. and White, Kyle C. (2025). Association between enteral carboxymethyllysine intake and daily glycemic variability in critically ill adults: a retrospective cohort study. Journal of Parenteral and Enteral Nutrition, 49 (3), 324-331. doi: 10.1002/jpen.2727

Association between enteral carboxymethyllysine intake and daily glycemic variability in critically ill adults: a retrospective cohort study

2025

Journal Article

Efficacy and safety of photobiomodulation in MELAS: protocol for a series of N-of-1 trials

Laakso, E-Liisa, Ewais, Tatjana, McMahon, Katie, Forbes, Josephine and Phillips, Liza (2025). Efficacy and safety of photobiomodulation in MELAS: protocol for a series of N-of-1 trials. Journal of Clinical Medicine, 14 (6) 2047, 2047. doi: 10.3390/jcm14062047

Efficacy and safety of photobiomodulation in MELAS: protocol for a series of N-of-1 trials

2025

Journal Article

Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury

Giuliani, Kurt T. K., Nag, Purba, Adams, Benjamin C., Wang, Xiangju, Hong, Seokchan, Grivei, Anca, Johnston, Rebecca L., Waddell, Nicola, Ho, Kenneth K. C., Tian, Yilin, Khan, Muhammad Ali, Kim, Chang Seong, Ng, Monica S. Y., Gobe, Glenda, Ungerer, Jacobus P. J., Forbes, Josephine M., Healy, Helen G. and Kassianos, Andrew J. (2025). Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury. Cell Death and Disease, 16 (1) 61, 1-12. doi: 10.1038/s41419-025-07386-6

Human proximal tubular epithelial cell interleukin-1 receptor signalling triggers G2/M arrest and cellular senescence during hypoxic kidney injury

2024

Journal Article

Kidney hyperfiltration and mitochondrial changes are associated with eGFR decline in young people with type 1 diabetes

Pham, Uyen N., Pryke, Alison, Baskerville, Tracey, Griffin, Alison, Whiddett, Rani O., Fotheringham, Amelia K., Sullivan, Mitchell A., Nisbet, Janelle, Phillips, Liza, Francis, Ross S., Davis, Elizabeth, Jones, Timothy W., Cameron, Fergus, Couper, Jennifer, Benitez-Aguirre, Paul, Craig, Maria, Johnson, David W., Dalton, R. Neil, Marcovecchio, M. Loredana, Cotterill, Andrew, Barrett, Helen L., Donaghue, Kim C. and Forbes, Josephine M. (2024). Kidney hyperfiltration and mitochondrial changes are associated with eGFR decline in young people with type 1 diabetes. The Journal of Clinical Endocrinology and Metabolism, 110 (8), 2243-2251. doi: 10.1210/clinem/dgae787

Kidney hyperfiltration and mitochondrial changes are associated with eGFR decline in young people with type 1 diabetes

2024

Journal Article

Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation

Sourris, Karly C., Ding, Yi, Maxwell, Scott S., Al-sharea, Annas, Kantharidis, Phillip, Mohan, Muthukumar, Rosado, Carlos J., Penfold, Sally A., Haase, Claus, Xu, Yangsong, Forbes, Josephine M., Crawford, Simon, Ramm, Georg, Harcourt, Brooke E., Jandeleit-Dahm, Karin, Advani, Andrew, Murphy, Andrew J., Timmermann, Daniel B., Karihaloo, Anil, Knudsen, Lotte Bjerre, El-Osta, Assam, Drucker, Daniel J., Cooper, Mark E. and Coughlan, Melinda T. (2024). Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation. Kidney International, 105 (1), 132-149. doi: 10.1016/j.kint.2023.09.029

Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation

2023

Journal Article

Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes

Leung, Sherman S., Lenchik, Nataliya, Mathews, Clayton, Pugliese, Alberto, McCarthy, Domenica A., Le Bagge, Selena, Ewing, Adam, Harris, Mark, Radford, Kristen J., Borg, Danielle J., Gerling, Ivan and Forbes, Josephine M. (2023). Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes. Scientific Reports, 13 (1) 12948, 1-15. doi: 10.1038/s41598-023-39243-x

Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes

2022

Journal Article

RAGE antagonism with azeliragon improves xenograft rejection by T cells in humanized mice

Joshi, Aditi A., Wu, Ying, Deng, Songyan, Preston-Hurlburt, Paula, Forbes, Josephine M. and Herold, Kevan C. (2022). RAGE antagonism with azeliragon improves xenograft rejection by T cells in humanized mice. Clinical Immunology, 245 109165, 1-6. doi: 10.1016/j.clim.2022.109165

RAGE antagonism with azeliragon improves xenograft rejection by T cells in humanized mice

2022

Journal Article

Advanced glycation end products and inflammation in type 1 diabetes development

Du, Chenping, Whiddett, Rani O., Buckle, Irina, Chen, Chen, Forbes, Josephine M. and Fotheringham, Amelia K. (2022). Advanced glycation end products and inflammation in type 1 diabetes development. Cells, 11 (21) 3503, 1-18. doi: 10.3390/cells11213503

Advanced glycation end products and inflammation in type 1 diabetes development

2022

Journal Article

Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells

Giuliani, Kurt T. K., Grivei, Anca, Nag, Purba, Wang, Xiangju, Rist, Melissa, Kildey, Katrina, Law, Becker, Ng, Monica S., Wilkinson, Ray, Ungerer, Jacobus, Forbes, Josephine M., Healy, Helen and Kassianos, Andrew J. (2022). Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells. Cell Death and Disease, 13 (8) 739, 1-13. doi: 10.1038/s41419-022-05191-z

Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells

2022

Journal Article

Mitochondrial dysfunction in individuals with diabetic kidney disease: a systematic review

Flemming, Nicole, Pernoud, Laura, Forbes, Josephine and Gallo, Linda (2022). Mitochondrial dysfunction in individuals with diabetic kidney disease: a systematic review. Cells, 11 (16) 2481, 1-24. doi: 10.3390/cells11162481

Mitochondrial dysfunction in individuals with diabetic kidney disease: a systematic review

2022

Journal Article

Advanced glycation end products (AGEs) and chronic kidney disease: does the modern diet AGE the kidney?

Fotheringham, Amelia K., Gallo, Linda A., Borg, Danielle J. and Forbes, Josephine M. (2022). Advanced glycation end products (AGEs) and chronic kidney disease: does the modern diet AGE the kidney?. Nutrients, 14 (13) 2675, 1-28. doi: 10.3390/nu14132675

Advanced glycation end products (AGEs) and chronic kidney disease: does the modern diet AGE the kidney?

2022

Journal Article

Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells

Leung, Sherman S., Borg, Danielle J., McCarthy, Domenica A., Boursalian, Tamar E., Cracraft, Justen, Zhuang, Aowen, Fotheringham, Amelia K., Flemming, Nicole, Watkins, Thomas, Miles, John J., Groop, Per-Henrik, Scheijen, Jean L., Schalkwijk, Casper G., Steptoe, Raymond J., Radford, Kristen J., Knip, Mikael and Forbes, Josephine M. (2022). Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells. Diabetes, 71 (9), 1994-2008. doi: 10.2337/db22-0177

Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells

2022

Journal Article

The impact of a modified carbohydrate formula, and its constituents, on glycaemic control and inflammatory markers: a nested mechanistic sub-study

Doola, Ra'eesa, Deane, Adam M., Barrett, Helen L., Okano, Satomi, Tolcher, Debbie M., Gregory, Kye, Coombes, Jeff S., Schalkwijk, Casper, Todd, Alwyn S., Forbes, Josephine M. and Sturgess, David J. (2022). The impact of a modified carbohydrate formula, and its constituents, on glycaemic control and inflammatory markers: a nested mechanistic sub-study. Journal of Human Nutrition and Dietetics, 35 (3), 455-465. doi: 10.1111/jhn.12959

The impact of a modified carbohydrate formula, and its constituents, on glycaemic control and inflammatory markers: a nested mechanistic sub-study

2021

Journal Article

Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure

Fotheringham, Amelia K., Solon-Biet, Samantha M., Bielefeldt-Ohmann, Helle, McCarthy, Domenica A., McMahon, Aisling C., Ruohonen, Kari, Li, Isaac, Sullivan, Mitchell A., Whiddett, Rani O., Borg, Danielle J., Cogger, Victoria C., Ballard, William O., Turner, Nigel, Melvin, Richard G., Raubenheimer, David, Le Couteur, David G., Simpson, Stephen J. and Forbes, Josephine M. (2021). Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure. iScience, 24 (11) 103308, 103308. doi: 10.1016/j.isci.2021.103308

Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure

2021

Journal Article

T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes

Forbes, Josephine M., McCarthy, Domenica A., Kassianos, Andrew J., Baskerville, Tracey, Fotheringham, Amelia J., Giuliani, Kurt T. K., Grivei, Anca, Murphy, Andrew J., Flynn, Michelle C., Sullivan, Mitchell A., Chandrashekar, Preeti, Whiddett, Rani, Radford, Kristen J., Flemming, Nicole, Beard, Sam S., D’Silva, Neisha, Nisbet, Janelle, Morton, Adam, Teasdale, Stephanie, Russell, Anthony, Isbel, Nicole, Jones, Timothy, Couper, Jennifer, Healy, Helen, Harris, Mark, Donaghue, Kim, Johnson, David W., Cotterill, Andrew, Barrett, Helen L. and O’Moore-Sullivan, Trisha (2021). T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes. Diabetes, 70 (8), 1754-1766. doi: 10.2337/db20-1081

T cell expression and release of kidney injury molecule-1 in response to glucose variations initiates kidney injury in early diabetes